Exploring the active site of acyl homoserine lactones-dependent transcriptional regulators with bacterial quorum sensing modulators using molecular mechanics and docking studies

Journal of Molecular Graphics and Modelling

Volumn 26, Issue 2, 2007, Pages 581-590

  Soulère, Laurent ^a,b,c   Frezza, Marine ^a,b,c   Queneau, Yves ^a,b,c   Doutheau, Alain ^a,b,c  

^a UNIVERSITÉ LYON 1   (France)

^b CPE LYON   (France)

^c UNIVERSITÉ DE LYON   (France)

Author keywords

AHLs; Conformational analysis; Docking; Modulators; Quorum sensing; TraR

Indexed keywords

BACTERIA; CONFORMATIONS; DOCKING; ESTERS; MOLECULAR MECHANICS; MOLECULAR MODELING;

ACTIVE SITE; QUORUM SENSING; STRUCTURAL HOMOLOGY; TRANSCRIPTIONAL REGULATORS;

TRANSCRIPTION FACTORS;

AMIDE; ASPARTIC ACID; BACTERIAL PROTEIN; LACTONE DERIVATIVE; N ACYLHOMOSERINE LACTONE; N SULFONYL HOMOSERINE LACTONE; PROTEIN LASR; PROTEIN SDIA; PROTEIN TRAR; SULFONAMIDE; TRANSCRIPTION FACTOR LUXR; TYROSINE; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; HYDROGEN BOND; MOLECULAR DOCKING; MOLECULAR MECHANICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; QUORUM SENSING; STRUCTURAL HOMOLOGY; STRUCTURE ACTIVITY RELATION;

BACTERIA (MICROORGANISMS);

EID: 34548317426     PISSN: 10933263     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmgm.2007.04.004     Document Type: Article

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