Alleviation of insulitis and moderation of diabetes in NOD mice following treatment with a synthetic Pseudomonas aeruginosa signal molecule, N-(3-oxododecanoyl)-L-homoserine lactone

Acta Diabetologica

Volumn 42, Issue 3, 2005, Pages 119-122

  Pritchard, D I ^a   Todd, I ^b   Brown, A ^a   Bycroft, B W ^a   Chhabra, S R ^a   Williams, P ^a   Wood, P ^c  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Autoimmunity; Mononuclear leucocytes; Pancreas; Therapeutics

Indexed keywords

ANTIDIABETIC AGENT; BACTERIUM LIPOPOLYSACCHARIDE; DIMETHYL SULFOXIDE; INTERLEUKIN 12; LACTONE DERIVATIVE; N (3 OXODODECANOYL)HOMOSERINE LACTONE; N (3 OXOHEXANOYL)HOMOSERINE LACTONE; N (3 OXOTRIDECANOYL)HOMOSERINE LACTONE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; FEMALE; IMMUNOMODULATION; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; MACROPHAGE ACTIVATION; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SIGNAL TRANSDUCTION; TH2 CELL;

4-BUTYROLACTONE; ADJUVANTS, IMMUNOLOGIC; ANIMALS; DIABETES MELLITUS; DIMETHYL SULFOXIDE; DISEASE MODELS, ANIMAL; HOMOSERINE; INFLAMMATION; ISLETS OF LANGERHANS; MICE; MICE, INBRED NOD; PANCREATIC DISEASES; PSEUDOMONAS AERUGINOSA;

EID: 27644507318     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-005-0190-2     Document Type: Article

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