메뉴 건너뛰기




Volumn 43, Issue 1, 2010, Pages 56-66

The role of scaffold proteins in JNK signalling

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PROTEIN SH3; RAF PROTEIN; SCAFFOLD PROTEIN; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INTERACTING PROTEIN 1; STRESS ACTIVATED PROTEIN KINASE INTERACTING PROTEIN 2; STRESS ACTIVATED PROTEIN KINASE INTERACTING PROTEIN 3; STRESS ACTIVATED PROTEIN KINASE INTERACTING ZIPPER PROTEIN; UNCLASSIFIED DRUG;

EID: 73349108440     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2009.00654.x     Document Type: Review
Times cited : (51)

References (92)
  • 1
    • 0344393408 scopus 로고    scopus 로고
    • Regulation of MAP kinase signalling modules by scaffold proteins in mammals
    • Morrison DK, Davis RJ (2003) Regulation of MAP kinase signalling modules by scaffold proteins in mammals. Annu. Rev. Cell Dev. Biol. 19, 91 118.
    • (2003) Annu. Rev. Cell Dev. Biol. , vol.19 , pp. 91-118
    • Morrison, D.K.1    Davis, R.J.2
  • 3
    • 2442469277 scopus 로고    scopus 로고
    • Targeting MAPK signalling: Prometheus fire or pandoras box
    • Boldt S, Kolch W (2004) Targeting MAPK signalling: prometheus fire or pandoras box. Curr. Pharm. Des. 10, 1885 1905.
    • (2004) Curr. Pharm. Des. , vol.10 , pp. 1885-1905
    • Boldt, S.1    Kolch, W.2
  • 4
    • 34248372929 scopus 로고    scopus 로고
    • Macrophage glucocorticoid receptors regulate Toll like receptor 4-mediated inflammatory responses by selective inhibition of p38 MAP kinase
    • Bhattacharyya S, Brown DE, Brewer JA, Vogt SK, Muglia LJ (2007) Macrophage glucocorticoid receptors regulate Toll like receptor 4-mediated inflammatory responses by selective inhibition of p38 MAP kinase. Blood 109, 4313 4319.
    • (2007) Blood , vol.109 , pp. 4313-4319
    • Bhattacharyya, S.1    Brown, D.E.2    Brewer, J.A.3    Vogt, S.K.4    Muglia, L.J.5
  • 5
    • 0027983908 scopus 로고
    • Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S cerevisiae
    • Choi KY, Satterberg B, Lyons DM, Elion EA (1994) Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S cerevisiae. Cell 78, 499 512.
    • (1994) Cell , vol.78 , pp. 499-512
    • Choi, K.Y.1    Satterberg, B.2    Lyons, D.M.3    Elion, E.A.4
  • 6
    • 0027991228 scopus 로고
    • Complexes between STE5 and components of the pheromone responsive mitogen activated Protein kinase module
    • Marcus S, Polverino A, Barr M, Wigler M (1994) Complexes between STE5 and components of the pheromone responsive mitogen activated Protein kinase module. Proc. Natl. Acad. Sci. USA 91, 7762 7766.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7762-7766
    • Marcus, S.1    Polverino, A.2    Barr, M.3    Wigler, M.4
  • 7
    • 0035195491 scopus 로고    scopus 로고
    • The Ste5p scaffold
    • Elton EA (2001) The Ste5p scaffold. J. Cell Sci. 114, 3967 3978.
    • (2001) J. Cell Sci. , vol.114 , pp. 3967-3978
    • Elton, E.A.1
  • 8
    • 0034009390 scopus 로고    scopus 로고
    • Signal transduction; Hanging on a scaffold
    • Burack WR, Shaw AS (2000) Signal transduction; hanging on a scaffold. Curr. Opin. Cell Biol. 12, 211 216.
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 211-216
    • Burack, W.R.1    Shaw, A.S.2
  • 10
    • 0030835610 scopus 로고    scopus 로고
    • A multivalent PDZ domain protein assembles signalling complexes in a G-protein coupled cascade
    • Tsunoda S, Sierralta J, Sun YM, Bodner R, Suzuki E, Becker A et al. (1997) A multivalent PDZ domain protein assembles signalling complexes in a G-protein coupled cascade. Nature 388, 243 249.
    • (1997) Nature , vol.388 , pp. 243-249
    • Tsunoda, S.1    Sierralta, J.2    Sun, Y.M.3    Bodner, R.4    Suzuki, E.5    Becker, A.6
  • 11
    • 0033559804 scopus 로고    scopus 로고
    • Organisation of kinases, phosphatases and receptor signalling complexes
    • Schillace RV, Scott JD (1999) Organisation of kinases, phosphatases and receptor signalling complexes. J. Clin. Invest. 103, 761 765.
    • (1999) J. Clin. Invest. , vol.103 , pp. 761-765
    • Schillace, R.V.1    Scott, J.D.2
  • 12
    • 0033534533 scopus 로고    scopus 로고
    • Adaptors and molecular scaffolds in immune cell signalling
    • Rudd CE (1999) Adaptors and molecular scaffolds in immune cell signalling. Cell 96, 5 8.
    • (1999) Cell , vol.96 , pp. 5-8
    • Rudd, C.E.1
  • 13
    • 4644273095 scopus 로고    scopus 로고
    • Counting on mitogen activated protein kinases ERKs 3,4,5,6,7 and 8
    • Bogoyevitch MA, Court NW (2004) Counting on mitogen activated protein kinases ERKs 3,4,5,6,7 and 8. Cell. Signal. 16, 1345 1354.
    • (2004) Cell. Signal. , vol.16 , pp. 1345-1354
    • Bogoyevitch, M.A.1    Court, N.W.2
  • 14
    • 33748942862 scopus 로고    scopus 로고
    • The isoform specific functions of the c-Jun N-terminal Kinases (JNKs) differences revealed by gene targeting
    • Bogoyevitch MA (2006) The isoform specific functions of the c-Jun N-terminal Kinases (JNKs) differences revealed by gene targeting. Bioessays 28, 923 934.
    • (2006) Bioessays , vol.28 , pp. 923-934
    • Bogoyevitch, M.A.1
  • 15
    • 34547228831 scopus 로고    scopus 로고
    • Atypical mitogen activated protein kinases. Structure, regulation and function
    • Coulombe P, Meloche S (2006) Atypical mitogen activated protein kinases. Structure, regulation and function. Biochim. Biophys. Acta 1773, 1376 1387.
    • (2006) Biochim. Biophys. Acta , vol.1773 , pp. 1376-1387
    • Coulombe, P.1    Meloche, S.2
  • 16
    • 19644367000 scopus 로고    scopus 로고
    • Activation and signalling of the p38 MAP kinase pathway
    • Zarubin T, Han J (2005) Activation and signalling of the p38 MAP kinase pathway. Cell Res. 15, 11 18.
    • (2005) Cell Res. , vol.15 , pp. 11-18
    • Zarubin, T.1    Han, J.2
  • 18
    • 0032694245 scopus 로고    scopus 로고
    • JSAP1, a novel jun N-terminal protein kinase (JNK binding protein that functions as a Scaffold factor in the JNK signalling pathway)
    • Ito M, Yoshioka K, Akechi M, Yamashita S, Takamatsu N, Sugiyama K et al. (1999) JSAP1, a novel jun N-terminal protein kinase (JNK binding protein that functions as a Scaffold factor in the JNK signalling pathway). Mol. Cell. Biol. 19, 7539 7548.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7539-7548
    • Ito, M.1    Yoshioka, K.2    Akechi, M.3    Yamashita, S.4    Takamatsu, N.5    Sugiyama, K.6
  • 19
    • 26144481268 scopus 로고    scopus 로고
    • Immunogenicity and contraceptive potential of recombinant human sperm associated antigen (SPAG9)
    • Jagadish N, Rana R, Mishra D, Garg M, Chaurasiya D, Hasegawa A et al. (2005) Immunogenicity and contraceptive potential of recombinant human sperm associated antigen (SPAG9). J. Reprod. Immunol. 67, 69 76.
    • (2005) J. Reprod. Immunol. , vol.67 , pp. 69-76
    • Jagadish, N.1    Rana, R.2    Mishra, D.3    Garg, M.4    Chaurasiya, D.5    Hasegawa, A.6
  • 20
    • 16344363064 scopus 로고    scopus 로고
    • Characterisation of a novel human sperm associated antigen 9 (SPAG9) having structural homology with c-Jun N-terminal kinase interacting protein
    • Jagadish N, Rana R, Selvi R, Mishra D, Garg M, Yadav S et al. (2005) Characterisation of a novel human sperm associated antigen 9 (SPAG9) having structural homology with c-Jun N-terminal kinase interacting protein. Biochem. J. 389, 73 82.
    • (2005) Biochem. J. , vol.389 , pp. 73-82
    • Jagadish, N.1    Rana, R.2    Selvi, R.3    Mishra, D.4    Garg, M.5    Yadav, S.6
  • 21
    • 15044357454 scopus 로고    scopus 로고
    • Role of JIP4 scaffold protein in the regulation of mitogen activated protein kinase signalling pathways
    • Kelkar N, Standen CL, Davis RJ (2005) Role of JIP4 scaffold protein in the regulation of mitogen activated protein kinase signalling pathways. Mol. Cell. Biol. 25, 2733 2743.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 2733-2743
    • Kelkar, N.1    Standen, C.L.2    Davis, R.J.3
  • 22
    • 0037195113 scopus 로고    scopus 로고
    • JLP, a scaffolding protein that tethers JNK/p38MAPK signalling modules and transcription factors
    • Lee CL, Onesime D, Reddy CD, Dhanasekaran N, Reddy EP (2002) JLP, a scaffolding protein that tethers JNK/p38MAPK signalling modules and transcription factors. Proc. Natl. Acad. Sci. USA 99, 14189 14194.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 14189-14194
    • Lee, C.L.1    Onesime, D.2    Reddy, C.D.3    Dhanasekaran, N.4    Reddy, E.P.5
  • 23
    • 0032473569 scopus 로고    scopus 로고
    • A new rac target POSH is an SH3 containing scaffold protein involved in the JNK and NF kappaB signalling pathways
    • Tapon N, Nagata K, Lamarche N, Hall A (1998) A new rac target POSH is an SH3 containing scaffold protein involved in the JNK and NF kappaB signalling pathways. EMBO J. 17, 1395 1404.
    • (1998) EMBO J. , vol.17 , pp. 1395-1404
    • Tapon, N.1    Nagata, K.2    Lamarche, N.3    Hall, A.4
  • 24
    • 0032422785 scopus 로고    scopus 로고
    • Structural organisation of MAP kinase signalling modules by scafold proteins in yeast and mammals
    • Whitmarsh AJ, Davis RJ (1998) Structural organisation of MAP kinase signalling modules by scafold proteins in yeast and mammals. Trends Biochem. Sci. 23, 481 485.
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 481-485
    • Whitmarsh, A.J.1    Davis, R.J.2
  • 25
    • 0033613273 scopus 로고    scopus 로고
    • Signal transduction by MAP kinases; Regulation by phosphorylation dependent switches
    • Whitmarsh AJ, Davis RJ (1999) Signal transduction by MAP kinases; regulation by phosphorylation dependent switches. Sci. STKE 1999, PE1.
    • (1999) Sci. STKE , vol.1999 , pp. 1
    • Whitmarsh, A.J.1    Davis, R.J.2
  • 29
    • 0038701654 scopus 로고    scopus 로고
    • The JNK interacting protein 1 scaffold protein targets MAPK phosphatase 7 to dephosphorylate JNK
    • Willoughby EA, Perkins GR, Collins MK, Whitmarsh AJ (2003) The JNK interacting protein 1 scaffold protein targets MAPK phosphatase 7 to dephosphorylate JNK. J. Biol. Chem. 278, 10731 10736.
    • (2003) J. Biol. Chem. , vol.278 , pp. 10731-10736
    • Willoughby, E.A.1    Perkins, G.R.2    Collins, M.K.3    Whitmarsh, A.J.4
  • 30
    • 0033520918 scopus 로고    scopus 로고
    • Interactuion of c-Jun amino-terminal kinase interacting protein 1 with p190 rhoGEF and its localisation in differentiated neurons
    • Meyer D, Liu A, Margolis B (1999) Interactuion of c-Jun amino-terminal kinase interacting protein 1 with p190 rhoGEF and its localisation in differentiated neurons. J. Biol. Chem. 174, 35113 35118.
    • (1999) J. Biol. Chem. , vol.174 , pp. 35113-35118
    • Meyer, D.1    Liu, A.2    Margolis, B.3
  • 32
    • 13944281035 scopus 로고    scopus 로고
    • Stress kinases involved in tau phosphorylation in Alzheimers disease, tauopathies and APP transgenic mice
    • Ferrer I (2004) Stress kinases involved in tau phosphorylation in Alzheimers disease, tauopathies and APP transgenic mice. Neurotox. Res. 6, 469 475.
    • (2004) Neurotox. Res. , vol.6 , pp. 469-475
    • Ferrer, I.1
  • 33
    • 0036462590 scopus 로고    scopus 로고
    • Jun NH2 terminal kinase interacting protein 1 (JIP1) binds to the cytoplasmic domain of the Alzheimer beta amyloid precursorprotein (APP)
    • Scheinfeld MH, Roncarati R, Vito P, Lopez PA, Abdallah M, d′Adamio L (2002) Jun NH2 terminal kinase interacting protein 1 (JIP1) binds to the cytoplasmic domain of the Alzheimer beta amyloid precursorprotein (APP). J. Biol. Chem. 277, 3767 3775.
    • (2002) J. Biol. Chem. , vol.277 , pp. 3767-3775
    • Scheinfeld, M.H.1    Roncarati, R.2    Vito, P.3    Lopez, P.A.4    Abdallah, M.5    Dadamio, L.6
  • 34
    • 0342858815 scopus 로고    scopus 로고
    • CDNA cloning and mapping of a novel islet brain/JNK interacting protein
    • Negri S, Oberson A, Steinmann M, Sauser C, Nicod P, Waeber G et al. (2000) cDNA cloning and mapping of a novel islet brain/JNK interacting protein. Genomics 64, 324 330.
    • (2000) Genomics , vol.64 , pp. 324-330
    • Negri, S.1    Oberson, A.2    Steinmann, M.3    Sauser, C.4    Nicod, P.5    Waeber, G.6
  • 35
    • 0036265520 scopus 로고    scopus 로고
    • Interaction of Rac exchange factors TIAM1 and RasGRF with a scaffold for the p38 mitogen-activated protein kinase cascade
    • Buchsbaum RJ, Connolly BA, Feig LA (2002) Interaction of Rac exchange factors TIAM1 and RasGRF with a scaffold for the p38 mitogen-activated protein kinase cascade. Mol. Cell. Biol. 22, 4073 4085.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4073-4085
    • Buchsbaum, R.J.1    Connolly, B.A.2    Feig, L.A.3
  • 36
    • 0037147297 scopus 로고    scopus 로고
    • Fibroblast growth factor homologous factors and the islet brain scaffold protein regulate activation of a stress activated protein kinase
    • Schoorlemmer J, Goldfarb M (2002) Fibroblast growth factor homologous factors and the islet brain scaffold protein regulate activation of a stress activated protein kinase. J. Biol. Chem. 277, 49111 49119.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49111-49119
    • Schoorlemmer, J.1    Goldfarb, M.2
  • 37
    • 0033971177 scopus 로고    scopus 로고
    • Interaction of a mitogen-activated protein kinase signalling module with the neuronal protein JIP3
    • Kelkar N, Gupta S, Dickens M, Davis RJ (2000) Interaction of a mitogen-activated protein kinase signalling module with the neuronal protein JIP3. Mol. Cell. Biol. 20, 1030 1043.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1030-1043
    • Kelkar, N.1    Gupta, S.2    Dickens, M.3    Davis, R.J.4
  • 38
    • 0037174938 scopus 로고    scopus 로고
    • Phosphorylation dependent scaffolding role of JSAP1/JIP-3 in the ASK1/JNK signalling pathway. A new mode of regulation of the MAP kinase cascade
    • Matsuura H, Nishitoh H, Takeda K, Matsuzawa A, Amagasa T, Ito M et al. (2002) Phosphorylation dependent scaffolding role of JSAP1/JIP-3 in the ASK1/JNK signalling pathway. A new mode of regulation of the MAP kinase cascade. J. Biol. Chem. 277, 40703 40709.
    • (2002) J. Biol. Chem. , vol.277 , pp. 40703-40709
    • Matsuura, H.1    Nishitoh, H.2    Takeda, K.3    Matsuzawa, A.4    Amagasa, T.5    Ito, M.6
  • 39
    • 0034687129 scopus 로고    scopus 로고
    • Isoforms of JSAP1 scaffold protein generated through alternative splicing
    • Ito M, Akechi M, Hirose R, Ichimura M, Takamatsu N, Xu P et al. (2000) Isoforms of JSAP1 scaffold protein generated through alternative splicing. Gene 255, 229 234.
    • (2000) Gene , vol.255 , pp. 229-234
    • Ito, M.1    Akechi, M.2    Hirose, R.3    Ichimura, M.4    Takamatsu, N.5    Xu, P.6
  • 40
    • 0034704171 scopus 로고    scopus 로고
    • A scaffold protein in the c-Jun NH2 terminal kinase signalling pathways suppresses the extracellular signal regulated kinase signalling pathways
    • Kuboki Y, Ito M, Takamatsu N, Yamamoto KI, Shiba T, Yoshioka K (2000) A scaffold protein in the c-Jun NH2 terminal kinase signalling pathways suppresses the extracellular signal regulated kinase signalling pathways. J. Biol. Chem. 275, 39815 39818.
    • (2000) J. Biol. Chem. , vol.275 , pp. 39815-39818
    • Kuboki, Y.1    Ito, M.2    Takamatsu, N.3    Yamamoto, K.I.4    Shiba, T.5    Yoshioka, K.6
  • 41
    • 0037136721 scopus 로고    scopus 로고
    • A scaffold protein in the jun N-terminal kinase signalling pathway is associated with focal adhesion kinase and tyrosine phosphorylated
    • Takino T, Yoshioka K, Miyamori H, Yamada KM, Sato H (2002) A scaffold protein in the jun N-terminal kinase signalling pathway is associated with focal adhesion kinase and tyrosine phosphorylated. Oncogene 21, 6488 6497.
    • (2002) Oncogene , vol.21 , pp. 6488-6497
    • Takino, T.1    Yoshioka, K.2    Miyamori, H.3    Yamada, K.M.4    Sato, H.5
  • 42
    • 27844451510 scopus 로고    scopus 로고
    • JSAP1/JIP3 cooperates with focal adhesion kinase to regulate c-jun N-terminal kinase and cell migration
    • Takino T, Nakada M, Miyamori H, Watanabe Y, Sato T, Gantulga D et al. (2005) JSAP1/JIP3 cooperates with focal adhesion kinase to regulate c-jun N-terminal kinase and cell migration. J. Biol. Chem. 280, 37772 37781.
    • (2005) J. Biol. Chem. , vol.280 , pp. 37772-37781
    • Takino, T.1    Nakada, M.2    Miyamori, H.3    Watanabe, Y.4    Sato, T.5    Gantulga, D.6
  • 43
    • 0042236994 scopus 로고    scopus 로고
    • JNK interacting protein 3 associates with Toll like receptor 4 and is involved in LPS mediated JNK activation
    • Matsuguchi T, Masuda A, Sugimoto K, Nagai Y, Yoshikai Y (2003) JNK interacting protein 3 associates with Toll like receptor 4 and is involved in LPS mediated JNK activation. EMBO J. 22, 4455 4464.
    • (2003) EMBO J. , vol.22 , pp. 4455-4464
    • Matsuguchi, T.1    Masuda, A.2    Sugimoto, K.3    Nagai, Y.4    Yoshikai, Y.5
  • 44
    • 24044519684 scopus 로고    scopus 로고
    • JLP associates with kinesin light chain 1 through a novel leucine zipper like domain
    • Nguyen Q, Lee CM, Reddy EP (2005) JLP associates with kinesin light chain 1 through a novel leucine zipper like domain. J. Biol. Chem. 280, 30185 30191.
    • (2005) J. Biol. Chem. , vol.280 , pp. 30185-30191
    • Nguyen, Q.1    Lee, C.M.2    Reddy, E.P.3
  • 45
    • 33745597102 scopus 로고    scopus 로고
    • Endodermal differentiation of murine embryonic carcinoma cells by retinoic acid requires JLP a JNK scaffolding protein
    • Kashef K, Xu H, Reddy EP, Dhanasekaran DN (2006) Endodermal differentiation of murine embryonic carcinoma cells by retinoic acid requires JLP a JNK scaffolding protein. J. Cell. Biochem. 98, 715 722.
    • (2006) J. Cell. Biochem. , vol.98 , pp. 715-722
    • Kashef, K.1    Xu, H.2    Reddy, E.P.3    Dhanasekaran, D.N.4
  • 46
    • 27444442185 scopus 로고    scopus 로고
    • JNK interacting leucine zipper protein is a novel scaffolding protein is a novel scaffolding protein in the Ga13 signalling pathway
    • Kashef K, Lee CM, Ha JH, Reddy EP, Dhanasekaran DN (2005) JNK interacting leucine zipper protein is a novel scaffolding protein is a novel scaffolding protein in the Ga13 signalling pathway. Biochemistry 44, 14090 14096.
    • (2005) Biochemistry , vol.44 , pp. 14090-14096
    • Kashef, K.1    Lee, C.M.2    Ha, J.H.3    Reddy, E.P.4    Dhanasekaran, D.N.5
  • 47
    • 33744950092 scopus 로고    scopus 로고
    • Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs
    • Kukekov NV, Xu Z, Greene LA (2006) Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs. J. Biol. Chem. 281, 15517 15524.
    • (2006) J. Biol. Chem. , vol.281 , pp. 15517-15524
    • Kukekov, N.V.1    Xu, Z.2    Greene, L.A.3
  • 48
    • 0031450154 scopus 로고    scopus 로고
    • MEKK1 binds directly to the c-jun N-terminal kinases/stress activated protein kinases
    • Xu S, Cobb MH (1997) MEKK1 binds directly to the c-jun N-terminal kinases/stress activated protein kinases. J. Biol. Chem. 272, 32056 32060.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32056-32060
    • Xu, S.1    Cobb, M.H.2
  • 49
    • 17644402459 scopus 로고    scopus 로고
    • Transduction of receptor signals by beta-arrestins
    • Lefkovitz RJ, Shenoy SK (2005) Transduction of receptor signals by beta-arrestins. Science 308, 512 517.
    • (2005) Science , vol.308 , pp. 512-517
    • Lefkovitz, R.J.1    Shenoy, S.K.2
  • 50
    • 6944234874 scopus 로고    scopus 로고
    • Expression of JNK interacting protein JIP-1 is down regulated in liver from mouse embryos with a disrupted insulin like growth factor II gene
    • Rohbe L, Larsson M, Rising A, Grip S, Burns J, Engström W (2004) Expression of JNK interacting protein JIP-1 is down regulated in liver from mouse embryos with a disrupted insulin like growth factor II gene. In vivo 18, 643 648.
    • (2004) In Vivo , vol.18 , pp. 643-648
    • Rohbe, L.1    Larsson, M.2    Rising, A.3    Grip, S.4    Burns, J.5    Engström, W.6
  • 51
    • 0028408663 scopus 로고
    • Insulin like growth factors; Growth, transgenes and imprinting
    • Ward A, Bierke P, Pettersson E, Engström W (1994) Insulin like growth factors; growth, transgenes and imprinting. Zool. Sci. 11, 167 174.
    • (1994) Zool. Sci. , vol.11 , pp. 167-174
    • Ward, A.1    Bierke, P.2    Pettersson, E.3    Engström, W.4
  • 52
    • 73349100945 scopus 로고    scopus 로고
    • Transcriptional regulation and biological significance of the insulin like growth factor 2 gene
    • Engström W, Shokrai A, Otte K, Granerus M, Gessbo Å, Bierke P et al. (1998) Transcriptional regulation and biological significance of the insulin like growth factor 2 gene. Cell Prolif. 31, 1 16.
    • (1998) Cell Prolif. , vol.31 , pp. 1-16
    • Engström, W.1    Shokrai, A.2    Otte, K.3    Granerus, M.4    Å, G.5    Bierke, P.6
  • 54
    • 33645453109 scopus 로고    scopus 로고
    • Regulation of growth and metabolism by imprinted genes
    • Smith FM, Garfield AS, Ward A (2006) Regulation of growth and metabolism by imprinted genes. Cytogenet. Genome Res. 113, 279 291.
    • (2006) Cytogenet. Genome Res. , vol.113 , pp. 279-291
    • Smith, F.M.1    Garfield, A.S.2    Ward, A.3
  • 55
    • 17444391705 scopus 로고    scopus 로고
    • The JNK interacting protein JIP-1 and insulin like growth factor II genes are co-expressed in human embryonic tumours
    • Engström W, Rising A, Grip S (2005) The JNK interacting protein JIP-1 and insulin like growth factor II genes are co-expressed in human embryonic tumours. Anticancer Res. 25, 1075 1078.
    • (2005) Anticancer Res. , vol.25 , pp. 1075-1078
    • Engström, W.1    Rising, A.2    Grip, S.3
  • 56
    • 0035141416 scopus 로고
    • Insulin like growth factors i and II induce cell death in Wilms tumour cells
    • Granerus M, Johannisson A, Ekblom P, Engström W (1991) Insulin like growth factors I and II induce cell death in Wilms tumour cells. Mol. Pathol. 54, 30 35.
    • (1991) Mol. Pathol. , vol.54 , pp. 30-35
    • Granerus, M.1    Johannisson, A.2    Ekblom, P.3    Engström, W.4
  • 57
    • 69249181357 scopus 로고    scopus 로고
    • Expression of JNK interacting protein JIP-1 and insulin like growth factor II in Wilms tumour cell lines and primary Wilms Tumours
    • Engström W, Granerus M (2009) Expression of JNK interacting protein JIP-1 and insulin like growth factor II in Wilms tumour cell lines and primary Wilms Tumours. Anticancer Res. 29, 2467 2472.
    • (2009) Anticancer Res. , vol.29 , pp. 2467-2472
    • Engström, W.1    Granerus, M.2
  • 58
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP-kinases on apoptosis
    • Xia Z, Dickens M, Raingeaud J, Davis RJ (1995) Opposing effects of ERK and JNK-p38 MAP-kinases on apoptosis. Science 270, 1326 1331.
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4
  • 59
    • 0037330477 scopus 로고    scopus 로고
    • The kinase domain of MEKK1 induces apoptosis by dysregulation of MAP kinase pathways
    • Boldt S, Weidle UH, Kolch W (2003) The kinase domain of MEKK1 induces apoptosis by dysregulation of MAP kinase pathways. Exp. Cell Res. 283, 80 90.
    • (2003) Exp. Cell Res. , vol.283 , pp. 80-90
    • Boldt, S.1    Weidle, U.H.2    Kolch, W.3
  • 60
    • 0033063568 scopus 로고    scopus 로고
    • Defective liver formation and liver cell apoptosis in mice lacking the stress signalling kinase SEK1/MKK4
    • Nishina H, Vaz C, Billia P, Nghiem M, Sasaki T, de la Pompa JL (1999) Defective liver formation and liver cell apoptosis in mice lacking the stress signalling kinase SEK1/MKK4. Development 126, 505 516.
    • (1999) Development , vol.126 , pp. 505-516
    • Nishina, H.1    Vaz, C.2    Billia, P.3    Nghiem, M.4    Sasaki, T.5    De La Pompa, J.L.6
  • 61
    • 0038433303 scopus 로고    scopus 로고
    • JunD mediates survival signalling by the JNK signal transduction pathway
    • Lamb JA, Ventura JJ, Hess P, Flavell RA, Davis RJ (2003) JunD mediates survival signalling by the JNK signal transduction pathway. Mol. Cell 11, 1479 1489.
    • (2003) Mol. Cell , vol.11 , pp. 1479-1489
    • Lamb, J.A.1    Ventura, J.J.2    Hess, P.3    Flavell, R.A.4    Davis, R.J.5
  • 62
    • 0037418238 scopus 로고    scopus 로고
    • JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
    • Lei K, Davis RJ (2003) JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc. Natl. Acad. Sci. USA 100, 2432 2437.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2432-2437
    • Lei, K.1    Davis, R.J.2
  • 63
    • 0037174934 scopus 로고    scopus 로고
    • JNK phosphorylation and activation of BAD couples the stress activated signalling pathway to the cell death machinery
    • Donovan N, Becker EB, Konishi Y, Bonni A (2002) JNK phosphorylation and activation of BAD couples the stress activated signalling pathway to the cell death machinery. J. Biol. Chem. 277, 40944 40949.
    • (2002) J. Biol. Chem. , vol.277 , pp. 40944-40949
    • Donovan, N.1    Becker, E.B.2    Konishi, Y.3    Bonni, A.4
  • 64
    • 0033499801 scopus 로고    scopus 로고
    • Bcl2 is phosphorylated and inactivated by an ASK1/JUN N-terminal kinase pathway normally activated at G2/M
    • Yamamoto K, Ichijo H, Korsmeyer SJ (1999) Bcl2 is phosphorylated and inactivated by an ASK1/JUN N-terminal kinase pathway normally activated at G2/M. Mol. Cell. Biol. 19, 8469 8478.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 8469-8478
    • Yamamoto, K.1    Ichijo, H.2    Korsmeyer, S.J.3
  • 65
    • 0037434841 scopus 로고    scopus 로고
    • Identification of a novel Bcl-xL phosphorylation site regulating the sensitivity of taxol- or 2-methoxyestradiol induced apoptosis
    • Basu A, Haldar S (2002) Identification of a novel Bcl-xL phosphorylation site regulating the sensitivity of taxol- or 2-methoxyestradiol induced apoptosis. FEBS Lett. 538, 41 47.
    • (2002) FEBS Lett. , vol.538 , pp. 41-47
    • Basu, A.1    Haldar, S.2
  • 66
    • 0036269755 scopus 로고    scopus 로고
    • The Bax subfamily of Bcl2 related proteins is essential for apoptotic signal transduction by JNK
    • Lei K, Nimnual A, Zong WX, Kennedy NJ, Flavell RA, Thompson CB et al. (2002) The Bax subfamily of Bcl2 related proteins is essential for apoptotic signal transduction by JNK. Mol. Cell. Biol. 22, 4929 4942.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4929-4942
    • Lei, K.1    Nimnual, A.2    Zong, W.X.3    Kennedy, N.J.4    Flavell, R.A.5    Thompson, C.B.6
  • 67
    • 0038068111 scopus 로고    scopus 로고
    • The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells
    • Haefliger JA, Tawadros T, Meylan L, Gurun SL, Roehrich ME, Martin D et al. (2003) The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells. J. Cell Sci. 116, 1463 1469.
    • (2003) J. Cell Sci. , vol.116 , pp. 1463-1469
    • Haefliger, J.A.1    Tawadros, T.2    Meylan, L.3    Gurun, S.L.4    Roehrich, M.E.5    Martin, D.6
  • 68
    • 12444335255 scopus 로고    scopus 로고
    • The JNK binding domain of islet brain 1 inhibits IL-1 induced JNK activity and apoptosis but not the transcription of key proapoptotic or protective genes in insulin secreting cell lines
    • Nikulina MA, Sandhu N, Shamim Z, Andersen NA, Oberson A, Dupraz P et al. (2003) The JNK binding domain of islet brain 1 inhibits IL-1 induced JNK activity and apoptosis but not the transcription of key proapoptotic or protective genes in insulin secreting cell lines. Cytokine 24, 13 24.
    • (2003) Cytokine , vol.24 , pp. 13-24
    • Nikulina, M.A.1    Sandhu, N.2    Shamim, Z.3    Andersen, N.A.4    Oberson, A.5    Dupraz, P.6
  • 69
    • 0141866863 scopus 로고    scopus 로고
    • Variations in IB1/JIP1 expression regulate susceptibility of beta cells to cytokine induced apoptosis irrespective of c-jun Nh2 terminal kinase signalling
    • Ling Z, van de Casteele M, Dong J, Helmberg H, Haeflinger JA, Waeber G et al. (2003) Variations in IB1/JIP1 expression regulate susceptibility of beta cells to cytokine induced apoptosis irrespective of c-jun Nh2 terminal kinase signalling. Diabetes 52, 2497 2502.
    • (2003) Diabetes , vol.52 , pp. 2497-2502
    • Ling, Z.1    Van De Casteele, M.2    Dong, J.3    Helmberg, H.4    Haeflinger, J.A.5    Waeber, G.6
  • 70
    • 0037439170 scopus 로고    scopus 로고
    • POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis
    • Xu Z, Kukekov NV, Greene LA (2003) POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis. EMBO J. 22, 252 261.
    • (2003) EMBO J. , vol.22 , pp. 252-261
    • Xu, Z.1    Kukekov, N.V.2    Greene, L.A.3
  • 71
    • 0033118607 scopus 로고    scopus 로고
    • The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development
    • Kuan CY, Yang DD, Samanta Roy DR, Davis RJ, Rakic P, Flavell RA (1999) The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development. Neuron 22, 667 676.
    • (1999) Neuron , vol.22 , pp. 667-676
    • Kuan, C.Y.1    Yang, D.D.2    Samanta Roy, D.R.3    Davis, R.J.4    Rakic, P.5    Flavell, R.A.6
  • 74
    • 0141593385 scopus 로고    scopus 로고
    • Repression of Phospho-JNK and infarct volume in ischemic brain of JIP1-deficient mice
    • Im J-Y, Lee K-W, Kim MH, Lee SH, Ha H-Y, Cho I-H et al. (2003) Repression of Phospho-JNK and infarct volume in ischemic brain of JIP1-deficient mice. J. Neurosci. Res. 74, 326 332.
    • (2003) J. Neurosci. Res. , vol.74 , pp. 326-332
    • Im, J.-Y.1    Lee, K.-W.2    Kim, M.H.3    Lee, S.H.4    Ha, H.-Y.5    Cho, I.-H.6
  • 75
    • 0038345695 scopus 로고    scopus 로고
    • Increased vulnerability of kainic acid-induced epileptic seizures in mice underexpressing the scaffold protein Islet-Brain 1/JIP-1
    • Magara F, Haefliger J-A, Thompson N, Riederer B, Welker E, Nicod P et al. (2003) Increased vulnerability of kainic acid-induced epileptic seizures in mice underexpressing the scaffold protein Islet-Brain 1/JIP-1. Eur. J. Neurosci. 17, 2602 2610.
    • (2003) Eur. J. Neurosci. , vol.17 , pp. 2602-2610
    • Magara, F.1    Haefliger, J.-A.2    Thompson, N.3    Riederer, B.4    Welker, E.5    Nicod, P.6
  • 77
    • 9644296032 scopus 로고    scopus 로고
    • The exon guidance defect of the telencephalic commissures of the JSAP1-deficient brain was partially rescued by the transgenic expression of JIP1
    • Ha H-Y, Cho I-H, Lee K-W, Lee K-W, Song J-Y, Kim K-S et al. (2005) The exon guidance defect of the telencephalic commissures of the JSAP1-deficient brain was partially rescued by the transgenic expression of JIP1. Dev. Biol. 277, 184 199.
    • (2005) Dev. Biol. , vol.277 , pp. 184-199
    • Ha, H.-Y.1    Cho, I.-H.2    Lee, K.-W.3    Lee, K.-W.4    Song, J.-Y.5    Kim, K.-S.6
  • 78
    • 36148956159 scopus 로고    scopus 로고
    • Neural-specific ablation of the scaffold protein JSAP1 in mice causes neonatal death
    • Iwanaga A, Sato T, Sugihara K, Hirao A, Takakura N, Okamoto H et al. (2007) Neural-specific ablation of the scaffold protein JSAP1 in mice causes neonatal death. Neurosci. Lett. 429, 43 48.
    • (2007) Neurosci. Lett. , vol.429 , pp. 43-48
    • Iwanaga, A.1    Sato, T.2    Sugihara, K.3    Hirao, A.4    Takakura, N.5    Okamoto, H.6
  • 80
    • 0034705227 scopus 로고    scopus 로고
    • Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signalling and reduce its threshold properties
    • Levchenko A, Bruck J, Sternberg PW (2000) Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signalling and reduce its threshold properties. Proc. Natl. Acad. Sci. USA 97, 5818 5823.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5818-5823
    • Levchenko, A.1    Bruck, J.2    Sternberg, P.W.3
  • 81
    • 34548059483 scopus 로고    scopus 로고
    • Scaffold proteins confer diverse regulatory properties to protein kinase cascades
    • Locasale JW, Shaw AS, Chakraborty AK (2007) Scaffold proteins confer diverse regulatory properties to protein kinase cascades. Proc. Natl. Acad. Sci. USA 104, 13307 13312.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 13307-13312
    • Locasale, J.W.1    Shaw, A.S.2    Chakraborty, A.K.3
  • 82
    • 46249102993 scopus 로고    scopus 로고
    • Regulations of signal duration and the statistical dynamics of kinase activation by scaffold proteins
    • Locasale JW, Chakraborty AK (2008) Regulations of signal duration and the statistical dynamics of kinase activation by scaffold proteins. PLoS Comput. Biol. 4, e10000099.
    • (2008) PLoS Comput. Biol. , vol.4 , pp. 10000099
    • Locasale, J.W.1    Chakraborty, A.K.2
  • 83
  • 84
    • 0036899420 scopus 로고    scopus 로고
    • Localisation of the MP-1/MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction
    • Teis D, Wunderlich W, Huber LA (2002) Localisation of the MP-1/MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction. Dev. Cell 3, 803 814.
    • (2002) Dev. Cell , vol.3 , pp. 803-814
    • Teis, D.1    Wunderlich, W.2    Huber, L.A.3
  • 85
    • 0041843750 scopus 로고    scopus 로고
    • An integrated model of epidermal growth factor receptor trafficking and signal transduction
    • Resat H, Ewald JA, Dixon DA, Wiley HS (2003) An integrated model of epidermal growth factor receptor trafficking and signal transduction. Biophys. J. 85, 730 743.
    • (2003) Biophys. J. , vol.85 , pp. 730-743
    • Resat, H.1    Ewald, J.A.2    Dixon, D.A.3    Wiley, H.S.4
  • 86
    • 0036212767 scopus 로고    scopus 로고
    • Computational modelling of the dynamics of the MAP kinase cascade activated by surface and internalised EGF-receptors
    • Schoeberl B, Eichler-Jonsson C, Giles ED, Muller G (2003) Computational modelling of the dynamics of the MAP kinase cascade activated by surface and internalised EGF-receptors. Nat. Biotechnol. 20, 370 375.
    • (2003) Nat. Biotechnol. , vol.20 , pp. 370-375
    • Schoeberl, B.1    Eichler-Jonsson, C.2    Giles, E.D.3    Muller, G.4
  • 88
    • 45749097781 scopus 로고    scopus 로고
    • Modulation of interleukin 1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein
    • Blanco S, Sanz-Garcia M, Santos CR, Lazo PA (2008) Modulation of interleukin 1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein. PLoS One 3, e1660.
    • (2008) PLoS One , vol.3 , pp. 1660
    • Blanco, S.1    Sanz-Garcia, M.2    Santos, C.R.3    Lazo, P.A.4
  • 90
    • 0346220278 scopus 로고    scopus 로고
    • Akt2 negatively regulates assembly of the POSH-MLK-JNK signalling complex
    • Figueroa C, Tarras S, Taylor J, Vojtek AB (2003) Akt2 negatively regulates assembly of the POSH-MLK-JNK signalling complex. J. Biol. Chem. 278, 47922 47927.
    • (2003) J. Biol. Chem. , vol.278 , pp. 47922-47927
    • Figueroa, C.1    Tarras, S.2    Taylor, J.3    Vojtek, A.B.4
  • 91
    • 0042030924 scopus 로고    scopus 로고
    • JNK-interacting protein 1 promotes Akt1 activation
    • Kim AH, Sasaki T, Chao MV (2003) JNK-interacting protein 1 promotes Akt1 activation. J. Biol. Chem. 278, 29830 29836.
    • (2003) J. Biol. Chem. , vol.278 , pp. 29830-29836
    • Kim, A.H.1    Sasaki, T.2    Chao, M.V.3
  • 92
    • 22244445193 scopus 로고    scopus 로고
    • Dissociation of Akt1 from its negative regulator JIP-1 is mediated through the ASK1-MEK-JNK signal transduction pathway during metabolic oxidative stress. A negative feedback loop
    • Song JJ, Lee YJ (2005) Dissociation of Akt1 from its negative regulator JIP-1 is mediated through the ASK1-MEK-JNK signal transduction pathway during metabolic oxidative stress. A negative feedback loop. J. Cell Biol. 170, 61 72.
    • (2005) J. Cell Biol. , vol.170 , pp. 61-72
    • Song, J.J.1    Lee, Y.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.