EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells

Biological Chemistry

Volumn 390, Issue 12, 2009, Pages 1293-1302

  Camaj, Peter ^a   Seeliger, Hendrik ^a   Ischenko, Ivan ^a   Krebs, Stefan ^b   Blum, Helmut ^b   De Toni, Enrico N ^a   Faktorova, Dagmar ^c   Jauch, Karl Walter ^a   Bruns, Christiane J ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF ILINA   (Slovakia)

Author keywords

Downstream signaling; EFEMP1; EGF receptor (EGFR); Epidermal growth factor (EGF); Phosphorylation

Indexed keywords

4 (3 BROMOANILINO) 6,7 DIMETHOXYQUINAZOLINE; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN; PROTEIN EFEMP1; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHOSPHORYLATION; BINDING COMPETITION; BINDING SITE; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PANCREAS CARCINOMA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; TUMOR GROWTH;

AMINO ACID SEQUENCE; CELL LINE, TUMOR; EXTRACELLULAR MATRIX PROTEINS; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PHYLOGENY; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SEQUENCE ALIGNMENT;

EID: 72949110623     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2009.140     Document Type: Article

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