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Volumn 27, Issue 6 A, 2007, Pages 3713-3721

New approach to cancer therapy: Heparin binding-epidermal growth factor-like growth factor as a novel targeting molecule

Author keywords

HB EGF; Ovarian cancer; Review; Target; Therapy

Indexed keywords

ANTINEOPLASTIC AGENT; CROSS REACTING MATERIAL 197; CROSSREACTING MATERIAL 197; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; PACLITAXEL; UNCLASSIFIED DRUG;

EID: 35348993675     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (30)

References (55)
  • 1
    • 0031936410 scopus 로고    scopus 로고
    • Specificity within the EGF family/ErbB receptor family signaling network
    • Riese DJ II and Stern DF: Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 20: 41-48, 1998.
    • (1998) Bioessays , vol.20 , pp. 41-48
    • Riese II, D.J.1    Stern, D.F.2
  • 3
    • 9444287030 scopus 로고    scopus 로고
    • Common and distinct elements in cellular signaling via EGF and FGF receptors
    • Schlessinger J: Common and distinct elements in cellular signaling via EGF and FGF receptors. Science 306: 1506-1507, 2004.
    • (2004) Science , vol.306 , pp. 1506-1507
    • Schlessinger, J.1
  • 5
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon DS, Brandt R, Ciardiello F and Normanno N: Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 19: 183-232, 1995.
    • (1995) Crit Rev Oncol Hematol , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3    Normanno, N.4
  • 6
    • 1642421130 scopus 로고    scopus 로고
    • Target-based agents against ErbB receptors and their ligands: A novel approach to cancer treatment
    • Normanno N, Bianco C, De Luca A, Maiello MR and Salomon DS: Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment. Endocr Relat Cancer 10: 1-21, 2003.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 1-21
    • Normanno, N.1    Bianco, C.2    De Luca, A.3    Maiello, M.R.4    Salomon, D.S.5
  • 7
    • 17844372539 scopus 로고    scopus 로고
    • Critical update and emerging trends in epidermal growth factor receptor targeting in cancer
    • Baselga J and Arteaga CL: Critical update and emerging trends in epidermal growth factor receptor targeting in cancer. J Clin Oncol 23: 2445-2449, 2005.
    • (2005) J Clin Oncol , vol.23 , pp. 2445-2449
    • Baselga, J.1    Arteaga, C.L.2
  • 8
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
    • Roberts PJ and Der CJ: Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 26: 3291-3310, 2007.
    • (2007) Oncogene , vol.26 , pp. 3291-3310
    • Roberts, P.J.1    Der, C.J.2
  • 9
    • 31744445943 scopus 로고    scopus 로고
    • The effects of EGF-receptor density on multiscale tumor growth patterns
    • Athale CA and Deisboeck TS: The effects of EGF-receptor density on multiscale tumor growth patterns. J Theor Biol 238: 771-779, 2006.
    • (2006) J Theor Biol , vol.238 , pp. 771-779
    • Athale, C.A.1    Deisboeck, T.S.2
  • 11
    • 0036296013 scopus 로고    scopus 로고
    • TGF-alpha-driven tumor growth is inhibited by an EGF receptor tyrosine kinase inhibitor
    • El-Obeid A, Hesselager G, Westermark B and Nister M: TGF-alpha-driven tumor growth is inhibited by an EGF receptor tyrosine kinase inhibitor. Biochem Biophys Res Commun 290: 349-358, 2002.
    • (2002) Biochem Biophys Res Commun , vol.290 , pp. 349-358
    • El-Obeid, A.1    Hesselager, G.2    Westermark, B.3    Nister, M.4
  • 12
    • 0019320348 scopus 로고
    • Autocrine secretion and malignant transformation of cells
    • Sporn MB and Todaro GJ: Autocrine secretion and malignant transformation of cells. N Engl J Med 303: 878-880, 1980.
    • (1980) N Engl J Med , vol.303 , pp. 878-880
    • Sporn, M.B.1    Todaro, G.J.2
  • 13
    • 0035881981 scopus 로고    scopus 로고
    • A subclass of HER1 ligands are prognostic markers for survival in bladder cancer patients
    • Thogersen VB, Sorensen BS, Poulsen SS, Orntoft TF, Wolf H and Nexo E: A subclass of HER1 ligands are prognostic markers for survival in bladder cancer patients. Cancer Res 61: 6227-6233, 2001.
    • (2001) Cancer Res , vol.61 , pp. 6227-6233
    • Thogersen, V.B.1    Sorensen, B.S.2    Poulsen, S.S.3    Orntoft, T.F.4    Wolf, H.5    Nexo, E.6
  • 15
    • 0025904265 scopus 로고
    • A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF
    • Higashiyama S, Abraham JA, Miller J, Fiddes JC and Klagsbrun M: A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science 251: 936-939, 1991.
    • (1991) Science , vol.251 , pp. 936-939
    • Higashiyama, S.1    Abraham, J.A.2    Miller, J.3    Fiddes, J.C.4    Klagsbrun, M.5
  • 16
    • 0037224740 scopus 로고    scopus 로고
    • The ADAMs family of metalloproteases: Multidomain proteins with multiple functions
    • Seals DF and Courtneidge SA: The ADAMs family of metalloproteases: multidomain proteins with multiple functions. Genes Dev 17: 7-30, 2003.
    • (2003) Genes Dev , vol.17 , pp. 7-30
    • Seals, D.F.1    Courtneidge, S.A.2
  • 19
    • 0028284810 scopus 로고
    • Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which upregulates functional receptors and diphtheria toxin sensitivity
    • Iwamoto R, Higashiyama S, Mitamura T, Taniguchi N, Klagsbrun M and Mekada E: Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which upregulates functional receptors and diphtheria toxin sensitivity. EMBO J 13: 2322-2330, 1994.
    • (1994) EMBO J , vol.13 , pp. 2322-2330
    • Iwamoto, R.1    Higashiyama, S.2    Mitamura, T.3    Taniguchi, N.4    Klagsbrun, M.5    Mekada, E.6
  • 20
    • 0028999004 scopus 로고
    • Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites
    • Nakamura K, Iwamoto R and Mekada E: Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites. J Cell Biol 129: 1691-1705, 1995.
    • (1995) J Cell Biol , vol.129 , pp. 1691-1705
    • Nakamura, K.1    Iwamoto, R.2    Mekada, E.3
  • 21
    • 0028963636 scopus 로고
    • The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor
    • Higashiyama S, Iwamoto R, Goishi K, Raab G, Taniguchi N, Klagsbrun M and Mekada E: The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor. J Cell Biol 128: 929-938, 1995.
    • (1995) J Cell Biol , vol.128 , pp. 929-938
    • Higashiyama, S.1    Iwamoto, R.2    Goishi, K.3    Raab, G.4    Taniguchi, N.5    Klagsbrun, M.6    Mekada, E.7
  • 22
    • 0242425875 scopus 로고    scopus 로고
    • Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF
    • Nanba D, Mammoto A, Hashimoto K and Higashiyama S: Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF. J Cell Biol 163: 489-502, 2003.
    • (2003) J Cell Biol , vol.163 , pp. 489-502
    • Nanba, D.1    Mammoto, A.2    Hashimoto, K.3    Higashiyama, S.4
  • 23
    • 0035839518 scopus 로고    scopus 로고
    • BAG-1 is a novel cytoplasmic binding partner of the membrane form of heparin-binding EGF-like growth factor: A unique role for proHB-EGF in cell survival regulation
    • Lin J, Hutchinson L, Gaston SM, Raab G and Freeman MR: BAG-1 is a novel cytoplasmic binding partner of the membrane form of heparin-binding EGF-like growth factor: a unique role for proHB-EGF in cell survival regulation. J Biol Chem 276: 30127-30132, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 30127-30132
    • Lin, J.1    Hutchinson, L.2    Gaston, S.M.3    Raab, G.4    Freeman, M.R.5
  • 24
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity
    • Takayama S, Sato T, Krajewski S, Kochel K, Irie S, Millan JA and Reed JC: Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity. Cell 80: 279-284, 1995.
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3    Kochel, K.4    Irie, S.5    Millan, J.A.6    Reed, J.C.7
  • 25
    • 0037071399 scopus 로고    scopus 로고
    • Tumor suppressor genes in normal and malignant hematopoiesis
    • Krug U, Ganser A and Koeffler HP: Tumor suppressor genes in normal and malignant hematopoiesis. Oncogene 21: 3475-3495, 2002.
    • (2002) Oncogene , vol.21 , pp. 3475-3495
    • Krug, U.1    Ganser, A.2    Koeffler, H.P.3
  • 26
    • 0037507267 scopus 로고    scopus 로고
    • Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling
    • Jackson LF, Qiu TH, Sunnarborg SW, Chang A, Zhang C, Patterson C and Lee DC: Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling. EMBO J 22: 2704-2716, 2003.
    • (2003) EMBO J , vol.22 , pp. 2704-2716
    • Jackson, L.F.1    Qiu, T.H.2    Sunnarborg, S.W.3    Chang, A.4    Zhang, C.5    Patterson, C.6    Lee, D.C.7
  • 28
    • 0032795261 scopus 로고    scopus 로고
    • Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development
    • Luetteke NC, Qiu TH, Fenton SE, Troyer KL, Riedel RF, Chang A and Lee DC: Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development. Development 126: 2739-2750, 1999.
    • (1999) Development , vol.126 , pp. 2739-2750
    • Luetteke, N.C.1    Qiu, T.H.2    Fenton, S.E.3    Troyer, K.L.4    Riedel, R.F.5    Chang, A.6    Lee, D.C.7
  • 30
    • 33645540607 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor as a novel targeting molecule for cancer therapy
    • Miyamoto S, Yagi H, Yotsumoto F, Kawarabayashi T and Mekada E: Heparin-binding epidermal growth factor-like growth factor as a novel targeting molecule for cancer therapy. Cancer Sci 97: 341-347, 2006.
    • (2006) Cancer Sci , vol.97 , pp. 341-347
    • Miyamoto, S.1    Yagi, H.2    Yotsumoto, F.3    Kawarabayashi, T.4    Mekada, E.5
  • 31
    • 0023860289 scopus 로고
    • A putative new growth factor in ascetic fluid from ovarian cancer patients: Identification, characterization, and mechanism of action
    • Mills GB, May C, McGill M, Roifman CM and Mellers A: A putative new growth factor in ascetic fluid from ovarian cancer patients: identification, characterization, and mechanism of action. Cancer Res 48: 1066-1071, 1988.
    • (1988) Cancer Res , vol.48 , pp. 1066-1071
    • Mills, G.B.1    May, C.2    McGill, M.3    Roifman, C.M.4    Mellers, A.5
  • 33
    • 27644466636 scopus 로고    scopus 로고
    • Clinical significance of heparin-binding EGF (epidermal growth factor)-like growth factor and ADAM (a disintegrin and metalloprotease) 17 expression in human ovarian cancer
    • Tanaka Y, Miyamoto S, Suzuki SO, Oki E, Yagi H, Sonoda K, Yamazaki A, Mizushima H, Maehara Y, Mekada E and Nakano H: Clinical significance of heparin-binding EGF (epidermal growth factor)-like growth factor and ADAM (a disintegrin and metalloprotease) 17 expression in human ovarian cancer. Clin Cancer Res 11: 4783-4792, 2005.
    • (2005) Clin Cancer Res , vol.11 , pp. 4783-4792
    • Tanaka, Y.1    Miyamoto, S.2    Suzuki, S.O.3    Oki, E.4    Yagi, H.5    Sonoda, K.6    Yamazaki, A.7    Mizushima, H.8    Maehara, Y.9    Mekada, E.10    Nakano, H.11
  • 34
    • 0027619786 scopus 로고
    • Taxol dose intensification and its clinical implications
    • Sarosy G and Reed E: Taxol dose intensification and its clinical implications. J Natl Med Assoc 85: 427-431, 1993.
    • (1993) J Natl Med Assoc , vol.85 , pp. 427-431
    • Sarosy, G.1    Reed, E.2
  • 35
    • 0028303080 scopus 로고
    • Update on the antitumor activity of paclitaxel in clinical trials
    • Rowinsky EK: Update on the antitumor activity of paclitaxel in clinical trials. Ann Pharmacother 28: S18-22, 1994.
    • (1994) Ann Pharmacother , vol.28
    • Rowinsky, E.K.1
  • 36
    • 0028860250 scopus 로고
    • Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity
    • Mitamura T, Higashiyama S, Taniguchi N, Klgasbrun M and Mekada E: Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity. J Biol Chem 270: 1015-1019, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 1015-1019
    • Mitamura, T.1    Higashiyama, S.2    Taniguchi, N.3    Klgasbrun, M.4    Mekada, E.5
  • 39
    • 0029885411 scopus 로고    scopus 로고
    • Coexpression of heparin-binding EGF-like growth factor and related peptides in human gastric carcinoma
    • Naef M, Yokoyama M, Friess H, Buchler MW and Korc M: Coexpression of heparin-binding EGF-like growth factor and related peptides in human gastric carcinoma. Int J Cancer 66: 315-321, 1996.
    • (1996) Int J Cancer , vol.66 , pp. 315-321
    • Naef, M.1    Yokoyama, M.2    Friess, H.3    Buchler, M.W.4    Korc, M.5
  • 40
    • 0035407354 scopus 로고    scopus 로고
    • Expression of heparin binding epidermal growth factor-like growth factor in hepatocellular carcinoma: An immunohistochemical study
    • 903-907
    • Ito Y, Takeda T, Higashiyama S, Sakon M, Wakasa KI, Tsujimoto M, Monden M and Matsuura N: Expression of heparin binding epidermal growth factor-like growth factor in hepatocellular carcinoma: an immunohistochemical study. Oncology Reports 8: 903-907, 2001.
    • (2001) Oncology Reports , vol.8
    • Ito, Y.1    Takeda, T.2    Higashiyama, S.3    Sakon, M.4    Wakasa, K.I.5    Tsujimoto, M.6    Monden, M.7    Matsuura, N.8
  • 41
    • 0034829649 scopus 로고    scopus 로고
    • Expression of heparin-binding epidermal growth factor-like growth factor in pancreatic adenocarcinoma
    • Ito Y, Higashiyama S, Takeda T, Yamamoto Y, Wakasa KI and Matsuura N: Expression of heparin-binding epidermal growth factor-like growth factor in pancreatic adenocarcinoma. Int J Pancreatol 29: 47-52, 2001.
    • (2001) Int J Pancreatol , vol.29 , pp. 47-52
    • Ito, Y.1    Higashiyama, S.2    Takeda, T.3    Yamamoto, Y.4    Wakasa, K.I.5    Matsuura, N.6
  • 43
    • 34047153280 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor is an early response gene to chemotherapy and contributes to chemotherapy resistance
    • Wang F, Liu R, Lee SW, Sloss CM, Couget J and Cusack JC: Heparin-binding EGF-like growth factor is an early response gene to chemotherapy and contributes to chemotherapy resistance. Oncogene 26: 2006-2016, 2007.
    • (2007) Oncogene , vol.26 , pp. 2006-2016
    • Wang, F.1    Liu, R.2    Lee, S.W.3    Sloss, C.M.4    Couget, J.5    Cusack, J.C.6
  • 44
    • 27944467499 scopus 로고    scopus 로고
    • Resistance to epidermal growth factor receptor-targeted therapy
    • Morgillo F and Lee HY: Resistance to epidermal growth factor receptor-targeted therapy. Drug Resistance Updates 8: 298-310, 2005.
    • (2005) Drug Resistance Updates , vol.8 , pp. 298-310
    • Morgillo, F.1    Lee, H.Y.2
  • 47
    • 4143066760 scopus 로고    scopus 로고
    • Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
    • Sordella R, Bell DW, Haber DA and Settleman J: Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science 305: 1163-1167, 2004.
    • (2004) Science , vol.305 , pp. 1163-1167
    • Sordella, R.1    Bell, D.W.2    Haber, D.A.3    Settleman, J.4
  • 48
    • 17144395523 scopus 로고    scopus 로고
    • Inhibition of mutant EGF receptors by gefitinib: Targeting an achilles' heel of lung cancer
    • Settleman J: Inhibition of mutant EGF receptors by gefitinib: targeting an achilles' heel of lung cancer. Cell Cycle 3: 1496-1497, 2004.
    • (2004) Cell Cycle , vol.3 , pp. 1496-1497
    • Settleman, J.1
  • 49
    • 28844509531 scopus 로고    scopus 로고
    • K-ras as a target for cancer therapy
    • Friday BB and Adjei AA: K-ras as a target for cancer therapy. Biochem Biophys Acta 1756: 127-144, 2005.
    • (2005) Biochem Biophys Acta , vol.1756 , pp. 127-144
    • Friday, B.B.1    Adjei, A.A.2
  • 50
    • 0030762433 scopus 로고    scopus 로고
    • A raf-independent epidermal growth factor receptor autocrine loop is necessary for ras transformation of rat intestinal epithelial cells
    • Gangarosa M, Sizemore N, Graves-Deal R, Oldham SM, Der CJ and Coffey RJ: A raf-independent epidermal growth factor receptor autocrine loop is necessary for ras transformation of rat intestinal epithelial cells. J Biol Chem 272: 18926-18931, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 18926-18931
    • Gangarosa, M.1    Sizemore, N.2    Graves-Deal, R.3    Oldham, S.M.4    Der, C.J.5    Coffey, R.J.6
  • 51
    • 0029814271 scopus 로고    scopus 로고
    • A hierarchial network of interreceptor interactions determines signal transduction by neu differentiation factor/neuregulin and epidermal growth factor
    • Tzahar E, Waterman H, Chen X, Levkowitz G, Karunagaran D, Lavi S, Ratzkin BJ and Yagen Y: A hierarchial network of interreceptor interactions determines signal transduction by neu differentiation factor/neuregulin and epidermal growth factor. Mol Cell Biol 16: 5276-5287, 1996.
    • (1996) Mol Cell Biol , vol.16 , pp. 5276-5287
    • Tzahar, E.1    Waterman, H.2    Chen, X.3    Levkowitz, G.4    Karunagaran, D.5    Lavi, S.6    Ratzkin, B.J.7    Yagen, Y.8
  • 53
    • 0035915421 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin)
    • Lu Y, Zi X, Zhao Y, Mascarrenhas D and Pollak M: Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). J Natl Cancer Inst 93: 1852-1857, 2001.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1852-1857
    • Lu, Y.1    Zi, X.2    Zhao, Y.3    Mascarrenhas, D.4    Pollak, M.5
  • 55
    • 0034698096 scopus 로고    scopus 로고
    • Transactivation of the EGF receptor mediates IGF-I-stimulated shc phosphorylation and ERK1/2 activation in COS-7 cells
    • Roudabush FL, Pierce KL, Maudsley S, Khan KD and Luttrell LM: Transactivation of the EGF receptor mediates IGF-I-stimulated shc phosphorylation and ERK1/2 activation in COS-7 cells. J Biol Chem 275: 22583-22589, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 22583-22589
    • Roudabush, F.L.1    Pierce, K.L.2    Maudsley, S.3    Khan, K.D.4    Luttrell, L.M.5


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