-
1
-
-
0037477605
-
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice
-
Ansari, M. J., A. D. Salama, T. Chitnis, R. N. Smith, H. Yagita, H. Akiba, T. Yamazaki, M. Azuma, H. Iwai, S. J. Khoury, H. Auchincloss, Jr., and M. H. Sayegh. 2003. The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. J. Exp. Med. 198:63-69.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 63-69
-
-
Ansari, M.J.1
Salama, A.D.2
Chitnis, T.3
Smith, R.N.4
Yagita, H.5
Akiba, H.6
Yamazaki, T.7
Azuma, M.8
Iwai, H.9
Khoury, S.J.10
Auchincloss Jr., H.11
Sayegh, M.H.12
-
2
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
Barber, D. L., E. J. Wherry, D. Masopust, B. Zhu, J. P. Allison, A. H. Sharpe, G. J. Freeman, and R. Ahmed. 2006. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 439:682-687.
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
3
-
-
0031015164
-
Gp120, a human immunodeficiency virus-1 coat protein, augments excitotoxic hippocampal injury in perinatal rats
-
Barks, J. D., X. H. Liu, R. Sun, and F. S. Silverstein. 1997. gp120, a human immunodeficiency virus-1 coat protein, augments excitotoxic hippocampal injury in perinatal rats. Neuroscience 76:397-409.
-
(1997)
Neuroscience
, vol.76
, pp. 397-409
-
-
Barks, J.D.1
Liu, X.H.2
Sun, R.3
Silverstein, F.S.4
-
4
-
-
0037561928
-
Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells
-
Brenchley, J. M., N. J. Karandikar, M. R. Betts, D. R. Ambrozak, B. J. Hill, L. E. Crotty, J. P. Casazza, J. Kuruppu, S. A. Migueles, M. Connors, M. Roederer, D. C. Douek, and R. A. Koup. 2003. Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells. Blood 101:2711-2720.
-
(2003)
Blood
, vol.101
, pp. 2711-2720
-
-
Brenchley, J.M.1
Karandikar, N.J.2
Betts, M.R.3
Ambrozak, D.R.4
Hill, B.J.5
Crotty, L.E.6
Casazza, J.P.7
Kuruppu, J.8
Migueles, S.A.9
Connors, M.10
Roederer, M.11
Douek, D.C.12
Koup, R.A.13
-
6
-
-
0026661095
-
Early viral brain invasion in iatrogenic human immunodeficiency virus infection
-
Davis, L. E., B. L. Hjelle, V. E. Miller, D. L. Palmer, A. L. Llewellyn, T. L. Merlin, S. A. Young, R. G. Mills, W. Wachsman, and C. A. Wiley. 1992. Early viral brain invasion in iatrogenic human immunodeficiency virus infection. Neurology 42:1736-1739.
-
(1992)
Neurology
, vol.42
, pp. 1736-1739
-
-
Davis, L.E.1
Hjelle, B.L.2
Miller, V.E.3
Palmer, D.L.4
Llewellyn, A.L.5
Merlin, T.L.6
Young, S.A.7
Mills, R.G.8
Wachsman, W.9
Wiley, C.A.10
-
7
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
Day, C. L., D. E. Kaufmann, P. Kiepiela, J. A. Brown, E. S. Moodley, S. Reddy, E. W. Mackey, J. D. Miller, A. J. Leslie, C. DePierres, Z. Mncube, J. Duraiswamy, B. Zhu, Q. Eichbaum, M. Altfeld, E. J. Wherry, H. M. Coovadia, P. J. Goulder, P. Klenerman, R. Ahmed, G. J. Freeman, and B. D. Walker. 2006. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443:350-354.
-
(2006)
Nature
, vol.443
, pp. 350-354
-
-
Day, C.L.1
Kaufmann, D.E.2
Kiepiela, P.3
Brown, J.A.4
Moodley, E.S.5
Reddy, S.6
Mackey, E.W.7
Miller, J.D.8
Leslie, A.J.9
DePierres, C.10
Mncube, Z.11
Duraiswamy, J.12
Zhu, B.13
Eichbaum, Q.14
Altfeld, M.15
Wherry, E.J.16
Coovadia, H.M.17
Goulder, P.J.18
Klenerman, P.19
Ahmed, R.20
Freeman, G.J.21
Walker, B.D.22
more..
-
8
-
-
34548637484
-
Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction
-
D'Souza, M., A. P. Fontenot, D. G. Mack, C. Lozupone, S. Dillon, A. Meditz, C. C. Wilson, E. Connick, and B. E. Palmer. 2007. Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction. J. Immunol. 179:1979-1987.
-
(2007)
J. Immunol.
, vol.179
, pp. 1979-1987
-
-
D'Souza, M.1
Fontenot, A.P.2
Mack, D.G.3
Lozupone, C.4
Dillon, S.5
Meditz, A.6
Wilson, C.C.7
Connick, E.8
Palmer, B.E.9
-
9
-
-
45549092692
-
Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques
-
Estes, J. D., S. N. Gordon, M. Zeng, A. M. Chahroudi, R. M. Dunham, S. I. Staprans, C. S. Reilly, G. Silvestri, and A. T. Haase. 2008. Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques. J. Immunol. 180:6798-6807.
-
(2008)
J. Immunol.
, vol.180
, pp. 6798-6807
-
-
Estes, J.D.1
Gordon, S.N.2
Zeng, M.3
Chahroudi, A.M.4
Dunham, R.M.5
Staprans, S.I.6
Reilly, C.S.7
Silvestri, G.8
Haase, A.T.9
-
10
-
-
33749324118
-
Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade
-
Freeman, G. J., E. J. Wherry, R. Ahmed, and A. H. Sharpe. 2006. Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade. J. Exp. Med. 203:2223-2227.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2223-2227
-
-
Freeman, G.J.1
Wherry, E.J.2
Ahmed, R.3
Sharpe, A.H.4
-
11
-
-
0034723366
-
HIV infection and dementia
-
Gartner, S. 2000. HIV infection and dementia. Science 287:602-604.
-
(2000)
Science
, vol.287
, pp. 602-604
-
-
Gartner, S.1
-
13
-
-
0022490175
-
Expression of human immunodeficiency virus antigen (HIV-Ag) in serum and cerebrospinal fluid during acute and chronic infection
-
Goudsmit, J., F. de Wolf, D. A. Paul, L. G. Epstein, J. M. Lange, W. J. Krone, H. Speelman, E. C. Wolters, J. Van der Noordaa, J. M. Oleske, et al. 1986. Expression of human immunodeficiency virus antigen (HIV-Ag) in serum and cerebrospinal fluid during acute and chronic infection. Lancet ii:177-180. (Pubitemid 16059398)
-
(1986)
Lancet
, vol.2
, Issue.8500
, pp. 177-180
-
-
Goudsmit, J.1
De Wolf, F.2
Paul, D.A.3
-
14
-
-
0038143296
-
Immune responses to RNA-virus infections of the CNS
-
Griffin, D. E. 2003. Immune responses to RNA-virus infections of the CNS. Nat. Rev. Immunol. 3:493-502.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 493-502
-
-
Griffin, D.E.1
-
15
-
-
37849016110
-
CD8(+) T cells specific for both persistent and non-persistent viruses display distinct differentiation phenotypes but have similar level of PD-1 expression in healthy Chinese individuals
-
He, X. H., Q. T. Jia, F. Y. Li, M. Saltis, Y. Liu, L. H. Xu, and Q. B. Zha. 2008. CD8(+) T cells specific for both persistent and non-persistent viruses display distinct differentiation phenotypes but have similar level of PD-1 expression in healthy Chinese individuals. Clin. Immunol. 126:222-234.
-
(2008)
Clin. Immunol.
, vol.126
, pp. 222-234
-
-
He, X.H.1
Jia, Q.T.2
Li, F.Y.3
Saltis, M.4
Liu, Y.5
Xu, L.H.6
Zha, Q.B.7
-
16
-
-
0032492918
-
Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4
-
Hesselgesser, J., D. Taub, P. Baskar, M. Greenberg, J. Hoxie, D. L. Kolson, and R. Horuk. 1998. Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4. Curr. Biol. 8:595-598.
-
(1998)
Curr. Biol.
, vol.8
, pp. 595-598
-
-
Hesselgesser, J.1
Taub, D.2
Baskar, P.3
Greenberg, M.4
Hoxie, J.5
Kolson, D.L.6
Horuk, R.7
-
17
-
-
13544259967
-
Prevention of experimental autoimmune encephalomyelitis by transfer of embryonic stem cell-derived dendritic cells expressing myelin oligodendrocyte glycoprotein peptide along with TRAIL or programmed death-1 ligand 1
-
Hirata, S., S. Senju, H. Matsuyoshi, D. Fukuma, Y. Uemura, and Y. Nishimura. 2005. Prevention of experimental autoimmune encephalomyelitis by transfer of embryonic stem cell-derived dendritic cells expressing myelin oligodendrocyte glycoprotein peptide along with TRAIL or programmed death-1 ligand. J. Immunol. 174:1888-1897. (Pubitemid 40223928)
-
(2005)
Journal of Immunology
, vol.174
, Issue.4
, pp. 1888-1897
-
-
Hirata, S.1
Senju, S.2
Matsuyoshi, H.3
Fukuma, D.4
Uemura, Y.5
Nishimura, Y.6
-
18
-
-
47049083508
-
Activation drives PD-1 expression during vaccine-specific proliferation and following lentiviral infection in macaques
-
Hokey, D. A., F. B. Johnson, J. Smith, J. L. Weber, J. Yan, L. Hirao, J. D. Boyer, M. G. Lewis, G. Makedonas, M. R. Betts, and D. B. Weiner. 2008. Activation drives PD-1 expression during vaccine-specific proliferation and following lentiviral infection in macaques. Eur. J. Immunol. 38:1435-1445.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 1435-1445
-
-
Hokey, D.A.1
Johnson, F.B.2
Smith, J.3
Weber, J.L.4
Yan, J.5
Hirao, L.6
Boyer, J.D.7
Lewis, M.G.8
Makedonas, G.9
Betts, M.R.10
Weiner, D.B.11
-
19
-
-
0026775107
-
Detection of a vigorous HIV-1-specific cytotoxic T lymphocyte response in cerebrospinal fluid from infected persons with AIDS dementia complex
-
Jassoy, C., R. P. Johnson, B. A. Navia, J. Worth, and B. D. Walker. 1992. Detection of a vigorous HIV-1-specific cytotoxic T lymphocyte response in cerebrospinal fluid from infected persons with AIDS dementia complex. J. Immunol. 149:3113-3119.
-
(1992)
J. Immunol.
, vol.149
, pp. 3113-3119
-
-
Jassoy, C.1
Johnson, R.P.2
Navia, B.A.3
Worth, J.4
Walker, B.D.5
-
20
-
-
20744441837
-
Association of a PDCD1 polymorphism with renal manifestations in systemic lupus erythematosus
-
DOI 10.1002/art.21058
-
Johansson, M., L. Arlestig, B. Moller, and S. Rantapaa-Dahlqvist. 2005. Association of a PDCD1 polymorphism with renal manifestations in systemic lupus erythematosus. Arthritis Rheum. 52:1665-1669. (Pubitemid 40852873)
-
(2005)
Arthritis and Rheumatism
, vol.52
, Issue.6
, pp. 1665-1669
-
-
Johansson, M.1
Arlestig, L.2
Moller, B.3
Rantapaa-Dahlqvist, S.4
-
21
-
-
42649125225
-
PD-1 and its ligands in tolerance and immunity
-
Keir, M. E., M. J. Butte, G. J. Freeman, and A. H. Sharpe. 2008. PD-1 and its ligands in tolerance and immunity. Annu. Rev. Immunol. 26:677-704.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 677-704
-
-
Keir, M.E.1
Butte, M.J.2
Freeman, G.J.3
Sharpe, A.H.4
-
23
-
-
7244239292
-
Identification of T lymphocytes in simian immunodeficiency virus encephalitis: Distribution of CD8+ T cells in association with central nervous system vessels and virus
-
Kim, W. K., S. Corey, G. Chesney, H. Knight, S. Klumpp, C. Wuthrich, N. Letvin, I. Koralnik, A. Lackner, R. Veasey, and K. Williams. 2004. Identification of T lymphocytes in simian immunodeficiency virus encephalitis: distribution of CD8+ T cells in association with central nervous system vessels and virus. J. Neurovirol. 10:315-325.
-
(2004)
J. Neurovirol.
, vol.10
, pp. 315-325
-
-
Kim, W.K.1
Corey, S.2
Chesney, G.3
Knight, H.4
Klumpp, S.5
Wuthrich, C.6
Letvin, N.7
Koralnik, I.8
Lackner, A.9
Veasey, R.10
Williams, K.11
-
24
-
-
58149191881
-
The common gamma-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands
-
Kinter, A. L., E. J. Godbout, J. P. McNally, I. Sereti, G. A. Roby, M. A. O'Shea, and A. S. Fauci. 2008. The common gamma-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands. J. Immunol. 181:6738-6746.
-
(2008)
J. Immunol.
, vol.181
, pp. 6738-6746
-
-
Kinter, A.L.1
Godbout, E.J.2
McNally, J.P.3
Sereti, I.4
Roby, G.A.5
O'Shea, M.A.6
Fauci, A.S.7
-
25
-
-
21844451620
-
A PD-1 polymorphism is associated with disease progression in multiple sclerosis
-
Kroner, A., M. Mehling, B. Hemmer, P. Rieckmann, K. V. Toyka, M. Maurer, and H. Wiendl. 2005. A PD-1 polymorphism is associated with disease progression in multiple sclerosis. Ann. Neurol. 58:50-57.
-
(2005)
Ann. Neurol.
, vol.58
, pp. 50-57
-
-
Kroner, A.1
Mehling, M.2
Hemmer, B.3
Rieckmann, P.4
Toyka, K.V.5
Maurer, M.6
Wiendl, H.7
-
26
-
-
33749512800
-
+ cells in HIV-infected and uninfected individuals
-
Le Priol, Y., D. Puthier, C. Lecureuil, C. Combadiere, P. Debre, C. Nguyen, and B. Combadiere. 2006. High cytotoxic and specific migratory potencies of senescent CD8+ CD57+ cells in HIV-infected and uninfected individuals. J. Immunol. 177:5145-5154. (Pubitemid 44527586)
-
(2006)
Journal of Immunology
, vol.177
, Issue.8
, pp. 5145-5154
-
-
Le Priol, Y.1
Puthier, D.2
Lecureuil, C.3
Combadiere, C.4
Debre, P.5
Nguyen, C.6
Combadiere, B.7
-
27
-
-
20144378485
-
Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: Implications for immune responses and autoimmunity in the CNS
-
Magnus, T., B. Schreiner, T. Korn, C. Jack, H. Guo, J. Antel, I. Ifergan, L. Chen, F. Bischof, A. Bar-Or, and H. Wiendl. 2005. Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS. J. Neurosci. 25:2537-2546.
-
(2005)
J. Neurosci.
, vol.25
, pp. 2537-2546
-
-
Magnus, T.1
Schreiner, B.2
Korn, T.3
Jack, C.4
Guo, H.5
Antel, J.6
Ifergan, I.7
Chen, L.8
Bischof, F.9
Bar-Or, A.10
Wiendl, H.11
-
28
-
-
34247626328
-
Enrichment and persistence of virus-specific CTL in the brain of simian immunodeficiency virus-infected monkeys is associated with a unique cytokine environment
-
Marcondes, M. C., T. H. Burdo, S. Sopper, S. Huitron-Resendiz, C. Lanigan, D. Watry, C. Flynn, M. Zandonatti, and H. S. Fox. 2007. Enrichment and persistence of virus-specific CTL in the brain of simian immunodeficiency virus-infected monkeys is associated with a unique cytokine environment. J. Immunol. 178:5812-5819.
-
(2007)
J. Immunol.
, vol.178
, pp. 5812-5819
-
-
Marcondes, M.C.1
Burdo, T.H.2
Sopper, S.3
Huitron-Resendiz, S.4
Lanigan, C.5
Watry, D.6
Flynn, C.7
Zandonatti, M.8
Fox, H.S.9
-
29
-
-
0035500652
-
Highly activated CD8(+) T cells in the brain correlate with early central nervous system dysfunction in simian immunodeficiency virus infection
-
Marcondes, M. C., E. M. Burudi, S. Huitron-Resendiz, M. Sanchez-Alavez, D. Watry, M. Zandonatti, S. J. Henriksen, and H. S. Fox. 2001. Highly activated CD8(+) T cells in the brain correlate with early central nervous system dysfunction in simian immunodeficiency virus infection. J. Immunol. 167:5429-5438.
-
(2001)
J. Immunol.
, vol.167
, pp. 5429-5438
-
-
Marcondes, M.C.1
Burudi, E.M.2
Huitron-Resendiz, S.3
Sanchez-Alavez, M.4
Watry, D.5
Zandonatti, M.6
Henriksen, S.J.7
Fox, H.S.8
-
30
-
-
0030068995
-
Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic
-
Nath, A., K. Psooy, C. Martin, B. Knudsen, D. S. Magnuson, N. Haughey, and J. D. Geiger. 1996. Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic. J. Virol. 70:1475-1480. (Pubitemid 26062905)
-
(1996)
Journal of Virology
, vol.70
, Issue.3
, pp. 1475-1480
-
-
Nath, A.1
Psooy, K.2
Martin, C.3
Knudsen, B.4
Magnuson, D.S.K.5
Haughey, N.6
Geiger, J.D.7
-
31
-
-
18144378387
-
T-cell activation and memory phenotypes in cerebrospinal fluid during HIV infection
-
Neuenburg, J. K., T. A. Cho, A. Nilsson, B. M. Bredt, S. J. Hebert, R. M. Grant, and R. W. Price. 2005. T-cell activation and memory phenotypes in cerebrospinal fluid during HIV infection. J. Acquir. Immune Defic. Syndr. 39:16-22.
-
(2005)
J. Acquir. Immune Defic. Syndr.
, vol.39
, pp. 16-22
-
-
Neuenburg, J.K.1
Cho, T.A.2
Nilsson, A.3
Bredt, B.M.4
Hebert, S.J.5
Grant, R.M.6
Price, R.W.7
-
32
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
DOI 10.1016/S1074-7613(00)80089-8
-
Nishimura, H., M. Nose, H. Hiai, N. Minato, and T. Honjo. 1999. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 11:141-151. (Pubitemid 29428807)
-
(1999)
Immunity
, vol.11
, Issue.2
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
33
-
-
49649111913
-
B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: Implications for the lesion pathogenesis of multiple sclerosis
-
Ortler, S., C. Leder, M. Mittelbronn, A. L. Zozulya, P. A. Knolle, L. Chen, A. Kroner, and H. Wiendl. 2008. B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis. Eur. J. Immunol. 38:1734-1744.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 1734-1744
-
-
Ortler, S.1
Leder, C.2
Mittelbronn, M.3
Zozulya, A.L.4
Knolle, P.A.5
Chen, L.6
Kroner, A.7
Wiendl, H.8
-
34
-
-
0035795072
-
Enhanced expression of fractalkine in HIV-1 associated dementia
-
Pereira, C. F., J. Middel, G. Jansen, J. Verhoef, and H. S. Nottet. 2001. Enhanced expression of fractalkine in HIV-1 associated dementia. J. Neuroimmunol. 115:168-175.
-
(2001)
J. Neuroimmunol.
, vol.115
, pp. 168-175
-
-
Pereira, C.F.1
Middel, J.2
Jansen, G.3
Verhoef, J.4
Nottet, H.S.5
-
35
-
-
33749338938
-
PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection
-
Petrovas, C., J. P. Casazza, J. M. Brenchley, D. A. Price, E. Gostick, W. C. Adams, M. L. Precopio, T. Schacker, M. Roederer, D. C. Douek, and R. A. Koup. 2006. PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection. J. Exp. Med. 203:2281-2292.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2281-2292
-
-
Petrovas, C.1
Casazza, J.P.2
Brenchley, J.M.3
Price, D.A.4
Gostick, E.5
Adams, W.C.6
Precopio, M.L.7
Schacker, T.8
Roederer, M.9
Douek, D.C.10
Koup, R.A.11
-
36
-
-
14944360112
-
Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4
-
Probst, H. C., K. McCoy, T. Okazaki, T. Honjo, and M. van den Broek. 2005. Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4. Nat. Immunol. 6:280-286.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 280-286
-
-
Probst, H.C.1
McCoy, K.2
Okazaki, T.3
Honjo, T.4
Van Den Broek, M.5
-
37
-
-
33947407689
-
Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression
-
Radziewicz, H., C. C. Ibegbu, M. L. Fernandez, K. A. Workowski, K. Obideen, M. Wehbi, H. L. Hanson, J. P. Steinberg, D. Masopust, E. J. Wherry, J. D. Altman, B. T. Rouse, G. J. Freeman, R. Ahmed, and A. Grakoui. 2007. Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression. J. Virol. 81:2545-2553.
-
(2007)
J. Virol.
, vol.81
, pp. 2545-2553
-
-
Radziewicz, H.1
Ibegbu, C.C.2
Fernandez, M.L.3
Workowski, K.A.4
Obideen, K.5
Wehbi, M.6
Hanson, H.L.7
Steinberg, J.P.8
Masopust, D.9
Wherry, E.J.10
Altman, J.D.11
Rouse, B.T.12
Freeman, G.J.13
Ahmed, R.14
Grakoui, A.15
-
38
-
-
0023866331
-
Early penetration of the blood-brain-barrier by HIV
-
Resnick, L., J. R. Berger, P. Shapshak, and W. W. Tourtellotte. 1988. Early penetration of the blood-brain-barrier by HIV. Neurology 38:9-14.
-
(1988)
Neurology
, vol.38
, pp. 9-14
-
-
Resnick, L.1
Berger, J.R.2
Shapshak, P.3
Tourtellotte, W.W.4
-
39
-
-
33646851051
-
Host response and dysfunction in the CNS during chronic simian immunodeficiency virus infection
-
Roberts, E. S., S. Huitron-Resendiz, M. A. Taffe, M. C. Marcondes, C. T. Flynn, C. M. Lanigan, J. A. Hammond, S. R. Head, S. J. Henriksen, and H. S. Fox. 2006. Host response and dysfunction in the CNS during chronic simian immunodeficiency virus infection. J. Neurosci. 26:4577-4585.
-
(2006)
J. Neurosci.
, vol.26
, pp. 4577-4585
-
-
Roberts, E.S.1
Huitron-Resendiz, S.2
Taffe, M.A.3
Marcondes, M.C.4
Flynn, C.T.5
Lanigan, C.M.6
Hammond, J.A.7
Head, S.R.8
Henriksen, S.J.9
Fox, H.S.10
-
40
-
-
55249089046
-
+ T cells in cerebrospinal fluid compared to those in blood among antiretroviral therapy-naïve HIV-positive subjects
-
DOI 10.1128/JVI.01190-08
-
Sadagopal, S., S. L. Lorey, L. Barnett, R. Basham, L. Lebo, H. Erdem, K. Haman, M. Avison, K. Waddell, D. W. Haas, and S. A. Kalams. 2008. Enhancement of human immunodeficiency virus (HIV)-specific CD8+ T cells in cerebrospinal fluid compared to those in blood among antiretroviral therapy-naive HIV-positive subjects. J. Virol. 82:10418-10428. (Pubitemid 352691154)
-
(2008)
Journal of Virology
, vol.82
, Issue.21
, pp. 10418-10428
-
-
Sadagopal, S.1
Lorey, S.L.2
Barnett, L.3
Basham, R.4
Lebo, L.5
Erdem, H.6
Haman, K.7
Avison, M.8
Waddell, K.9
Haas, D.W.10
Kalams, S.A.11
-
41
-
-
0037477604
-
Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis
-
Salama, A. D., T. Chitnis, J. Imitola, M. J. Ansari, H. Akiba, F. Tushima, M. Azuma, H. Yagita, M. H. Sayegh, and S. J. Khoury. 2003. Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis. J. Exp. Med. 198:71-78.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 71-78
-
-
Salama, A.D.1
Chitnis, T.2
Imitola, J.3
Ansari, M.J.4
Akiba, H.5
Tushima, F.6
Azuma, M.7
Yagita, H.8
Sayegh, M.H.9
Khoury, S.J.10
-
42
-
-
34648828497
-
PD-1 expression on human CD8 T cells depends on both state of differentiation and activation status
-
DOI 10.1097/QAD.0b013e3282eee548, PII 0000203020071001000002
-
Sauce, D., J. R. Almeida, M. Larsen, L. Haro, B. Autran, G. J. Freeman, and V. Appay. 2007. PD-1 expression on human CD8 T cells depends on both state of differentiation and activation status. AIDS 21:2005-2013. (Pubitemid 47462149)
-
(2007)
AIDS
, vol.21
, Issue.15
, pp. 2005-2013
-
-
Sauce, D.1
Almeida, J.R.2
Larsen, M.3
Haro, L.4
Autran, B.5
Freeman, G.J.6
Appay, V.7
-
43
-
-
34247884612
-
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
-
Sharpe, A. H., E. J. Wherry, R. Ahmed, and G. J. Freeman. 2007. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat. Immunol. 8:239-245.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 239-245
-
-
Sharpe, A.H.1
Wherry, E.J.2
Ahmed, R.3
Freeman, G.J.4
-
44
-
-
0027242269
-
Adhesion molecule expression on cerebrospinal fluid T lymphocytes: Evidence for common recruitment mechanisms in multiple sclerosis, aseptic meningitis, and normal controls
-
Svenningsson, A., G. K. Hansson, O. Andersen, R. Andersson, M. Patarroyo, and S. Stemme. 1993. Adhesion molecule expression on cerebrospinal fluid T lymphocytes: evidence for common recruitment mechanisms in multiple sclerosis, aseptic meningitis, and normal controls. Ann. Neurol. 34:155-161.
-
(1993)
Ann. Neurol.
, vol.34
, pp. 155-161
-
-
Svenningsson, A.1
Hansson, G.K.2
Andersen, O.3
Andersson, R.4
Patarroyo, M.5
Stemme, S.6
-
45
-
-
0034141496
-
Neuronal fractalkine expression in HIV-1 encephalitis: Roles for macrophage recruitment and neuroprotection in the central nervous system
-
Tong, N., S. W. Perry, Q. Zhang, H. J. James, H. Guo, A. Brooks, H. Bal, S. A. Kinnear, S. Fine, L. G. Epstein, D. Dairaghi, T. J. Schall, H. E. Gendelman, S. Dewhurst, L. R. Sharer, and H. A. Gelbard. 2000. Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system. J. Immunol. 164: 1333-1339. (Pubitemid 30067246)
-
(2000)
Journal of Immunology
, vol.164
, Issue.3
, pp. 1333-1339
-
-
Tong, N.1
Perry, S.W.2
Zhang, Q.3
James, H.J.4
Guo, H.5
Brooks, A.6
Bal, H.7
Kinnear, S.A.8
Fine, S.9
Epstein, L.G.10
Dairaghi, D.11
Schall, T.J.12
Gendelman, H.E.13
Dewhurst, S.14
Sharer, L.R.15
Gelbard, H.A.16
-
46
-
-
33749009709
-
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
-
Trautmann, L., L. Janbazian, N. Chomont, E. A. Said, S. Gimmig, B. Bessette, M. R. Boulassel, E. Delwart, H. Sepulveda, R. S. Balderas, J. P. Routy, E. K. Haddad, and R. P. Sekaly. 2006. Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat. Med. 12:1198-1202.
-
(2006)
Nat. Med.
, vol.12
, pp. 1198-1202
-
-
Trautmann, L.1
Janbazian, L.2
Chomont, N.3
Said, E.A.4
Gimmig, S.5
Bessette, B.6
Boulassel, M.R.7
Delwart, E.8
Sepulveda, H.9
Balderas, R.S.10
Routy, J.P.11
Haddad, E.K.12
Sekaly, R.P.13
-
47
-
-
62249172189
-
Enhancing SIV-specific immunity in vivo by PD-1 blockade
-
Velu, V., K. Titanji, B. Zhu, S. Husain, A. Pladevega, L. Lai, T. H. Vanderford, L. Chennareddi, G. Silvestri, G. J. Freeman, R. Ahmed, and R. R. Amara. 2009. Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature 458:206-210.
-
(2009)
Nature
, vol.458
, pp. 206-210
-
-
Velu, V.1
Titanji, K.2
Zhu, B.3
Husain, S.4
Pladevega, A.5
Lai, L.6
Vanderford, T.H.7
Chennareddi, L.8
Silvestri, G.9
Freeman, G.J.10
Ahmed, R.11
Amara, R.R.12
-
48
-
-
33845954642
-
CD8 T-cell subsets and viral load in the cerebrospinal fluid of therapy-naive HIV-infected individuals
-
von Geldern, G., S. Cepok, T. Nolting, Y. Du, V. Grummel, O. Adams, H. P. Hartung, G. Arendt, and B. Hemmer. 2007. CD8 T-cell subsets and viral load in the cerebrospinal fluid of therapy-naive HIV-infected individuals. AIDS 21:250-253.
-
(2007)
AIDS
, vol.21
, pp. 250-253
-
-
Von Geldern, G.1
Cepok, S.2
Nolting, T.3
Du, Y.4
Grummel, V.5
Adams, O.6
Hartung, H.P.7
Arendt, G.8
Hemmer, B.9
-
49
-
-
24644435009
-
Magnetic resonance spectroscopy reveals that activated monocytes contribute to neuronal injury in SIV neuroAIDS
-
Williams, K., S. Westmoreland, J. Greco, E. Ratai, M. Lentz, W. K. Kim, R. A. Fuller, J. P. Kim, P. Autissier, P. K. Sehgal, R. F. Schinazi, N. Bischofberger, M. Piatak, J. D. Lifson, E. Masliah, and R. G. Gonzalez. 2005. Magnetic resonance spectroscopy reveals that activated monocytes contribute to neuronal injury in SIV neuroAIDS. J. Clin. Investig. 115:2534-2545.
-
(2005)
J. Clin. Investig.
, vol.115
, pp. 2534-2545
-
-
Williams, K.1
Westmoreland, S.2
Greco, J.3
Ratai, E.4
Lentz, M.5
Kim, W.K.6
Fuller, R.A.7
Kim, J.P.8
Autissier, P.9
Sehgal, P.K.10
Schinazi, R.F.11
Bischofberger, N.12
Piatak, M.13
Lifson, J.D.14
Masliah, E.15
Gonzalez, R.G.16
-
50
-
-
0036308234
-
Central nervous system damage, monocytes and macrophages, and neurological disorders in AIDS
-
Williams, K. C., and W. F. Hickey. 2002. Central nervous system damage, monocytes and macrophages, and neurological disorders in AIDS. Annu. Rev. Neurosci. 25:537-562.
-
(2002)
Annu. Rev. Neurosci.
, vol.25
, pp. 537-562
-
-
Williams, K.C.1
Hickey, W.F.2
|