Low and moderate-fat plant sterol fortified soymilk in modulation of plasma lipids and cholesterol kinetics in subjects with normal to high cholesterol concentrations: Report on two randomized crossover studies

Lipids in Health and Disease

Volumn 8, Issue , 2009, Pages

  Rideout, Todd C ^a   Chan, Yen Ming ^a   Harding, Scott V ^a   Jones, Peter J H ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PHYTOSTEROL; TRIACYLGLYCEROL; LIPID;

ANALYSIS OF VARIANCE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL SYNTHESIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET RESTRICTION; DIETARY INTAKE; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; INTESTINE ABSORPTION; LIPID BLOOD LEVEL; LIPID DIET; LOW FAT DIET; MALE; RANDOMIZED CONTROLLED TRIAL; SOYBEAN MILK; TRIACYLGLYCEROL BLOOD LEVEL; BLOOD; CHEMISTRY; DIET THERAPY; FAT INTAKE; KINETICS;

CHOLESTEROL; CHOLESTEROL, LDL; CROSS-OVER STUDIES; DIETARY FATS; HUMANS; HYPERCHOLESTEROLEMIA; KINETICS; LIPIDS; PHYTOSTEROLS; SOY MILK;

EID: 72849122471     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-8-45     Document Type: Article

References (38)

1. A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease. A Mente L de Koning HS Shannon SS Anand, Arch Intern Med 2009 169 7 659 669
2. Fish-oil esters of plant sterols differ from vegetable-oil sterol esters in triglycerides lowering, carotenoid bioavailability and impact on plasminogen activator inhibitor-1 (PAI-1) concentrations in hypercholesterolemic subjects. PJ Jones I Demonty YM Chan Y Herzog D Pelled, Lipids Health Dis 2007 6 28
3. Unesterified plant sterols and stanols lower LDL-cholesterol concentrations equivalently in hypercholesterolemic persons. CA Vanstone M Raeini-Sarjaz WE Parsons PJ Jones, Am J Clin Nutr 2002 76 6 1272 1278
4. Effect of plant sterols in combination with other cholesterol-lowering foods. DJ Jenkins CW Kendall TH Nguyen A Marchie DA Faulkner C Ireland AR Josse E Vidgen EA Trautwein KG Lapsley, et al. Metabolism 2008 57 1 130 139
5. Continuous dose-response relationship of the LDL-cholesterol-lowering effect of phytosterol intake. I Demonty RT Ras HC van der Knaap GS Duchateau L Meijer PL Zock JM Geleijnse EA Trautwein, J Nutr 2009 139 2 271 284
6. Plant sterols: factors affecting their efficacy and safety as functional food ingredients. A Berger PJ Jones SS Abumweis, Lipids Health Dis 2004 3 5
7. Reduced-calorie orange juice beverage with plant sterols lowers C-reactive protein concentrations and improves the lipid profile in human volunteers. S Devaraj BC Autret I Jialal, Am J Clin Nutr 2006 84 4 756 761
8. Effects of long-term plant sterol or stanol ester consumption on lipid and lipoprotein metabolism in subjects on statin treatment. A de Jong J Plat D Lutjohann RP Mensink, Br J Nutr 2008 100 5 937 941
9. Plant sterol esters lower plasma lipids and most carotenoids in mildly hypercholesterolemic adults. JT Judd DJ Baer SC Chen BA Clevidence RA Muesing M Kramer GW Meijer, Lipids 2002 37 1 33 42
10. Phytosterols in low- and nonfat beverages as part of a controlled diet fail to lower plasma lipid levels. PJ Jones CA Vanstone M Raeini-Sarjaz MP St-Onge, J Lipid Res 2003 44 9 1713 1719
11. Effect of low-fat, fermented milk enriched with plant sterols on serum lipid profile and oxidative stress in moderate hypercholesterolemia. B Hansel C Nicolle F Lalanne F Tondu T Lassel Y Donazzolo J Ferrieres M Krempf JL Schlienger B Verges, et al. Am J Clin Nutr 2007 86 3 790 796
12. Comparison between the effects of soymilk and non-fat cow milk on lipid profile and lipid peroxidation in patients with primary hypercholesterolemia. LP Bricarello N Kasinski MC Bertolami A Faludi LA Pinto WG Relvas MC Izar SS Ihara S Tufik FA Fonseca, Nutrition 2004 20 2 200 204
13. Effect of two types of soymilk and dairy milk on plasma lipids in hypercholesterolemic adults: a randomized trial. CD Gardner M Messina A Kiazand JL Morris AA Franke, J Am Coll Nutr 2007 26 6 669 677
14. Double-blind study of the addition of high-protein soya milk v. cows' milk to the diet of patients with severe hypercholesterolaemia and resistance to or intolerance of statins. CR Sirtori F Pazzucconi L Colombo P Battistin A Bondioli K Descheemaeker, Br J Nutr 1999 82 2 91 96
15. Soy protein enhances the cholesterol-lowering effect of plant sterol esters in cholesterol-fed hamsters. Y Lin GW Meijer MA Vermeer EA Trautwein, J Nutr 2004 134 1 143 148
16. Cholesterol lowering effect of a soy drink enriched with plant sterols in a French population with moderate hypercholesterolemia. C Weidner M Krempf JM Bard M Cazaubiel D Bell, Lipids Health Dis 2008 7 35
17. Health effects of soy protein and isoflavones in humans. CW Xiao, J Nutr 2008 138 6 1244S 1249S
18. Effects of phytosterol ester-enriched margarine on plasma lipoproteins in mild to moderate hypercholesterolemia are related to basal cholesterol and fat intake. MJ Mussner KG Parhofer K Von Bergmann P Schwandt U Broedl C Otto, Metabolism 2002 51 2 189 194
19. Plant sterols/stanols as cholesterol lowering agents: A meta-analysis of randomized controlled trials. SS Abumweis R Barake PJ Jones, Food Nutr Res 2008
20. Sitostanol administered in lecithin micelles potently reduces cholesterol absorption in humans. RE Ostlund Jr CA Spilburg WF Stenson, Am J Clin Nutr 1999 70 5 826 831 10539742
21. Effects on serum lipids, lipoproteins and fat soluble antioxidant concentrations of consumption frequency of margarines and shortenings enriched with plant stanol esters. J Plat EN van Onselen MM van Heugten RP Mensink, Eur J Clin Nutr 2000 54 9 671 677
22. A plant stanol yogurt drink alone or combined with a low-dose statin lowers serum triacylglycerol and non-HDL cholesterol in metabolic syndrome patients. J Plat G Brufau GM Dallinga-Thie M Dasselaar RP Mensink, J Nutr 2009 139 6 1143 1149
23. The baseline serum lipoprotein profile is related to plant stanol induced changes in serum lipoprotein cholesterol and triacylglycerol concentrations. E Naumann J Plat AD Kester RP Mensink, J Am Coll Nutr 2008 27 1 117 126
24. Association between non-responsiveness to plant sterol intervention and polymorphisms in cholesterol metabolism genes: a case-control study. I Rudkowska SS Abumweis C Nicolle PJ Jones, Appl Physiol Nutr Metab 2008 33 4 728 734
25. Genetic Variation in ABC G5/G8 and NPC1L1 Impact Cholesterol Response to Plant Sterols in Hypercholesterolemic Men. HL Zhao AH Houweling CA Vanstone S Jew EA Trautwein GS Duchateau PJ Jones, Lipids 2008 43 12 1155 1164
26. Inhibition of cholesterol absorption in rats by plant sterols. I Ikeda K Tanaka M Sugano GV Vahouny LL Gallo, J Lipid Res 1988 29 12 1573 1582 (Pubitemid 19030525)
27. Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis. HR Davis Jr LJ Zhu LM Hoos G Tetzloff M Maguire J Liu X Yao SP Iyer MH Lam EG Lund, et al. J Biol Chem 2004 279 32 33586 33592
28. Compared with Acyl-CoA:cholesterol O-acyltransferase (ACAT) 1 and lecithin:cholesterol acyltransferase, ACAT2 displays the greatest capacity to differentiate cholesterol from sitosterol. RE Temel AK Gebre JS Parks LL Rudel, J Biol Chem 2003 278 48 47594 47601
29. Plant sterol consumption frequency affects plasma lipid levels and cholesterol kinetics in humans. SS AbuMweis CA Vanstone AH Lichtenstein PJ Jones, Eur J Clin Nutr 2009 63 6 747 755
30. Modulation of plasma lipid levels and cholesterol kinetics by phytosterol versus phytostanol esters. PJ Jones M Raeini-Sarjaz FY Ntanios CA Vanstone JY Feng WE Parsons, J Lipid Res 2000 41 5 697 705
31. Isoflavone-poor soy protein alters the lipid metabolism of rats by SREBP-mediated down-regulation of hepatic genes. A Shukla C Brandsch A Bettzieche F Hirche GI Stangl K Eder, J Nutr Biochem 2007 18 5 313 321
32. A soy protein diet alters hepatic lipid metabolism gene expression and reduces serum lipids and renal fibrogenic cytokines in rats with chronic nephrotic syndrome. AR Tovar F Murguia C Cruz R Hernandez-Pando CA Aguilar-Salinas J Pedraza-Chaverri R Correa-Rotter N Torres, J Nutr 2002 132 9 2562 2569
33. Soy protein reduces triglyceride levels and triglyceride fatty acid fractional synthesis rate in hypercholesterolemic subjects. Y Wang PJ Jones LM Ausman AH Lichtenstein, Atherosclerosis 2004 173 2 269 275
34. A new predictive equation for resting energy expenditure in healthy individuals. MD Mifflin ST St Jeor LA Hill BJ Scott SA Daugherty YO Koh, Am J Clin Nutr 1990 51 2 241 247
35. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. WT Friedewald RI Levy DS Fredrickson, Clin Chem 1972 18 6 499 502
36. A simple method for the isolation and purification of total lipides from animal tissues. J Folch M Lees GH Sloane Stanley, J Biol Chem 1957 226 1 497 509
37. Human cholesterol synthesis measurement using deuterated water. Theoretical and procedural considerations. PJ Jones CA Leitch ZC Li WE Connor, Arterioscler Thromb 1993 13 2 247 253
38. Use of deuterated water for measurement of short-term cholesterol synthesis in humans. PJ Jones, Can J Physiol Pharmacol 1990 68 7 955 959