Fluorescence and UV resonance Raman study of peptide-vesicle interactions of human cathelicidin LL-37 and its F6W and F17W mutants

Biochemistry

Volumn 48, Issue 47, 2009, Pages 11264-11272

  Gable, Jonathan E ^a   Schlamadinger, Diana E ^a   Cogen, Anna L ^a,b   Gallo, Richard L ^a,c   Kim, Judy E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMICROBIAL ACTION; ANTIMICROBIAL PEPTIDE; BI-LAYER; CARBONATE IONS; CATHELICIDIN; DISTILLED WATER; ENVIRONMENT POLARITY; HEAD GROUPS; HYDROGEN BOND STRENGTH; HYDROPHOBIC REGIONS; LIPID VESICLES; LOCAL ENVIRONMENTS; LYSINE RESIDUES; MEMBRANE DISRUPTION; MICROENVIRONMENTS; MINIMAL INHIBITORY CONCENTRATION; POTENCY ASSAY; ROTATIONAL FREEDOM; SPECTROSCOPIC PROPERTY; SPECTROSCOPIC TOOL; STEADY-STATE FLUORESCENCE; TRYPTOPHAN MUTANT; TRYPTOPHAN RESIDUES; UV RESONANCE RAMAN; UV-RESONANCE RAMAN SPECTROSCOPY; VESICLE LEAKAGE;

AMINES; BINDING SITES; BOND STRENGTH (MATERIALS); BROMINE; CARBONATION; FLUORESCENCE; HYDROGEN; HYDROGEN BONDS; PEPTIDES; POLYPEPTIDES; QUENCHING; RAMAN SPECTROSCOPY; RESONANCE;

AMINO ACIDS;

CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; MUTANT PROTEIN;

ALPHA HELIX; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; FLUORESCENCE SPECTROSCOPY; HUMAN; HYDROGEN BOND; MEMBRANE DAMAGE; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; RAMAN SPECTROMETRY; STEADY STATE; ULTRAVIOLET SPECTROSCOPY;

ANTIMICROBIAL CATIONIC PEPTIDES; BROMINE; HUMANS; HYDROGEN BONDING; LYSINE; MEMBRANE LIPIDS; MODELS, MOLECULAR; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTRUM ANALYSIS, RAMAN; TRYPTOPHAN;

EID: 72749098602     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900996q     Document Type: Article

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