Structure-function studies on inhibitory activity of Bungarus multicinctus protease inhibitor-like protein on matrix metalloprotease-2, and invasion and migration of human neuroblastoma SK-N-SH cells

Toxicon

Volumn 55, Issue 2-3, 2010, Pages 353-360

  Chou, Wen Min ^a   Liu, Wen Hsin ^a   Chen, Ku Chung ^a   Chang, Long Sen ^a  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Cell invasion; Cell migration; Metalloproteinase inhibitor; Molecular model; Protease inhibitor

Indexed keywords

AMINO ACID; GELATINASE A; PROTEASE INHIBITOR LIKE PROTEIN 2; PROTEASE INHIBITOR LIKE PROTEIN 3; RECOMBINANT PROTEIN; SERINE PROTEINASE INHIBITOR; SNAKE VENOM; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BULGARUS MULTICINCTUS; CANCER CELL CULTURE; CARBOXY TERMINAL SEQUENCE; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR DOCKING; MOLECULAR MODEL; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SNAKE; STRUCTURE ACTIVITY RELATION; ZYMOGRAPHY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BRAIN NEOPLASMS; BUNGARUS; CELL LINE, TUMOR; CELL MOVEMENT; ELAPID VENOMS; HUMANS; MATRIX METALLOPROTEINASE 2; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASM INVASIVENESS; NEUROBLASTOMA; PROTEASE INHIBITORS; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; WOUND HEALING;

BUNGARUS MULTICINCTUS;

EID: 72749097878     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2009.08.012     Document Type: Article

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