ROS-mediated p38α MAPK activation and ERK inactivation responsible for upregulation of Fas and FasL and autocrine Fas-mediated cell death in Taiwan cobra phospholipase A2-treated U937 cells

Journal of Cellular Physiology

Volumn 219, Issue 3, 2009, Pages 642-651

  Liu, Wen Hsin ^a   Cheng, Yun Ching ^a   Chang, Long Sen ^a  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CASPASE 3; CASPASE 9; CYTOCHROME C; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 14; PHOSPHOLIPASE A2; PROCASPASE 8; REACTIVE OXYGEN METABOLITE; MITOGEN ACTIVATED PROTEIN KINASE P38; PRIMER DNA; SNAKE VENOM;

APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CATALYSIS; CELL DEATH; CELL STRAIN U937; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INACTIVATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SNAKE; UPREGULATION; ANIMAL; BIOLOGICAL MODEL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; IN VITRO STUDY; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MONONUCLEAR CELL; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; TAIWAN;

NAJA ATRA;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; BASE SEQUENCE; COBRA; COBRA VENOMS; CYTOCHROMES C; DNA PRIMERS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FAS LIGAND PROTEIN; HUMANS; LEUKOCYTES, MONONUCLEAR; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIAL, MITOCHONDRIAL; MODELS, BIOLOGICAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOLIPASES A2; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TAIWAN; U937 CELLS; UP-REGULATION;

EID: 64549083329     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21713     Document Type: Article

References (43)

1. Abramson N, Melton B. 2000. Leukocytosis: Basics of clinical assessment. Am Fam Physician 62:2053-2060.
2. Annunziato L, Amoroso S, Pannaccione A, Cataldi M, Pignataro G, D'Alessio A, Sirabella R, Secondo A, Sibaud L, Di Renzo GF. 2003. Apoptosis induced in neuronal cells by oxidative stress: Role played by caspases and intracellular calcium ions. Toxicol Lett 139:125-133. (Pubitemid 36298971)
3. 2 modulates respiratory burst developed by neutrophils in patients with rheumatoid arthritis. J Cell Mol Med 7:57-66.
4. Bragado P, Armesilla A, Silva A, Porras A. 2007. Apoptosis by cisplatin requires p53 mediated p38α MAPK activation through ROS generation. Apoptosis 12:1733-1742.
5. Brookes PS, Yoon Y, Robotham JL, Anders MW, Sheu SS. 2004. Calcium, ATP, and ROS: A mitochondrial love-hate triangle. Am J Physiol Cell Physiol 287:C817-C833. (Pubitemid 39238305)
6. 2: Mediators of inflammation, proliferation and apoptosis. Prog Lipid Res 40:167-197.
7. Chang LS, Lin SR, Chang CC. 1998. Identification of Arg-30 as the essential residue for the enzymatic activity of Taiwan cobra phospholipase A2. J Biochem (Tokyo) 124:764-768. (Pubitemid 28488155)
8. Cheng B, Song J, Zou Y, Wang Q, Lei Y, Zhu C, Hu C. 2008. Responses of vascular smooth muscle cells to estrogen are dependent on balance between ERK and p38 MAPK pathway activities. Int J Cardiol 10.1016/j.ijcard.2008.02.017.
9. Cherny VV, Henderson LM, Xu W, Thomas LL, DeCoursey TE. 2001. Activation of NADPH oxidase-related proton and electron currents in human eosinophils by arachidonic acid. J Physiol 535:783-794. (Pubitemid 32894489)
10. 2. Toxicon 51:270-279.
11. Del Poeta G, Venditti A, Del Principe MI, Maurillo L, Buccisano F, Tamburini A, Cox MC, Franchi A, Bruno A, Mazzone C, Panetta P, Suppo G, Masi M, Amadori S. 2003. Amount of spontaneous apoptosis detected by Bax/Bcl-2 ratio predicts outcome in acute myeloid leukemia (AML). Blood 101:2125-2131. (Pubitemid 36302046)
12. Dolado I, Swat A, Ajenjo N, De Vita G, Cuadrado A, Nebreda AR. 2007. p38α MAP kinase as a sensor of reactive oxygen species in tumorigenesis. Cancer Cell 11:191-205.
13. Enslen H, Raingeaud J, Davis RJ. 2000a. Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6. J Biol Chem 273:1741-1748.
14. Enslen H, Brancho DM, Davis RJ. 2000b. Molecular determinants that mediate selective activation of p38 MAP kinase isoforms. EMBO J 19:1301-1311. (Pubitemid 30151026)
15. 2: A perspective on the history. Prostaglandins Leukot Essent Fatty Acids 71:161-169.
16. 2. FEBS Lett 531:7-11.
17. Green DR, Reed JC. 1998. Mitochondria and apoptosis. Science 281:1309-1312. (Pubitemid 28406816)
18. Hengartner MO. 2000. The biochemistry of apoptosis. Nature 407:700-706.
19. Hsu SC, Gavrilin MA, Tsai MH, Han J, Lai MZ. 1999. p38 mitogen-activated protein kinase is involved in Fas ligand expression. J Biol Chem 274:25769-25776. (Pubitemid 129530753)
20. Junttila MR, Li SP, Westermarck J. 2008. Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J 22:954-965.
21. 2. J Peptide Sci 14:342-348.
22. Kim JK, Pedram A, Razandi M, Levin ER. 2006. Estrogen prevents cardiomyocyte apoptosis through inhibition of reactive oxygen species and differential regulation of p38 kinase isoforms. J Biol Chem 281:6760-6767. (Pubitemid 43847612)
23. Krishna M, Narang H. 2008. The complexity of mitogen-activated protein kinases (MAPKs) made simple. Cell Mol Life Sci 65:3525-3544.
24. Kroemer G, Dallaporta B, Resche-Rigon M. 1998. The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol 60:619-642. (Pubitemid 28157889)
25. Kumar S, McDonnell PC, Gum RJ, Hand AT, Lee JC, Young PR. 1997. Novel homologues of CSBP/p38 MAP kinase activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles. Biochem Biophys Res Commun 235:533-538. (Pubitemid 27326515)
26. 2 induces apoptosis through TNF-α and cytochrome c-mediated caspase cascade in murine macrophage RAW 264.7 cells. Eur J Pharmacol 536:47-53.
27. Narita M, Shimizu S, Ito T, Chittenden T, Lutz RJ, Matsuda H, Tsujimoto Y. 1998. Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc Natl Acad Sci USA 95:14681-14686. (Pubitemid 29003690)
28. Ott M, Gogvadze V, Orrenius S. 2007. Mitochondria, oxidative stress and cell death. Apoptosis 12:913-922. (Pubitemid 46653300)
29. Pompeia C, Cury-Boaventura MF, Curi R. 2003. Arachidonic acid triggers an oxidative burst in leukocytes. Braz J Med Biol Res 36:1549-1560. (Pubitemid 37408044)
30. Porras A, Zuluaga S, Black E, ValladaresA, Alvarez AM, Amnrosino C, Benito M, Nebreda AR. 2004. p38α mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. Mol Biol Cell 15:922-933. (Pubitemid 38146504)
31. Proskuryakov SY, Konoplyannikov AG, Gabai VL. 2003. Necrosis: A specific form of programmed cell death? Exp Cell Res 283:1-16.
32. Schneider E, Cowan KH, Bader H, Toomey S, Schwartz GN, Karp JE, Burke PJ, Kaufmann SH. 1995. Increased expression of the multidrug resistance-associated protein gene in relapsed acute leukemia. Blood 85:186-193.
33. Simon HU, Haj-Yehia A, Levi-Schaffer F. 2000. Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis 5:415-418. (Pubitemid 32162623)
34. 2 in central nervous system: Implications for neurodegenerative diseases. J Lipid Res 45:205-213.
35. 2 in oxidative and inflammatory responses in neurodegenerative diseases. J Neurochem 103:1-16.
36. 2 and apoptosis. Biochim Biophys Acta 1585:72-76.
37. Testa U, Riccioni R. 2007. Deregulation of apoptosis in acute myeloid leukemia. Haematologica 92:81-94. (Pubitemid 46237556)
38. Thorburn A. 2004. Death receptor-induced cell killing. Cell Signal 16:139-144. (Pubitemid 37431163)
39. 2 induce β-glucuronidase release and IL-6 production from human lung macrophages. J Immunol 164:4908-4915.
40. Wang X. 2001. The expanding role of mitochondria in apoptosis. Genes Dev 15:2922-2933. (Pubitemid 33078942)
41. Wang ZY. 2003. Ham-Wasserman lecture: Treatment of acute leukemia by inducing differentiation and apoptosis. Hematology 1:1-13.
42. Yu C, Rahmani M, Dent P, Grant S. 2004. The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib. Exp Cell Res 295:555-566. (Pubitemid 38490507)
43. Zhang X, Shan P, Alam J, Davis RJ, Flavell RA, Lee PJ. 2003. Carbon monoxide modulates Fas/ Fas ligand, caspases, and Bcl-2 family proteins via the p38α mitogen-activated protein kinase pathway during ischemia-reperfusion lung injury. J Biol Chem 278:22061-22070. (Pubitemid 36792616)