LPS-induced indoleamine 2,3-dioxygenase is regulated in an interferon-γ-independent manner by a JNK signaling pathway in primary murine microglia

Brain, Behavior, and Immunity

Volumn 24, Issue 2, 2010, Pages 201-209

  Wang, Yunxia ^a,b   Lawson, Marcus A ^a   Dantzer, Robert ^a   Kelley, Keith W ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

c Jun N terminal kinase; Indoleamine 2,3 dioxygenase; Lipopolysaccharide; Neuroinflammation; Primary microglia

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 6; KYNURENINE; LIPOPOLYSACCHARIDE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DEPRESSION; ENZYME ACTIVITY; GENE EXPRESSION; INFLAMMATION; MICROGLIA; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRYPTOPHAN METABOLISM;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; INDICATORS AND REAGENTS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INTERFERON-GAMMA; KYNURENINE; LIPOPOLYSACCHARIDES; MAP KINASE KINASE 4; MICE; MICE, INBRED C57BL; MICROGLIA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SIGNAL TRANSDUCTION;

EID: 72649104599     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2009.06.152     Document Type: Article

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