-
1
-
-
0022640843
-
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
-
1:CAS:528:DyaL28XhvVClsbk%3D 2419430
-
TR Mosmann H Cherwinski MW Bond MA Giedlin RL Coffman 1986 Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins J Immunol 136 2348 57 1:CAS:528: DyaL28XhvVClsbk%3D 2419430
-
(1986)
J Immunol
, vol.136
, pp. 2348-57
-
-
Mosmann, T.R.1
Cherwinski, H.2
Bond, M.W.3
Giedlin, M.A.4
Coffman, R.L.5
-
2
-
-
0023622458
-
Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies
-
10.1084/jem.166.5.1229 1:CAS:528:DyaL1cXitVaqtbk%3D 2960769
-
HM Cherwinski JH Schumacher KD Brown TR Mosmann 1987 Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies J Exp Med 166 1229 44 10.1084/jem.166.5. 1229 1:CAS:528:DyaL1cXitVaqtbk%3D 2960769
-
(1987)
J Exp Med
, vol.166
, pp. 1229-44
-
-
Cherwinski, H.M.1
Schumacher, J.H.2
Brown, K.D.3
Mosmann, T.R.4
-
4
-
-
0025807152
-
Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production
-
10.1172/JCI115300 1:CAS:528:DyaK3MXkvFSntLs%3D 1829097
-
GF Del Prete M De Carli C Mastromauro R Biagiotti D Macchia P Falagiani M Ricci S Romagnani 1991 Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production J Clin Invest 88 346 50 10.1172/JCI115300 1:CAS:528:DyaK3MXkvFSntLs%3D 1829097
-
(1991)
J Clin Invest
, vol.88
, pp. 346-50
-
-
Del Prete, G.F.1
De Carli, M.2
Mastromauro, C.3
Biagiotti, R.4
MacChia, D.5
Falagiani, P.6
Ricci, M.7
Romagnani, S.8
-
5
-
-
0029847368
-
Functional diversity of helper T lymphocytes
-
DOI 10.1038/383787a0
-
AK Abbas KM Murphy A Sher 1996 Functional diversity of helper T lymphocytes Nature 383 787 93 10.1038/383787a0 1:CAS:528:DyaK28XmsF2qsLY%3D 8893001 (Pubitemid 26372655)
-
(1996)
Nature
, vol.383
, Issue.6603
, pp. 787-793
-
-
Abbas, A.K.1
Murphy, K.M.2
Sher, A.3
-
6
-
-
0036885067
-
The lineage decisions of helper T cells
-
DOI 10.1038/nri954
-
KM Murphy SL Reiner 2002 The lineage decisions of helper T cells Nat Rev Immunol 2 933 44 10.1038/nri954 1:CAS:528:DC%2BD38XptFKnu7g%3D 12461566 (Pubitemid 37323214)
-
(2002)
Nature Reviews Immunology
, vol.2
, Issue.12
, pp. 933-944
-
-
Murphy, K.M.1
Reiner, S.L.2
-
7
-
-
0038195719
-
Molecular mechanisms regulating Th1 immune responses
-
DOI 10.1146/annurev.immunol.21.120601.140942
-
SJ Szabo BM Sullivan SL Peng LH Glimcher 2003 Molecular mechanisms regulating Th1 immune responses Annu Rev Immunol 21 713 58 10.1146/annurev. immunol.21.120601.140942 1:CAS:528:DC%2BD3sXjtF2is7k%3D 12500979 (Pubitemid 37174546)
-
(2003)
Annual Review of Immunology
, vol.21
, pp. 713-758
-
-
Szabo, S.J.1
Sullivan, B.M.2
Peng, S.L.3
Glimcher, L.H.4
-
8
-
-
9644262463
-
Signaling pathways in Th2 development
-
DOI 10.1111/j.0105-2896.2004.00209.x
-
KA Mowen LH Glimcher 2004 Signaling pathways in Th2 development Immunol Rev 202 203 22 10.1111/j.0105-2896.2004.00209.x 1:CAS:528:DC%2BD2MXhs1Ohtw%3D%3D 15546395 (Pubitemid 39576914)
-
(2004)
Immunological Reviews
, vol.202
, pp. 203-222
-
-
Mowen, K.A.1
Glimcher, L.H.2
-
9
-
-
0035062386
-
IL-12-induced reversal of human Th2 cells is accompanied by full restoration of IL-12 responsiveness and loss of GATA-3 expression
-
DOI 10.1002/1521-4141(200104)31:4<1055::AID-IMMU1055>3.0.CO;2-7
-
HH Smits JG van Rietschoten CM Hilkens R Sayilir F Stiekema ML Kapsenberg EA Wierenga 2001 IL-12-induced reversal of human Th2 cells is accompanied by full restoration of IL-12 responsiveness and loss of GATA-3 expression Eur J Immunol 31 1055 65 10.1002/1521-4141(200104)31:4<1055::AID-IMMU1055>3.0. CO;2-7 1:CAS:528:DC%2BD3MXivFyjsr4%3D 11298330 (Pubitemid 32331610)
-
(2001)
European Journal of Immunology
, vol.31
, Issue.4
, pp. 1055-1065
-
-
Harris, S.G.1
Phipps, R.P.2
-
10
-
-
47549112840
-
IL-21 and TGF-beta are required for differentiation of human T(H)17 cells
-
10.1038/nature07021 1:CAS:528:DC%2BD1cXosFCqs7o%3D 18469800
-
L Yang DE Anderson C Baecher-Allan WD Hastings E Bettelli M Oukka VK Kuchroo DA Hafler 2008 IL-21 and TGF-beta are required for differentiation of human T(H)17 cells Nature 454 350 2 10.1038/nature07021 1:CAS:528: DC%2BD1cXosFCqs7o%3D 18469800
-
(2008)
Nature
, vol.454
, pp. 350-2
-
-
Yang, L.1
Anderson, D.E.2
Baecher-Allan, C.3
Hastings, W.D.4
Bettelli, E.5
Oukka, M.6
Kuchroo, V.K.7
Hafler, D.A.8
-
11
-
-
44049104564
-
H-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
-
DOI 10.1038/ni.1610, PII NI.1610
-
N Manel D Unutmaz DR Littman 2008 The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat Nat Immunol 9 641 9 10.1038/ni.1610 1:CAS:528: DC%2BD1cXmtVWqurg%3D 18454151 (Pubitemid 351714729)
-
(2008)
Nature Immunology
, vol.9
, Issue.6
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
12
-
-
34548125305
-
Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells
-
DOI 10.1038/ni1496, PII NI1496
-
EV Acosta-Rodriguez G Napolitani A Lanzavecchia F Sallusto 2007 Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells Nat Immunol 8 942 9 10.1038/ni1496 1:CAS:528:DC%2BD2sXptlSku7w%3D 17676045 (Pubitemid 47300008)
-
(2007)
Nature Immunology
, vol.8
, Issue.9
, pp. 942-949
-
-
Acosta-Rodriguez, E.V.1
Napolitani, G.2
Lanzavecchia, A.3
Sallusto, F.4
-
13
-
-
32244442562
-
TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
DOI 10.1016/j.immuni.2006.01.001, PII S1074761306000045
-
M Veldhoen RJ Hocking CJ Atkins RM Locksley B Stockinger 2006 TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells Immunity 24 179 89 10.1016/j.immuni.2006.01.001 1:CAS:528:DC%2BD28XitVOks7s%3D 16473830 (Pubitemid 43214587)
-
(2006)
Immunity
, vol.24
, Issue.2
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
14
-
-
0027959893
-
Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype
-
1:CAS:528:DyaK2cXmsFensbY%3D 7930573
-
S Sad TR Mosmann 1994 Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype J Immunol 153 3514 22 1:CAS:528:DyaK2cXmsFensbY%3D 7930573
-
(1994)
J Immunol
, vol.153
, pp. 3514-22
-
-
Sad, S.1
Mosmann, T.R.2
-
15
-
-
0032856952
-
Primed and replicating but uncommitted T helper precursor cells show kinetics of differentiation and commitment similar to those of naive T helper cells
-
DOI 10.1016/S1286-4579(99)80014-8
-
PS Akai TR Mosmann 1999 Primed and replicating but uncommitted T helper precursor cells show kinetics of differentiation and commitment similar to those of naive T helper cells Microbes Infect 1 51 8 10.1016/S1286-4579(99)80014-8 1:STN:280:DC%2BD3czgtlKktA%3D%3D 10847766 (Pubitemid 29364912)
-
(1999)
Microbes and Infection
, vol.1
, Issue.1
, pp. 51-58
-
-
Akai, P.S.1
Mosmann, T.R.2
-
16
-
-
0035886928
-
In vivo priming of CD4 T cells that produce interleukin (IL)-2 but not IL-4 or interferon (IFN)-γ, and can subsequently differentiate into IL-4- or IFN-γ-secreting cells
-
DOI 10.1084/jem.194.8.1069
-
X Wang T Mosmann 2001 In vivo priming of CD4 T cells that produce interleukin (IL)-2 but not IL-4 or interferon (IFN)-gamma, and can subsequently differentiate into IL-4- or IFN-gamma-secreting cells J Exp Med 194 1069 80 10.1084/jem.194.8.1069 1:CAS:528:DC%2BD3MXnslGju7c%3D 11602637 (Pubitemid 32995778)
-
(2001)
Journal of Experimental Medicine
, vol.194
, Issue.8
, pp. 1069-1080
-
-
Wang, X.1
Mosmann, T.2
-
17
-
-
0033554726
-
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
-
DOI 10.1038/44385
-
F Sallusto D Lenig R Forster M Lipp A Lanzavecchia 1999 Two subsets of memory T lymphocytes with distinct homing potentials and effector functions Nature 401 708 12 10.1038/44385 1:CAS:528:DyaK1MXntVWntrw%3D 10537110 (Pubitemid 29485217)
-
(1999)
Nature
, vol.401
, Issue.6754
, pp. 708-712
-
-
Sallusto, F.1
Lenig, D.2
Forster, R.3
Lipp, M.4
Lanzavecchia, A.5
-
18
-
-
0037340417
-
Lineage relationship and protective immunity of memory CD8T cell subsets
-
DOI 10.1038/ni889
-
EJ Wherry V Teichgraber TC Becker D Masopust SM Kaech R Antia UH von Andrian R Ahmed 2003 Lineage relationship and protective immunity of memory CD8 T cell subsets Nat Immunol 4 225 34 10.1038/ni889 1:CAS:528:DC%2BD3sXhsVGisLY%3D 12563257 (Pubitemid 36322131)
-
(2003)
Nature Immunology
, vol.4
, Issue.3
, pp. 225-234
-
-
Wherry, E.J.1
Teichgraber, V.2
Becker, T.C.3
Masopust, D.4
Kaech, S.M.5
Antia, R.6
Von Andrian, U.H.7
Ahmed, R.8
-
19
-
-
23944461953
-
+ T cell lineage commitment
-
DOI 10.1038/ni1227, PII N1227
-
AL Marzo KD Klonowski A Le Bon P Borrow DF Tough L Lefrancois 2005 Initial T cell frequency dictates memory CD8+ T cell lineage commitment Nat Immunol 6 793 9 10.1038/ni1227 1:CAS:528:DC%2BD2MXmtlSisLc%3D 16025119 (Pubitemid 43090465)
-
(2005)
Nature Immunology
, vol.6
, Issue.8
, pp. 793-799
-
-
Marzo, A.L.1
Klonowski, K.D.2
Le Bon, A.3
Borrow, P.4
Tough, D.F.5
Lefrancois, L.6
-
20
-
-
7044254507
-
Central memory T cells mediate long-term immunity to Leishmania major in the absence of persistent parasites
-
DOI 10.1038/nm1108
-
C Zaph J Uzonna SM Beverley P Scott 2004 Central memory T cells mediate long-term immunity to Leishmania major in the absence of persistent parasites Nat Med 10 1104 10 10.1038/nm1108 1:CAS:528:DC%2BD2cXnvFyntb0%3D 15448686 (Pubitemid 39424872)
-
(2004)
Nature Medicine
, vol.10
, Issue.10
, pp. 1104-1110
-
-
Zaph, C.1
Uzonna, J.2
Beverley, S.M.3
Scott, P.4
-
21
-
-
0035905477
-
+ T cells
-
DOI 10.1084/jem.194.12.1711
-
J Geginat F Sallusto A Lanzavecchia 2001 Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells J Exp Med 194 1711 9 10.1084/jem.194.12.1711 1:CAS:528:DC%2BD38Xpt1Wm 11748273 (Pubitemid 34028651)
-
(2001)
Journal of Experimental Medicine
, vol.194
, Issue.12
, pp. 1711-1719
-
-
Geginat, J.1
Sallusto, F.2
Lanzavecchia, A.3
-
22
-
-
0035854521
-
Arrested differentiation, the self-renewing memory lymphocyte, vaccination
-
DOI 10.1126/science.1062589
-
DT Fearon P Manders SD Wagner 2001 Arrested differentiation, the self-renewing memory lymphocyte, and vaccination Science 293 248 50 10.1126/science.1062589 1:CAS:528:DC%2BD3MXlt1yisL8%3D 11452114 (Pubitemid 32694731)
-
(2001)
Science
, vol.293
, Issue.5528
, pp. 248-250
-
-
Fearon, D.T.1
Manders, P.2
Wagner, S.D.3
-
23
-
-
31144457737
-
Protein vaccines induce uncommitted IL-2-secreting human and mouse CD4 T cells, whereas infections induce more IFN-gamma-secreting cells
-
1:CAS:528:DC%2BD28XlsFyhug%3D%3D 16424174
-
AA Divekar DM Zaiss FE Lee D Liu DJ Topham AJ Sijts TR Mosmann 2006 Protein vaccines induce uncommitted IL-2-secreting human and mouse CD4 T cells, whereas infections induce more IFN-gamma-secreting cells J Immunol 176 1465 73 1:CAS:528:DC%2BD28XlsFyhug%3D%3D 16424174
-
(2006)
J Immunol
, vol.176
, pp. 1465-73
-
-
Divekar, A.A.1
Zaiss, D.M.2
Lee, F.E.3
Liu, D.4
Topham, D.J.5
Sijts, A.J.6
Mosmann, T.R.7
-
24
-
-
3242733265
-
Synthesis of several chemokines but few cytokines by primed uncommitted precursor CD4 T cells suggests that these cells recruit other immune cells without exerting direct effector functions
-
DOI 10.1002/eji.200424939
-
L Yang T Mosmann 2004 Synthesis of several chemokines but few cytokines by primed uncommitted precursor CD4 T cells suggests that these cells recruit other immune cells without exerting direct effector functions Eur J Immunol 34 1617 26 10.1002/eji.200424939 1:CAS:528:DC%2BD2cXltFKru78%3D 15162431 (Pubitemid 39256043)
-
(2004)
European Journal of Immunology
, vol.34
, Issue.6
, pp. 1617-1626
-
-
Yang, L.1
Mosmann, T.2
-
25
-
-
27744484754
-
CD73 and Ly-6A/E distinguish in vivo primed but uncommitted mouse CD4 T cells from type 1 or type 2 effector cells
-
1:CAS:528:DC%2BD2MXhtF2jurvM 16272299
-
L Yang JJ Kobie TR Mosmann 2005 CD73 and Ly-6A/E distinguish in vivo primed but uncommitted mouse CD4 T cells from type 1 or type 2 effector cells J Immunol 175 6458 64 1:CAS:528:DC%2BD2MXhtF2jurvM 16272299
-
(2005)
J Immunol
, vol.175
, pp. 6458-64
-
-
Yang, L.1
Kobie, J.J.2
Mosmann, T.R.3
-
26
-
-
33750832563
-
T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′-adenosine monophosphate to adenosine
-
1:CAS:528:DC%2BD28XhtFGrtrzO 17082591
-
JJ Kobie PR Shah L Yang JA Rebhahn DJ Fowell TR Mosmann 2006 T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′-adenosine monophosphate to adenosine J Immunol 177 6780 6 1:CAS:528:DC%2BD28XhtFGrtrzO 17082591
-
(2006)
J Immunol
, vol.177
, pp. 6780-6
-
-
Kobie, J.J.1
Shah, P.R.2
Yang, L.3
Rebhahn, J.A.4
Fowell, D.J.5
Mosmann, T.R.6
-
27
-
-
0027937374
-
Heterogeneity of single cell cytokine gene expression in clonal T cell populations
-
10.1084/jem.180.4.1251 1:CAS:528:DyaK2cXlslOnsLc%3D 7523568
-
RP Bucy A Panoskaltsis-Mortari GQ Huang J Li L Karr M Ross JH Russell KM Murphy CT Weaver 1994 Heterogeneity of single cell cytokine gene expression in clonal T cell populations J Exp Med 180 1251 62 10.1084/jem.180.4.1251 1:CAS:528:DyaK2cXlslOnsLc%3D 7523568
-
(1994)
J Exp Med
, vol.180
, pp. 1251-62
-
-
Bucy, R.P.1
Panoskaltsis-Mortari, A.2
Huang, G.Q.3
Li, J.4
Karr, L.5
Ross, M.6
Russell, J.H.7
Murphy, K.M.8
Weaver, C.T.9
-
28
-
-
0029160098
-
Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development
-
10.1073/pnas.92.16.7565 1:CAS:528:DyaK2MXntlKlsrc%3D 7638231
-
RP Bucy L Karr GQ Huang J Li D Carter K Honjo JA Lemons KM Murphy CT Weaver 1995 Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development Proc Natl Acad Sci USA 92 7565 9 10.1073/pnas.92.16.7565 1:CAS:528:DyaK2MXntlKlsrc%3D 7638231
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7565-9
-
-
Bucy, R.P.1
Karr, L.2
Huang, G.Q.3
Li, J.4
Carter, D.5
Honjo, K.6
Lemons, J.A.7
Murphy, K.M.8
Weaver, C.T.9
-
29
-
-
0032900121
-
Single-cell analysis by RT-PCR reveals differential expression of multiple type 1 and 2 cytokine genes among cells within polarized CD4+ T cell populations
-
10.1093/intimm/11.4.617 1:CAS:528:DyaK1MXivVeksbk%3D 10323215
-
A Kelso P Groves L Ramm AG Doyle 1999 Single-cell analysis by RT-PCR reveals differential expression of multiple type 1 and 2 cytokine genes among cells within polarized CD4+ T cell populations Int Immunol 11 617 21 10.1093/intimm/11.4.617 1:CAS:528:DyaK1MXivVeksbk%3D 10323215
-
(1999)
Int Immunol
, vol.11
, pp. 617-21
-
-
Kelso, A.1
Groves, P.2
Ramm, L.3
Doyle, A.G.4
-
30
-
-
0028267766
-
Flow cytometric determination of cytokines in activated murine T helper lymphocytes: Expression of interleukin-10 in interferon-gamma and in interleukin-4-expressing cells
-
10.1002/eji.1830240513 1:CAS:528:DyaK2cXktVKqtb4%3D 7910138
-
M Assenmacher J Schmitz A Radbruch 1994 Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of interleukin-10 in interferon-gamma and in interleukin-4-expressing cells Eur J Immunol 24 1097 101 10.1002/eji.1830240513 1:CAS:528:DyaK2cXktVKqtb4%3D 7910138
-
(1994)
Eur J Immunol
, vol.24
, pp. 1097-101
-
-
Assenmacher, M.1
Schmitz, J.2
Radbruch, A.3
-
31
-
-
0034651907
-
Single-cytokine-producing CD4 memory cells predominate in type 1 and type 2 immunity
-
1:CAS:528:DC%2BD3cXhtlymtL8%3D 10657635
-
AY Karulin MD Hesse M Tary-Lehmann PV Lehmann 2000 Single-cytokine- producing CD4 memory cells predominate in type 1 and type 2 immunity J Immunol 164 1862 72 1:CAS:528:DC%2BD3cXhtlymtL8%3D 10657635
-
(2000)
J Immunol
, vol.164
, pp. 1862-72
-
-
Karulin, A.Y.1
Hesse, M.D.2
Tary-Lehmann, M.3
Lehmann, P.V.4
-
32
-
-
0029131491
-
Interleukin-4 and interleukin-5 are rarely co-expressed by human T cells
-
10.1002/eji.1830250843 1:CAS:528:DyaK2MXns1KqtLc%3D 7664804
-
T Jung U Schauer C Rieger K Wagner K Einsle C Neumann C Heusser 1995 Interleukin-4 and interleukin-5 are rarely co-expressed by human T cells Eur J Immunol 25 2413 6 10.1002/eji.1830250843 1:CAS:528:DyaK2MXns1KqtLc%3D 7664804
-
(1995)
Eur J Immunol
, vol.25
, pp. 2413-6
-
-
Jung, T.1
Schauer, U.2
Rieger, C.3
Wagner, K.4
Einsle, K.5
Neumann, C.6
Heusser, C.7
-
33
-
-
0029057855
-
Evidence for the stochastic acquisition of cytokine profile by CD4+ T cells activated in a T helper type 2-like response in vivo
-
10.1002/eji.1830250506 1:CAS:528:DyaK2MXmtV2ht70%3D 7774620
-
A Kelso P Groves AB Troutt K Francis 1995 Evidence for the stochastic acquisition of cytokine profile by CD4+ T cells activated in a T helper type 2-like response in vivo Eur J Immunol 25 1168 75 10.1002/eji.1830250506 1:CAS:528:DyaK2MXmtV2ht70%3D 7774620
-
(1995)
Eur J Immunol
, vol.25
, pp. 1168-75
-
-
Kelso, A.1
Groves, P.2
Troutt, A.B.3
Francis, K.4
-
34
-
-
34250303350
-
H1 cells define a correlate of vaccine-mediated protection against Leishmania major
-
DOI 10.1038/nm1592, PII NM1592
-
PA Darrah DT Patel PM De Luca RW Lindsay DF Davey BJ Flynn ST Hoff P Andersen SG Reed SL Morris M Roederer RA Seder 2007 Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major Nat Med 13 843 50 10.1038/nm1592 1:CAS:528:DC%2BD2sXnsFWmtr0%3D 17558415 (Pubitemid 47038186)
-
(2007)
Nature Medicine
, vol.13
, Issue.7
, pp. 843-850
-
-
Darrah, P.A.1
Patel, D.T.2
De Luca, P.M.3
Lindsay, R.W.B.4
Davey, D.F.5
Flynn, B.J.6
Hoff, S.T.7
Andersen, P.8
Reed, S.G.9
Morris, S.L.10
Roederer, M.11
Seder, R.A.12
-
35
-
-
33646686040
-
+ T cells
-
DOI 10.1182/blood-2005-12-4818
-
MR Betts MC Nason SM West SC De Rosa SA Migueles J Abraham MM Lederman JM Benito PA Goepfert M Connors M Roederer RA Koup 2006 HIV non-progressors preferentially maintain highly functional HIV-specific CD8+ T cells Blood 107 4781 9 10.1182/blood-2005-12-4818 1:CAS:528:DC%2BD28XlvFCgtrg%3D 16467198 (Pubitemid 43882629)
-
(2006)
Blood
, vol.107
, Issue.12
, pp. 4781-4789
-
-
Betts, M.R.1
Nason, M.C.2
West, S.M.3
De Rosa, S.C.4
Migueles, S.A.5
Abraham, J.6
Lederman, M.M.7
Benito, J.M.8
Goepfert, P.A.9
Connors, M.10
Roederer, M.11
Koup, R.A.12
-
36
-
-
10744223436
-
A Fluorospot assay to detect single T lymphocytes simultaneously producing multiple cytokines
-
DOI 10.1016/j.jim.2003.08.013
-
A Gazagne E Claret J Wijdenes H Yssel F Bousquet E Levy P Vielh F Scotte TL Goupil WH Fridman E Tartour 2003 A Fluorospot assay to detect single T lymphocytes simultaneously producing multiple cytokines J Immunol Methods 283 91 8 10.1016/j.jim.2003.08.013 1:CAS:528:DC%2BD3sXptlOlurs%3D 14659902 (Pubitemid 37501061)
-
(2003)
Journal of Immunological Methods
, vol.283
, Issue.1-2
, pp. 91-98
-
-
Gazagne, A.1
Claret, E.2
Wijdenes, J.3
Yssel, H.4
Bousquet, F.5
Levy, E.6
Vielh, P.7
Scotte, F.8
Goupil, T.L.9
Fridman, W.H.10
Tartour, E.11
-
37
-
-
25144438916
-
The balance between influenza- and RSV-specific CD4 T cells secreting IL-10 or IFNγ in young and healthy-elderly subjects
-
DOI 10.1016/j.mad.2005.06.011, PII S0047637405001521
-
FE Lee EE Walsh AR Falsey N Liu D Liu A Divekar JE Snyder-Cappione TR Mosmann 2005 The balance between influenza- and RSV-specific CD4 T cells secreting IL-10 or IFNgamma in young and healthy-elderly subjects Mech Ageing Dev 126 1223 9 10.1016/j.mad.2005.06.011 1:CAS:528:DC%2BD2MXhtVKjs7jL 16098562 (Pubitemid 41356524)
-
(2005)
Mechanisms of Ageing and Development
, vol.126
, Issue.11
, pp. 1223-1229
-
-
Lee, F.E.-H.1
Walsh, E.E.2
Falsey, A.R.3
Liu, N.4
Liu, D.5
Divekar, A.6
Snyder-Cappione, J.E.7
Mosmann, T.R.8
-
38
-
-
49949106240
-
Automated analysis of two- and three-color fluorescent Elispot (Fluorospot) assays for cytokine secretion
-
10.1016/j.cmpb.2008.06.002 18644656
-
JA Rebhahn C Bishop AA Divekar K Jiminez-Garcia JJ Kobie FE Lee GM Maupin JE Snyder-Cappione DM Zaiss TR Mosmann 2008 Automated analysis of two- and three-color fluorescent Elispot (Fluorospot) assays for cytokine secretion Comput Methods Programs Biomed 92 54 65 10.1016/j.cmpb.2008.06.002 18644656
-
(2008)
Comput Methods Programs Biomed
, vol.92
, pp. 54-65
-
-
Rebhahn, J.A.1
Bishop, C.2
Divekar, A.A.3
Jiminez-Garcia, K.4
Kobie, J.J.5
Lee, F.E.6
Maupin, G.M.7
Snyder-Cappione, J.E.8
Zaiss, D.M.9
Mosmann, T.R.10
-
39
-
-
33947685007
-
Collagen distribution and expression of collagen-binding alpha1beta1 (VLA-1) and alpha2beta1 (VLA-2) integrins on CD4 and CD8 T cells during influenza infection
-
1:CAS:528:DC%2BD2sXjt1Wks7w%3D 17372009
-
M Richter SJ Ray TJ Chapman SJ Austin J Rebhahn TR Mosmann H Gardner V Kotelianski AR de Fougerolles DJ Topham 2007 Collagen distribution and expression of collagen-binding alpha1beta1 (VLA-1) and alpha2beta1 (VLA-2) integrins on CD4 and CD8 T cells during influenza infection J Immunol 178 4506 16 1:CAS:528:DC%2BD2sXjt1Wks7w%3D 17372009
-
(2007)
J Immunol
, vol.178
, pp. 4506-16
-
-
Richter, M.1
Ray, S.J.2
Chapman, T.J.3
Austin, S.J.4
Rebhahn, J.5
Mosmann, T.R.6
Gardner, H.7
Kotelianski, V.8
De Fougerolles, A.R.9
Topham, D.J.10
-
40
-
-
0028960201
-
Analysis and sorting of live cells according to secreted molecules, relocated to a cell-surface affinity matrix
-
10.1073/pnas.92.6.1921 1:CAS:528:DyaK2MXksVCqs74%3D 7892200
-
R Manz M Assenmacher E Pfluger S Miltenyi A Radbruch 1995 Analysis and sorting of live cells according to secreted molecules, relocated to a cell-surface affinity matrix Proc Natl Acad Sci USA 92 1921 5 10.1073/pnas.92.6.1921 1:CAS:528:DyaK2MXksVCqs74%3D 7892200
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1921-5
-
-
Manz, R.1
Assenmacher, M.2
Pfluger, E.3
Miltenyi, S.4
Radbruch, A.5
-
41
-
-
34347232370
-
Intracellular cytokine optimization and standard operating procedure
-
10.1038/nprot.2006.268 1:CAS:528:DC%2BD28Xht1eitL%2FP 17406442
-
L Lamoreaux M Roederer R Koup 2006 Intracellular cytokine optimization and standard operating procedure Nat Protoc 1 1507 16 10.1038/nprot.2006.268 1:CAS:528:DC%2BD28Xht1eitL%2FP 17406442
-
(2006)
Nat Protoc
, vol.1
, pp. 1507-16
-
-
Lamoreaux, L.1
Roederer, M.2
Koup, R.3
-
42
-
-
1242306183
-
CD28 costimulation enhances the sensitivity of the ELISPOT assay for detection of antigen-specific memory effector CD4 and CD8 cell populations in human diseases
-
DOI 10.1016/j.jim.2003.12.007
-
PA Ott BR Berner BA Herzog R Guerkov NL Yonkers I Durinovic-Bello M Tary-Lehmann PV Lehmann DD Anthony 2004 CD28 co-stimulation enhances the sensitivity of the ELISPOT assay for detection of antigen-specific memory effector CD4 and CD8 cell populations in human diseases J Immunol Methods 285 223 35 10.1016/j.jim.2003.12.007 1:CAS:528:DC%2BD2cXht1yks74%3D 14980436 (Pubitemid 38224564)
-
(2004)
Journal of Immunological Methods
, vol.285
, Issue.2
, pp. 223-235
-
-
Ott, P.A.1
Berner, B.R.2
Herzog, B.A.3
Guerkov, R.4
Yonkers, N.L.5
Durinovic-Bello, I.6
Tary-Lehmann, M.7
Lehmann, P.V.8
Anthony, D.D.9
-
43
-
-
0036887588
-
Enhanced ELISPOT detection of antigen-specific T cell responses from cryopreserved specimens with addition of both IL-7 and IL-15-the Amplispot assay
-
1:CAS:528:DC%2BD38XnvVOnsL0%3D 12379342
-
W Jennes L Kestens DF Nixon BL Shacklett 2002 Enhanced ELISPOT detection of antigen-specific T cell responses from cryopreserved specimens with addition of both IL-7 and IL-15-the Amplispot assay J Immunol Methods 270 99 108 1:CAS:528:DC%2BD38XnvVOnsL0%3D 12379342
-
(2002)
J Immunol Methods
, vol.270
, pp. 99-108
-
-
Jennes, W.1
Kestens, L.2
Nixon, D.F.3
Shacklett, B.L.4
-
44
-
-
21244465847
-
Simultaneous Th1-type cytokine expression is a signature of peritoneal CD4+ lymphocytes responding to infection with Listeria monocytogenes
-
1:CAS:528:DC%2BD2MXltlymsr4%3D 15972673
-
MM Freeman HK Ziegler 2005 Simultaneous Th1-type cytokine expression is a signature of peritoneal CD4+ lymphocytes responding to infection with Listeria monocytogenes J Immunol 175 394 403 1:CAS:528:DC%2BD2MXltlymsr4%3D 15972673
-
(2005)
J Immunol
, vol.175
, pp. 394-403
-
-
Freeman, M.M.1
Ziegler, H.K.2
-
45
-
-
0030846262
-
+ T cells
-
DOI 10.1084/jem.186.5.757
-
Y Itoh RN Germain 1997 Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells J Exp Med 186 757 66 10.1084/jem.186.5.757 1:CAS:528:DyaK2sXlvVeitL0%3D 9271591 (Pubitemid 27381540)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.5
, pp. 757-766
-
-
Itoh, Y.1
Germain, R.N.2
-
46
-
-
56349154943
-
Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
-
10.1038/ni.1659
-
M Veldhoen C Uyttenhove J van Snick H Helmby A Westendorf J Buer B Martin C Wilhelm B Stockinger 2008 Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset Nat Immunol 19 12 1341 1346 10.1038/ni.1659
-
(2008)
Nat Immunol
, vol.19
, Issue.12
, pp. 1341-1346
-
-
Veldhoen, M.1
Uyttenhove, C.2
Van Snick, J.3
Helmby, H.4
Westendorf, A.5
Buer, J.6
Martin, B.7
Wilhelm, C.8
Stockinger, B.9
-
47
-
-
0024408824
-
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
-
DOI 10.1084/jem.170.6.2081
-
DF Fiorentino MW Bond TR Mosmann 1989 Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones J Exp Med 170 2081 95 10.1084/jem.170.6.2081 1:CAS:528:DyaK3cXhtFKqtL0%3D 2531194 (Pubitemid 20010086)
-
(1989)
Journal of Experimental Medicine
, vol.170
, Issue.6
, pp. 2081-20095
-
-
Fiorentino, D.F.1
Bond, M.W.2
Mosmann, T.R.3
-
48
-
-
29244483404
-
IL-2 absorption affects IFN-γ and IL-5, but not IL-4 producing memory T cells in double color cytokine ELISPOT assays
-
DOI 10.1016/j.cellimm.2005.09.002, PII S000887490500198X
-
S Quast W Zhang C Shive D Kovalovski PA Ott BA Herzog BO Boehm M Tary-Lehmann AY Karulin PV Lehmann 2005 IL-2 absorption affects IFN-gamma and IL-5, but not IL-4 producing memory T cells in double color cytokine ELISPOT assays Cell Immunol 237 28 36 10.1016/j.cellimm.2005.09.002 1:CAS:528: DC%2BD2MXhtlGisbvM 16256965 (Pubitemid 41821079)
-
(2005)
Cellular Immunology
, vol.237
, Issue.1
, pp. 28-36
-
-
Quast, S.1
Zhang, W.2
Shive, C.3
Kovalovski, D.4
Ott, P.A.5
Herzog, B.A.6
Boehm, B.O.7
Tary-Lehmann, M.8
Karulin, A.Y.9
Lehmann, P.V.10
-
49
-
-
0025763807
-
IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells
-
1:CAS:528:DyaK3MXltleksLg%3D 1827484
-
DF Fiorentino A Zlotnik P Vieira TR Mosmann M Howard KW Moore A O'Garra 1991 IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells J Immunol 146 3444 51 1:CAS:528:DyaK3MXltleksLg%3D 1827484
-
(1991)
J Immunol
, vol.146
, pp. 3444-51
-
-
Fiorentino, D.F.1
Zlotnik, A.2
Vieira, P.3
Mosmann, T.R.4
Howard, M.5
Moore, K.W.6
O'Garra, A.7
-
50
-
-
33845713725
-
H2 cytokine enhancing resistance to nematodes
-
DOI 10.1126/science.1133715
-
DM Zaiss L Yang PR Shah JJ Kobie JF Urban TR Mosmann 2006 Amphiregulin, a TH2 cytokine enhancing resistance to nematodes Science 314 1746 10.1126/science.1133715 1:CAS:528:DC%2BD28XhtlSqtLnE 17170297 (Pubitemid 44969079)
-
(2006)
Science
, vol.314
, Issue.5806
, pp. 1746
-
-
Zaiss, D.M.1
Yang, L.2
Shah, P.R.3
Kobie, J.J.4
Urban, J.F.5
Mosmann, T.R.6
-
51
-
-
20444502955
-
PU.1 expression delineates heterogeneity in primary Th2 cells
-
DOI 10.1016/j.immuni.2005.03.016, PII S107476130500138X
-
HC Chang S Zhang VT Thieu RB Slee HA Bruns RN Laribee MJ Klemsz MH Kaplan 2005 PU.1 expression delineates heterogeneity in primary Th2 cells Immunity 22 693 703 10.1016/j.immuni.2005.03.016 1:CAS:528:DC%2BD2MXmtVartbY%3D 15963784 (Pubitemid 40814500)
-
(2005)
Immunity
, vol.22
, Issue.6
, pp. 693-703
-
-
Chang, H.-C.1
Zhang, S.2
Thieu, V.T.3
Slee, R.B.4
Bruns, H.A.5
Laribee, R.N.6
Klemsz, M.J.7
Kaplan, M.H.8
-
53
-
-
0027336689
-
Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages
-
10.1126/science.8097338 1:CAS:528:DyaK3sXitlajsLg%3D 8097338 see comments
-
CS Hsieh SE Macatonia CS Tripp SF Wolf A O'Garra KM Murphy 1993 Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages Science 260 547 9 10.1126/science.8097338 1:CAS:528: DyaK3sXitlajsLg%3D 8097338 see comments
-
(1993)
Science
, vol.260
, pp. 547-9
-
-
Hsieh, C.S.1
MacAtonia, S.E.2
Tripp, C.S.3
Wolf, S.F.4
O'Garra, A.5
Murphy, K.M.6
-
54
-
-
0026507228
-
Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones
-
1:CAS:528:DyaK38XisFekt7o%3D 1532000
-
E Maggi P Parronchi R Manetti C Simonelli MP Piccinni FS Rugiu M De Carli M Ricci S Romagnani 1992 Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones J Immunol 148 2142 7 1:CAS:528:DyaK38XisFekt7o%3D 1532000
-
(1992)
J Immunol
, vol.148
, pp. 2142-7
-
-
Maggi, E.1
Parronchi, P.2
Manetti, R.3
Simonelli, C.4
Piccinni, M.P.5
Rugiu, F.S.6
De Carli, M.7
Ricci, M.8
Romagnani, S.9
-
55
-
-
0025951644
-
Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype
-
1:CAS:528:DyaK38XltVWn 1680924
-
SL Swain G Huston S Tonkonogy A Weinberg 1991 Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype J Immunol 147 2991 3000 1:CAS:528:DyaK38XltVWn 1680924
-
(1991)
J Immunol
, vol.147
, pp. 2991-3000
-
-
Swain, S.L.1
Huston, G.2
Tonkonogy, S.3
Weinberg, A.4
-
56
-
-
0027409793
-
Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells
-
10.1084/jem.177.4.1199 1:CAS:528:DyaK3sXhsVGkt7o%3D 8096238
-
R Manetti P Parronchi MG Giudizi MP Piccinni E Maggi G Trinchieri S Romagnani 1993 Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells J Exp Med 177 1199 204 10.1084/jem.177.4.1199 1:CAS:528:DyaK3sXhsVGkt7o%3D 8096238
-
(1993)
J Exp Med
, vol.177
, pp. 1199-204
-
-
Manetti, R.1
Parronchi, P.2
Giudizi, M.G.3
Piccinni, M.P.4
Maggi, E.5
Trinchieri, G.6
Romagnani, S.7
-
57
-
-
0023782871
-
Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones
-
1:CAS:528:DyaL1cXkvFWjsr8%3D 2969394
-
X Paliard R l Malefijt H Yssel D Blanchard I Chretien J Abrams J de Vries H Spits 1988 Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones J Immunol 141 849 55 1:CAS:528: DyaL1cXkvFWjsr8%3D 2969394
-
(1988)
J Immunol
, vol.141
, pp. 849-55
-
-
Paliard, X.1
Malefijt R, L.2
Yssel, H.3
Blanchard, D.4
Chretien, I.5
Abrams, J.6
De Vries, J.7
Spits, H.8
-
58
-
-
0032103969
-
Generation, persistence, and modulation of Th0 effector cells: Role of autocrine IL-4 and IFN-gamma
-
1:CAS:528:DyaK1cXjt1GntL8%3D 9605125
-
KT Miner M Croft 1998 Generation, persistence, and modulation of Th0 effector cells: role of autocrine IL-4 and IFN-gamma J Immunol 160 5280 7 1:CAS:528:DyaK1cXjt1GntL8%3D 9605125
-
(1998)
J Immunol
, vol.160
, pp. 5280-7
-
-
Miner, K.T.1
Croft, M.2
-
59
-
-
0030704726
-
+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
DOI 10.1038/39614
-
H Groux A O'Garra M Bigler M Rouleau S Antonenko JE de Vries MG Roncarolo 1997 A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis Nature 389 737 42 10.1038/39614 1:CAS:528:DyaK2sXmvVSgtb0%3D 9338786 (Pubitemid 27458961)
-
(1997)
Nature
, vol.389
, Issue.6652
, pp. 737-742
-
-
Groux, H.1
O'Garra, A.2
Bigler, M.3
Rouleau, M.4
Antonenko, S.5
De Vries, J.E.6
Roncarolo, M.G.7
-
60
-
-
34447503805
-
H17 and regulatory T cell differentiation mediated by retinoic acid
-
DOI 10.1126/science.1145697
-
D Mucida Y Park G Kim O Turovskaya I Scott M Kronenberg H Cheroutre 2007 Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid Science 317 256 60 10.1126/science.1145697 1:CAS:528:DC%2BD2sXnsFaqt78%3D 17569825 (Pubitemid 47076203)
-
(2007)
Science
, vol.317
, Issue.5835
, pp. 256-260
-
-
Mucida, D.1
Park, Y.2
Kim, G.3
Turovskaya, O.4
Scott, I.5
Kronenberg, M.6
Cheroutre, H.7
|