Direct injection liquid chromatography/positive ion electrospray ionization mass spectrometric quantification of methotrexate, folinic acid, folic acid and ondansetron in human serum

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 30, 2009, Pages 3850-3856

  Koufopantelis, Panagiotis ^a   Georgakakou, Sophia ^a   Kazanis, Michael ^a   Giaginis, Costas ^a   Margeli, Alexandra ^b   Papargiri, Sophia ^b   Panderi, Irene ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b IASO GENERAL HOSPITAL   (Greece)

Author keywords

Folic acid; Folinic acid; Human serum; Liquid chromatography mass spectrometry; Methotrexate; Ondansetron

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ALFUZOSIN; ANALYTES; ANALYTICAL COLUMNS; CLINICAL STUDY; CONCENTRATION RANGES; DIRECT INJECTION; ELECTROSPRAY IONIZATION INTERFACE; FOLIC ACIDS; FOLINIC ACID; HUMAN SERUM; INTERNAL STANDARDS; ION ELECTROSPRAY; ION ELECTROSPRAY IONIZATION; IONIZATION MODES; ISOCRATIC ELUTION; LC/ESI-MS; LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY; MOBILE PHASE; RUNTIMES; SELECTED ION MONITORING; SERUM SAMPLES;

ACETONITRILE; BODY FLUIDS; ELECTROSPRAY IONIZATION; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONIZATION; IONS; LIQUIDS; MASS SPECTROMETERS; ORGANIC ACIDS; PARTICLE DETECTORS; PHASE INTERFACES; SPECTROMETRY;

FORMIC ACID;

ACETONITRILE; ALFUZOSIN; FOLIC ACID; FOLINIC ACID; FORMIC ACID; METHOTREXATE; ONDANSETRON; WATER;

ACCURACY; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; CHILD; CLINICAL ARTICLE; DRUG BLOOD LEVEL; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; HUMAN; ION MONITORING; LIQUID CHROMATOGRAPHY; PRECIPITATION; PRIORITY JOURNAL; QUANTITATIVE ASSAY;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; CHROMATOGRAPHY, LIQUID; FEMALE; FOLIC ACID; HUMANS; INFANT; LEUCOVORIN; MALE; METHOTREXATE; ONDANSETRON; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 72049112339     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.09.034     Document Type: Article

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