Highly sensitive high-performance liquid chromatographic assay for methotrexate in the presence and absence of anti-methotrexate antibody fragments in rat and mouse plasma

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 736, Issue 1-2, 1999, Pages 191-199

  Lobo, Evelyn D ^a   Balthasar, Joseph P ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

Anti methotrexate antibody fragments; Methotrexate

Indexed keywords

DRUG ANTIBODY; METHOTREXATE;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DERIVATIZATION; DRUG CLEARANCE; DRUG DETERMINATION; DRUG DISPOSITION; DRUG ELIMINATION; DRUG HALF LIFE; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; RAT; ULTRAFILTRATION;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; IMMUNOGLOBULIN FRAGMENTS; KINETICS; MALE; METHOTREXATE; MICE; RATS; RATS, SPRAGUE-DAWLEY; SULFITES;

EID: 0032748392     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(99)00460-0     Document Type: Article

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