Folic acid supplements are good (not bad) for rheumatoid arthritis patients treated with lowdose methotrexate

American Journal of Clinical Nutrition

Volumn 88, Issue 2, 2008, Pages 479-480

  Baggott, Joseph E ^a   Morgan, Sarah L ^a  

^a Univ of Alabama School of Dentistry   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FOLIC ACID; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT;

CHRONIC DRUG ADMINISTRATION; CYTOPENIA; DIET SUPPLEMENTATION; DRUG EFFICACY; GOLD STANDARD; HUMAN; LETTER; LOW DRUG DOSE; RHEUMATOID ARTHRITIS; SIDE EFFECT; STOMATITIS;

EID: 49449095496     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/88.2.479     Document Type: Letter

References (10)

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2. Morgan SL, Baggott JE, Vaughn WH, et al. Supplementation with folic acid during methotrexate therapy of rheumatoid arthritis: results from a double-blind, placebo-controlled trial. Ann Intern Med 1994;121:833-41.
3. Alarcón G, Tracy I, Blackburn W. Methotrexate in rheumatoid arthritis: toxic effects as the major factor in limiting long-term treatment. Arthritis Rheum 1989;32:671-6.
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9. Khanna D, Park GS, Paulus HE, et al. Reduction of the efficacy of methotrexate by the use of folic acid: post hoc analysis from two randomized controlled studies. Arthritis Rheum 2005;52:3030-8.
10. Morgan SL, Baggott JE, Alarcón GS. Effect of folic acid supplementation on the efficacy of methotrexate treatment in rheumatoid arthritis: comment on the article by Khanna et al. Arthritis Rheum 2006;54:1708-9.