On-line precolumn derivatization for HPLC determination of methotrexate using a column packed oxidant

Biomedical Chromatography

Volumn 11, Issue 1, 1997, Pages 42-46

  Emara, Samy ^a   Razee, Saied ^b   Khedr, Alaa ^a   Masujima, Tsutomu ^b  

^a University of Assiut   (Egypt)

^b HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CERIUM COMPOUNDS; CHROMATOGRAPHIC ANALYSIS; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANALYTICAL COLUMNS; CHROMATOGRAPHIC SYSTEMS; FLUORIMETRIC DETECTION; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC METHODS; OXIDATIVE CLEAVAGES; PHOSPHATE BUFFERS; PLASMA SAMPLES; PRE-COLUMN DERIVATISATION; PROTEIN PRECIPITATION; SOLVENT PURIFICATION;

OXIDANTS;

ACETONITRILE; ANTINEOPLASTIC AGENT; BUFFER; CERIUM; METHOTREXATE; PHOSPHATE; SOLVENT;

ACCURACY; ARTICLE; BLOOD SAMPLING; DERIVATIZATION; DRUG BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PRECIPITATION; PURIFICATION; VARIANCE;

EID: 0031049373     PISSN: 02693879     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0801(199701)11:1<42::AID-BMC621>3.0.CO;2-F     Document Type: Article

References (19)

1. Albertioni, F., Pettersson, B., Beck, O., Rask, C., Seideman, P. and Peterson, C. (1995). J. Chromatogr. B. 665, 163.
2. Assadullahi, P. T., Dagli, E. and Warner, J. O. (1991). J. Chromatogr. 565, 349.
3. Belz, S., Frickel, C., Wolfrom, C., Nau, H. and Henze, G. (1994). J. Chromatogr. B. 661, 109.
4. Brimmel, P. A. and Sams, D. J. (1987). J. Chromatogr. 413, 320.
5. Buice, R. G., Evans, W. E., Karas, J., Nicholas, C. A., Sidhu, P., Straughn, A. B., Meyer, M. C. and Crom, W. R. (1980). Clin. Chem. 26, 1092.
6. Deen, W. M., Levy, P. E., Wei, J. and Partridge, R. D. (1981). Anal. Biochem. 144, 355.
7. Emara, S., Razee, S., El-Shorbagy, A. and Masujima, T. (1996). The Analyst. 121, 183.
8. Falk, L. C., Clark, D. R., Kalman, S. M. and Long, T. F. (1976). Clin. Chem. 22, 785.
9. Kubo, H., Umiguchi, Y., Fukumoto, M. and Kinoshita, T. (1992). Anal. Sci. 8, 789.
10. Mendel, J., Sarek, L. J. and Hvidberg, E. F. (1976). Clin. Chem. 22, 813.
11. Nelson, J. A., Harris, B. A., Decker, W. J. and Farquhar, D. (1977). Cancer Res. 37, 3970.
12. Okuda, T., Motohashi, M., Aoki, I. and Yashiki, T. (1994). J. Chromatogr. B. 662, 79.
13. Roach, M. C., Gopzel, P. and Zare, R. N. (1988). J. Chromatogr. 426, 129.
14. Šalamoun, J. and František, J. (1986). J. Chromatogr. 378, 173.
15. Šalamoun, J., Smrz, M., Kiss, F. and Salamounova, A. (1987). J. Chromatogr. 419, 213.
16. Steuijt, K. V. and Sonneveld, P. (1987). J. Chromatogr. 422, 328.
17. Stout, M., Ravindranath, Y. and Kauffman, R. (1985). J. Chromatogr. 342, 424.
18. Suzuki, T., Hashimoto, H. and Ichinose, N. (1995). Fresenius. J. Anal. Chem. 351, 806.
19. United States Pharmacopeia XXII Revision, National Formulary XVII (1990). United States Pharmacopeial Convention, Rockville, MD. pp. 885-886.