GDF5 and BMP2 inhibit apoptosis via activation of BMPR2 and subsequent stabilization of XIAP

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1793, Issue 12, 2009, Pages 1819-1827

  Liu, Zhipei ^a   Shen, Jia ^a   Pu, Kui ^c   Katus, Hugo A ^b   Plöger, Frank ^d   Tiefenbacher, Christiane P ^b   Chen, Xiaobo ^a,b   Braun, Thomas ^a  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c Chinese PLA 254 Hospital   (China)

^d Biopharm GmbH   (Germany)

Author keywords

Apoptosis; BMP2; BMPR2; GDF5; Ubiquitin; XIAP

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; CASPASE; GROWTH DIFFERENTIATION FACTOR 5; MITOGEN ACTIVATED PROTEIN KINASE; SMAD PROTEIN; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; ENZYME BINDING; ENZYME INACTIVATION; FIBROBLAST CULTURE; GENE MUTATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; UBIQUITINATION; UMBILICAL VEIN;

ANIMALS; APOPTOSIS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; CELL LINE; CELL PROLIFERATION; EMBRYO, MAMMALIAN; FIBROBLASTS; GROWTH DIFFERENTIATION FACTOR 5; HUMANS; HYPERTENSION, PULMONARY; MICE; MUSCLE, SMOOTH, VASCULAR; MUTATION; MYOCYTES, SMOOTH MUSCLE; PROTEIN STABILITY; UBIQUITINATION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 71749120773     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2009.09.012     Document Type: Article

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