BMP-2 prevents apoptosis of the N1511 chondrocytic cell line through PI3K/Akt-mediated NF-κB activation

Journal of Bone and Mineral Metabolism

Volumn 23, Issue 6, 2005, Pages 411-419

  Sugimori, Kazuhito ^a   Matsui, Koshi ^a   Motomura, Hiraku ^a   Tokoro, Takashi ^a   Wang, Juyong ^a   Higa, Susumu ^a   Kimura, Tomoatsu ^a   Kitajima, Isao ^a  

^a TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; Bone morphogenetic protein 2; Chondrocyte; Nuclear factor B

Indexed keywords

CASPASE 3; CASPASE 9; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NOGGIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL XL; PROTEIN KINASE B; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; SERINE; SYNAPTOTAGMIN; WORTMANNIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARTILAGE CELL; CELL LINE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REACTION TIME; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; APOPTOSIS; BCL-X PROTEIN; BONE MORPHOGENETIC PROTEINS; CARRIER PROTEINS; CASPASE 3; CASPASE 9; CASPASES; CELL LINE; CHONDROCYTES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; MICE; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA;

EID: 27644484777     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00774-005-0622-7     Document Type: Article

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