Pivotal role of the C-terminal DW-motif in mediating inhibition of pyruvate dehydrogenase kinase 2 by dichloroacetate

Journal of Biological Chemistry

Volumn 284, Issue 49, 2009, Pages 34458-34467

  Li, Jun ^a   Kato, Masato ^a   Chuang, David T ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; DISEASES; ENZYMES; SIGNALING;

BINDING AFFINITIES; DICHLOROACETATE; OPEN CONFORMATION; OVER-EXPRESSION; PYRUVATE DEHYDROGENASE COMPLEX; PYRUVATE DEHYDROGENASE KINASE; RESIDUAL ACTIVITY; SIGNALING NETWORKS;

BINDING SITES;

PYRUVATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE KINASE 2;

ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; GENETIC VARIABILITY; HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN PURIFICATION; WILD TYPE;

EID: 71749096219     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.065557     Document Type: Article

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