New R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans as KATP channel openers: Modulation of the 4-position

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 22, 2009, Pages 7723-7731

  Florence, Xavier ^a   Sebille, Sophie ^a   Tullio, Pascal de ^a   Lebrun, Philippe ^b   Pirotte, Bernard ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Benzopyran derivatives; Cromakalim analogues; KATP channels; Potassium channel openers

Indexed keywords

6 CHLORO 4 (4 CYANOPHENYLAMINOTHIOCARBONYLAMINO) 3,4 DIHYDRO 2,2 DIMETHYL 2H 1 BENZOPYRAN; BENZOPYRAN DERIVATIVE; CROMAKALIM; DIAZOXIDE; PINACIDIL; POTASSIUM CHANNEL STIMULATING AGENT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET; RAT; STRUCTURE ACTIVITY RELATION; VASCULAR RING;

ADENOSINE TRIPHOSPHATE; ANIMALS; BENZOPYRANS; CROMAKALIM; DIAZOXIDE; ISLETS OF LANGERHANS; MUSCLE, SMOOTH, VASCULAR; PINACIDIL; POTASSIUM CHANNELS; RATS; RATS, WISTAR; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; VASODILATOR AGENTS;

RATTUS;

EID: 71749086139     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.09.041     Document Type: Article

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