SCOPUS 정보 검색 플랫폼

Volumn 16, Issue 1, 2010, Pages 49-59

Insight into ligand selectivity in HCV NS5B polymerase: Molecular dynamics simulations, free energy decomposition and docking

(3) Li, Tong a Froeyen, Matheus a Herdewijn, Piet a

a REGA INSTITUTE FOR MEDICAL RESEARCH (Belgium)

Author keywords

Cross docking; Free energy decomposition; HCV NS5B Polymerase; MM GBSA; Molecular dynamics; Structure based drug design

Indexed keywords

ARGININE; CYSTEINE; HEPATITIS C VIRUS POLYMERASE NS5B; METHIONINE; PROLINE; TYROSINE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; BINDING SITE; COMPLEX FORMATION; DECOMPOSITION; ENERGY DECOMPOSITION; ENZYME SPECIFICITY; HYDROGEN BOND; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; SIMULATION;

BINDING SITES; DRUG DESIGN; ENZYME INHIBITORS; HEPACIVIRUS; HUMANS; HYDROGEN BONDING; LIGANDS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS;

EID: 71349084497 PISSN: 16102940 EISSN: 09485023 Source Type: Journal
DOI: 10.1007/s00894-009-0519-9 Document Type: Article

Times cited : (22)

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