-
1
-
-
0036191805
-
Lymphocytic choriomeningitis virus and immunology
-
Zingkernagel R.M. Lymphocytic choriomeningitis virus and immunology. Curr Top Microbiol Immunol 263 (2002) 1-5
-
(2002)
Curr Top Microbiol Immunol
, vol.263
, pp. 1-5
-
-
Zingkernagel, R.M.1
-
2
-
-
36549013250
-
Defective T helper response of hepatocyte-stimulated CD4 T cells impairs antiviral CD8 response and viral clearance
-
Wiegard C., Wolint P., Frenzel C., Cheruti U., Schmitt E., Oxenius A., et al. Defective T helper response of hepatocyte-stimulated CD4 T cells impairs antiviral CD8 response and viral clearance. Gastroenterology 133 (2007) 2010-2018
-
(2007)
Gastroenterology
, vol.133
, pp. 2010-2018
-
-
Wiegard, C.1
Wolint, P.2
Frenzel, C.3
Cheruti, U.4
Schmitt, E.5
Oxenius, A.6
-
3
-
-
41149160165
-
Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy
-
Rehr M., Cahenzli J., Haas A., Price D.A., Gostick E., Huber M., et al. Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy. J Virol 82 (2008) 3391-3404
-
(2008)
J Virol
, vol.82
, pp. 3391-3404
-
-
Rehr, M.1
Cahenzli, J.2
Haas, A.3
Price, D.A.4
Gostick, E.5
Huber, M.6
-
4
-
-
34248399247
-
Impaired NFAT nuclear translocation result in split exhaustion of virus-specific CD8+ T cell functions during chronic viral infection
-
Agnellini P., Wolint P., Rehr M., Cahenzli J., Karrer U., and Oxenius A. Impaired NFAT nuclear translocation result in split exhaustion of virus-specific CD8+ T cell functions during chronic viral infection. Proc Natl Acad Sci USA 104 (2007) 4565-4570
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 4565-4570
-
-
Agnellini, P.1
Wolint, P.2
Rehr, M.3
Cahenzli, J.4
Karrer, U.5
Oxenius, A.6
-
5
-
-
46749155479
-
Aggravation of viral hepatitis by platelet-derived serotonin
-
Lang P.A., Contaldo C., Georgiev P., El-Badry A.M., Recher M., Kurrer M., et al. Aggravation of viral hepatitis by platelet-derived serotonin. Nat Med 14 (2008) 756-761
-
(2008)
Nat Med
, vol.14
, pp. 756-761
-
-
Lang, P.A.1
Contaldo, C.2
Georgiev, P.3
El-Badry, A.M.4
Recher, M.5
Kurrer, M.6
-
6
-
-
33746365086
-
The lifestyle of naturally occurring CD4+ Cd25* foxp3* regulatory T cells
-
Shevach E.M., DiPaolo R.A., Andersson J., Zhao D.M., Stephens G.L., and Thronton A.M. The lifestyle of naturally occurring CD4+ Cd25* foxp3* regulatory T cells. Immunol Rev 212 (2006) 60-73
-
(2006)
Immunol Rev
, vol.212
, pp. 60-73
-
-
Shevach, E.M.1
DiPaolo, R.A.2
Andersson, J.3
Zhao, D.M.4
Stephens, G.L.5
Thronton, A.M.6
-
7
-
-
58849112222
-
Cutting edge: antigen-specific TGF beta-induced regulatory T cells suppress Th17-mediated autoimmune disease
-
Huter E.N., Stummvoll G.H., DiPaolo R.J., Glass D.D., and Shevach E.M. Cutting edge: antigen-specific TGF beta-induced regulatory T cells suppress Th17-mediated autoimmune disease. J Immunol 181 (2008) 8209-8213
-
(2008)
J Immunol
, vol.181
, pp. 8209-8213
-
-
Huter, E.N.1
Stummvoll, G.H.2
DiPaolo, R.J.3
Glass, D.D.4
Shevach, E.M.5
-
8
-
-
56349156910
-
Lymphocyte recruitment to the liver: molecular insights into the pathogenesis of liver injury and hepatitis
-
Shetty S., Lalor P.F., and Adams D.H. Lymphocyte recruitment to the liver: molecular insights into the pathogenesis of liver injury and hepatitis. Toxicology 254 (2008) 134-146
-
(2008)
Toxicology
, vol.254
, pp. 134-146
-
-
Shetty, S.1
Lalor, P.F.2
Adams, D.H.3
-
9
-
-
35948947428
-
Immune-mediated liver injury
-
Eksteen B., Afford S.C., Wigmore S.J., Holt A.P., and Adams D.H. Immune-mediated liver injury. Semin Liver Dis 27 (2007) 351-366
-
(2007)
Semin Liver Dis
, vol.27
, pp. 351-366
-
-
Eksteen, B.1
Afford, S.C.2
Wigmore, S.J.3
Holt, A.P.4
Adams, D.H.5
-
10
-
-
58649089811
-
Liver myofibroblasts regulate infiltration and positioning of lymphocytes in human liver
-
Holt A.P., Haughton E.L., Lalor P.F., Filer A., Buckley C.D., and Adams D.H. Liver myofibroblasts regulate infiltration and positioning of lymphocytes in human liver. Gastroenterology 136 (2009) 705-714
-
(2009)
Gastroenterology
, vol.136
, pp. 705-714
-
-
Holt, A.P.1
Haughton, E.L.2
Lalor, P.F.3
Filer, A.4
Buckley, C.D.5
Adams, D.H.6
-
11
-
-
41949104796
-
Hepatic NKT cells: friend or foe?
-
Swain M.G. Hepatic NKT cells: friend or foe?. Clin Sci (Lond) 114 (2008) 457-466
-
(2008)
Clin Sci (Lond)
, vol.114
, pp. 457-466
-
-
Swain, M.G.1
-
12
-
-
65449152565
-
Natural killer T cells regulate the homing of chemokine CXC receptor 3-positive regulatory T cells to the liver in mice
-
Santodomingo-Garzon T., Han J., Le T., Yang Y., and Swain M.G. Natural killer T cells regulate the homing of chemokine CXC receptor 3-positive regulatory T cells to the liver in mice. Hepatology 49 (2009) 1267-1276
-
(2009)
Hepatology
, vol.49
, pp. 1267-1276
-
-
Santodomingo-Garzon, T.1
Han, J.2
Le, T.3
Yang, Y.4
Swain, M.G.5
-
14
-
-
0029067106
-
Peripheral deletion of autoreactive CD8+ T cells in transgenic mice expressing H-2Kb in the liver
-
Bertolino P., Heath W.R., Hardy C.L., Morahan G., and Miller J.F. Peripheral deletion of autoreactive CD8+ T cells in transgenic mice expressing H-2Kb in the liver. Eur J Immunol 25 (1995) 1932-1942
-
(1995)
Eur J Immunol
, vol.25
, pp. 1932-1942
-
-
Bertolino, P.1
Heath, W.R.2
Hardy, C.L.3
Morahan, G.4
Miller, J.F.5
-
15
-
-
4944245002
-
The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity
-
Bowen D.G., Zen M., Holz L., Davis T., McCaughan G.W., and Bertolino P. The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity. J Clin Invest 114 (2004) 701-712
-
(2004)
J Clin Invest
, vol.114
, pp. 701-712
-
-
Bowen, D.G.1
Zen, M.2
Holz, L.3
Davis, T.4
McCaughan, G.W.5
Bertolino, P.6
-
16
-
-
0035423594
-
Neighborhood politics: the immunoregulatory function of organ-resident liver endothelial cells
-
Knolle P.A., and Limmer A. Neighborhood politics: the immunoregulatory function of organ-resident liver endothelial cells. Trends Immunol 22 (2001) 432-437
-
(2001)
Trends Immunol
, vol.22
, pp. 432-437
-
-
Knolle, P.A.1
Limmer, A.2
-
17
-
-
44849083915
-
Liver sinusoidal endothelial cells veto CD8 T cell activation by antigen-presenting dendritic cells
-
Schildberg F.A., Hegenbarth S.I., Schumak B., Scholz K., Limmer A., and Knolle P.A. Liver sinusoidal endothelial cells veto CD8 T cell activation by antigen-presenting dendritic cells. Eur J Immunol 38 (2008) 957-967
-
(2008)
Eur J Immunol
, vol.38
, pp. 957-967
-
-
Schildberg, F.A.1
Hegenbarth, S.I.2
Schumak, B.3
Scholz, K.4
Limmer, A.5
Knolle, P.A.6
-
18
-
-
37049003544
-
Kupffer cell heterogeneity: functional properties of bone marrow derived and sessile hepatic macrophages
-
Klein I., Cornejo J.C., Polakos N.K., John B., Wuensch S.A., Topham D.J., et al. Kupffer cell heterogeneity: functional properties of bone marrow derived and sessile hepatic macrophages. Blood 110 (2007) 4077-4085
-
(2007)
Blood
, vol.110
, pp. 4077-4085
-
-
Klein, I.1
Cornejo, J.C.2
Polakos, N.K.3
John, B.4
Wuensch, S.A.5
Topham, D.J.6
-
19
-
-
0029978748
-
Antigen-presenting function and B7 expression of murine sinusoidal endothelial cells and Kupffer cells
-
Lohse A.W., Knolle P., Bilo K., Uhrig A., Waldmann C., Ibe M., et al. Antigen-presenting function and B7 expression of murine sinusoidal endothelial cells and Kupffer cells. Gastroenterology 110 (1996) 1175-1181
-
(1996)
Gastroenterology
, vol.110
, pp. 1175-1181
-
-
Lohse, A.W.1
Knolle, P.2
Bilo, K.3
Uhrig, A.4
Waldmann, C.5
Ibe, M.6
-
20
-
-
0033002962
-
Induction of cytokine production in naive CD4(+) T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells
-
Knolle P.A., Schmitt E., Jin S., Germann T., Duchmann R., Hegenbarth S., et al. Induction of cytokine production in naive CD4(+) T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells. Gastroenterology 116 (1999) 1428-1440
-
(1999)
Gastroenterology
, vol.116
, pp. 1428-1440
-
-
Knolle, P.A.1
Schmitt, E.2
Jin, S.3
Germann, T.4
Duchmann, R.5
Hegenbarth, S.6
-
21
-
-
55849093638
-
Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs
-
Lüth S., Huber S., Schramm C., Buch T., Zander S., Stadelmann C., et al. Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs. J Clin Invest 118 (2008) 3403-3410
-
(2008)
J Clin Invest
, vol.118
, pp. 3403-3410
-
-
Lüth, S.1
Huber, S.2
Schramm, C.3
Buch, T.4
Zander, S.5
Stadelmann, C.6
-
22
-
-
21344466070
-
Murine liver antigen presenting cells control suppressor activity of CD4+CD25+ regulatory T cells
-
Wiegard C., Frenzel C., Herkel J., Kallen K.J., Schmitt E., and Lohse A.W. Murine liver antigen presenting cells control suppressor activity of CD4+CD25+ regulatory T cells. Hepatology 42 (2005) 193-199
-
(2005)
Hepatology
, vol.42
, pp. 193-199
-
-
Wiegard, C.1
Frenzel, C.2
Herkel, J.3
Kallen, K.J.4
Schmitt, E.5
Lohse, A.W.6
-
23
-
-
0037137532
-
The role of cytotoxic T cells and cytokines in the control of hepatitis B virus infection
-
Guidotti L.G. The role of cytotoxic T cells and cytokines in the control of hepatitis B virus infection. Vaccine 20 suppl. 4 (2002) A80-A82
-
(2002)
Vaccine
, vol.20
, Issue.SUPPL. 4
-
-
Guidotti, L.G.1
-
24
-
-
33947095580
-
HBV pathogenesis in animal models: recent advances on the role of platelets
-
Iannacone M., Sitia G., Ruggeri Z.M., and Guidotti L.G. HBV pathogenesis in animal models: recent advances on the role of platelets. J Hepatol 46 (2007) 719-726
-
(2007)
J Hepatol
, vol.46
, pp. 719-726
-
-
Iannacone, M.1
Sitia, G.2
Ruggeri, Z.M.3
Guidotti, L.G.4
-
25
-
-
30744437415
-
Platelets mediate cytotoxic T lymphocyte-induced liver damage
-
Iannacone M., Sitia G., Isogawa M., Marchese P., Castro M.G., Lowenstein P.R., et al. Platelets mediate cytotoxic T lymphocyte-induced liver damage. Nat Med 11 (2005) 1167-1169
-
(2005)
Nat Med
, vol.11
, pp. 1167-1169
-
-
Iannacone, M.1
Sitia, G.2
Isogawa, M.3
Marchese, P.4
Castro, M.G.5
Lowenstein, P.R.6
-
26
-
-
37349096941
-
Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus
-
Iannacone M., Sitia G., Narvaiza I., Ruggeri Z.M., and Guidotti L.G. Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus. Clin Vaccine Immunol 14 (2007) 1532-1535
-
(2007)
Clin Vaccine Immunol
, vol.14
, pp. 1532-1535
-
-
Iannacone, M.1
Sitia, G.2
Narvaiza, I.3
Ruggeri, Z.M.4
Guidotti, L.G.5
-
27
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
Day C.L., Kaufmann D.E., Kiepiela P., Brown J.A., Moodley E.S., Reddy S., et al. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443 (2006) 350-354
-
(2006)
Nature
, vol.443
, pp. 350-354
-
-
Day, C.L.1
Kaufmann, D.E.2
Kiepiela, P.3
Brown, J.A.4
Moodley, E.S.5
Reddy, S.6
-
28
-
-
39549087674
-
CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation
-
Northfield J.W., Kasprowicz V., Lucas M., Kersting N., Bengsch B., Kim A., et al. CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation. Hepatology 47 (2008) 396-406
-
(2008)
Hepatology
, vol.47
, pp. 396-406
-
-
Northfield, J.W.1
Kasprowicz, V.2
Lucas, M.3
Kersting, N.4
Bengsch, B.5
Kim, A.6
-
29
-
-
33645110247
-
Do antiviral CD8+ T cells select hepatitis C virus escape mutants? Analysis in diverse epitopes targeted by human intrahepatic CD8+ T lymphocytes
-
Komatsu T., Lauer G.M., Pybus O.G., Ouchi K., Wong D., Ward S., et al. Do antiviral CD8+ T cells select hepatitis C virus escape mutants? Analysis in diverse epitopes targeted by human intrahepatic CD8+ T lymphocytes. J Viral Hepat 13 (2006) 121-130
-
(2006)
J Viral Hepat
, vol.13
, pp. 121-130
-
-
Komatsu, T.1
Lauer, G.M.2
Pybus, O.G.3
Ouchi, K.4
Wong, D.5
Ward, S.6
-
30
-
-
34848825909
-
Antiviral activity and hepatoprotection by heme oxygenase-1 in hepatitis B virus infection
-
Protzer U., Seyfried S., Quasdorff M., Sass G., Svorcova M., Webb D., et al. Antiviral activity and hepatoprotection by heme oxygenase-1 in hepatitis B virus infection. Gastroenterology 133 (2007) 1156-1165
-
(2007)
Gastroenterology
, vol.133
, pp. 1156-1165
-
-
Protzer, U.1
Seyfried, S.2
Quasdorff, M.3
Sass, G.4
Svorcova, M.5
Webb, D.6
-
31
-
-
45249096077
-
A concerted action of HNF4alpha and HNF1 alpha links hepatitis B virus replication to hepatocyte differentiation
-
Quasdorff M., Hösel M., Odenthal M., Zedler U., Bohne F., Gripon P., et al. A concerted action of HNF4alpha and HNF1 alpha links hepatitis B virus replication to hepatocyte differentiation. Cell Microbiol 10 (2008) 1478-1490
-
(2008)
Cell Microbiol
, vol.10
, pp. 1478-1490
-
-
Quasdorff, M.1
Hösel, M.2
Odenthal, M.3
Zedler, U.4
Bohne, F.5
Gripon, P.6
-
32
-
-
44949180106
-
Understanding the immunopathogenesis of chronic hepatitis B virus: an Asian prospective
-
Tan A.T., Koh S., Goh V., and Bertoletti A. Understanding the immunopathogenesis of chronic hepatitis B virus: an Asian prospective. J Gastroenterol Hepatol 23 (2008) 833-843
-
(2008)
J Gastroenterol Hepatol
, vol.23
, pp. 833-843
-
-
Tan, A.T.1
Koh, S.2
Goh, V.3
Bertoletti, A.4
-
33
-
-
58849091856
-
-
Icard V., Diaz O., Scholtes C., Perrin-Cocon L., Ramiere C., Bartenschlager R., et al. PLoS One 4 (2009) e4233
-
(2009)
PLoS One
, vol.4
-
-
Icard, V.1
Diaz, O.2
Scholtes, C.3
Perrin-Cocon, L.4
Ramiere, C.5
Bartenschlager, R.6
-
34
-
-
42949130180
-
-
Appel N., Zayas M., Miller S., Krijnse-Locker J., Schaller T., Friebe P., et al. PLoS Pathog 4 (2008) e1000035
-
(2008)
PLoS Pathog
, vol.4
-
-
Appel, N.1
Zayas, M.2
Miller, S.3
Krijnse-Locker, J.4
Schaller, T.5
Friebe, P.6
-
35
-
-
50949132884
-
Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors
-
Paeshuyse J., Vliegen I., Coelmont L., Leyssen P., Tabarrini O., Herdewijn P., et al. Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors. Antimicrob Agents Chemother 52 (2008) 3433-3437
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 3433-3437
-
-
Paeshuyse, J.1
Vliegen, I.2
Coelmont, L.3
Leyssen, P.4
Tabarrini, O.5
Herdewijn, P.6
-
36
-
-
33750691709
-
PD-1 expression in acute hepatitis C virus (HcV) infection is associated with HCV-specific exhaustion
-
Urbani S., Amadei B., Fisicaro P., Tola D., Orlandini A., Sacchelli L., et al. PD-1 expression in acute hepatitis C virus (HcV) infection is associated with HCV-specific exhaustion. J Virol 80 (2006) 11398-11403
-
(2006)
J Virol
, vol.80
, pp. 11398-11403
-
-
Urbani, S.1
Amadei, B.2
Fisicaro, P.3
Tola, D.4
Orlandini, A.5
Sacchelli, L.6
-
37
-
-
19944421720
-
Chronic infection with hepatitis B viruses and antiviral drug evaluation in uPA mice after liver repopulation with tupaia hepatocytes
-
Dandri M., Burda M.R., Zuckerman D.M., Wursthorn K., Matschl U., Pollok J.M., et al. Chronic infection with hepatitis B viruses and antiviral drug evaluation in uPA mice after liver repopulation with tupaia hepatocytes. J Hepatol 42 (2005) 54-60
-
(2005)
J Hepatol
, vol.42
, pp. 54-60
-
-
Dandri, M.1
Burda, M.R.2
Zuckerman, D.M.3
Wursthorn, K.4
Matschl, U.5
Pollok, J.M.6
-
38
-
-
2142698221
-
Transplantation of human hepatocytes in immunodeficient UPA mice: a model for the study of hepatitis B virus
-
Petersen J., Burda M.R., Dandri M., and Rogler C.E. Transplantation of human hepatocytes in immunodeficient UPA mice: a model for the study of hepatitis B virus. Methods Mol Med 96 (2004) 253-260
-
(2004)
Methods Mol Med
, vol.96
, pp. 253-260
-
-
Petersen, J.1
Burda, M.R.2
Dandri, M.3
Rogler, C.E.4
-
39
-
-
40449096921
-
Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein
-
Petersen J., Dandri M., Mier W., Lütgehetmann M., Volz T., von Weizsacker F., et al. Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein. Nat Biotechnol 26 (2008) 335-341
-
(2008)
Nat Biotechnol
, vol.26
, pp. 335-341
-
-
Petersen, J.1
Dandri, M.2
Mier, W.3
Lütgehetmann, M.4
Volz, T.5
von Weizsacker, F.6
-
40
-
-
58249089400
-
The role of negative costimulators during parasitic infections
-
Lepenies B., and Jacobs T. The role of negative costimulators during parasitic infections. Endocr Metab Immune Disord Drug Targets 8 (2008) 279-288
-
(2008)
Endocr Metab Immune Disord Drug Targets
, vol.8
, pp. 279-288
-
-
Lepenies, B.1
Jacobs, T.2
-
41
-
-
34247639547
-
CTLA-4 blockade differentially influences the outcome of non-lethal and lethal Plasmodium yoelii infections
-
Lepenies B., Gaworski I., Tartz S., Langhorne J., Fleischer B., and Jacobs T. CTLA-4 blockade differentially influences the outcome of non-lethal and lethal Plasmodium yoelii infections. Microbes Infect 9 (2007) 687-694
-
(2007)
Microbes Infect
, vol.9
, pp. 687-694
-
-
Lepenies, B.1
Gaworski, I.2
Tartz, S.3
Langhorne, J.4
Fleischer, B.5
Jacobs, T.6
-
42
-
-
0036721695
-
Murine malaria is exacerbated by CTLA-4 blockade
-
Jacobs T., Graefe S.E., Niknafs S., Gaworski I., and Fleischer B. Murine malaria is exacerbated by CTLA-4 blockade. J Immunol 169 (2002) 2323-2329
-
(2002)
J Immunol
, vol.169
, pp. 2323-2329
-
-
Jacobs, T.1
Graefe, S.E.2
Niknafs, S.3
Gaworski, I.4
Fleischer, B.5
-
43
-
-
4744342557
-
Macrophages, pathology and parasite persistence in experimental visceral leishmaniasis
-
Engewerda C.R., Ato M., and Kaye P.M. Macrophages, pathology and parasite persistence in experimental visceral leishmaniasis. Trends Parasitol 20 (2004) 524-530
-
(2004)
Trends Parasitol
, vol.20
, pp. 524-530
-
-
Engewerda, C.R.1
Ato, M.2
Kaye, P.M.3
-
44
-
-
29644444805
-
Sexual dimorphism in the control of amoebic liver abscess in a mouse model of disease
-
Lotter H., Jacobs T., Gaworski I., and Tannich E. Sexual dimorphism in the control of amoebic liver abscess in a mouse model of disease. Infect Immun 74 (2006) 118-124
-
(2006)
Infect Immun
, vol.74
, pp. 118-124
-
-
Lotter, H.1
Jacobs, T.2
Gaworski, I.3
Tannich, E.4
-
45
-
-
36448983633
-
Protective immune mechanisms in helminth infection
-
Anthony R.M., Rutitzky L.I., Urban J.F.J., Stadecker M.J., and Gause W.C. Protective immune mechanisms in helminth infection. Nat Rev Immunol 7 (2007) 975-987
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 975-987
-
-
Anthony, R.M.1
Rutitzky, L.I.2
Urban, J.F.J.3
Stadecker, M.J.4
Gause, W.C.5
-
46
-
-
58849096312
-
Dendritic cell IL-23 and IL-1 production in response to schistosome eggs induces Th17 cells in a mouse strain prone to severe immunopathology
-
Shainheit M.G., Smith P.M., Bazzone L.E., Wang A.C., Rutitzky L.I., and Stadecker M.J. Dendritic cell IL-23 and IL-1 production in response to schistosome eggs induces Th17 cells in a mouse strain prone to severe immunopathology. J Immunol 181 (2008) 8559-8567
-
(2008)
J Immunol
, vol.181
, pp. 8559-8567
-
-
Shainheit, M.G.1
Smith, P.M.2
Bazzone, L.E.3
Wang, A.C.4
Rutitzky, L.I.5
Stadecker, M.J.6
-
47
-
-
41649093318
-
Inflammatory mechanisms in the regulation of insulin resistance
-
Tilg H., and Moschen A.R. Inflammatory mechanisms in the regulation of insulin resistance. Mol Med 14 (2008) 222-231
-
(2008)
Mol Med
, vol.14
, pp. 222-231
-
-
Tilg, H.1
Moschen, A.R.2
-
48
-
-
55649103668
-
Insulin resistance, inflammation, and non-alcoholic fatty liver disease
-
Tilg H., and Moschen A.R. Insulin resistance, inflammation, and non-alcoholic fatty liver disease. Trends Endocrinol Metab 19 (2008) 371-379
-
(2008)
Trends Endocrinol Metab
, vol.19
, pp. 371-379
-
-
Tilg, H.1
Moschen, A.R.2
-
49
-
-
33748992313
-
Adipocytokines: mediators linking adipose tissue, inflammation and immunity
-
Tilg H., and Moschen A.R. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol 6 (2006) 772-783
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 772-783
-
-
Tilg, H.1
Moschen, A.R.2
-
50
-
-
30044431801
-
From fat to inflammation
-
Day C.P. From fat to inflammation. Gastroenterology 130 (2006) 207-210
-
(2006)
Gastroenterology
, vol.130
, pp. 207-210
-
-
Day, C.P.1
-
51
-
-
33847008303
-
Genetics of alcoholic liver disease and nonalcoholic fatty liver disease
-
Wilfred de Alwis N.M., and Day C.P. Genetics of alcoholic liver disease and nonalcoholic fatty liver disease. Semin Liver Dis 27 (2007) 44-54
-
(2007)
Semin Liver Dis
, vol.27
, pp. 44-54
-
-
Wilfred de Alwis, N.M.1
Day, C.P.2
-
52
-
-
59849091830
-
Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis
-
Nowell M.A., Williams A.S., Carty S.A., Scheller J., Hayes A.J., Jones G.W., et al. Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis. J Immunol 182 (2009) 613-622
-
(2009)
J Immunol
, vol.182
, pp. 613-622
-
-
Nowell, M.A.1
Williams, A.S.2
Carty, S.A.3
Scheller, J.4
Hayes, A.J.5
Jones, G.W.6
-
53
-
-
55249092252
-
Structure-guided optimization of the interleukin-6 trans-signaling antagonist sgp130
-
Tenhumberg S., Waetzig G.H., Chalaris A., Rabe B., Seegert D., Scheller J., et al. Structure-guided optimization of the interleukin-6 trans-signaling antagonist sgp130. J Biol Chem 283 (2008) 27200-27207
-
(2008)
J Biol Chem
, vol.283
, pp. 27200-27207
-
-
Tenhumberg, S.1
Waetzig, G.H.2
Chalaris, A.3
Rabe, B.4
Seegert, D.5
Scheller, J.6
-
54
-
-
34248341267
-
The IL-6/sIL-6R complex as a novel target for therapeutic approaches
-
Rose-John S., Waetzig G.H., Scheller J., Grötzinger J., and Seegert D. The IL-6/sIL-6R complex as a novel target for therapeutic approaches. Expert Opin Ther Targets 11 (2007) 613-624
-
(2007)
Expert Opin Ther Targets
, vol.11
, pp. 613-624
-
-
Rose-John, S.1
Waetzig, G.H.2
Scheller, J.3
Grötzinger, J.4
Seegert, D.5
-
55
-
-
44349149913
-
Molecular dissection of gp130-dependent pathways in hepatocytes during liver regeneration
-
Dierssen U., Beraza N., Lutz H.H., Liedtke C., Ernst M., Wasmuth H.E., et al. Molecular dissection of gp130-dependent pathways in hepatocytes during liver regeneration. J Biol Chem 283 (2008) 9886-9895
-
(2008)
J Biol Chem
, vol.283
, pp. 9886-9895
-
-
Dierssen, U.1
Beraza, N.2
Lutz, H.H.3
Liedtke, C.4
Ernst, M.5
Wasmuth, H.E.6
-
56
-
-
20444395122
-
Infections and autoimmunity - good or bad?
-
Christen U., and von Herrath M.G. Infections and autoimmunity - good or bad?. J Immunol 174 (2005) 7481-7486
-
(2005)
J Immunol
, vol.174
, pp. 7481-7486
-
-
Christen, U.1
von Herrath, M.G.2
-
57
-
-
45149109642
-
A novel model for human autoimmune hepatitis: breaking tolerance to human CYP2D6 by viral infection
-
Holdener M., Hintermann H., Rhode A., Wolfe T., Gonzalez F.J., Johnson E.F., et al. A novel model for human autoimmune hepatitis: breaking tolerance to human CYP2D6 by viral infection. J Exp Med 205 (2008) 1409-1422
-
(2008)
J Exp Med
, vol.205
, pp. 1409-1422
-
-
Holdener, M.1
Hintermann, H.2
Rhode, A.3
Wolfe, T.4
Gonzalez, F.J.5
Johnson, E.F.6
-
58
-
-
0036268641
-
Apoptosis of autoreactive CD8 lymphocytes as a potential mechanism for the abrogation of type 1 diabetes by islet-specific TNF-alpha expression at a time when the autoimmune process is already ongoing
-
Christen U., and von Herrath M.G. Apoptosis of autoreactive CD8 lymphocytes as a potential mechanism for the abrogation of type 1 diabetes by islet-specific TNF-alpha expression at a time when the autoimmune process is already ongoing. Ann NY Acad Sci 958 (2002) 166-169
-
(2002)
Ann NY Acad Sci
, vol.958
, pp. 166-169
-
-
Christen, U.1
von Herrath, M.G.2
-
59
-
-
33646052605
-
Functional study of CD4+CD25+ regulatory T cells in health and autoimmune hepatitis
-
Longhi M.S., Hussain M.J., Mitry R.R., Arora S.K., Mieli-Vergani G., Vergani D., et al. Functional study of CD4+CD25+ regulatory T cells in health and autoimmune hepatitis. J Immunol 176 (2006) 4484-4491
-
(2006)
J Immunol
, vol.176
, pp. 4484-4491
-
-
Longhi, M.S.1
Hussain, M.J.2
Mitry, R.R.3
Arora, S.K.4
Mieli-Vergani, G.5
Vergani, D.6
-
60
-
-
22444436491
-
Effect of CD4+ CD25+ regulatory T-cells on CD8 T-cell function in patients with autoimmune hepatitis
-
Longhi M.S., Ma Y., Mitry R.R., Bogdanos D.P., Heneghan M.A., Cheeseman P., et al. Effect of CD4+ CD25+ regulatory T-cells on CD8 T-cell function in patients with autoimmune hepatitis. J Autoimmun 25 (2005) 63-71
-
(2005)
J Autoimmun
, vol.25
, pp. 63-71
-
-
Longhi, M.S.1
Ma, Y.2
Mitry, R.R.3
Bogdanos, D.P.4
Heneghan, M.A.5
Cheeseman, P.6
-
61
-
-
34249895621
-
Cytochrome P450IID6-specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2
-
Longhi M.S., Hussain M.J., Bogdanos D.P., Quaglia A., Mieli-Vergani G., Ma Y., et al. Cytochrome P450IID6-specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2. Hepatology 46 (2007) 472-484
-
(2007)
Hepatology
, vol.46
, pp. 472-484
-
-
Longhi, M.S.1
Hussain, M.J.2
Bogdanos, D.P.3
Quaglia, A.4
Mieli-Vergani, G.5
Ma, Y.6
-
62
-
-
33644852500
-
Polyclonal T-cell responses to cytochrome P450IID6 are associated with disease activity in autoimmune hepatitis type 2
-
Ma Y., Bogdanos D.P., Hussain M.J., Underhill J., Bansal S., Longhi M.S., et al. Polyclonal T-cell responses to cytochrome P450IID6 are associated with disease activity in autoimmune hepatitis type 2. Gastroenterology 130 (2006) 868-882
-
(2006)
Gastroenterology
, vol.130
, pp. 868-882
-
-
Ma, Y.1
Bogdanos, D.P.2
Hussain, M.J.3
Underhill, J.4
Bansal, S.5
Longhi, M.S.6
-
63
-
-
0034728877
-
Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis
-
Wies I., Brunner S., Henninger J., Herkel J., Kanzler S., Meyer zum Buschenfelde K.H., et al. Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis. Lancet 355 (2000) 1510-1515
-
(2000)
Lancet
, vol.355
, pp. 1510-1515
-
-
Wies, I.1
Brunner, S.2
Henninger, J.3
Herkel, J.4
Kanzler, S.5
Meyer zum Buschenfelde, K.H.6
-
64
-
-
0036070963
-
Establishment of standardised SLA/LP immunoassays: specificity for autoimmune hepatitis, worldwide occurrence, and clinical characteristics
-
Baeres M., Herkel J., Czaja A.J., Wies I., Kanzler S., Cancado E.L., et al. Establishment of standardised SLA/LP immunoassays: specificity for autoimmune hepatitis, worldwide occurrence, and clinical characteristics. Gut 51 (2002) 259-264
-
(2002)
Gut
, vol.51
, pp. 259-264
-
-
Baeres, M.1
Herkel, J.2
Czaja, A.J.3
Wies, I.4
Kanzler, S.5
Cancado, E.L.6
-
65
-
-
33845763611
-
RNA-dependent conversion of phosphoserin forms selenocysteine in eukaryotes and archaea
-
Yuan J., Palioura S., Salazar J.C., Su D., O'Donoghue P., Hohn M.J., et al. RNA-dependent conversion of phosphoserin forms selenocysteine in eukaryotes and archaea. Proc Natl Acad Sci USA 103 (2006) 18923-18927
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18923-18927
-
-
Yuan, J.1
Palioura, S.2
Salazar, J.C.3
Su, D.4
O'Donoghue, P.5
Hohn, M.J.6
-
66
-
-
57349163208
-
Identification of CD4 T-cell epitopes in soluble liver antigen/liver pancreas autoantigen in autoimmune hepatitis
-
Mix H., Weiler-Normann C., Thimme R., Ahlenstiel G., Shin E.C., Herkel J., et al. Identification of CD4 T-cell epitopes in soluble liver antigen/liver pancreas autoantigen in autoimmune hepatitis. Gastroenterology 135 (2008) 2107-2118
-
(2008)
Gastroenterology
, vol.135
, pp. 2107-2118
-
-
Mix, H.1
Weiler-Normann, C.2
Thimme, R.3
Ahlenstiel, G.4
Shin, E.C.5
Herkel, J.6
-
68
-
-
10644262224
-
Sidechain biology and the immunogenicity of PDC-E2, the major autoantigen of primary biliary cirrhosis
-
Mao T.K., Davis P.A., Odin J.A., Coppel R.L., and Gershwin M.E. Sidechain biology and the immunogenicity of PDC-E2, the major autoantigen of primary biliary cirrhosis. Hepatology 40 (2004) 1241-1248
-
(2004)
Hepatology
, vol.40
, pp. 1241-1248
-
-
Mao, T.K.1
Davis, P.A.2
Odin, J.A.3
Coppel, R.L.4
Gershwin, M.E.5
-
69
-
-
51749110645
-
Is autoimmunity a matter of sex?
-
Lleo A., Battenzzati P.M., Selmi C., Gershwin M.E., and Podda M. Is autoimmunity a matter of sex?. Autoimmun Rev 7 (2008) 626-630
-
(2008)
Autoimmun Rev
, vol.7
, pp. 626-630
-
-
Lleo, A.1
Battenzzati, P.M.2
Selmi, C.3
Gershwin, M.E.4
Podda, M.5
-
70
-
-
47949101391
-
Role of hepatic phospholipids in development of liver injury in Mdr2 (Abcb4) knockout mice
-
Baghdasaryan A., Fickert P., Fuchsbichler A., Silbert D., Grumhold J., Hörl G., et al. Role of hepatic phospholipids in development of liver injury in Mdr2 (Abcb4) knockout mice. Liver Int 28 (2008) 948-958
-
(2008)
Liver Int
, vol.28
, pp. 948-958
-
-
Baghdasaryan, A.1
Fickert, P.2
Fuchsbichler, A.3
Silbert, D.4
Grumhold, J.5
Hörl, G.6
-
71
-
-
24644525006
-
Overlap syndromes of cholestatic liver diseases and auto-immune hepatitis
-
Schramm C., and Lohse A.W. Overlap syndromes of cholestatic liver diseases and auto-immune hepatitis. Clin Rev Allergy Immunol 28 (2005) 105-114
-
(2005)
Clin Rev Allergy Immunol
, vol.28
, pp. 105-114
-
-
Schramm, C.1
Lohse, A.W.2
-
72
-
-
21344437771
-
Primary sclerosing cholangitis is a premalignant condition
-
Schramm C., and Galle P.R. Primary sclerosing cholangitis is a premalignant condition. Z Gastroenterol 43 (2005) 607-611
-
(2005)
Z Gastroenterol
, vol.43
, pp. 607-611
-
-
Schramm, C.1
Galle, P.R.2
-
73
-
-
50049125047
-
Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses
-
Ermolaeva M.A., Michallet M.C., Papadopoulou N., Utermöhlen O., Kranidioti K., Kollias G., et al. Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses. Nat Immunol 9 (2008) 1037-1046
-
(2008)
Nat Immunol
, vol.9
, pp. 1037-1046
-
-
Ermolaeva, M.A.1
Michallet, M.C.2
Papadopoulou, N.3
Utermöhlen, O.4
Kranidioti, K.5
Kollias, G.6
-
74
-
-
53249111250
-
P38 alpha MAPK inhibits JNK activation and collaborates with IkappaB kinase 2 to prevent endotoxin-induced liver failure
-
Heinrichsdorff J., Luedde T., Perdiguero E., Nebreda A.R., and Pasparakis M. P38 alpha MAPK inhibits JNK activation and collaborates with IkappaB kinase 2 to prevent endotoxin-induced liver failure. EMBO Rep 9 (2008) 1048-1054
-
(2008)
EMBO Rep
, vol.9
, pp. 1048-1054
-
-
Heinrichsdorff, J.1
Luedde, T.2
Perdiguero, E.3
Nebreda, A.R.4
Pasparakis, M.5
-
75
-
-
33846839443
-
Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma
-
Luedde T., Beraza N., Kotsikoris V., van Loo G., Nenci A., De Vos R., et al. Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell 11 (2007) 119-132
-
(2007)
Cancer Cell
, vol.11
, pp. 119-132
-
-
Luedde, T.1
Beraza, N.2
Kotsikoris, V.3
van Loo, G.4
Nenci, A.5
De Vos, R.6
-
76
-
-
36248962566
-
Molecular mechanisms of liver carcinogenesis in the mdr2-knockout mice
-
Katzenellenbogen M., Mizrahi L., Pappo O., Klopstock N., Olam D., Jacob-Hirsch J., et al. Molecular mechanisms of liver carcinogenesis in the mdr2-knockout mice. Mol Cancer Res 5 (2007) 1159-1170
-
(2007)
Mol Cancer Res
, vol.5
, pp. 1159-1170
-
-
Katzenellenbogen, M.1
Mizrahi, L.2
Pappo, O.3
Klopstock, N.4
Olam, D.5
Jacob-Hirsch, J.6
-
77
-
-
33646247610
-
Multiple adaptive mechanisms to chronic liver disease revealed at early stages of liver carcinogenesis in the Mdr2-knockout mice
-
Katzenellenbogen B.S., Pappo O., Barash H., Klopstock N., Mizrahi L., Olam D., et al. Multiple adaptive mechanisms to chronic liver disease revealed at early stages of liver carcinogenesis in the Mdr2-knockout mice. Cancer Res 66 (2006) 4001-4010
-
(2006)
Cancer Res
, vol.66
, pp. 4001-4010
-
-
Katzenellenbogen, B.S.1
Pappo, O.2
Barash, H.3
Klopstock, N.4
Mizrahi, L.5
Olam, D.6
|