-
1
-
-
37349000365
-
The role of pneumolysin in mediating lung damage in a lethal pneumococcal pneumonia murine model
-
del Mar García-Suárez M, Flórez N, Astudillo A, et al. The role of pneumolysin in mediating lung damage in a lethal pneumococcal pneumonia murine model. Respir Res 2007; 8: 3.
-
(2007)
Respir Res
, vol.8
, pp. 3
-
-
Del Mar García-Suárez, M.1
Flórez, N.2
Astudillo, A.3
-
2
-
-
53149104367
-
Pneumolysin: A double-edged sword during the host-pathogen interaction
-
Marriott HM, Mitchell TJ, Dockrell DH. Pneumolysin: a double-edged sword during the host-pathogen interaction. Curr Mol Med 2008; 8: 497-509.
-
(2008)
Curr Mol Med
, vol.8
, pp. 497-509
-
-
Marriott, H.M.1
Mitchell, T.J.2
Dockrell, D.H.3
-
3
-
-
0037452778
-
Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection
-
DOI 10.1073/pnas.0435928100
-
Malley R, Henneke P, Morse SC, et al. Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection. Proc Natl Acad Sci USA 2003; 100: 1966-1971. (Pubitemid 36254557)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.4
, pp. 1966-1971
-
-
Malley, R.1
Henneke, P.2
Morse, S.C.3
Cieslewicz, M.J.4
Lipsitch, M.5
Thompson, C.M.6
Kurt-Jones, E.7
Paton, J.C.8
Wessels, M.R.9
Golenbock, D.T.10
-
4
-
-
0035865826
-
Proinflammatory interactions of pneumolysin with human neutrophils
-
DOI 10.1086/318536
-
Cockeran R, Theron AJ, Steel HC, et al. Proinflammatory interactions of pneumolysin with human neutrophils. J Infect Dis 2001; 183: 604-611. (Pubitemid 32147516)
-
(2001)
Journal of Infectious Diseases
, vol.183
, Issue.4
, pp. 604-611
-
-
Cockeran, R.1
Theron, A.J.2
Steel, H.C.3
Matlola, N.M.4
Mitchell, T.J.5
Feldman, C.6
Anderson, R.7
-
5
-
-
33744959839
-
Epithelial cells are sensitive detectors of bacterial pore-forming toxins
-
DOI 10.1074/jbc.M511431200
-
Ratner AJ, Hippe KR, Aguilar JL, et al. Epithelial cells are sensitive detectors of bacterial pore-forming toxins. J Biol Chem 2006; 281: 12994-12998. (Pubitemid 43855393)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.18
, pp. 12994-12998
-
-
Ratner, A.J.1
Hippe, K.R.2
Aguilar, J.L.3
Bender, M.H.4
Nelson, A.L.5
Weiser, J.N.6
-
6
-
-
0037103529
-
Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro
-
DOI 10.1086/341563
-
Cockeran R, Durandt C, Feldman C, et al. Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vivo. J Infect Dis 2002; 186: 562-565. (Pubitemid 34876268)
-
(2002)
Journal of Infectious Diseases
, vol.186
, Issue.4
, pp. 562-565
-
-
Cockeran, R.1
Durandt, C.2
Feldman, C.3
Mitchell, T.J.4
Anderson, R.5
-
7
-
-
0036139243
-
Induction of gamma interferon and nitric oxide by truncated pneumolysin that lacks pore-forming activity
-
DOI 10.1128/IAI.70.1.107-113.2002
-
Baba H, Kawamura I, Kohda C, et al. Induction of gamma interferon and nitric oxide by truncated pneumolysin that lacks pore-forming activity. Infect Immun 2002; 70: 107-113. (Pubitemid 34028605)
-
(2002)
Infection and Immunity
, vol.70
, Issue.1
, pp. 107-113
-
-
Baba, H.1
Kawamura, I.2
Kohda, C.3
Nomura, T.4
Ito, Y.5
Kimoto, T.6
Watanabe, I.7
Ichiyama, S.8
Mitsuyama, M.9
-
8
-
-
45549108765
-
Tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signalling
-
Koga T, Lim JH, Jono H, et al. Tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signalling. J Biol Chem 2008; 283: 12546-12554.
-
(2008)
J Biol Chem
, vol.283
, pp. 12546-12554
-
-
Koga, T.1
Lim, J.H.2
Jono, H.3
-
9
-
-
0033984374
-
Matrix metalloproteinases contribute to brain damage in experimental pneumococcal meningitis
-
DOI 10.1128/IAI.68.2.615-620.2000
-
Leib SL, Leppert D, Clements J, et al. Matrix metalloproteinases contribute to brain damage in experimental pneumococcal meningitis. Infect Immun 2000; 68: 615-620. (Pubitemid 30056514)
-
(2000)
Infection and Immunity
, vol.68
, Issue.2
, pp. 615-620
-
-
Leib, S.L.1
Leppert, D.2
Clements, J.3
Tauber, M.G.4
-
10
-
-
0034455606
-
Matrix metalloproteinase (MMP)-8 and MMP-9 in cerebrospinal fluid during bacterial meningitis: Association with blood-brain barrier damage and neurological sequelae
-
DOI 10.1086/313922
-
Leppert D, Leib SL, Grygar C, et al. Matrix metalloproteinase (MMP)-8 and MMP-9 in cerebrospinal fluid during bacterial meningitis: association with blood-brain barrier damage and neurological sequelae. Clin Infect Dis 2000; 31: 80-84. (Pubitemid 32268943)
-
(2000)
Clinical Infectious Diseases
, vol.31
, Issue.1
, pp. 80-84
-
-
Leppert, D.1
Leib, S.L.2
Grygar, C.3
Miller, K.M.4
Schaad, U.B.5
Hollander, G.A.6
-
11
-
-
0037441783
-
Pulmonary matrix metalloproteinase excess in hospital-acquired pneumonia
-
Hartog CM, Wermelt JA, Sommerfeld GO, et al. Pulmonary matrix metalloproteinase excess in hospital-acquired pneumonia. Am J Respir Crit Care Med 2003; 167: 593-598.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 593-598
-
-
Hartog, C.M.1
Wermelt, J.A.2
Sommerfeld, G.O.3
-
12
-
-
0037738484
-
Matrix metalloproteinase-9 in pneumococcal meningitis: Activation via an oxidative pathway
-
DOI 10.1086/374644
-
Meli DN, Christen S, Leib SL. Matrix metalloproteinase-9 in pneumococcal meningitis: activation via an oxidative pathway. J Infect Dis 2003; 187: 1411-1415. (Pubitemid 36549686)
-
(2003)
Journal of Infectious Diseases
, vol.187
, Issue.9
, pp. 1411-1415
-
-
Meli, D.N.1
Christen, S.2
Leib, S.L.3
-
13
-
-
33749334618
-
Inhibition of matrix metalloproteinase-9 prevents neutrophilic inflammation in ventilator-induced lung injury
-
Kim JH, Suk MH, Yoon DW, et al. Inhibition of matrix metalloproteinase-9 prevents neutrophilic inflammation in ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol 2006; 291: L580-L587.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
-
-
Kim, J.H.1
Suk, M.H.2
Yoon, D.W.3
-
14
-
-
34447301502
-
Polymorphonuclear leukocytes promote neurotoxicity through release of matrix metalloproteinases, reactive oxygen species, and TNF-α
-
Nguyen X, O'Barr TJ, Anderson AJ. Polymorphonuclear leukocytes promote neurotoxicity through release of matrix metalloproteinases, reactive oxygen species, and TNF-α. J Neurochem 2007; 102: 900-912.
-
(2007)
J Neurochem
, vol.102
, pp. 900-912
-
-
Nguyen, X.1
O'Barr, T.J.2
Anderson, A.J.3
-
15
-
-
50249161572
-
Hospital acquired pneumonia with high-risk bacteria is associated with increased pulmonary matrix metalloproteinase activity
-
Schaaf B, Liebau C, Kurowski V, et al. Hospital acquired pneumonia with high-risk bacteria is associated with increased pulmonary matrix metalloproteinase activity. BMC Pulm Med 2008; 8: 12.
-
(2008)
BMC Pulm Med
, vol.8
, pp. 12
-
-
Schaaf, B.1
Liebau, C.2
Kurowski, V.3
-
16
-
-
0024407229
-
Pneumolysin, the thiol-activated toxin of Streptococcus pneumoniae, does not require a thiol group for in vitro activity
-
Saunders FK, Mitchell TJ, Walker JA, et al. Pneumolysin, the thiol-activated toxin of Streptococcus pneumoniae, does not require a thiol group for in vitro activity. Infect Immun 1989; 57: 2547-2552. (Pubitemid 19183872)
-
(1989)
Infection and Immunity
, vol.57
, Issue.8
, pp. 2547-2552
-
-
Saunders, F.K.1
Mitchell, T.J.2
Walker, J.A.3
Andrew, P.W.4
Boulnois, G.J.5
-
17
-
-
9844231490
-
Calcium efflux and influx in f-met-leu-phe (fMLP)-activated human neutrophils are chronologically distinct events
-
Anderson R, Goolam Mahomed A. Calcium efflux and influx in f-met- leu-phe (fMLP)-activated human neutrophils are chronologically distinct events. Clin Exp Immunol 1997; 110: 132-138. (Pubitemid 27428526)
-
(1997)
Clinical and Experimental Immunology
, vol.110
, Issue.1
, pp. 132-138
-
-
Anderson, R.1
Mahomed, A.G.2
-
18
-
-
0021895138
-
2+ indicators with greatly improved fluorescence properties
-
2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985; 260: 3440-3450.
-
(1985)
J Biol Chem
, vol.260
, pp. 3440-3450
-
-
Grynkiewicz, G.1
Poenie, M.2
Tsien, R.Y.3
-
19
-
-
45849151057
-
Neutrophil elastase is needed for neutrophil emigration into lungs in ventilator-induced lung injury
-
DOI 10.1165/rcmb.2007-0315OC
-
Kaynar AM, Houghton AM, Lum EH, et al. Neutrophil elastase is needed for neutrophil emigration into lungs in ventilator-induced lung injury. Am J Respir Cell Mol Biol 2008; 39: 53-60. (Pubitemid 351883958)
-
(2008)
American Journal of Respiratory Cell and Molecular Biology
, vol.39
, Issue.1
, pp. 53-60
-
-
Kaynar, A.M.1
Houghton, A.M.2
Lum, E.H.3
Pitt, B.R.4
Shapiro, S.D.5
-
20
-
-
58149306382
-
Neutrophil elastase mediates innate host protection against Pseudomonas aeruginosa
-
Hirche TO, Benabid R, Deslee G, et al. Neutrophil elastase mediates innate host protection against Pseudomonas aeruginosa. J Immunol 2008; 181: 4945-4954.
-
(2008)
J Immunol
, vol.181
, pp. 4945-4954
-
-
Hirche, T.O.1
Benabid, R.2
Deslee, G.3
-
21
-
-
0033942044
-
In vivo neutrophil recruitment by granulocyte chemotactic protein-2 is assisted by gelatinase B/MMP-9 in the mouse
-
D'Haese A, Wuyts A, Dillen C, et al. In vivo neutrophil recruitment by granulocyte chemotactic protein-2 is assisted by gelatinase B/MMP-9 in the mouse. J Interferon Cytokine Res 2000; 20: 667-674.
-
(2000)
J Interferon Cytokine Res
, vol.20
, pp. 667-674
-
-
D'Haese, A.1
Wuyts, A.2
Dillen, C.3
-
22
-
-
33644840799
-
Matrix metalloproteinase-9 deficiency impairs host defense against abdominal sepsis
-
Renckens R, Roelofs JJ, Florquin S, et al. Matrix metalloproteinase-9 deficiency impairs host defence against abdominal sepsis. J Immunol 2006; 176: 3735-3741. (Pubitemid 43364020)
-
(2006)
Journal of Immunology
, vol.176
, Issue.6
, pp. 3735-3741
-
-
Renckens, R.1
Roelofs, J.J.T.H.2
Florquin, S.3
De Vos, A.F.4
Lijnen, H.R.5
Van'T Veer, C.6
Van Der Poll, T.7
-
23
-
-
0025613913
-
The effect of Streptococcus pneumoniae pneumolysin on human respiratory epithelium in vitro
-
Feldman C, Mitchell TJ, Andrew PW, et al. The effect of Streptococcus pneumoniae pneumolysin on human respiratory epithelium in vitro. Microb Pathog 1990; 9: 275-284.
-
(1990)
Microb Pathog
, vol.9
, pp. 275-284
-
-
Feldman, C.1
Mitchell, T.J.2
Andrew, P.W.3
-
24
-
-
0041767440
-
Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone
-
DOI 10.1128/AAC.47.8.2649-2654.2003
-
Spreer A, Kerstan H, Böttcher T, et al. Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone. Antimicrob Agents Chemother 2003; 47: 2649-2654. (Pubitemid 36919474)
-
(2003)
Antimicrobial Agents and Chemotherapy
, vol.47
, Issue.8
, pp. 2649-2654
-
-
Spreer, A.1
Kerstan, H.2
Bottcher, T.3
Gerber, J.4
Siemer, A.5
Zysk, G.6
Mitchell, T.J.7
Eiffert, H.8
Nau, R.9
-
25
-
-
0033557172
-
Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor
-
DOI 10.1084/jem.189.4.657
-
Gao J-L, Lee EJ, Murphy PM. Impaired antibacterial host defence in mice lacking the N-formylpeptide receptor. J Exp Med 1999; 189: 657-662. (Pubitemid 29193366)
-
(1999)
Journal of Experimental Medicine
, vol.189
, Issue.4
, pp. 657-662
-
-
Gao, J.-L.1
Lee, E.J.2
Murphy, P.M.3
-
26
-
-
0035173647
-
Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo
-
DOI 10.1038/nm1101-1209
-
Partida-Sanchez S, Cockayne DA, Monard S, et al. Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo. Nat Med 2001; 7: 1209-1216. (Pubitemid 33063776)
-
(2001)
Nature Medicine
, vol.7
, Issue.11
, pp. 1209-1216
-
-
Partida-Sanchez, S.1
Cockayne, D.A.2
Monard, S.3
Jacobson, E.L.4
Oppenheimer, N.5
Garvy, B.6
Kusser, K.7
Goodrich, S.8
Howard, M.9
Harmsen, A.10
Randall, T.D.11
Lund, F.E.12
-
27
-
-
0027136744
-
Human neutrophil granules and secretory vesicles
-
Borregaard N, Lollike K, Kjeldsen L, et al. Human neutrophil granules and secretory vesicles. Eur J Haematol 1993; 51: 187-198. (Pubitemid 24014145)
-
(1993)
European Journal of Haematology
, vol.51
, Issue.4
, pp. 187-198
-
-
Borregaard, N.1
Lollike, K.2
Kjeldsen, L.3
Sengelov, H.4
Bastholm, L.5
Nielsen, M.H.6
Bainton, D.F.7
-
28
-
-
0022502259
-
Quantitative analysis of the cytosolic free calcium dependency of exocytosis from three subcellular compartments in intact human neutrophils
-
Lew PD, Monod A, Waldvogel FA, et al. Quantitative analysis of the cytosolic free calcium dependency of exocytosis from three subcellular compartments in intact human neutrophils. J Cell Biol 1986; 102: 2197-2204. (Pubitemid 16052159)
-
(1986)
Journal of Cell Biology
, vol.102
, Issue.6
, pp. 2197-2204
-
-
Lew, P.D.1
Monod, A.2
Waldvogel, F.A.3
-
29
-
-
45549091995
-
Munc13-4 regulates granule secretion in human neutrophils
-
Pivot-Pajot C, Varoqueaux F, de Saint Basile G, et al. Munc13-4 regulates granule secretion in human neutrophils. J Immunol 2008; 180: 6786-6797.
-
(2008)
J Immunol
, vol.180
, pp. 6786-6797
-
-
Pivot-Pajot, C.1
Varoqueaux, F.2
De Saint Basile, G.3
-
30
-
-
33845480503
-
Effects of macrolides on pneumolysin of macrolide-resistant Streptococcus pneumoniae
-
DOI 10.1183/09031936.06.00116805
-
Fukuda Y, Yanagihara K, Higashiyama Y, et al. Effects of macrolides against pneumolysin of macrolide-resistant Streptococcus pneumoniae. Eur Respir J 2006; 27: 1020-1025. (Pubitemid 44911118)
-
(2006)
European Respiratory Journal
, vol.27
, Issue.5
, pp. 1020-1025
-
-
Fukuda, Y.1
Yanagihara, K.2
Higashiyama, Y.3
Miyazaki, Y.4
Hirakata, Y.5
Mukae, H.6
Tomono, K.7
Mizuta, Y.8
Tsukamoto, K.9
Kohno, S.10
-
31
-
-
35448968988
-
Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro
-
DOI 10.1093/jac/dkm338
-
Anderson R, Steel HC, Cockeran R, et al. Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro. J Antimicrob Chemother 2007; 60: 1155-1158. (Pubitemid 47617770)
-
(2007)
Journal of Antimicrobial Chemotherapy
, vol.60
, Issue.5
, pp. 1155-1158
-
-
Anderson, R.1
Steel, H.C.2
Cockeran, R.3
Von Gottberg, A.4
De Gouveia, L.5
Klugman, K.P.6
Mitchell, T.J.7
Feldman, C.8
|