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Volumn 108, Issue SUPPL. 5, 2000, Pages 919-924

Simulation modeling of the tissue disposition of formaldehyde to predict nasal DNA-protein cross-links in Fischer 344 rats, rhesus monkeys, and humans

(3) Conolly, Rory B a Lilly, Patrick D a,b Kimbell, Julia S a

a CIIT CENTERS FOR HEALTH RESEARCH (United States)

b BOEHRINGER INGELHEIM PHARMACEUTICALS INC (United States)

Author keywords

DNA protein crosslinks; Dosimetry; DPX; F344 rat; Formaldehyde; Human; Rhesus monkey; Risk assessment

Indexed keywords

DNA; DNA BINDING PROTEIN; FORMALDEHYDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER RISK; CHEMICAL CARCINOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA CROSS LINKING; DYNAMICS; EXPERIMENTAL ANIMAL; FLUID FLOW; HUMAN; MALE; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; NONHUMAN; NOSE MUCOSA; PREDICTION; PRIORITY JOURNAL; PROTEIN DNA BINDING; RAT; RESPIRATORY TRACT MUCOSA; RHESUS MONKEY; RISK ASSESSMENT; SIMULATION; TISSUE DISTRIBUTION; TOXICITY TESTING;

EID: 0033670964 PISSN: 00916765 EISSN: None Source Type: Journal
DOI: 10.2307/3454325 Document Type: Article

Times cited : (54)

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