ATP, P2 receptors and the renal microcirculation

Purinergic Signalling

Volumn 5, Issue 4, 2009, Pages 447-460

  Inscho, Edward W ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Adenosine; Afferent arteriole; Autoregulation; Hypertension; P2X receptors; Tubuloglomerular feedback

Indexed keywords

EID: 70949089677     PISSN: 15739538     EISSN: 15739546     Source Type: Journal    
DOI: 10.1007/s11302-009-9147-1     Document Type: Review

References (171)

1. MA Bailey KA Hillman RJ Unwin 2000 P2 receptors in the kidney J Auton Nerv Syst 81 264 270 10869730
2. MA Bailey M Imbert-Teboul C Turner S Marsy K Srai G Burnstock RJ Unwin 2000 Axial distribution and characterization of basolateral P2Y receptors along the rat renal tubule Kidney Int 58 1893 1901 11044209
3. MA Bailey CM Turner A Hus-Citharel J Marchetti M Imbert-Teboul P Milner G Burnstock R Unwin 2004 P2Y receptors present in the native and isolated rat glomerulus Nephron Physiol 96 79 90
4. 1 purinoceptors by autoradiography and immunohistochemistry in the rat kidney Am J Physiol Renal Physiol 274 F799 F804
5. CM Chan RJ Unwin G Burnstock 1998 Potential functional roles of extracellular ATP in kidney and urinary tract Exp Nephrol 6 200 207 9639035
6. CM Turner O Vonend C Chan G Burnstock RJ Unwin 2003 The pattern of distribution of selected ATP-sensitive P2 receptor subtypes in normal rat kidney: an immunohistological study Cells Tissues Organs 175 105 117 14605489
7. RJ Unwin MA Bailey G Burnstock 2003 Purinergic signaling along the renal tubule: the current state of play News Physiol Sci 18 237 241 14614156
8. Z Guan DA Osmond EW Inscho 2007 Purinoceptors in the kidney Exp Biol Med 232 715 726
9. i in cultured mouse mesangial cells Am J Physiol Renal Physiol 292 F1380 F1389 17213463
10. J Leipziger 2003 Control of epithelial transport via luminal P2 receptors Am J Physiol Renal Physiol 284 F419 F432 12556361
11. 2+ signaling attenuates P2X receptor-mediated vasoconstriction of afferent arterioles in angiotensin II hypertension Hypertension 46 562 568 16116048
12. EW Inscho 2001 P2 receptors in the regulation of renal microvascular function Am J Physiol Renal Physiol 280 F927 F944 11352833
13. EM Schwiebert BK Kishore 2001 Extracellular nucleotide signaling along the renal epithelium Am J Physiol Renal Physiol 280 F945 F963 11352834
14. EM Schwiebert 2001 ATP release mechanisms, ATP receptors and purinergic signalling along the nephron Clin Exp Pharmacol Physiol 28 340 350 11339211
15. EM Schwiebert A Zsembery 2003 Extracellular ATP as a signaling molecule for epithelial cells Biochim Biophys Acta 1615 7 32 12948585
16. 2Y receptors stimulate renin secretion by rat renal cortical slices J Pharmacol Exp Ther 266 160 163 8331555
17. 2+ signaling and renin secretion in rat juxtaglomerular cells Circ Res 93 338 345 12869388
18. PC Churchill MC Churchill 1988 Effects of adenosine on renin secretion. Atlas of science Pharmacology 2 367 373
19. PC Churchill MC Churchill 1985 A1 and A2 adenosine receptor stimulation inhibits and stimulates renin secretion of rat cortical slices J Pharmacol Exp Ther 232 589 594 2983063
20. J Schnermann 1998 Juxtaglomerular cell complex in the regulation of renal salt excretion Am J Physiol Regul Integr Comp Physiol 274 R263 R279
21. EW Inscho K Ohishi LG Navar 1992 Effects of ATP on pre- and postglomerular juxtamedullary microvasculature Am J Physiol Renal, Fluid Electrolyte Physiol 263 F886 F893
22. H Harada CM Chan A Loesch R Unwin G Burnstock 2000 Induction of proliferation and apoptotic cell death via P2Y and P2X receptors, respectively, in rat glomerular mesangial cells Kidney Int 57 949 958 10720948
23. MG Mohaupt T Fischer J Schwöbel RB Sterzel E Schulze-Lohoff 1998 Activation of purinergic P2Y2 receptors inhibits inducible NO synthase in cultured rat mesangial cells Am J Physiol Renal Physiol 275 F103 F110
24. PK Carmines EW Inscho 1994 Renal arteriolar angiotensin responses during varied adenosine receptor activation Hypertension 23 I114 I119 8282342
25. AN Drury A Szent-Györgyi 1929 The physiological activity of adenine compounds with special reference to their action upon the mammalian heart J Physiol (Lond) 68 213 237
26. PB Hansen H Castrop J Briggs J Schnermann 2003 Adenosine induces vasoconstriction through Gi-dependent activation of phospholipase C in isolated perfused afferent arterioles of mice J Am Soc Nephrol 14 2457 2465 14514723
27. PB Hansen S Hashimoto M Oppermann Y Huang J Briggs J Schnermann 2005 Vasoconstrictor and vasodilator effects of adenosine in the mouse kidney due to preferential activation of A1 or A2 adenosine receptors J Pharmacol Exp Ther 315 1150 1157 16120812
28. PB Hansen J Schnermann 2003 Vasoconstrictor and vasodilator effects of adenosine in the kidney Am J Physiol Renal Physiol 285 F590 F599 12954591
29. FG Holz M Steinhausen 1987 Renovascular effects of adenosine receptor agonists Ren Physiol 10 272 282 3454474
30. AM Ibarrola EW Inscho RC Vari LG Navar 1991 Influence of adenosine receptor blockade on renal function and autoregulation J Am Soc Nephrol 2 991 999 1760542
31. 2 purinergic stimulation Hypertension 17 1033 1037 2045147
32. EW Inscho KD Mitchell LG Navar 1994 Extracellular ATP in the regulation of renal microvascular function FASEB J 8 319 328 8143938
33. 1 receptors in renal microvascular autoregulatory behavior J Clin Invest 112 1895 1905 14679185
34. M Kawabata T Ogawa T Takabatake 1998 Control of rat glomerular microcirculation by juxtaglomerular adenosine A1 receptors Kidney Int 54 S228 S230
35. 2a receptors on renal microvascular reactivity Am J Physiol Renal Physiol 280 F406 F414 11181402
36. A Nishiyama M Rahman EW Inscho 2004 Role of interstitial ATP and adenosine in the regulation of renal hemodynamics and microvascular function Hypertension Research 27 791 804 15824461
37. H Osswald WS Spielman FG Knox 1978 Mechanism of adenosine-mediated decreases in glomerular filtration rate in dogs Circ Res 43 465 469 679428
38. J Schnermann T Traynor TX Yang L Arend YNG Huang A Smart JP Briggs 1998 Tubuloglomerular feedback: new concepts and developments Kidney Int 54 S40 S45
39. GA Eppel SC Malpas KM Denton RG Evans 2004 Neural control of renal medullary perfusion Clin Exp Pharmacol Physiol 31 387 396 15191418
40. 1A receptor-deficient mice Am J Physiol Renal Physiol 275 F922 F927
41. H Weihprecht JN Lorenz JP Briggs J Schnermann 1992 Vasomotor effects of purinergic agonists in isolated rabbit afferent arterioles Am J Physiol Renal Fluid Electrolyte Physiol 263 F1026 F1033
42. H Weihprecht JN Lorenz JP Briggs J Schnermann 1994 Synergistic effects of angiotensin and adenosine in the renal microvasculature Am J Physiol 266 F227 F239 8141324
43. DSA Majid EW Inscho LG Navar 1999 P2 purinoceptor saturation by adenosine triphosphate impairs renal autoregulation in dogs J Am Soc Nephrol 10 492 498 10073599
44. DSA Majid LG Navar 1992 Suppression of blood flow autoregulation plateau during nitric oxide blockade in canine kidney Am J Physiol Renal Fluid Electrolyte Physiol 262 F40 F46
45. 2 purinoceptors in the rat isolated perfused kidney Pflügers Arch 306 139 152
46. 2-purinoceptor activation in spontaneously hypertensive rats Pharmacol 60 47 50
47. F Vargas MRR Moreno A Osuna 1996 Renal vascular reactivity to ATP in ageing rats Med Sci Res 24 263 265
48. F Vargas A Osuna A Fernández-Rivas 1996 Renal vascular reactivity to ATP in hyper- and hypothyroid rats Experientia 52 225 229 8631390 (Pubitemid 26096888)
49. 2 purinergic receptors J Pharmacol Exp Ther 265 334 338 8474016
50. L Dobrowolski A Walkowska E Kompanowska-Jezierska M Kuczeriszka J Sadowski 2007 Effects of ATP on rat renal haemodynamics and excretion: role of sodium intake, nitric oxide and cytochrome P450 Acta Physiologica 189 77 85 17280559
51. 2-purinoceptor activation Am J Physiol Renal, Fluid Electrolyte Physiol 271 F1077 F1085
52. AM Gutierrez M Kornfeld AE Persson 1999 Calcium response to adenosine and ATP in rabbit afferent arterioles Acta Physiol Scand 166 175 181 10468653
53. EW Inscho 2001 Renal microvascular effects of P2 receptor stimulation Clin Exp Pharmacol Physiol 28 332 339 11339210
54. KD Mitchell LG Navar 1993 Modulation of tubuloglomerular feedback responsiveness by extracellular ATP Am J Physiol Renal Fluid Electrolyte Physiol 264 F458 F466
55. LG Navar EW Inscho DSA Majid JD Imig LM Harrison-Bernard KD Mitchell 1996 Paracrine regulation of the renal microcirculation Physiol Rev 76 425 536 8618962
56. GA Eppel S Ventura KM Denton RG Evans 2006 Lack of contribution of P2X receptors to neurally mediated vasoconstriction in the rabbit kidney in vivo Acta Physiologica 186 197 207 16497199
57. GA Eppel S Ventura RG Evans 2007 Regional vascular responses to ATP and ATP analogues in the rabbit kidney in vivo: roles for adenosine receptors and prostanoids Br J Pharmacol 149 523 531
58. PK Carmines EW Inscho RC Gensure 1990 Arterial pressure effects on preglomerular microvasculature of juxtamedullary nephrons Am J Physiol 258 F94 F102 2301599
59. EW Inscho EA LeBlanc BT Pham SM White JD Imig 1999 Purinoceptor-mediated calcium signaling in preglomerular smooth muscle cells Hypertension 33 195 200 9931104
60. EW Inscho AK Cook V Mui J Miller 1998 Direct assessment of renal microvascular responses to P2-purinoceptor agonists Am J Physiol Renal Physiol 274 F718 F727
61. R Wangensteen O Fernandez J Sainz A Quesada F Vargas A Osuna 2000 Contribution of endothelium-derived relaxing factors to P2Y-purinoceptor-induced vasodilation in the isolated rat kidney General Pharmacology: The Vascular System 35 129 133 (Pubitemid 34017497)
62. KD Keef JS Pasco DM Eckman 1992 Purinrgic relaxation and hyperpolarization in guinea pig and rabbit coronary artery: Role of endothelium J Pharmacol Exp Ther 260 592 600 1738109
63. M Malmsjö L Edvinsson D Erlinge 1998 P2U-receptor mediated endothelium-dependent but nitric oxide- independent vascular relaxation Br J Pharmacol 123 719 729 9517392
64. M Malmsjö D Erlinge ED Högestätt PM Zygmunt 1999 Endothelial P2Y receptors induce hyperpolarisation of vascular smooth muscle by release of endothelium-derived hyperpolarising factor Eur J Pharmacol 364 169 173 9932720
65. M Malmsjö Chu ZM K Croft D Erlinge L Edvinsson LJ Beilin 2002 P2Y receptor-induced EDHF vasodilatation is of primary importance for the regulation of perfusion pressure in the peripheral circulation of the rat Acta Physiol Scand 174 301 309 11942917
66. AK Wihlborg M Malmsjö A Eyjolfsson R Gustafsson K Jacobson D Erlinge 2003 Extracellular nucleotides induce vasodilatation in human arteries via prostaglandins, nitric oxide and endothelium-derived hyperpolarising factor Br J Pharmacol 138 1451 1458 12721100
67. J Pfeilschifter 1990 Comparison of extracellular ATP and UTP signalling in rat renal mesangial cells Biochem J 272 469 472 2176464
68. 2+ response of rat mesangial cells to ATP analogues Eur J Pharmacol 369 107 112 10204688
69. M Takeda T Kawamura M Kobayashi H Endou 1996 ATP-induced calcium mobilization in glomerular mesangial cells is mediated by P2u purinoceptor Biochem Mol Biol Int 39 1193 1200 8876973
70. H Pavenstädt J Gloy J Leipziger B Klär J Pfeilschifter P Schollmeyer R Greger 1993 Effect of extracellular ATP on contraction, cytosolic calcium activity, membrane voltage, and ion currents of rat mesangial cells in primary culture Br J Pharmacol 109 953 959 7691366
71. J Pfeilschifter A Huwiler VA Briner 1995 Proliferative mechanisms in kidney cells Curr Opin Nephrol Hypertension 4 98 103
72. EW Inscho TP Belott MJ Mason JB Smith LG Navar 1996 Extracellular ATP increases cytosolic calcium in cultured renal arterial smooth muscle cells Clin Exp Pharmacol Physiol 23 503 507 8800574
73. 2+ signaling in preglomerular smooth muscle cells Am J Physiol Renal Physiol 276 F450 F456
74. SM White JD Imig EW Inscho 2001 Calcium signaling pathways utilized by P2X receptors in preglomerular vascular smooth muscle cells Am J Physiol Renal Physiol 280 F1054 F1061 11352845
75. EW Inscho AK Cook 2002 P2 receptor-mediated afferent arteriolar vasoconstriction during calcium channel blockade Am J Physiol Renal Physiol 282 F245 F255 11788438
76. EW Inscho K Ohishi AK Cook TP Belott LG Navar 1995 Calcium activation mechanisms in the renal microvascular response to extracellular ATP Am J Physiol Renal, Fluid Electrolyte Physiol 268 F876 F884
77. SS Yiu X Zhao EW Inscho JD Imig 2003 12-Hydroxyeicosatetraenoic acid participates in angiotensin II afferent arteriolar vasoconstriction by activating L-type calcium channels J Lipid Res 44 2391 2399 12951362
78. N Miyata RJ Roman 2005 Role of 20-hydroxyeicosatetraenoic acid (20-HETE) in vascular system J Smooth Muscle Res 41 175 193 16258232
79. RJ Roman 2002 P-450 metabolites of arachidonic acid in the control of cardiovascular function Physiol Rev 82 131 185 11773611
80. KG Maier RJ Roman 2001 Cytochrome P450 metabolites of arachidionic acid in the control of renal function Curr Opin Nephrol Hypertens 10 81 87 11195057
81. XY Zhao EW Inscho M Bondlela JR Falck JD Imig 2001 The CYP450 hydroxylase pathway contributes to P2X receptor-mediated afferent arteriolar vasoconstriction Am J Physiol Heart Circ Physiol 281 H2089 H2096 11668070
82. X Zhao JR Falck VR Gopal EW Inscho JD Imig 2004 P2X receptor-stimulated calcium responses in preglomerular vascular smooth muscle cells involves 20-hydroxyeicosatetraenoic acid J Pharmacol Exp Ther 311 1211 1217 15316085
83. 2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase Physiol Rev 83 1325 1358 14506307
84. 2+ sensitization of the contractile apparatus in vascular smooth muscle J Pharmacol Sci 109 109 115
85. K Chitaley D Weber RC Webb 2001 RhoA/Rho-kinase, vascular changes, and hypertension Curr Hypertension Rep 3 139 144
86. A Cavarape J Bauer E Bartoli K Endlich N Parekh 2003 Effects of angiotensin II, arginine vasopressin and tromboxane A2 in renal vascular bed: role of rho-kinase Nephrol Dial Transplant 18 1764 1769 12937222
87. A Cavarape N Endlich R Assaloni E Bartoli M Steinhausen N Parekh K Endlich 2003 Rho-kinase inhibition blunts renal vasoconstriction induced by distinct signaling pathways in vivo J Am Soc Nephrol 14 37 45 12506136
88. EW Inscho AK Cook RC Webb 2009 Rho-kinase inhibition reduces pressure-mediated autoregulatory adjustments in afferent arteriolar diameter Am J Renal Physiol 296 F590 F597
89. M Jankowski K Szczepanska-Konkel L Kalinowski S Angielski 2003 Involvement of rho-kinase in P2Y-receptor-mediated contraction of renal glomeruli Biochem Biophys Res Commun 302 855 859 12646249
90. S Sakurada H Okamoto N Takuwa N Sugimoto Y Takuwa 2001 Rho activation in excitatory agonist-stimulated vascular smooth muscle Am J Physiol Cell Physiol 281 C571 C578 11443056
91. V Randriamboavonjy R Busse I Fleming 2003 20-HETE-induced contraction of small coronary arteries depends on the activation of rho-kinase Hypertension 41 801 12623999
92. 6 receptors are coupled to Rho and Rho kinase activation in vascular myocytes Am J Physiol Heart Circ Physiol 278 H1751 10843869
93. R Schubert VU Kalentchuk U Krien 2002 Rho kinase inhibition partly weakens myogenic reactivity in rat small arteries by changing calcium sensitivity Am J Physiol Heart Circ Physiol 283 H2288 12388214
94. Arendshorst WJ, Navar LG (1993) Renal circulation and glomerular hemodynamics. In: Schrier RW, Gottschalk C (eds) Diseases of the kidney. Little, Brown and Co, Boston, pp 65-117
95. A Just 2007 Mechanisms of renal blood flow autoregulation: dynamics and contributions Am J Physiol Regul Integr Comp Physiol 292 R1 R17 16990493
96. R Loutzenhiser K Griffin G Williamson A Bidani 2006 Renal autoregulation: new perspectives regarding the protective and regulatory roles of the underlying mechanisms Am J Physiol Regul Integr Comp Physiol 290 R1153 R1167 16603656
97. H Castrop 2007 Mediators of tubuloglomerular feedback regulation of glomerular filtration: ATP and adenosine Acta Physiologica 189 3 14 17280552
98. J Schnermann DZ Levine 2003 Paracrine factors in tubuloglomerular feedback: adenosine, ATP and nitric oxide Ann Rev Physiol 65 501 529
99. T Takenaka LM Harrison-Bernard EW Inscho PK Carmines LG Navar 1994 Autoregulation of afferent arteriolar blood flow in juxtamedullary nephrons Am J Physiol 267 F879 F887 7977792
100. V Vallon 2003 Tubuloglomerular feedback and the control of glomerular filtration rate News Physiol Sci 18 169 174 12869618
101. V Vallon B Muhlbauer H Osswald 2006 Adenosine and kidney function Physiol Rev 86 901 940 16816141
102. A Nishiyama LG Navar 2002 ATP mediates tubuloglomerular feedback Am J Physiol Regul Integr Comp Physiol 283 R273 R275 12069954
103. J Schnermann 2002 Adenosine mediates tubuloglomerular feedback Am J Physiol Regul Integr Comp Physiol 283 R276 R277 12069955
104. PD Bell JY Lapointe J Peti-Peterdi 2003 Macula densa cell signaling Ann Rev Physiol 65 481 500
105. P Komlosi A Fintha PD Bell 2004 Current mechanisms of macula densa cell signalling Acta Physiol Scand 181 463 469 15283759
106. PB Persson 2002 Renal blood flow autoregulation in blood pressure control Curr Opin Nephrol Hypertension 11 67 72
107. Bell PD, Komlosi P, Zhang Z (2008) ATP as a mediator of macula densa cell signalling. Pur Sig (in press)
108. 1 receptor blockade Am J Physiol 258 F553 F561 1969237
109. S Thomson DJ Bao A Deng V Vallon 2000 Adenosine formed by 5'-nucleotidase mediates tubuloglomerular feedback J Clin Invest 106 289 298 10903345
110. Y Ren S Arima OA Carretero S Ito 2002 Possible role of adenosine in macula densa control of glomerular hemodynamics Kidney Int 61 169 176 11786098
111. H Castrop Y Huang S Hashimoto D Mizel P Hansen F Theilig S Bachmann C Deng J Briggs J Schnermann 2004 Impairment of tubuloglomerular feedback regulation of GFR in ecto-5'-nucleotidase/CD73-deficient mice J Clin Invest 114 634 642 15343381
112. DY Huang V Vallon H Zimmermann P Koszalka J Schrader H Osswald 2006 Ecto-5'-nucleotidase (cd73)-dependent and -independent generation of adenosine participates in the mediation of tubuloglomerular feedback in vivo Am J Physiol Renal Physiol 291 F282 F288 16525161
113. MG Feng LG Navar 2007 Adenosine A2 receptor activation attenuates afferent arteriolar autoregulation during adenosine receptor saturation in rats Hypertension 50 744 749 17664389
114. S Hashimoto Y Huang J Briggs J Schnermann 2006 Reduced autoregulatory effectiveness in adenosine 1 receptor-deficient mice Am J Physiol Renal Physiol 290 F888 F891 16263804
115. 1 adenosine receptors in mice Am J Physiol Renal Physiol 293 F1489 F1500 17728380
116. 1 receptor-deficient mice Am J Physiol Regul Integr Comp Physiol 281 R1362 R1367 11641103
117. 1 receptors Proc Natl Acad Sci USA 98 9983 9988 11504952
118. V Vallon K Richter DY Huang T Rieg J Schnermann 2004 Functional consequences at the single-nephron level of the lack of adenosine A1 receptors and tubuloglomerular feedback in mice Pflugers Arch V448 214 221
119. AJ Premen JE Hall HL Mizelle JE Cornell 1985 Maintenance of renal autoregulation during infusion of aminophylline or adenosine Am J Physiol Renal Physiol 248 F366 F373
120. A Nishiyama DSA Majid M Walker III A Miyatake LG Navar 2001 Renal interstitial ATP responses to changes in arterial pressure during alterations in tubuloglomerular feedback activity Hypertension 37 753 759 11230369
121. PD Bell J-Y Lapointe R Sabirov S Hayashi J Peti-Peterdi K Manabe G Kovacs Y Okada 2003 Macula densa cell signaling involves ATP release through a maxi anion channel Proc Natl Acad Sci USA 100 4322 4327 12655045
122. P Komlosi J Peti-Peterdi AL Fuson A Fintha L Rosivall PD Bell 2004 Macula densa basolateral ATP release is regulated by luminal [NaCl] and dietary salt intake Am J Physiol Renal Physiol 286 F1054 F1058 14749255
123. R Liu PD Bell J Peti-Peterdi G Kovacs A Johansson AEG Persson 2002 Purinergic receptor signaling at the basolateral membrane of macula densa cells J Am Soc Nephrol 13 1145 1151 11961001
124. A Nishiyama KE Jackson DSA Majid M Rahman LG Navar 2006 Renal interstitial fluid ATP responses to arterial pressure and tubuloglomerular feedback activation during calcium channel blockade Am J Physiol Heart Circ Physiol 290 H772 H777 16214849
125. A Nishiyama DSA Majid KA Taher A Miyatake LG Navar 2000 Relation between renal interstitial ATP concentrations and autoregulation-mediated changes in renal vascular resistance Circ Res 86 656 662 10747001
126. D Casellas LG Navar 1984 In vitro perfusion of juxtamedullary nephrons in rats Am J Physiol Renal, Fluid Electrolyte Physiol 246 F349 F358
127. D Casellas PK Carmines LG Navar 1985 Microvascular reactivity of in vitro blood perfused juxtamedullary nephrons from rats Kidney Int 28 752 759 4087691
128. D Casellas R Taugner 1986 Renin status of the afferent arteriole and ultrastructure of the juxtaglomerular apparatus in "superficial" juxtamedullary nephrons from rats Ren Physiol 9 348 356 3299564
129. Inscho EW (2000) The in vitro blood perfused juxtamedullary nephron technique. In: Wang DH (ed) Methods in Molecular Medicine. Humana Press, Totowa, pp 435-449
130. M Walker III LM Harrison-Bernard AK Cook LG Navar 2000 Dynamic interaction between myogenic and TGF mechanisms in afferent arteriolar blood flow autoregulation Am J Physiol Renal Physiol 279 F858 F865 11053046
131. 1 knockout mice Acta Physiol Scand 181 445 453 15283757
132. H Ikenaga RW Fallet PK Carmines 1996 Contribution of tubuloglomerular feedback to renal arteriolar angiotensin II responsiveness Kidney Int 49 34 39 8770946
133. CF Sanchez-Ferrer RJ Roman DR Harder 1989 Pressure-dependent contraction of rat juxtamedullary afferent arterioles Circ Res 64 790 798 2702737
134. A Ichihara EW Inscho JD Imig LG Navar 1998 Neuronal nitric oxide synthase modulates rat renal microvascular function Am J Physiol Renal Physiol 274 F516 F524
135. KL Duchin LN Peterson TJ Burke 1977 Effect of furosemide on renal autoregulation Kidney Int 12 379 386 609187
136. FS Wright P Briggs 1977 Feedback regulation of glomerular filtration rate Am J Physiol Renal Physiol 233 F1 F7
137. LC Moore J Schnermann S Yarimizu 1979 Feedback mediation of SNGFR autoregulation in hydropenic and DOCA- and salt-loaded rats Am J Physiol Renal Physiol 237 F63 F74
138. J Schnermann J Briggs 1982 Concentration-dependent sodium choride transport as the signal in feedback control of glomerular filtration rate Kidney Int 22 S82 S89
139. D Casellas LC Moore 1990 Autoregulation and tubuloglomerular feedback in juxtamedullary glomerular arterioles Am J Physiol Renal Physiol 258 F660 F669
140. LC Moore D Casellas 1990 Tubuloglomerular feedback dependence of autoregulation in rat juxtamedullary afferent arterioles Kidney Int 37 1402 1408 2362399 (Pubitemid 20198020)
141. J Schnermann 1988 Effect of adenosine analogues on tubuloglomerular feedback responses Am J Physiol 255 F33 F42 3394811
142. J Peti-Peterdi 2006 Calcium wave of tubuloglomerular feedback Am J Physiol Renal Physiol 291 F473 F480 16495210
143. P Komlosi A Fintha PD Bell 2005 Renal cell-to-cell communication via extracellular ATP Physiology 20 86 90 15772296
144. i increase depends on nucleotide release and subsequent purinergic signaling in the intact nephron J Am Soc Nephrol 18 2062 2070 17554149
145. MB Hovater D Olteanu EL Hanson NL Cheng B Siroky A Fintha P Komlosi W Liu LM Satlin PD Bell BK Yoder EM Schwiebert 2008 Loss of apical monocilia on collecting duct principal cells impairs ATP secretion across the apical cell surface and ATP-dependent and flow-induced calcium signals Purinergic Signalling 4 155 170 18368523
146. WA Webber J Lee 1975 Fine structure of mammalian renal cilia Anat Rec 182 339 343 1155803
147. BK Kishore J Isaac M Fausther SR Tripp H Shi PS Gill N Braun H Zimmermann J Sevigny SC Robson 2005 Expression of NTPDase1 and NTPDase2 in murine kidney: relevance to regulation of P2 receptor signaling Am J Physiol Renal Physiol 288 F1032 F1043 15632415
148. I Sabolic O Culic S-H Lin D Brown 1992 Localization of ecto-ATPase in rat kidney and isolated renal cortical membrane vesicles Am J Physiol Renal Physiol 262 F217 F228
149. A Solini C Iacobini C Ricci P Chiozzi L Amadio F Pricci U Di Mario F Di Virgilio G Pugliese 2005 Purinergic modulation of mesangial extracellular matrix production: role in diabetic and other glomerular diseases Kidney Int 67 875 885 15698427
150. RM Vekaria DG Shirley J Sevigny RJ Unwin 2006 Immunolocalization of ectonucleotidases along the rat nephron Am J Physiol Renal Physiol 290 F550 F560 16189292
151. J Karczewska L Martyniec G Dzierzko J Stepinski S Angielski 2007 The relationship between constitutive ATP release and its extracellular metabolism in isolated rat kidney glomeruli J Physiol Pharmacol 58 321 333 17622700
152. J Satriano L Wead A Cardus A Deng GR Boss SC Thomson RC Blantz 2006 Regulation of ecto-5'-nucleotidase by NaCl and nitric oxide: potential roles in tubuloglomerular feedback and adaptation Am J Physiol Renal Physiol 291 F1078 F1082 16705150
153. T Takenaka H Okada Y Kanno T Inoue M Ryuzaki H Nakamoto H Kawachi F Shimizu H Suzuki 2006 Exogenous 5'-nucleotidase improves glomerular autoregulation in Thy-1 nephritic rats Am J Physiol Renal Physiol 290 F844 F853 16189293
154. Shirley DG, Vekaria RM, Sevigny J (2009) Ectonucleotidases and the kidney. Purinergic Signalling in press
155. T Takenaka T Inoue Y Kanno H Okada CE Hill H Suzuki 2008 Connexins 37 and 40 transduce purinergic signals mediating renal autoregulation Am J Physiol Reg Integr Comp Physiol 294 R1 R11
156. C Rüster G Wolf 2006 Renin-angiotensin-aldosterone system and progression of renal disease J Am Soc Nephrol 17 2985 2991 17035613
157. G Wolf 2006 Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-[beta] pathway Kidney Int 70 1914 1919 16985515
158. WP Anderson MM Kett KM Stevenson AJ Edgley KM Denton SM Fitzgerald 2000 Renovascular hypertension: Structural changes in the renal vasculature Hypertension 36 648 652 11040252
159. SM Fitzgerald RG Evans G Bergström WP Anderson 1999 Renal hemodynamic responses to intrarenal infusion of ligands for the putative angiotensin IV receptor in anesthetized rats J Cardiovasc Pharmacol 34 206 211 10445671
160. JD Imig EW Inscho 2002 Adaptations of the renal microcirculation to hypertension Microcirculation 9 315 328 12152107
161. EW Inscho PK Carmines AK Cook LG Navar 1990 Afferent arteriolar responsiveness to altered perfusion pressure in renal hypertension Hypertension 15 748 752 2351427
162. EW Inscho JD Imig PC Deichmann AK Cook 1999 Candesartan-Cilexetil protects against loss of autoregulatory efficiency in angiotensin II infused rats J Am Soc Nephrol 10 S178 S183 9892160
163. DW Ploth 1983 Angiotensin II-dependent renal mechanisms in two-kidney, one-clip renal vascular hypertension Am J Physiol Renal, Fluid Electrolyte Physiol 245 F131 F141
164. DW Ploth RN Roy WC Huang LG Navar 1981 Impaired renal blood flow and cortical pressure autoregulation in the contralateral kidney of Goldblatt hypertensive rats Hypertension 3 67 74 7203607
165. S Racasan JA Joles P Boer HA Koomans B Braam 2003 NO dependency of RBF and autoregulation in the spontaneously hypertensive rat Am J Physiol Renal Physiol 285 F105 F112 12631552
166. O Vonend CM Turner CM Chan A Loesch GC Dell'Anna KS Srai G Burnstock RJ Unwin 2004 Glomerular expression of the ATP-sensitive P2X receptor in diabetic and hypertensive rat models Kidney Int 66 157 166 15200422
167. WJ Welch 2002 Adenosine type 1 receptor antagonists in fluid retaining disorders Expert Opinion on Investigational Drugs 11 1553 1562 12437502
168. ML Graciano A Nishiyama K Jackson DM Seth RM Ortiz MC Prieto-Carrasquero H Kobori LG Navar 2007 Purinergic receptors contribute to early mesangial cell transformation and renal vessel hypertrophy during angiotensin II-induced hypertension Am J Physiol Renal Physiol 294 F161 F169 17989111
169. CT Wang SY Chin LG Navar 2000 Impairment of pressure-natriuresis and renal autoregulation in ANG II-infused hypertensive rats Am J Physiol Renal Physiol 279 F319 F325 10919852
170. JD Imig 2000 Afferent arteriolar reactivity to angiotensin II is enhanced during the early phase of angiotensin II hypertension Am J Hypertens 13 810 818 10933574
171. AK Bidani KA Griffin 2004 Pathophysiology of hypertensive renal damage: implications for therapy Hypertension 44 595 601 15452024