Macula Densa Cell Signaling

Annual Review of Physiology

Volumn 65, Issue , 2003, Pages 481-500

  Bell, P Darwin ^a   Lapointe, Jean Yves ^b   Peti Peterdi, János ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Cell to cell; Communication; Kidney; Renal hemodynamics; Tubuloglomerular feedback

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANION;

ADAPTATION; BASOLATERAL MEMBRANE; CALCIUM TRANSPORT; CELL MEMBRANE; CHLORIDE TRANSPORT; DEPOLARIZATION; FEEDBACK SYSTEM; GLOMERULUS BASEMENT MEMBRANE; GLOMERULUS FILTRATION; HEMODYNAMICS; IMAGING SYSTEM; ION EXCHANGE; ION TRANSPORT; KIDNEY CELL; KIDNEY DISTAL TUBULE; MACULA DENSA; MICROSCOPY; MOLECULAR BIOLOGY; MOLECULAR INTERACTION; MOLECULAR MECHANICS; NONHUMAN; PLASMA OSMOLALITY; POTASSIUM CONDUCTANCE; POTASSIUM TRANSPORT; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; SENSORY NERVE CELL; SIGNAL PROCESSING; SIGNAL TRANSDUCTION; SODIUM TRANSPORT; ANIMAL; CELL COMMUNICATION; CYTOLOGY; GLOMERULUS; HUMAN; JUXTAGLOMERULAR APPARATUS; KIDNEY CIRCULATION; PHYSIOLOGY; VASCULARIZATION;

ANIMALS; CELL COMMUNICATION; HUMANS; JUXTAGLOMERULAR APPARATUS; KIDNEY GLOMERULUS; RENAL CIRCULATION;

EID: 0038581902     PISSN: 00664278     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.physiol.65.050102.085730     Document Type: Review

References (97)

1. Navar LG, Inscho EW, Majid SA, Imig JD, Hamson-Bernard LM, Mitchell KD. 1996. Paracrine regulation of the renal microcirculation. Physiol. Rev. 76:425-536
2. Barajas L. 1979. Anatomy of the juxtaglomerular apparatus. Am. J. Physiol. Renal Physiol. 7:F333-F43
3. Navar LG, Ploth DW, Bell PD. 1980. Distal tubular feedback control of renal hemodynamics and autoregulation. Annu. Rev. Physiol. 49:557-71
4. Schnermann J, Traylor T, Yang T, Arend L, Huang YG, et al. 1998. Tubuloglomerular feedback: new concepts and developments. Kidney Int. 54:S40-S45
5. Greger R. 1988. Chloride transport in thick ascending limb, distal convolution and collecting duct. Annu. Rev. Physiol. 50:111-22
6. Reeves WB, Winters CJ, Andreoli TE. 2001. Chloride channels in the loop of Henle. Annu. Rev. Physiol. 63:631-45
7. LaPointe J-Y, Laamarti A, Bell PD. 1998. Ionic transport in macula densa cells. Kidney Int. 54:S58-S64
8. Ren Y, Garvin JL, Carretero OA. 2001. Efferent arteriole tubuloglomerular feedback in the renal nephron. Kidney Int. 59:222-29
9. Briggs JP, Schnermann J. 1987. The tubuloglomerular feedback mechanism: functional and biochemical aspects. Annu. Rev. Physiol. 49:251-73
10. Schnermann J, Levine DZ. 2003. Paracrine factors in tubuloglomerular feedback: adenosine, ATP, and nitric oxide. Annu. Rev. Physiol. 65:501-29
11. Wright FS, Schnermann J. 1974. Interference with feedback control of glomerular filtration rate by furosemide, triflocin, and cynamide. J. Clin. Invest. 53:1695-708
12. Bell PD, LaPointe J-Y. 1997. Characteristics of membrane transport processes of macula densa cells. Clin. Exp. Pharmacol. Physiol. 24:541-54
13. Kirk K, Bell PD, Barfuss D, Ribadeneira MD. 1985. Direct visualization of the isolated perfused renal macula densa. Am. J. Physiol. Renal Physiol. 248:F890-F94
14. Yang T, Huand YG, Singh I, Schnermann J, Briggs JP. 1996. Localization of bumetanide- and thiazide-sensitive Na-K-Cl cotransporters along the rat nephron. Am. J. Physiol. Renal Physiol. 271:F931-F39
15. Plata C, Meade P, Hall A, Welch RC, Vázquez N, et al. 2001. Alternatively spliced isoform of apical Na(+)-K(+)-Cl(-) cotransporter gene encodes a furosemide-sensitive Na(+)-Cl(-) cotransporter. Am. J. Physiol. Renal Physiol. 280:F574-F82
16. - cotransporter isoforms. J. Biol. Chem. 277:11001-12
17. Giménez I, Isenring P, Forbush B. 2002. Spatially distributed alternative splice variants of the renal Na-K-Cl cotransporter exhibit dramatically different affinities for the transported ions. J. Biol. Chem. 277:8767-70
18. LaPointe J-Y, Bell PD, Cardinal J. 1990. Direct evidence for an apical Na:2Cl:K co-transport in macula densa cells. Am. J. Physiol. Renal Physiol. 258:F1466-F69
19. Bell PD, Navar LG. 1982. Relationship between tubuloglomerular feedback responses and perfusate hypotonicity. Kidney Intern. 22:234-39
20. Bell PD, LaPointe J-Y, Cardinal J. 1989. Direct measurement of basolateral membrane potential in cells of the macula densa. Am. J. Physiol. Renal Physiol. 257:F463-F68
21. + cotransport. Pflügers Arch. 414:286-90
22. LaPointe J-Y, Bell PD, Hurst AM, Cardinal J. 1991. Basolateral ionic permeabilities of macula densa cells. Am. J. Physiol. Renal Physiol. 260:F856-F60
23. LaPointe J-Y, Laamarti A, Hurst AM, Fowler BC, Bell PD. 1995. Activation of Na:2Cl:K cotransport by luminal chloride in macula densa cells. Kidney Int. 47:752-57
24. Ren Y, Yu H, Wang H, Carretero OA, Garvin JL. 2001. Nystatin and valinomycin induce tubuloglomerular feedback. Am J. Physiol. Renal Physiol. 281:F1102-F8
25. Vallon V, Osswald H, Blantz RC, Thomson S. 1997. Potential role of luminal potassium in tubuloglomerular feedback. J. Am. Soc. Nephrol. 8:1831-37
26. Vallon V, Osswald H, Blantz RC, Thomson S. 1998. Luminal signal in tubuloglomerular feedback: what about potassium? Kidney Int. Suppl. 67:S177-79
27. Schnermann J. 1995. Effects of barium ions on tubuloglomerular feedback. Am. J. Physiol. Renal Physiol. 268:F960-F66
28. Xu JZ, Hall AE, Peterson LN, Bienkowski MJ, Eessalu TE, Hebert SC. 1997. Localization of the ROMK protein on apical membranes of rat kidney nephron segments. Am. J. Physiol. Renal Physiol. 273:F739-F48
29. Hebert SC. 1998. Roles of Na-K-2Cl and Na-Cl cotransporters and ROMK potassium channels in urinary concentrating mechanism. Am. J. Physiol. Renal Physiol. 275:F325-F27
30. Ecelbarger CA, Kim GH, Knepper MA, Liu J, Tate M, et al. 2001. Regulation of potassium channel Kir 1.1 (ROMK) abundance in the thick ascending limb of Henle's loop. J. Am. Soc. Nephrol. 12:10-18
31. Wang W. 1999. Regulation of the ROMK channel: interaction of the ROMK with associate proteins. Am. J. Physiol. Renal Physiol. 277: F826-F31
32. Hurst AM, LaPointe J-Y, Laamarti A, Bell PD. Basic properties and potential regulators of the apical K channel in macula densa cells. J. Gen. Physiol. 103:1055-70
33. Lorenz JN, Baird NR, Judd LM, Noonan WT, Andringa A, et al. 2002. Impaired renal NaCl absorption in mice lacking the potassium channel, a model for type II Bartter's syndrome. J. Biol. Chem. 277:37871-78
34. + channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice. J. Biol. Chem. 277: 37881-87
35. Fowler BC, Chang Y-S, Laamarti A, Higdon M, LaPointe J-Y, Bell PD. 1995. Evidence for apical sodium-proton exchange in macula densa cells. Kidney Int. 47:746-51
36. Orlowski J, Grinstein S. 1997. Na-H exchangers of mammalian cells. J. Biol. Chem. 272:22373-76
37. Amemiya M, Loffing J, Lotscher M, Kaissling B, Alpern RJ, Moe OW. 1995. Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb. Kidney Int. 48: 1206-15
38. + exchanger isoform NHE-1 in rabbit kidney. Am. J. Physiol. Renal Physiol. 263:F833-F40
39. + exchanger isoform NHE2 in rat kidney. Am. J. Physiol. Renal Physiol. 275:F379-F86
40. + exchanger isoform NHE4 in rat thick ascending limbs. Am. J. Physiol. Renal Physiol. 281:F707-F17
41. Vallon V, Schwark JR, Richter K, Hropot M. 2000. Role of Na(+)/H(+) exchanger NHE3 in nephron function: micropuncture studies with S3226, an inhibitor of NHE3. Am. J. Physiol. Renal Physiol. 278:F375-F79
42. + exchanger isoform 2 (NHE2) is expressed in the apical membrane of the medullary thick ascending limb. J. Membr. Biol. 160:85-90
43. Wang T, Hropot M, Aronson PS, Giebisch G. 2001. Role of NHE isoforms in mediating bicarbonate reabsorption along the nephron. Am. J. Physiol. Renal Physiol. 281:F1117-F22
44. Peti-Peterdi J, Chambrey R, Bebok Z, St John PL, Abrahamson DR, et al. 2000. Macula densa Na:H exchange activities mediated by apical NHE2 and basolateral NHE4 isoforms. Am. J. Physiol. Renal Physiol. 278: F452-F63
45. Lorenz JN, Schultheis PJ, Traynor T, Shull GE, Schnermann J. 1999. Micropuncture analysis of single-nephron function in NHE3-deficient mice. Am. J. Physiol. Renal Physiol. 277:F447-F53
46. + exchanger but not in mice lacking NHE2. Am. J. Physiol. Renal Physiol. 281:F718-F27
47. Salomonsson M, Gonzales E, Westerlund P, Persson AE. 1991. Chloride concentration in macula densa and cortical thick ascending limb cells. Kidney Int. 32:S51-S54
48. Peti-Peterdi J, Bebok Z, LaPointe J-Y, Bell PD. 2002. Cytosolic [Na+] regulation in macula densa cells: novel role for an apical H:K ATPase. Am. J. Physiol. Renal Physiol. 282:F324-F29
49. Codina M, Pressley TA, DuBose TD. 1999. The colonic H, K-ATPase functions as a Na-dependent K (NH4)-ATPase in apical membranes from rat distal colon. J. Biol. Chem. 274:19693-98
50. Cougnon M, Bouyer P, Planelles G, Jaisser F. 1998. Does the colonic H,K ATPase also act as a Na,K-ATPase? Proc. Natl. Acad. Sci. USA 95:6516-20
51. Verlander JW, Moudy RM, Campbell WG, Cain BD, Wingo CS. 2001. Immunohistochemical localization of H-K-ATPase alpha(2c)-subunit in rabbit kidney. Am. J. Physiol. Renal Physiol. 281:F357-F65
52. Wetzel RK, Sweadner KJ. 2001. Immunocytochemical localization of Na-K-ATPase and subunits in rat kidney. Am. J. Physiol. Renal Physiol. 281:F531
53. Peti-Peterdi J, Bell PD. 2000. Cytosolic [Ca2+] signaling pathway in macula densa cells. Am. J. Physiol. Renal Physiol. 277:F472-F76
54. Salomonsson M, Gonzalez E, Westerlund P, Persson AE. 1991. Intracellular cytosolic free calcium concentration in the macula densa and in ascending llimb cells at different luminal concentrations of sodium chloride and with added furoesemide. Acta Physiol. Scand. 142:283-90
55. Lapointe J-Y, Bell PD, Sabirov R, Okada Y. 2002. Calcium-activated non-selective cation channel in macula densa cells Am. J. Physiol. Renal Physiol. Submitted
56. 55a. Montell C, Birnbaumer L, Flockerzi V. 2002. The TRP channels, a remarkably functional family. Cell 108:595-98
57. Liu R, Bell PD, Peti-Peterdi J, Kovacs G, Johansson A, Persson AEG. 2002. Identification of purinergic receptors on rabbit macula densa cells. J. Am. Soc. Nephrol. 13:1145-51
58. Mitchell KD, Navar LG. 1988. Enhanced tubuloglomerular feedback during pertitubular infusion of angiotensins I and II. Am. J. Physiol. Renal Physiol. 255:F383-F90
59. Traynor T, Yang T, Huang YG, Krege JH, Briggs JP, et al. 1999. Tubuloglomerular feedback in ACE-deficient mice. Am. J. Physiol. Renal Physiol. 276:F751-F57
60. Yamamoto T, Hayashi K, Matsuda H, Kubota E, Tanaka H, et al. 2001. In vivo visualization of angiotensin II- and tubuloglomerular feedback-mediated renal vasoconstriction. Kidney Int. 60:364-69
61. Schnermann JB, Traynor T, Yang T, Huang YG, Oliverio MI, et al. 1997. Absence of tubuloglomerular feedback responses in AT1A receptor-deficient mice . Am. J. Physiol. Renal Physiol. 273:F315-F20
62. Ren Y, Carretero OA, Ito S. 1996. Influence of NaCl concentration at the macula densa on angiotensin II-induced constriction of the afferent arteriole. Hypertension 27:649-52
63. 1 receptor in adult rat kidney using monoclonal antibody. Am. J. Physiol. Renal Physiol. 273:F170-F77
64. Wang H, Garvin JL, Carretero OA. 2001. Angiotensin II enhances tubuloglomerular feedback via luminal AT(1) receptors on the macula densa. Kidney Int. 60:1851-57
65. Peti-Peterdi J, Bell PD. 1998. Regulation of macula densa Na:H exchange by angiotensin II. Kidney Int. 54:2021-28
66. Bell PD, Peti-Peterdi J. 1999. Angiotensin II stimulates macula densa basolateral sodium/hydrogen exchange via type 1 angiotensin II receptor. J. Am. Soc. Nephrol. 10:S225-29
67. Kovacs G, Peti-Peterdi J, Rosivall L, Bell PD. 2002. Angiotensin II directly stimulates macula densa Na:2Cl:K cotransport via apical AT1 receptors. Am. J. Physiol. Renal Physiol. 282:F301-F6
68. Laamarti MA, Bell PD, Lapointe J-Y. 1998. Transport and regulatory properties of the apical Na:K:2Cl cotransporter of macula densa cells. Am. J. Physiol. Renal Physiol. 275:F703-F9
69. Welch WJ, Wilcox CS, Thomson SC. 1999. Nitric oxide and tubuloglomerular feedback. Semin. Nephrol. 19:251-62
70. Ren Y, Garvin JL, Carretero OA. 2000. Role of macula densa nitric oxide and cGMP in the regulation of tubuloglomerular feedback. Kidney Int. 54:2053-60
71. Welch WJ, Wilcox CS. 2002. What is brain nitric oxide synthase doing in the kidney? Curr. Opin. Nephrol. Hypertens. 11:109-15
72. Vallon V, Traynor T, Barajas L, Huang YG, Briggs JP, Schnermann J. 2001. Feedback control of glomerular vascular tone in neuronal nitric oxide synthase knockout mice. J. Am. Soc. Nephrol. 12:1599-606
73. Harris RC, Breyer MD. 2001. Physiological regulation of cyclooxygenase-2 in the kidney. Am. J. Physiol. Renal Physiol. 281:F1-F11
74. Ortiz PA, Garvin JL. 2001. NO inhibits NaCl absorption by rat thick ascending limb through activation of cGMP-stimulated phosphodiesterase. Hypertension 37:467-71
75. Yang T, Park JM, Arend L, Huang Y, Topaloglu R, et al. 2000. Low chloride stimulation of prostaglandin E2 release and cyclooxygenase-2 expression in a mouse macula densa cell line. J. Biol. Chem. 275:37922-29
76. Peti-Peterdi J, Morishima-Peterdi S, Bell PD, Okada Y. 2002. Two-photon excitation fluorescence imaging of the living juxtaglomerular apparatus. Am. J. Physiol. Renal Physiol. 283:F197-F201
77. Gonzalez E, Salomonsson M, Muller-Suur C, Persson AE. 1988. Measurements of macula densa cell volume changes in isolated and perfused rabbit cortical thick ascending limb. II. Apical and basolateral cell osmotic water permeabilities. Acta Physiol. Scand. 133:159-66
78. Pricam C, Humbert F, Perrelet A, Orci L. 1974. Gap junctions in mesangial and lacis cells. J. Cell. Biol. 63:349-54
79. Taugner R, Schiller A, Kaissling B, Kriz W. 1978. Gap junctions coupling between the JGA and glomerular tuft. Cell Tissue Res. 186:279-85
80. Traynor T, Yang T, Huang YG, Arend L, Oliverio MI, et al. 1998. Inhibition of adenosine-1 receptor-mediated preglomerular vasoconstriction in AT1A receptor-deficient mice. Am. J. Physiol. Renal Physiol. 275:F922-27
81. Sun D, Samuelson LC, Yang T, Huang Y, Paliege A, et al. 2001. Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors. Proc. Natl. Acad. Sci. USA 98:9983-88
82. Brown R, Ollerstam A, Johansson B, Skott O, Gebre-Medhin S, et al. 2001. Abolished tubuloglomerular feedback and increased plasma renin in adenosine A1receptor-deficient mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281:R1362-R67
83. Persson PB. 2001. Tubuloglomerular feedback in adenosine A1 receptor-deficient mice . Am. J. Physiol. Regul. Integr. Comp. Physiol. 281:R1361
84. Ren Y, Arima S, Carretero OA, Ito S. 2002. Possible role of adenosine in macula densa control of glomerular hemodynamics. Kidney Int. 61:169-76
85. Thomson S, Bao D, Deng A, Vallon V. 2000. Adenosine formed by 5′-nucleotidase mediates tubuloglomerular feedback. J. Clin. Invest. 106:289-98
86. Nishiyama A, Navar LG. 2002. ATP mediates tubuloglomerular feedback. Am. J. Physiol. Regul. Integr. Comp. Physiol. 283:R273-R75
87. Schnermann J. 2002. Adenosine mediates tubuloglomerular feedback. Am. J. Physiol. Regul. Integr. Comp. Physiol. 283:R276-R77
88. + response of rat mesangial cells to ATP analogues. Eur. J. Pharmacol. 369:107-12
89. Iijima K, Moore LC, Goligorsky MS. 1991. Syncytial organization of cultured mesangial cells. Am. J. Physiol. Renal Physiol. 260:F848-F55
90. Mitchell KD, Navar LG. 1993. Modulation of tubuloglomerular feedback responsiveness by extracellular ATP. Am. J. Physiol. Renal Physiol. 264:F458-F66
91. Inscho EW, Cook AK, Navar LG. 1996. Pressure-mediated vasoconstriction of juxtamedullary afferent arterioles involves P2-purinoceptor activation. Am. J. Physiol. Renal Physiol. 271:F1077-F85
92. Inscho EW, Cook AK, Mui V, Miller J. 1998. Direct assessment of renal microvascular responses to P2-purinoceptor agonists. Am. J. Physiol. Renal Physiol. 274:F218-F27
93. Nishiyama A, Majid DS, Taher KA, Miyatake A, Navar LG. 2000. Relation between renal interstitial ATP concenrations and autoregulation-mediated changes in renal vascular resistance. Circ. Res. 86:656-62
94. Bell PD, Lapointe J-Y, Sabirov R, Hayashi S, Peti-Peterdi J, et al. 2002. Macula densa signaling involves ATP release through a maxi-anion channel. Proc. Natl Acad. Sci. USA. Submitted
95. Dutta AK, Okada Y, Sabirov RZ. 2002. Regulation of an ATP-conductive large-conductance anion channel and swelling-induced ATP release by arachidonic acid. J. Physiol. 542:803-16
96. Sabirov RZ, Dutta AK, Okada Y. 2001. Volume-dependent ATP-conductive large-conductance anion channel as a pathway for swelling-induced ATP release. J. Gen. Physiol. 118:251-66
97. Ren Y, Carretero, Garvin JL. 2002. Role of mesangial cells and gap junctions in tubuloglomerular feedback. Kidney Int. 62:525-31