Ecto-5′-nucleotidase (cd73)-dependent and -independent generation of adenosine participates in the mediation of tubuloglomerular feedback in vivo

American Journal of Physiology - Renal Physiology

Volumn 291, Issue 2, 2006, Pages

  Dan, Yang Huang ^a   Vallon, Volker ^b   Zimmermann, Herbert ^c   Koszalka, Patricia ^d   Schrader, Jürgen ^e   Osswald, Hartmut ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GOETHE UNIVERSITY   (Germany)

^d MEDICAL UNIVERSITY OF GDANSK   (Poland)

^e HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Micropuncture; Stop flow pressure; Tubular reabsorption

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE; ADENOSINE A1 RECEPTOR ANTAGONIST; ECTO 5' NUCLEOTIDASE; POTASSIUM ION; PURINE P2X RECEPTOR; SODIUM ION; ADENOSINE A1 RECEPTOR; POTASSIUM; PURINE P2 RECEPTOR; PURINE P2X1 RECEPTOR; SODIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEEDBACK SYSTEM; FEMALE; GLOMERULUS FILTRATION RATE; HENLE LOOP; HISTOCHEMISTRY; IN VIVO STUDY; KIDNEY CLEARANCE; KIDNEY DISTAL TUBULE; KIDNEY PERFUSION; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE ABSORPTION; MALE; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PUNCH BIOPSY; ABSORPTION; ANIMAL; BLOOD PRESSURE; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; GLOMERULUS; KIDNEY TUBULE; METABOLIC CLEARANCE RATE; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; SIGNAL TRANSDUCTION;

5'-NUCLEOTIDASE; ABSORPTION; ADENOSINE; ANIMALS; BLOOD PRESSURE; FEEDBACK, BIOCHEMICAL; FEMALE; GENE EXPRESSION REGULATION; GLOMERULAR FILTRATION RATE; KIDNEY GLOMERULUS; KIDNEY TUBULES; MALE; METABOLIC CLEARANCE RATE; MICE; MICE, KNOCKOUT; POTASSIUM; RECEPTOR, ADENOSINE A1; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION; SODIUM;

EID: 33746651517     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00113.2005     Document Type: Article

References (39)

1. Bell PD, Lapointe JY, Sabirov R, Hayashi S, Peti-Peterdi J, Manabe K, Kovacs G, and Okada Y. Macula densa cell signaling involves ATP release through a maxi anion channel. Proc Natl Acad Sci USA 100: 4322-4327, 2003.
2. Braun N, Zhu Y, Krieglstein J, Culmsee C, and Zimmermann H. Upregulation of the enzyme chain hydrolyzing extracellular ATP after transient forebrain ischemia in the rat. J Neurosci 18: 4891-4900, 1998.
3. 1 receptor-deficient mice. Am J Physiol Regul Integr Comp Physiol 281: R1362-R1367, 2001.
4. Bucheimer RE and Linden J. Purinergic regulation of epithelial transport. J Physiol 555: 311-321, 2004.
5. Castrop H, Huang Y, Hashimoto S, Mizel D, Hansen P, Theilig F, Bachmann S, Deng C, Briggs J, and Schnermann J. Impairment of tubuloglomerular feedback regulation of GFR in ecto-5′-nucleotidase/CD73-deficient mice. J Clin Invest 114: 634-642, 2004.
6. Damer S, Niebel B, Czeche S, Nickel P, Ardanuy U, Schmalzing G, Rettinger J, Mutschler E, and Lambrecht G. NF279: a novel and selective antagonist of P2X receptor-mediated responses. Eur J Pharmacol 350: R5-R6, 1998.
7. Dyrberg T, Baekkeskov S, and Lernmark A. Specific pancreatic beta-cell surface antigens recognized by a xenogenic antiserum. J Cell Biol 94: 472-477, 1982.
8. Hansen PB and Schnermann J. Vasoconstrictor and vasodilator effects of adenosine in the kidney. Am J Physiol Renal Physiol 285: F590-F599, 2003.
9. + elimination in the sgk1-knockout mouse. J Am Soc Nephrol 15: 885-891, 2004.
10. Huang DY, Osswald H, and Vallon V. Eukaliuric diuresis and natriuresis in response to the KATP channel blocker U37883A: micropuncture studies on the tubular site of action. Br J Pharmacol 127: 1811-1818, 1999.
11. Huang DY, Osswald H, and Vallon V. Intratubular application of sodium azide inhibits loop of Henle reabsorption and tubuloglomerular feedback response in anesthetized rats. Naunyn Schmiedebergs Arch Pharmacol 358: 367-373, 1998.
12. Inscho EW, Cook AK, Imig JD, Vial C, and Evans RJ. Renal autoregulation in P2X1 knockout mice. Acta Physiol Scand 181: 445-453, 2004.
13. Inscho EW, Cook AK, Imig JD, Vial C, and Evans RJ. Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior. J Clin Invest 112: 1895-1905, 2003.
14. Jackson EK and Dubey RK. The extracellular cyclic AMP-adenosine pathway in renal physiology. Annu Rev Physiol 66: 571-599, 2004.
15. Jackson EK and Dubey RK. Role of the extracellular cAMP-adenosine pathway in renal physiology. Am J Physiol Renal Physiol 281: F597-F612, 2001.
16. 7 receptors. Eur J Pharmacol 387: 245-252, 2000.
17. Koszalka P, Ozuyaman B, Huo Y, Zernecke A, Flogel U, Braun N, Buchheiser A, Decking UK, Smith ML, Sevigny J, Gear A, Weber AA, Molojavyi A, Ding Z, Weber C, Ley K, Zimmermann H, Godecke A, and Schrader J. Targeted disruption of cd73/ecto-5′-nucleotidase alters thromboregulation and augments vascular inflammatory response. Circ Res 95: 814-821, 2004.
18. Lambrecht G, Damer S, Niebel B, Czeche S, Nikel P, Rettinger J, Schmalzing G, and Mutschler E. Novel ligands for P2 receptor subtypes in innervated tissues. Prog Brain Res 120: 107-117, 1999.
19. Le Hir M and Kaissling B. Distribution and regulation of renal ecto-5′-nucleotidase: implications for physiological functions of adenosine. Am J Physiol Renal Fluid Electrolyte Physiol 264: F377-F387, 1993.
20. Lohse MJ, Klotz KN, Lindenborn-Fotinos J, Reddington M, Schwabe U, and Olsson RA. 8-Cyclopentyl-1,3-dipropylxanthine (DPCPX)-a selective high affinity antagonist radioligand for A1 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol 336: 204-210, 1987.
21. Marxer-Meier A, Hegyi I, Loffing J, and Kaissling B. Postnatal maturation of renal cortical peritubular fibroblasts in the rat. Anat Embryol (Berl) 197: 143-153, 1998.
22. Nishiyama A and Navar LG. ATP mediates tubuloglomerular feedback. Am J Physiol Regul Integr Comp Physiol 283: R273-R275, 2002.
23. Osswald H, Muhlbauer B, and Schenk F. Adenosine mediates tubuloglomerular feedback response: an element of metabolic control of kidney function. Kidney Int 32: S128-S131, 1991.
24. Osswald H, Nabakowski G, and Hermes H. Adenosine as a possible mediator of metabolic control of glomerular filtration rate. Int J Biochem 12: 263-267, 1980.
25. Osswald H, Muhlbauer B, and Vallon V. Adenosine and tubuloglomerular feedback. Blood Purif 15: 243-252, 1997.
26. Ren YL, Garvin JL, Liu R, and Carretero OA. Role of macula densa adenosine triphosphate (ATP) in tubuloglomerular feedback. Kidney Int 66: 1479-1485, 2004.
27. 1 receptor. Neuropharmacology 39: 2044-2053, 2000.
28. 1 receptors for the diuretic and natriuretic action of the methylxanthines theophylline and caffeine. J Pharmacol Exp Ther 313: 403-409, 2005.
29. Savic V, Blanchard A, Vlahovic P, Stefanovic V, Ardaillou N, and Ardaillou R. Cyclic adenosine monophosphate-stimulating agents induce ecto-5′-nucleotidase activity and inhibit DNA synthesis in rat cultured mesangial cells. Arch Biochem Biophys 290: 202-206, 1991.
30. Schnermann J. Adenosine mediates tubuloglomerular feedback. Am J Physiol Regul Integr Comp Physiol 283: R276-R277, 2002.
31. Schnermann J, Weihprecht H, and Briggs JP. Inhibition of tubuloglomerular feedback during adenosine A1 receptor blockade. Am J Physiol Renal Fluid Electrolyte Physiol 258: F553-F561, 1990.
32. Sun D, Samuelson LC, Yang T, Huang Y, Paliege A, Saunders T, Briggs J, and Schermann J. Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors. Proc Natl Acad Sci USA 98: 9983-9988, 2001.
33. Thomson S, Bao D, Deng A, and Vallon V. Adenosine formed by 5′-nucleotidase mediates tubuloglomerular feedback. J Clin Invest 106: 289-298, 2000.
34. Thomson SC, Deng A, Bao D, Satriano J, Blantz RC, and Vallon V. Ornithine decarboxylase, kidney size, and the tubular hypothesis of glomerular hyperfiltration in experimental diabetes. J Clin Invest 107: 217-224, 2001.
35. Vallon V. Tubuloglomerular feedback and the control of glomerular filtration rate. News Physiol Sci 18: 169-174, 2003.
36. Vallon V, Richter K, Huang DY, Rieg T, and Schnermann J. Functional consequences at the single-nephron level of the lack of adenosine A1 receptors and tubuloglomerular feedback in mice. Pflügers Arch 448: 214-21, 2004.
37. Weihprecht H, Lorenz JN, Briggs JP, and Schnermann J. Synergistic effects of angiotensin and adenosine in the renal microvasculature. Am J Physiol Renal Fluid Electrolyte Physiol 266: F227-F239, 1994.
38. Wulff P, Vallon V, Huang DY, Volkl H, Yu F, Richter K, Jansen M, Schlunz M, Klingel K, Loffing J, Kauselmann G, Bosl MR, Lang F, and Kuhl D. Impaired renal Na(+) retention in the sgk1-knockout mouse. J Clin Invest 110: 1263-1268, 2002.
39. Zimmermann H. 5′-Nucleotidase: molecular structure and functional aspects. Biochem J 285: 345-365, 1992.