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Volumn 123, Issue 4, 1998, Pages 719-729

P2U-receptor mediated endothelium-dependent but nitric oxide-independent vascular relaxation

Author keywords

Dilatation; EDHF; Endothelium; Nitric oxide; P2Y , P2U purinoceptor; Pyrimidine receptor; Vascular reactivity

Indexed keywords

2 METHYLTHIOADENOSINE TRIPHOSPHATE; 2-METHYLTHIO-ATP; ACETYLCHOLINE; ADENOSINE; ADENOSINE TRIPHOSPHATE; DRUG DERIVATIVE; INDOMETACIN; NITRIC OXIDE; NUCLEOTIDE; PURINE P2 RECEPTOR; PURINE P2Y2 RECEPTOR; URIDINE TRIPHOSPHATE;

EID: 0031990815     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701660     Document Type: Article
Times cited : (45)

References (36)
  • 1
    • 0027403233 scopus 로고
    • Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor NO through a radical reaction
    • AKAIKE, T., YOSHIDA, M., MIYAMOTO, Y., SATO, K., KOHNO, M., SASAMOTO, K., MIYAZAKA, K., UEDA, S. & MAEDA, H. (1993). Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor NO through a radical reaction. Biochemistry, 32, 827 - 832.
    • (1993) Biochemistry , vol.32 , pp. 827-832
    • Akaike, T.1    Yoshida, M.2    Miyamoto, Y.3    Sato, K.4    Kohno, M.5    Sasamoto, K.6    Miyazaka, K.7    Ueda, S.8    Maeda, H.9
  • 2
    • 0027935877 scopus 로고
    • Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase
    • ARCHER, S.L., HUANG, J.M.C., HAMPL, V., NELSON, D.P., SCHULTZ, P.J. & WEIR, E.K. (1994). Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc. Natl. Acad. Sci. U.S.A., 91, 7583 - 7587.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 7583-7587
    • Archer, S.L.1    Huang, J.M.C.2    Hampl, V.3    Nelson, D.P.4    Schultz, P.J.5    Weir, E.K.6
  • 3
    • 0028090109 scopus 로고
    • Display of the characteristics of the endothelium-derived hyperpolarising factor by a cytochrome P450-derived arachidonic acid metabolite on the coronary microcirculation
    • BAUERSACHS J., HECKER, M. & BUSSE, R. (1994). Display of the characteristics of the endothelium-derived hyperpolarising factor by a cytochrome P450-derived arachidonic acid metabolite on the coronary microcirculation. Br. J. Pharmacol., 113, 1548 - 1553.
    • (1994) Br. J. Pharmacol. , vol.113 , pp. 1548-1553
    • Bauersachs, J.1    Hecker, M.2    Busse, R.3
  • 4
    • 0028220671 scopus 로고
    • Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle
    • BOLOTINA, V.M., NAJIBI, S., PALACINO, J.J., PAGANO, P.J. & COHEN, R.A. (1994). Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature. 368, 850 - 853.
    • (1994) Nature , vol.368 , pp. 850-853
    • Bolotina, V.M.1    Najibi, S.2    Palacino, J.J.3    Pagano, P.J.4    Cohen, R.A.5
  • 6
    • 0030051805 scopus 로고    scopus 로고
    • Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factor
    • CAMPBELL, W. B., GEBREMEDHIN, D., PRATT, P.F. & HARDER, D.R. (1996). Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factor. Circ. Res., 78, 415 - 423.
    • (1996) Circ. Res. , vol.78 , pp. 415-423
    • Campbell, W.B.1    Gebremedhin, D.2    Pratt, P.F.3    Harder, D.R.4
  • 7
    • 0028819714 scopus 로고
    • Molecular cloning and fuctional expression of a novel P2 nucleotide receptor
    • CHANG, K., HANAOKA, K., KUMADA, M. & TAKUWA, Y. (1995). Molecular cloning and fuctional expression of a novel P2 nucleotide receptor. J. Biol. Chem., 270, 26152 - 26158.
    • (1995) J. Biol. Chem. , vol.270 , pp. 26152-26158
    • Chang, K.1    Hanaoka, K.2    Kumada, M.3    Takuwa, Y.4
  • 8
    • 0025765434 scopus 로고
    • Endothelium-dependent hyperpolarization elicited by adenine compounds in rabbit carotid artery
    • CHEN, G. & SUZUKI, H. (1991). Endothelium-dependent hyperpolarization elicited by adenine compounds in rabbit carotid artery. Am. J. Physiol., 260, H1037 - H1042.
    • (1991) Am. J. Physiol. , vol.260
    • Chen, G.1    Suzuki, H.2
  • 9
    • 0024238725 scopus 로고
    • Acctylcholine releases endothelial-derived hyperpolarising factor and EDRF from rat blood vessels
    • CHEN, G., SUZUKI, H. & WESTON, A.H. (1988). Acctylcholine releases endothelial-derived hyperpolarising factor and EDRF from rat blood vessels. Br. J. Pharmacol., 95, 1165 - 1174.
    • (1988) Br. J. Pharmacol. , vol.95 , pp. 1165-1174
    • Chen, G.1    Suzuki, H.2    Weston, A.H.3
  • 10
    • 0025760997 scopus 로고
    • Hyperpolarization of arterial smooth muscle induced by endothelial humoral substances
    • CHEN, G., YAMAMOTO, Y., MIWA, K. & SUZUKI, H. (1991). Hyperpolarization of arterial smooth muscle induced by endothelial humoral substances. Am. J. Physiol., 260, H1888 - H1892.
    • (1991) Am. J. Physiol. , vol.260
    • Chen, G.1    Yamamoto, Y.2    Miwa, K.3    Suzuki, H.4
  • 11
    • 0029794001 scopus 로고    scopus 로고
    • Modulation of endothelium-dependent hyperpolarisation and relaxation to acctylcholine in rat mesenteric artery by cytochrome P450 enzyme activity
    • CHEN, G.C. & CHEUNG, D.W. (1996). Modulation of endothelium-dependent hyperpolarisation and relaxation to acctylcholine in rat mesenteric artery by cytochrome P450 enzyme activity. Circ. Res., 79, 827 - 833.
    • (1996) Circ. Res. , vol.79 , pp. 827-833
    • Chen, G.C.1    Cheung, D.W.2
  • 12
    • 0029563956 scopus 로고
    • Cloning and functional expression of a human uridine nucleotide receptor
    • COMMUNI, D., PIROTTON, S., PARMENTIER, M. & BOEYNAEMS, J.-M. (1995a). Cloning and functional expression of a human uridine nucleotide receptor. J. Biol. Chem., 270, 30849 - 30852.
    • (1995) J. Biol. Chem. , vol.270 , pp. 30849-30852
    • Communi, D.1    Pirotton, S.2    Parmentier, M.3    Boeynaems, J.-M.4
  • 13
    • 0028985442 scopus 로고
    • Coexpression of P2Y and P2U receptors on aortic endothelial cells. Comparison of cell localisation and signaling pathways
    • COMMUNI, D., RASPE, E., PIROTTON, S. & BOEYNAEMS, J.-M. (1995b). Coexpression of P2Y and P2U receptors on aortic endothelial cells. Comparison of cell localisation and signaling pathways. Circ. Res., 76, 191 - 198.
    • (1995) Circ. Res. , vol.76 , pp. 191-198
    • Communi, D.1    Raspe, E.2    Pirotton, S.3    Boeynaems, J.-M.4
  • 14
    • 0029146579 scopus 로고
    • Nitric oxide produced by endothelial cells increases production of ecosanoids through activation of prostaglandin H synthase
    • DAVIDGE, S.T., BAKER, P.N., MCLAUGHLIN, M.K.& ROBERTS, J.M. (1995). Nitric oxide produced by endothelial cells increases production of ecosanoids through activation of prostaglandin H synthase. Circ. Res., 77, 274 - 283.
    • (1995) Circ. Res. , vol.77 , pp. 274-283
    • Davidge, S.T.1    Baker, P.N.2    Mclaughlin, M.K.3    Roberts, J.M.4
  • 15
    • 0029907118 scopus 로고    scopus 로고
    • Effects of cytochrome P450 inhibitors on potassium currents and mechanical activity in rat portal vein
    • EDWARDS, G., ZYGMUNT, P.M., HÖGESTÄTT, E.D. & WESTON, A.H. (1996). Effects of cytochrome P450 inhibitors on potassium currents and mechanical activity in rat portal vein. Br. J. Pharmacol., 119, 691 - 701.
    • (1996) Br. J. Pharmacol. , vol.119 , pp. 691-701
    • Edwards, G.1    Zygmunt, P.M.2    Högestätt, E.D.3    Weston, A.H.4
  • 17
    • 0026536407 scopus 로고
    • Decreased endothelial-dependent hyperpolarizations to acetylcholine in smooth muscle of the mesenteric artery of spontaneously hypertensive rats
    • FUJII, K., TOMINAGA, M., OHMORI, S., KOBAYASHI, K., KOGA, T., TAKATA, Y. & FUJISHIMA, M. (1992). Decreased endothelial-dependent hyperpolarizations to acetylcholine in smooth muscle of the mesenteric artery of spontaneously hypertensive rats. Circ. Res., 70, 660 - 669.
    • (1992) Circ. Res. , vol.70 , pp. 660-669
    • Fujii, K.1    Tominaga, M.2    Ohmori, S.3    Kobayashi, K.4    Koga, T.5    Takata, Y.6    Fujishima, M.7
  • 18
    • 0024390169 scopus 로고
    • Endothelium-derived relaxing and contracting factors
    • FURCHGOTT, R.F. & VANHOUTTE, P.M. (1989). Endothelium-derived relaxing and contracting factors. FASEB J., 3, 2007 - 2018.
    • (1989) FASEB J. , vol.3 , pp. 2007-2018
    • Furchgott, R.F.1    Vanhoutte, P.M.2
  • 19
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • FURCHGOTT, R.F. & ZAWADZKI, J.V. (1980). The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 288, 373 - 376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 20
    • 0026569512 scopus 로고
    • Evidence that nitric oxide does not mediate the hyperpolarization and relaxation to acetylcholine in the rat small mesenteric artery
    • GARLAND, C.J. & MCPHERSON, G.A. (1992). Evidence that nitric oxide does not mediate the hyperpolarization and relaxation to acetylcholine in the rat small mesenteric artery. Br. J. Pharmacol., 105, 429 - 435.
    • (1992) Br. J. Pharmacol. , vol.105 , pp. 429-435
    • Garland, C.J.1    Mcpherson, G.A.2
  • 21
    • 0028835749 scopus 로고
    • Endothelium-dependent hyperpolarization: A role in the control of vascular tone
    • GARLAND, C.J., PLANE, F., KEMP, B.K. & COCKS, T.M. (1995). Endothelium-dependent hyperpolarization: a role in the control of vascular tone. Trends Pharmacol. Sci., 16, 23 - 30.
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 23-30
    • Garland, C.J.1    Plane, F.2    Kemp, B.K.3    Cocks, T.M.4
  • 22
    • 0020663886 scopus 로고
    • Mechanical properties of rat cerebral arteries as studied by a sensitive device for recording of mechanical activity in isolated small blood vessels
    • HÖGESTÄTT, E., ANDERSSON, K.-E. & EDVINSSON, L. (1983). Mechanical properties of rat cerebral arteries as studied by a sensitive device for recording of mechanical activity in isolated small blood vessels. Acta Physiol. Scand., 117, 49 - 61.
    • (1983) Acta Physiol. Scand. , vol.117 , pp. 49-61
    • Högestätt, E.1    Andersson, K.-E.2    Edvinsson, L.3
  • 23
    • 0024239369 scopus 로고
    • Endothelium-dependent hyperpolarization of smooth muscle cells in rabbit femoral arteries is not mediated by EDRF (nitric oxide)
    • HUANG, A.H., BUSSE, R. & BASSENGE, E. (1988). Endothelium-dependent hyperpolarization of smooth muscle cells in rabbit femoral arteries is not mediated by EDRF (nitric oxide). Naunyn-Schmiedeberg's Arch. Pharmacol., 338, 438 - 442.
    • (1988) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.338 , pp. 438-442
    • Huang, A.H.1    Busse, R.2    Bassenge, E.3
  • 24
    • 0028082723 scopus 로고
    • Heterogeneous populations of K+ channels mediate EDRF release to flow but not agonists in rabbit aorta
    • HUTCHESSON, I.R. & GRIFFITH, T.M. (1994). Heterogeneous populations of K+ channels mediate EDRF release to flow but not agonists in rabbit aorta. Am. J. Physiol., 266, H590 - H596.
    • (1994) Am. J. Physiol. , vol.266
    • Hutchesson, I.R.1    Griffith, T.M.2
  • 25
    • 0026524499 scopus 로고
    • Purinergic relaxation and hyperpolarisation in guinea pig and rabbit coronary artery: Role of the endothelium
    • KEEF, K.D. PASCO, J.S. & ECKMAN, D.M. (1992). Purinergic relaxation and hyperpolarisation in guinea pig and rabbit coronary artery: role of the endothelium. J. Pharmacol. Exp. Ther., 260, 592 - 600.
    • (1992) J. Pharmacol. Exp. Ther. , vol.260 , pp. 592-600
    • Keef, K.D.1    Pasco, J.S.2    Eckman, D.M.3
  • 26
    • 0023280003 scopus 로고
    • Heterogeneous distribution of muscarinic receptors in the rabbit saphenous artery
    • KOMORI, K. & SUZUKI, H. (1987). Heterogeneous distribution of muscarinic receptors in the rabbit saphenous artery. Br. J. Pharmacol., 92, 657 - 664.
    • (1987) Br. J. Pharmacol. , vol.92 , pp. 657-664
    • Komori, K.1    Suzuki, H.2
  • 27
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, patophysiology and pharmacology
    • MONCADA, S., PALMER, R.M.J. & HIGGS, E.A. (1991). Nitric oxide: physiology, patophysiology and pharmacology. Pharmacol. Rev., 43, 109 - 142.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 28
    • 0026065276 scopus 로고
    • Further subclassification of ATP receptors based on agonist studies
    • O'CONNOR, S.E., DAINTY, I.A. & LEFF, P. (1991). Further subclassification of ATP receptors based on agonist studies. Trends Pharmocol. Sci., 12, 137 - 141.
    • (1991) Trends Pharmocol. Sci. , vol.12 , pp. 137-141
    • O'Connor, S.E.1    Dainty, I.A.2    Leff, P.3
  • 29
    • 0023198721 scopus 로고
    • Nitric-oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • PALMER, R.M.J., FERRIGE, A.G. & MONCADA, S. (1987). Nitric-oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature, 327, 524 - 526.
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.J.1    Ferrige, A.G.2    Moncada, S.3
  • 30
    • 0028334212 scopus 로고
    • Differential regulation of inositol 1,4,5-triphosphate by coexisting P2Y-purinoceptors and nucleotide receptors on bovine aortic endothelial cells
    • PURKISS, J.R., WILKINSON, G.F. & BOARDER, M.R. (1994). Differential regulation of inositol 1,4,5-triphosphate by coexisting P2Y-purinoceptors and nucleotide receptors on bovine aortic endothelial cells. Br. J. Pharmacol., 111, 723 - 728.
    • (1994) Br. J. Pharmacol. , vol.111 , pp. 723-728
    • Purkiss, J.R.1    Wilkinson, G.F.2    Boarder, M.R.3
  • 31
    • 0028005370 scopus 로고
    • Characterization of ATP-induced vasodilatation in the human forearm vascular bed
    • RONGEN, G.A., SMITHS, P. & THIEN, T. (1994). Characterization of ATP-induced vasodilatation in the human forearm vascular bed. Circulation, 90, 1891 - 1898.
    • (1994) Circulation , vol.90 , pp. 1891-1898
    • Rongen, G.A.1    Smiths, P.2    Thien, T.3
  • 32
    • 0025339053 scopus 로고
    • Hyperpolarization and relaxation of arterial smooth muscle caused by nitric oxide derived from the endothelium
    • TARE, M., PARKINGTON, H.C., COLEMAN, H.A., NEILD, T.O. & DUSTING, G.J. (1990). Hyperpolarization and relaxation of arterial smooth muscle caused by nitric oxide derived from the endothelium. Nature, 346, 69 - 71.
    • (1990) Nature , vol.346 , pp. 69-71
    • Tare, M.1    Parkington, H.C.2    Coleman, H.A.3    Neild, T.O.4    Dusting, G.J.5
  • 33
    • 0023785420 scopus 로고
    • Endothelium-derived hyperpolarising factor: A new endogenous inhibitor from the vascular endothelium
    • TAYLOR, S.G. & WESTON, A.H. (1988). Endothelium-derived hyperpolarising factor: a new endogenous inhibitor from the vascular endothelium. Trends Pharmacol. Sci., 9, 272 - 274.
    • (1988) Trends Pharmacol. Sci. , vol.9 , pp. 272-274
    • Taylor, S.G.1    Weston, A.H.2
  • 35
    • 0028101768 scopus 로고
    • Endothelium-dependent relaxation resistant to Nω-nitro-L-arginine in the rat hepatic artery and aorta
    • ZYGMUNT, P.M., GRUNDEMAR, L. & HÖGESTÄTT, E.D. (1994). Endothelium-dependent relaxation resistant to Nω-nitro-L-arginine in the rat hepatic artery and aorta. Acta Physiol. Scand., 152, 107 - 114.
    • (1994) Acta Physiol. Scand. , vol.152 , pp. 107-114
    • Zygmunt, P.M.1    Grundemar, L.2    Högestätt, E.D.3
  • 36
    • 0029912917 scopus 로고    scopus 로고
    • Role of potassium channels in endothelium-dependent relaxation resistant to nitroarginine in the rat hepatic artery
    • ZYGMUNT, P.M. & HÖGESTÄTT, E.D. (1996). Role of potassium channels in endothelium-dependent relaxation resistant to nitroarginine in the rat hepatic artery. Br. J. Pharmacol., 117, 1600 - 1606.
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 1600-1606
    • Zygmunt, P.M.1    Högestätt, E.D.2


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