Renal vascular reactivity to P2-purinoceptor activation in spontaneously hypertensive rats

Pharmacology

Volumn 60, Issue 1, 2000, Pages 47-50

  Fernández, Oscar ^a   Wangensteen, Rosemary ^a   Osuna, Antonio ^a   Vargas, Félix ^a,b  

^a HOSPITAL UNIVERSITARIO VIRGEN DE LAS NIEVES   (Spain)

^b UNIVERSITY OF GRANADA   (Spain)

Author keywords

2 methylthio ATP; Isolated kidney; P(2X) purinoceptors; P(2Y) purinoceptors; Spontaneously hypertensive rats; , methylene ATP

Indexed keywords

2 METHYLTHIOADENOSINE TRIPHOSPHATE; ACETYLCHOLINE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; BARIUM CHLORIDE; CYCLIC GMP; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; PURINE P2 RECEPTOR; PURINE P2X RECEPTOR; PURINE P2Y RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DOSE RESPONSE; HYPERTENSION; ISOLATED KIDNEY; KIDNEY BLOOD VESSEL; KIDNEY PERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VASODILATATION;

EID: 17644443533     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000028346     Document Type: Article

References (24)

1. Burnstock G, Kennedy C: A dual function for adenosine 5′-triphosphate in the regulation of vascular tone. Cir Res 1985;58:319-330.
2. Olson RA, Pearson JD: Cardiovascular purinoceptors. Physiol Rev 1990;70:761-845.
3. Gordon JL: Extracellular ATP: Effects, sources and fate. Biochem J 1986;233:309-319.
4. 2-purinoceptors in the cardiovascular system. Circulation 1991;84:1-14.
5. 2 purinergic receptors. J Pharrnacol Exp Ther 1993;265: 334-338.
6. Vargas F, Osuna A, Fernández-Rivas A: Renal vascular reactivity to ATP in hyper- and hypothyroid rats. Experientia 1996;52:225-229.
7. Vargas F, Moreno MRR, Osuna A: Renal vascular reactivity to ATP in ageing rats. Med Sci Res 1996;24:263-265.
8. Mombouli JV, Vanhoutte PM: Purinergic endothelium-dependent and -independent contractions in rat aorta. Hypertension 1993;22: 577-583.
9. Folkow B: Physiological aspects of primary hypertension. Physiol Rev 1982;62:347-504.
10. Folkow B, Hallback M, Lundgren Y, Weiss L: Background of increased flow resistance and vascular reactivity in spontaneously hypertensive rats. Acta Physiol Scand 1970;80:93-106.
11. Collis MG, Vanhoutte PM: Vascular reactivity of isolated perfused kidneys from male and female spontaneously hypertensive rats. Cir Res 1977;41:759-767.
12. Berecek KH, Slocker M, Gross F: Changes in renal vascular reactivity at various stages of deoxycorticosterone hypertension in rats. Circ Res 1980;46:619-624.
13. 2-Purinergic receptors on vascular smooth muscle and endothelium. Hypertension 1992; 19:286-289.
14. Burton GA, Haylor J, Jonge A: Renal sensitivity to endothelium-derived-relaxing-factor-mediated vasodilation in the spontaneously hypertensive rat. Clin Sci 1991;80:435-441.
15. Cachofeiro V, Nasjletti A: Increased vascular responsiveness to bradykinin in kidneys of spontaneously hypertensive rats: Effect of N-nitro-L-arginine. Hypertension 1991;18:683-688.
16. Lockette W, Otsuka Y, Carretero O: The loss of endothelium-dependent vascular relaxation in hypertension. Hypertension 1986:8(suppl II): II-61-II-66.
17. Miller MJS, Pinto A, Mullane KM: Impaired endothelium-dependent relaxation in rabbits subjected to aortic coarctation hypertension. Hypertension 1987;10:164-170.
18. Bell DR, Bohr DF: Endothelium in functional aortic changes of coarctation hypertension. Am J Physiol 1991;260:H1187-H1193.
19. Winquist RJ, Blunting PB, Baskin EP, Wallace AA: Decreased endothelium-dependent relaxation in New Zealand genetic hypertensive rats. J Hypertens 1984;2:541-545.
20. Tesfamariam B, Halpern W: Endothelium-dependent and endothelium-independent vasodilation in resistance arteries from hypertensive rats. Hypertension 1988;11:440-444.
21. Panza JA, Quyumi AA, Brush JE Jr, Epstein SE: Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. N Engl J Med 1990;323:22-27.
22. Hollenberg NK, Adams DF: The renal circulation in hypertensive disease. Am J Med 1976; 60:773-782.
23. Boegehold MA: Reduced influence of nitric oxide in artcriolar tone in hypertensive Dahl rats. Hypertension 1992;19:290-295.
24. Nava E, Farré AL, Moreno C, Casado S, Moreau P, Consentino F, Lüscher TF: Alterations in the nitric oxide pathway in the spontaneously hypertensive rats. J Hypertens 1998;3:385-391.