Adenosine A2 receptor activation attenuates afferent arteriolar autoregulation during adenosine receptor saturation in rats

Hypertension

Volumn 50, Issue 4, 2007, Pages 744-749

  Feng, Ming Guo ^a   Navar, L Gabriel ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine receptors; ATP; Kidney; Microcirculation; Renal autoregulation; Tubuloglomerular feedback

Indexed keywords

ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2 RECEPTOR; ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE RECEPTOR; XANTHINE DERIVATIVE;

ANIMAL EXPERIMENT; ARTERIOLE; AUTOREGULATION; BLOOD VESSEL DIAMETER; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; CONTROLLED STUDY; MALE; MEASUREMENT; NEPHRON; NONHUMAN; PERFUSION PRESSURE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; RAT; VASOCONSTRICTION; VASODILATATION;

ADENOSINE; ANIMALS; ARTERIOLES; BLOOD PRESSURE; DOSE-RESPONSE RELATIONSHIP, DRUG; HOMEOSTASIS; KIDNEY; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A1; RECEPTORS, ADENOSINE A2; THEOBROMINE; VASOCONSTRICTION; XANTHINES;

EID: 34548824072     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.107.094961     Document Type: Conference Paper

References (39)

1. Fredholm BB, Abbracchio MP, Burnstock G, Dubyak GR, Harden TK, Jacobson KA, Schwabe U, Williams M. Toward a revised nomenclature for P1 and P2 receptors. Trends Pharmacol Sci. 1997;18:79-82.
2. Ongini E, Fredholm BB. Pharmacology of adenosine A2A receptors. Trends Pharmacol Sci. 1996;17:364-372.
3. Modlinger PS, Welch WJ. Adenosine A1 receptor antagonists and the kidney. Curr Opin Nephrol Hypertens. 2003;12:497-502.
4. Navar LG, Inscho EW, Majid SA, Imig JD, Harrison-Bernard LM, Mitchell KD. Paracrine regulation of the renal microcirculation. Physiol Rev. 1996;76:425-536.
5. Lee HT, Emala CW. Characterization of adenosine receptors in human kidney proximal tubule (HK-2) cells. Exp Nephrol. 2002;10:383-392.
6. Zou AP, Wu F, Li PL, Cowley AW Jr. Effect of chronic salt loading on adenosine metabolism and receptor expression in renal cortex and medulla in rats. Hypertension 1999;33:511-516.
7. Jackson EK, Zhu C, Tofovic SP. Expression of adenosine receptors in the preglomerular microcirculation. Am J Physiol Renal Physiol. 2002;283:F41-F51.
8. Hansen PB, Hashimoto S, Oppermann M, Huang Y, Briggs JP, Schnermann J. Vasoconstrictor and vasodilator effects of adenosine in the mouse kidney due to preferential activation of A1 or A2 adenosine receptors. J Pharmacol Exp Ther. 2005;315:1150-1157.
9. Spielman WS, Thompson CI. A proposed role for adenosine in the regulation of renal hemodynamics and renin release. Am J Physiol Renal Fluid Electrolyte Physiol. 1982;242:F423-F435.
10. Spielman WS, Britton SL, Fiksen-Olsen MJ. Effect of adenosine on the distribution of renal blood flow in dogs. Circ Res.1980;46:449-456.
11. Tagawa H, Vander AJ. Effects of adenosine compounds on renal function and renin secretion in dogs. Circ Res. 1970;26:327-338.
12. Nishiyama A, Inscho EW, Navar LG. Interactions of adenosine A1 and A2a receptors on renal microvascular reactivity. Am J Physiol Renal Physiol. 2001;280:F406-F414.
13. Vallon V, Mühlbauer B, Osswald H. Adenosine and kidney function. Physiol Rev. 2006;86:901-940.
14. Osswald H, Spielman WS, Knox FG. Mechanism of adenosine-mediated decreases in glomerular filtration rate in dogs. Circ Res. 1978;43:465-469.
15. Pawlowska D, Granger JP, Knox FG. Effects of adenosine infusion into renal interstitium on renal hemodynamics. Am J Physiol Renal Fluid Electrolyte Physiol. 1978;252:F678-F682.
16. Berthold H, Just A, Kirchheim HR, Osswald H, Ehmke H. Renal hemodynamic responses to exogenous and endogenous adenosine in conscious dogs. J Physiol. 1998;510:321-330.
17. Tagawa H, Vander AJ. Effects of adenosine compounds on renal function and renin secretion in dogs. Circ Res. 1970;26:327-338.
18. Carroll MA, Doumad AB, Li J, Cheng MK, Falck JR, McGiff JC. Adenosine2A receptor vasodilation of rat preglomerular microvessels is mediated by EETs that activate the cAMP/PKA pathway. Am J Physiol Renal Physiol. 2006;291:F155-F161.
19. Imig JD, Falck JR, Inscho EW. Contribution of cytochrome P450 epoxygenase and hydroxylase pathways to afferent arteriolar autoregulatory responsiveness. Br J Pharmacol. 1999;127:1399-1405.
20. Hashimoto S, Huang Y, Briggs J, Schnermann J. Reduced autoregulatory effectiveness in adenosine 1 receptor-deficient mice. Am J Physiol Renal Physiol. 2006;290:F888-F891.
21. Takenaka T, Harrison-Bernard LM, Inscho EW, Carmines PK, Navar LG. Autoregulation of afferent arteriolar blood flow in juxtamedullary nephrons. Am J Physiol. 1994;267:F879-F887.
22. Inscho EW, Cook AK, Imig JD, Vial C, Evans RJ. Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior. J Clin Invest. 2003;112:1895-1905.
23. Nishiyama A, Navar LG. ATP mediates tubuloglomerular feedback. Am J Physiol Regul Integr Comp Physiol. 2002;283:R273-R275.
24. Ibarrola AM, Inscho EW, Vari RC, Navar LG. Influence of adenosine receptor blockade on renal function and renal autoregulation. J Am Soc Nephrol. 1991;2:991-999.
25. Nonaka, H, Ichimura M, Takeda M, Kanda T, Shimada J, Suzuki F, Kase H. KW-3902, a selective high affinity antagonist for adenosine A1 receptors. Br J Pharmacol. 1996;117:1645-1652.
26. Seale TW, Abla KA, Shamim MT, Carney JM, Daly JW. 3,7-Dimethyl-1- propargylxanthine: a potent and selective in vivo antagonist of adenosine analogs. Life Sci. 1988;43:1671-1684.
27. Zou AP, Nithipatikom K, Li PL, Cowley AW. Role of renal medullary adenosine in the control of blood flow and sodium excretion. Am J Physiol. 1999;276:R790-R798.
28. Wengert M, Berto C, Kaufman J, Leão-Ferreira LR, Paes-de-Carvalho R, Lopes AG, Caruso-Neves C. Stimulation of the proximal tubule Na+-ATPase activity by adenosine A(2A) receptor. Int J Biochem Cell Biol. 2005;37:155-165.
29. Feng MG, Navar LG. Angiotensin II-mediated constriction of afferent and efferent arterioles involves T-type Ca2+ channel activation. Am J Nephrol. 2004;24:641-648.
30. Feng MG, Navar LG. Nitric oxide synthase inhibition activates L and T-type Ca2+ channels in afferent and efferent arterioles. Am J Physiol Renal Physiol. 2006;290:F873-F879.
31. Feng MG, Li M, Navar LG. T-type calcium channels in the regulation of afferent and efferent arterioles in rats. Am J Physiol Renal Physiol. 2004;286:F331-F337.
32. Hansen PB, Castrop H, Briggs J, Schnermann J. Adenosine induces vasoconstriction through Gi-dependent activation of phospholipase C in isolated perfused afferent arterioles of mice. J Am Soc Nephrol. 2003; 14: 2457-2465.
33. Gerwins P, Fredholm BB. Activation of adenosine A1 and bradykinin receptors increases protein kinase C and phospholipase D activity in smooth muscle cells. Naunyn-Schmiedebergs Arch Pharmacol. 1995;351:186-193.
34. Shim JO, Shin CY, Lee TS, Yang SJ, An JY, Song HJ, Kim TH, Huh IH, Sohn UD. Signal transduction mechanism via adenosine A1 receptor in the cat esophageal smooth muscle cells. Cell Signal. 2002;14:365-372.
35. Herve, D, Levi-Strauss M, Marey-Semper I, Verney C, Tassin JP, Glowinski J, Girault JA. G(olf) and Gs in rat basal ganglia: possible involvement of G(olf) in the coupling of dopamine D1 receptor with adenylyl cyclase. J Neurosci. 1993;13:2237-2248.
36. Sun D, Samuelson LC, Yang T, Huang Y, Paliege A, Saunders T, Briggs J, Schnermann J. Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors. Proc Natl Acad Sci U S A. 2001;98:9983-9988.
37. Bell PD, Lapointe J-Y, Sabirov R, Hayashi S, Peti-Peterdi J, Manabe K, Kovacs G, Okada Y. Macula densa cell signaling involves ATP release through a maxi anion channel. Proc Natl Acad Sci U S A. 2003;100:4322-4327.
38. Brown R, Ollerstam A, Johansson B, Skøtt O, Fredholm B, Persson AE. Abolished tubuloglomerular feedback and increased plasma renin in adenosine A1 receptor-deficient mice. Am J Physiol Regulatory Integrative Comp Physiol. 2001;281:R1362-R1367.
39. Ren Y, Garvin JL, Liu R, Carretero OA. Role of macula densa adenosine triphosphate (ATP) in tubuloglomerular feedback. Kidney Int. 2004;66:1479-1485.