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Volumn 51, Issue 1, 1996, Pages 23-29

Variability in the rate of 6-mercaptopurine methylation in the erythrocytes, liver and kidney in an Italian population

Author keywords

6 Mercaptopurine; Adults; Erythrocytes; Kidney; Liver; Newborns; Polymorphism; Thiopurine methyltransferase

Indexed keywords

MERCAPTOPURINE; THIOPURINE METHYLTRANSFERASE;

EID: 0029782591     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050155     Document Type: Article
Times cited : (18)

References (37)
  • 1
    • 0026443183 scopus 로고
    • Pancytopenia related to azathioprine: An enzyme deficiency caused by common genetic polymorphism: A review
    • Anstey A, Lennard L, Mayou SC, Kirby JD (1992) Pancytopenia related to azathioprine: an enzyme deficiency caused by common genetic polymorphism: a review. J Roy Soc Med 85: 752-756
    • (1992) J Roy Soc Med , vol.85 , pp. 752-756
    • Anstey, A.1    Lennard, L.2    Mayou, S.C.3    Kirby, J.D.4
  • 2
    • 0002538947 scopus 로고
    • Antineoplastic agents
    • Goodman A, Gilman A, Rall AW, Nies AS, Taylor P(eds). McGraw-Hill. New York
    • Calabresi P, Chabner AB (1992) Antineoplastic agents. In: Goodman A, Gilman A, Rall AW, Nies AS, Taylor P(eds). The pharmacological basis of therapy. 8th edn. McGraw-Hill. New York, pp 1209-1263
    • (1992) The Pharmacological Basis of Therapy. 8th Edn. , pp. 1209-1263
    • Calabresi, P.1    Chabner, A.B.2
  • 3
    • 0026717661 scopus 로고
    • The importance of thiopurine methyltransferase activity for the use of azathioprine in transplant recipients
    • Chocair PR, Duley JA, Simmonds HA, Cameron JS (1992) The importance of thiopurine methyltransferase activity for the use of azathioprine in transplant recipients. Transplantation 53: 1051-1056
    • (1992) Transplantation , vol.53 , pp. 1051-1056
    • Chocair, P.R.1    Duley, J.A.2    Simmonds, H.A.3    Cameron, J.S.4
  • 4
    • 9544258636 scopus 로고
    • Methylation reaction
    • Evans DAP, (ed) Cambridge Universit Press, Cambridge
    • Evans DAP (1993) Methylation reaction. In: Evans DAP, Genetic factors in drug therapy (ed) Cambridge Universit Press, Cambridge, pp 330-345
    • (1993) Genetic Factors in Drug Therapy , pp. 330-345
    • Evans, D.A.P.1
  • 5
    • 0025837127 scopus 로고
    • Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia
    • Evans WE, Horner M, Chu YQ, Kalwinsky D, Roberts MW (1991) Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia. J Ped 119:985-989
    • (1991) J Ped , vol.119 , pp. 985-989
    • Evans, W.E.1    Horner, M.2    Chu, Y.Q.3    Kalwinsky, D.4    Roberts, M.W.5
  • 6
    • 0025910714 scopus 로고
    • Importance of 6-mercaptopurine dose in lymphoblastic leukaemia
    • Hale JP, Lilleyman JS (1991) Importance of 6-mercaptopurine dose in lymphoblastic leukaemia. Arch Dis Child 66:462-466
    • (1991) Arch Dis Child , vol.66 , pp. 462-466
    • Hale, J.P.1    Lilleyman, J.S.2
  • 8
    • 0028826952 scopus 로고
    • Higher activity of polymorphic thiopurine S-methyltransferase in erythrocytes from neonates compared to adults
    • McLeod HL, Krynetsky EY, Wiliams JA, Evans WE (1995) Higher activity of polymorphic thiopurine S-methyltransferase in erythrocytes from neonates compared to adults. Pharmacogenetics 5:281-286
    • (1995) Pharmacogenetics , vol.5 , pp. 281-286
    • McLeod, H.L.1    Krynetsky, E.Y.2    Wiliams, J.A.3    Evans, W.E.4
  • 9
    • 0027394372 scopus 로고
    • Thiopurine methyltransferase activity in a sample population of black subjects in Florida
    • Jones CD, Smart C, Titus A, Blyden G, Dorvil M, Nwadike N (1993) Thiopurine methyltransferase activity in a sample population of black subjects in Florida. Clin Pharmacol Ther 53: 348-535
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 348-535
    • Jones, C.D.1    Smart, C.2    Titus, A.3    Blyden, G.4    Dorvil, M.5    Nwadike, N.6
  • 10
    • 0027410849 scopus 로고
    • Identification of factors regulating thiopurine methyltransferase activity in a Norwegian population
    • Klemetsdal B, Straume B, Wist E, Aarbakke J (1993) Identification of factors regulating thiopurine methyltransferase activity in a Norwegian population. Eur J Clin Pharmacol 44: 147-152
    • (1993) Eur J Clin Pharmacol , vol.44 , pp. 147-152
    • Klemetsdal, B.1    Straume, B.2    Wist, E.3    Aarbakke, J.4
  • 12
    • 0027372372 scopus 로고
    • Gender differences in red blood cell thiopurine methyltransferase activity
    • Klemetsdal B, Wist E, Aarbakke J (1993) Gender differences in red blood cell thiopurine methyltransferase activity. Scand J Clin Lab Invest 53:747-749
    • (1993) Scand J Clin Lab Invest , vol.53 , pp. 747-749
    • Klemetsdal, B.1    Wist, E.2    Aarbakke, J.3
  • 14
    • 0027165518 scopus 로고
    • Thiopurine S-methyltransferase activity in a Chinese population
    • Lee EJD, Kalow W (1993) Thiopurine S-methyltransferase activity in a Chinese population. Clin Pharmacol Ther 54:28-33
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 28-33
    • Lee, E.J.D.1    Kalow, W.2
  • 15
    • 0027524983 scopus 로고
    • Congenital thiopurine methyltransferase deficiency and 6-mercaptopurine toxicity during treatment for acute lymphoblastic leukaemia
    • Lennard L, Gibson BES, Nicole T, Lilleyman JS (1993) Congenital thiopurine methyltransferase deficiency and 6-mercaptopurine toxicity during treatment for acute lymphoblastic leukaemia. Arch Dis Child 69:577-579
    • (1993) Arch Dis Child , vol.69 , pp. 577-579
    • Lennard, L.1    Gibson, B.E.S.2    Nicole, T.3    Lilleyman, J.S.4
  • 16
    • 0025331198 scopus 로고
    • Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia
    • Lennard F, Lilleyman JS, Van Loon J, Weinshilboum RW (1990) Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia. Lancet 336:225-229
    • (1990) Lancet , vol.336 , pp. 225-229
    • Lennard, F.1    Lilleyman, J.S.2    Van Loon, J.3    Weinshilboum, R.W.4
  • 17
    • 0023119219 scopus 로고
    • Thiopurine pharmacogenetics in leukaemia: Correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations
    • Lennard L, Van Loon J, Lilleyman, JS, Weinshilboum, RM (1987) Thiopurine pharmacogenetics in leukaemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations. Clin Pharmacol Ther 41:18-25
    • (1987) Clin Pharmacol Ther , vol.41 , pp. 18-25
    • Lennard, L.1    Van Loon, J.2    Lilleyman, J.S.3    Weinshilboum, R.M.4
  • 19
    • 0027285234 scopus 로고
    • Azathioprine-indueed myelosuppression in thiopurine methyltransferase deficient heart transplant recipient
    • McLeod HF, Miller DR, Evans WE (1993) Azathioprine-indueed myelosuppression in thiopurine methyltransferase deficient heart transplant recipient. Lancet 341:1151
    • (1993) Lancet , vol.341 , pp. 1151
    • McLeod, H.F.1    Miller, D.R.2    Evans, W.E.3
  • 20
    • 0008791365 scopus 로고
    • Human methyltransferases. Classification and metabolic profile of the major forms. The point of view of the Clinical Pharmacologist
    • Pacifici GM, Fracchia GN. (eds). Commission of the European Communities, Luxembourg
    • Pacifici GM, Fracchia GN (1995) Human methyltransferases. Classification and metabolic profile of the major forms. The point of view of the Clinical Pharmacologist. In: Pacifici GM, Fracchia GN. (eds). "Advances of drug metabolism in manCommission of the European Communities, Luxembourg, pp 461-493
    • (1995) Advances of Drug Metabolism in Man , pp. 461-493
    • Pacifici, G.M.1    Fracchia, G.N.2
  • 21
    • 0027136703 scopus 로고
    • Interindividual variability of phenol- and catechol- sulphotransferase in platelets from adults and newborns
    • Pacifici GM, Marchi G (1993) Interindividual variability of phenol- and catechol- sulphotransferase in platelets from adults and newborns. Br J Clin Pharmacol 36:593-597
    • (1993) Br J Clin Pharmacol , vol.36 , pp. 593-597
    • Pacifici, G.M.1    Marchi, G.2
  • 22
    • 0027165545 scopus 로고
    • S-methylation in human intestine: Differential distribution of the microsomal thiol methyltransferase and cytosolic thiopurine methyltransferase along the human bowel
    • Pacifici GM, Romiti P, Santerini S, Giuliani L (1993) S-methylation in human intestine: differential distribution of the microsomal thiol methyltransferase and cytosolic thiopurine methyltransferase along the human bowel. Xenobiotica 23: 671-679
    • (1993) Xenobiotica , vol.23 , pp. 671-679
    • Pacifici, G.M.1    Romiti, P.2    Santerini, S.3    Giuliani, L.4
  • 24
    • 0026336203 scopus 로고
    • Thiopurine Methyltransferase in humans: Development and tissue distribution
    • Pacifici GM, Romiti P, Giuliani L, Rane A (1991) Thiopurine Methyltransferase in humans: development and tissue distribution. Dev Pharmacol Ther 17:16-23
    • (1991) Dev Pharmacol Ther , vol.17 , pp. 16-23
    • Pacifici, G.M.1    Romiti, P.2    Giuliani, L.3    Rane, A.4
  • 27
    • 9444280322 scopus 로고
    • Hematology of the newborn
    • Beutler E, Erslev AJ, Lichtman MA (eds) Williams WJ, McGraw-Hill New York
    • Schwartz E, Gill FM (1983) Hematology of the newborn. In: Beutler E, Erslev AJ, Lichtman MA (eds) Williams WJ, Hematology, 3rd ed. McGraw-Hill New York, pp 37-47
    • (1983) Hematology, 3rd Ed. , pp. 37-47
    • Schwartz, E.1    Gill, F.M.2
  • 28
    • 0027401302 scopus 로고
    • Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient
    • Schutz E, Gummert J, Mohr F, Oellerich M (1993) Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient. Lancet 341:436
    • (1993) Lancet , vol.341 , pp. 436
    • Schutz, E.1    Gummert, J.2    Mohr, F.3    Oellerich, M.4
  • 29
    • 0027173780 scopus 로고
    • Thiopurine-methyl-transferase activity to assess azathioprine myelotoxicity in renal transplant recipients
    • Soria-Royer C, Legendre C, Mircheva J, Premel S, Beaune P, Kreis H (1993) Thiopurine-methyl-transferase activity to assess azathioprine myelotoxicity in renal transplant recipients. Lancet 341:1953-1954
    • (1993) Lancet , vol.341 , pp. 1953-1954
    • Soria-Royer, C.1    Legendre, C.2    Mircheva, J.3    Premel, S.4    Beaune, P.5    Kreis, H.6
  • 30
    • 0026907122 scopus 로고
    • Human thiopurine methyltransferase pharmacogenetics: Biochemical properties, liver-erythrocyte correlation and presence of isoenzymes
    • Szumlanski CL, Scott MC, Weinshilboum RM (1992) Human thiopurine methyltransferase pharmacogenetics: biochemical properties, liver-erythrocyte correlation and presence of isoenzymes. Pharmacogenetics 2:148-159
    • (1992) Pharmacogenetics , vol.2 , pp. 148-159
    • Szumlanski, C.L.1    Scott, M.C.2    Weinshilboum, R.M.3
  • 32
    • 0026779179 scopus 로고
    • Human kidney thiopurine methyltransferase photoaffinity labelling with S-adenosyl-L-methionine
    • Van Loon J, Szumlanski CL, Weinshilboum EM (1992) Human kidney thiopurine methyltransferase photoaffinity labelling with S-adenosyl-L-methionine. Biochem Pharmacol 44:775-785
    • (1992) Biochem Pharmacol , vol.44 , pp. 775-785
    • Van Loon, J.1    Szumlanski, C.L.2    Weinshilboum, E.M.3
  • 33
    • 0025187322 scopus 로고
    • Thiopurine methyltransferase isozymes in human renal tissue
    • Van Loon J, Weinshilboum, RM (1990) Thiopurine methyltransferase isozymes in human renal tissue. Drug Metab Disp 18: 632-838
    • (1990) Drug Metab Disp , vol.18 , pp. 632-838
    • Van Loon, J.1    Weinshilboum, R.M.2
  • 34
    • 0017880983 scopus 로고
    • Human erythrocyte thiopurine methyltransferase: Radiochemical microassay and biochemical properties
    • Weinshilboum RM, Raymond FA, Pazmino PA (1978) Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties. Clin Chim Acta 85:323-333
    • (1978) Clin Chim Acta , vol.85 , pp. 323-333
    • Weinshilboum, R.M.1    Raymond, F.A.2    Pazmino, P.A.3
  • 35
    • 0018822866 scopus 로고
    • Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
    • Weinshilboum RM, Sladek SL (1980) Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Genet: 32:651-662
    • (1980) Am J Genet , vol.32 , pp. 651-662
    • Weinshilboum, R.M.1    Sladek, S.L.2
  • 36
    • 0020640116 scopus 로고
    • Human kidney thiopurine methyltransferase purification and biochemical properties
    • Woodson L, Weinshilboum RM (1983) Human kidney thiopurine methyltransferase purification and biochemical properties. Biochem Pharmacol 32:819-826
    • (1983) Biochem Pharmacol , vol.32 , pp. 819-826
    • Woodson, L.1    Weinshilboum, R.M.2
  • 37
    • 0019956940 scopus 로고
    • Pharmacogenetics of human thiopurine methyltransferase: Kidney erythrocyte correlation and immunotitration studies
    • Woodson LC, Dunnet JH, Weinshilboum RM (1982) Pharmacogenetics of human thiopurine methyltransferase: Kidney erythrocyte correlation and immunotitration studies. J Pharmacol Exp Ther 222:174-181
    • (1982) J Pharmacol Exp Ther , vol.222 , pp. 174-181
    • Woodson, L.C.1    Dunnet, J.H.2    Weinshilboum, R.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.