Allelotype frequency of the thiopurine methyltransferase (TPMT) gene in Japanese

Pharmacogenetics

Volumn 11, Issue 3, 2001, Pages 275-278

  Kumagai, K ^a   Hiyama, K ^a   Ishioka, S ^a   Sato, H ^a   Yamanishi, Y ^a   McLeod, H L ^a   Konishi, F ^a   Maeda, H ^a   Yamakido, M ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Japanese; Polymorphism; Rheumatic disease; Thiopurine methyltransferase

Indexed keywords

AZATHIOPRINE; MERCAPTOPURINE; THIOPURINE METHYLTRANSFERASE;

ALLELE; ARTICLE; CANCER CHEMOTHERAPY; CAUCASIAN; CONTROLLED STUDY; DNA POLYMORPHISM; GENE FREQUENCY; GENE MUTATION; HOMOZYGOSITY; HUMAN; JAPAN; LEUKOPENIA; MALIGNANT NEOPLASTIC DISEASE; PRIORITY JOURNAL; RACE DIFFERENCE;

ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; DNA PRIMERS; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENETICS, POPULATION; GENOTYPE; HUMANS; JAPAN; METHYLTRANSFERASES; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC;

EID: 0035050911     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200104000-00012     Document Type: Article

References (15)

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5. Polymorphism of the thiopurine S-methyltransferase gene in African-Americans
6. Thiopurine methyltransferase genotype and the toxicity of azathioprine in Japanese
7. Genetic polymorphism of thiopurine Smethyltransferase: Clinical importance and molecular mechanisms
8. Isolation of a human thiopurine S-methyltransferase (TPMT) complementary DNA with a single nucleotide transition A719G (TPMT*3C) and its association with loss of TPMT protein and catalytic activity in humans
9. Thiopurine methyltransferase activity in American white subjects and black subjects
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11. Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms
12. Reduced thiopurine methyltransferase activity and development of side effects of azathioprine treatment in patients with rheumatoid arthritis
13. Methylation pharmacogenetics: Catechol O-methyltransferase. thiopurine methyltransferase, and histamine N-methyltransferase
14. Former poison gas workers and cancer: Incidence and inhibition of tumor formation by treatment with biological response modifier N-CWS
15. Molecular diagnosis of thiopurine Smethyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance