메뉴 건너뛰기




Volumn 20, Issue 5-6, 2009, Pages 517-521

Control of microRNA biogenesis by TGFβ signaling pathway-A novel role of Smads in the nucleus

Author keywords

BMP; Drosha; miRNA; Pre miRNA; Pri miRNA; Processing; Smad; TGF

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; GLYCOGEN SYNTHASE KINASE 3; HISTONE DEACETYLASE; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P53; SMAD PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 70649086975     PISSN: 13596101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cytogfr.2009.10.004     Document Type: Review
Times cited : (68)

References (49)
  • 1
    • 6344281172 scopus 로고    scopus 로고
    • Identification of mammalian microRNA host genes and transcription units
    • Rodriguez A., Griffiths-Jones S., Ashurst J.L., and Bradley A. Identification of mammalian microRNA host genes and transcription units. Genome Res 14 (2004) 1902-1910
    • (2004) Genome Res , vol.14 , pp. 1902-1910
    • Rodriguez, A.1    Griffiths-Jones, S.2    Ashurst, J.L.3    Bradley, A.4
  • 2
    • 9344235449 scopus 로고    scopus 로고
    • Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
    • Cai X., Hagedorn C.H., and Cullen B.R. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 10 (2004) 1957-1966
    • (2004) RNA , vol.10 , pp. 1957-1966
    • Cai, X.1    Hagedorn, C.H.2    Cullen, B.R.3
  • 3
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • Lee Y., Kim M., Han J., Yeom K.H., Lee S., Baek S.H., et al. MicroRNA genes are transcribed by RNA polymerase II. EMBO J 23 (2004) 4051-4060
    • (2004) EMBO J , vol.23 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.H.4    Lee, S.5    Baek, S.H.6
  • 4
    • 34547441263 scopus 로고    scopus 로고
    • Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5′ UTR as in the 3′ UTR
    • Lytle J.R., Yario T.A., and Steitz J.A. Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5′ UTR as in the 3′ UTR. Proc Natl Acad Sci USA 104 (2007) 9667-9672
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 9667-9672
    • Lytle, J.R.1    Yario, T.A.2    Steitz, J.A.3
  • 5
    • 54449097149 scopus 로고    scopus 로고
    • A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence
    • Forman J.J., Legesse-Miller A., and Coller H.A. A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence. Proc Natl Acad Sci USA 105 (2008) 14879-14884
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14879-14884
    • Forman, J.J.1    Legesse-Miller, A.2    Coller, H.A.3
  • 7
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
    • Wightman B., Ha I., and Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75 (1993) 855-862
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 9
    • 0034597777 scopus 로고    scopus 로고
    • Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
    • Pasquinelli A.E., Reinhart B.J., Slack F., Martindale M.Q., Kuroda M.I., Maller B., et al. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 408 (2000) 86-89
    • (2000) Nature , vol.408 , pp. 86-89
    • Pasquinelli, A.E.1    Reinhart, B.J.2    Slack, F.3    Martindale, M.Q.4    Kuroda, M.I.5    Maller, B.6
  • 10
    • 1942494040 scopus 로고    scopus 로고
    • Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
    • Sempere L.F., Freemantle S., Pitha-Rowe I., Moss E., Dmitrovsky E., and Ambros V. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol 5 (2004) R13
    • (2004) Genome Biol , vol.5
    • Sempere, L.F.1    Freemantle, S.2    Pitha-Rowe, I.3    Moss, E.4    Dmitrovsky, E.5    Ambros, V.6
  • 11
    • 38049046644 scopus 로고    scopus 로고
    • Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors
    • Lee E.J., Baek M., Gusev Y., Brackett D.J., Nuovo G.J., and Schmittgen T.D. Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors. RNA 14 (2008) 35-42
    • (2008) RNA , vol.14 , pp. 35-42
    • Lee, E.J.1    Baek, M.2    Gusev, Y.3    Brackett, D.J.4    Nuovo, G.J.5    Schmittgen, T.D.6
  • 13
    • 31344454565 scopus 로고    scopus 로고
    • In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes
    • Kloosterman W.P., Wienholds E., de Bruijn E., Kauppinen S., and Plasterk R.H. In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes. Nat Methods 3 (2006) 27-29
    • (2006) Nat Methods , vol.3 , pp. 27-29
    • Kloosterman, W.P.1    Wienholds, E.2    de Bruijn, E.3    Kauppinen, S.4    Plasterk, R.H.5
  • 14
    • 28944439309 scopus 로고    scopus 로고
    • Animal microRNAs confer robustness to gene expression and have a significant impact on 3′UTR evolution
    • Stark A., Brennecke J., Bushati N., Russell R.B., and Cohen S.M. Animal microRNAs confer robustness to gene expression and have a significant impact on 3′UTR evolution. Cell 123 (2005) 1133-1146
    • (2005) Cell , vol.123 , pp. 1133-1146
    • Stark, A.1    Brennecke, J.2    Bushati, N.3    Russell, R.B.4    Cohen, S.M.5
  • 15
    • 50549095181 scopus 로고    scopus 로고
    • let-7 microRNAs in development, stem cells and cancer
    • Bussing I., Slack F.J., and Grosshans H. let-7 microRNAs in development, stem cells and cancer. Trends Mol Med 14 (2008) 400-409
    • (2008) Trends Mol Med , vol.14 , pp. 400-409
    • Bussing, I.1    Slack, F.J.2    Grosshans, H.3
  • 16
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs-microRNAs with a role in cancer
    • Esquela-Kerscher A., and Slack F.J. Oncomirs-microRNAs with a role in cancer. Nat Rev Cancer 6 (2006) 259-269
    • (2006) Nat Rev Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 18
    • 70349145414 scopus 로고    scopus 로고
    • MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer
    • Olson P., Lu J., Zhang H., Shai A., Chun M.G., Wang Y., et al. MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer. Genes Dev 23 (2009) 2152-2165
    • (2009) Genes Dev , vol.23 , pp. 2152-2165
    • Olson, P.1    Lu, J.2    Zhang, H.3    Shai, A.4    Chun, M.G.5    Wang, Y.6
  • 20
    • 10644234841 scopus 로고    scopus 로고
    • The Drosha-DGCR8 complex in primary microRNA processing
    • Han J.J., Lee Y., Yeom K.H., Kim Y.K., Jin H., and Kim V.N. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev 18 (2004) 3016-3027
    • (2004) Genes Dev , vol.18 , pp. 3016-3027
    • Han, J.J.1    Lee, Y.2    Yeom, K.H.3    Kim, Y.K.4    Jin, H.5    Kim, V.N.6
  • 21
    • 10344248903 scopus 로고    scopus 로고
    • The human DiGeorge syndrome critical region gene 8 and its d-melanogaster homolog are required for miRNA biogenesis
    • Landthaler M., Yalcin A., and Tuschl T. The human DiGeorge syndrome critical region gene 8 and its d-melanogaster homolog are required for miRNA biogenesis. Curr Biol 14 (2004) 2162-2167
    • (2004) Curr Biol , vol.14 , pp. 2162-2167
    • Landthaler, M.1    Yalcin, A.2    Tuschl, T.3
  • 22
    • 33744520104 scopus 로고    scopus 로고
    • Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
    • Han J., Lee Y., Yeom K.H., Nam J.W., Heo I., Rhee J.K., et al. Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125 (2006) 887-901
    • (2006) Cell , vol.125 , pp. 887-901
    • Han, J.1    Lee, Y.2    Yeom, K.H.3    Nam, J.W.4    Heo, I.5    Rhee, J.K.6
  • 25
    • 36048958883 scopus 로고    scopus 로고
    • Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins
    • Shiohama A., Sasaki T., Noda S., Minoshima S., and Shimizu N. Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins. Exp Cell Res 313 (2007) 4196-4207
    • (2007) Exp Cell Res , vol.313 , pp. 4196-4207
    • Shiohama, A.1    Sasaki, T.2    Noda, S.3    Minoshima, S.4    Shimizu, N.5
  • 26
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control DROSHA-mediated microRNA maturation
    • Davis B.N., Hilyard A.C., Lagna G., and Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 454 (2008) 56-61
    • (2008) Nature , vol.454 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3    Hata, A.4
  • 28
    • 36248995245 scopus 로고    scopus 로고
    • Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal
    • Fuentealba L.C., Eivers E., Ikeda A., Hurtado C., Kuroda H., Pera E.M., et al. Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal. Cell 131 (2007) 980-993
    • (2007) Cell , vol.131 , pp. 980-993
    • Fuentealba, L.C.1    Eivers, E.2    Ikeda, A.3    Hurtado, C.4    Kuroda, H.5    Pera, E.M.6
  • 29
    • 0030773834 scopus 로고    scopus 로고
    • Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1
    • Kretzschmar M., Doody J., and Massague J. Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1. Nature 389 (1997) 618-622
    • (1997) Nature , vol.389 , pp. 618-622
    • Kretzschmar, M.1    Doody, J.2    Massague, J.3
  • 31
    • 0029834067 scopus 로고    scopus 로고
    • Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways
    • Lagna G., Hata A., Hemmati-Brivanlou A., and Massague J. Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. Nature 383 (1996) 832-836
    • (1996) Nature , vol.383 , pp. 832-836
    • Lagna, G.1    Hata, A.2    Hemmati-Brivanlou, A.3    Massague, J.4
  • 32
    • 34548842261 scopus 로고    scopus 로고
    • Msk is required for nuclear import of TGF-{beta}/BMP-activated Smads
    • Xu L., Yao X., Chen X., Lu P., Zhang B., and Ip Y.T. Msk is required for nuclear import of TGF-{beta}/BMP-activated Smads. J Cell Biol 178 (2007) 981-994
    • (2007) J Cell Biol , vol.178 , pp. 981-994
    • Xu, L.1    Yao, X.2    Chen, X.3    Lu, P.4    Zhang, B.5    Ip, Y.T.6
  • 33
    • 53049104873 scopus 로고    scopus 로고
    • Preferential utilization of Imp7/8 in nuclear import of Smads
    • Yao X., Chen X., Cottonham C., and Xu L. Preferential utilization of Imp7/8 in nuclear import of Smads. J Biol Chem 283 (2008) 22867-22874
    • (2008) J Biol Chem , vol.283 , pp. 22867-22874
    • Yao, X.1    Chen, X.2    Cottonham, C.3    Xu, L.4
  • 34
    • 48249158259 scopus 로고    scopus 로고
    • The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis
    • Yu B., Bi L., Zheng B., Ji L., Chevalier D., Agarwal M., et al. The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis. Proc Natl Acad Sci USA 105 (2008) 10073-10078
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10073-10078
    • Yu, B.1    Bi, L.2    Zheng, B.3    Ji, L.4    Chevalier, D.5    Agarwal, M.6
  • 35
    • 47949100595 scopus 로고    scopus 로고
    • Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
    • Newman M.A., Thomson J.M., and Hammond S.M. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 14 (2008) 1539-1549
    • (2008) RNA , vol.14 , pp. 1539-1549
    • Newman, M.A.1    Thomson, J.M.2    Hammond, S.M.3
  • 36
    • 52049124806 scopus 로고    scopus 로고
    • Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28
    • Piskounova E., Viswanathan S.R., Janas M., LaPierre R.J., Daley G.Q., Sliz P., et al. Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J Biol Chem 283 (2008) 21310-21314
    • (2008) J Biol Chem , vol.283 , pp. 21310-21314
    • Piskounova, E.1    Viswanathan, S.R.2    Janas, M.3    LaPierre, R.J.4    Daley, G.Q.5    Sliz, P.6
  • 37
    • 52949091534 scopus 로고    scopus 로고
    • The let-7 family of microRNAs
    • Roush S., and Slack F.J. The let-7 family of microRNAs. Trends Cell Biol 18 (2008) 505-516
    • (2008) Trends Cell Biol , vol.18 , pp. 505-516
    • Roush, S.1    Slack, F.J.2
  • 38
    • 33846833594 scopus 로고    scopus 로고
    • Post-transcriptional regulation of the let-7 microRNA during neural cell specification
    • Rybak A., Fuchs H., Smirnova L., Brandt C., Pohl E.E., Nitsch R., et al. Post-transcriptional regulation of the let-7 microRNA during neural cell specification. FASEB J 21 (2007) 415-426
    • (2007) FASEB J , vol.21 , pp. 415-426
    • Rybak, A.1    Fuchs, H.2    Smirnova, L.3    Brandt, C.4    Pohl, E.E.5    Nitsch, R.6
  • 39
    • 48649103982 scopus 로고    scopus 로고
    • A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
    • Rybak A., Fuchs H., Smirnova L., Brandt C., Pohl E.E., Nitsch R., et al. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol 10 (2008) 987-993
    • (2008) Nat Cell Biol , vol.10 , pp. 987-993
    • Rybak, A.1    Fuchs, H.2    Smirnova, L.3    Brandt, C.4    Pohl, E.E.5    Nitsch, R.6
  • 41
    • 65449183132 scopus 로고    scopus 로고
    • Features of mammalian microRNA promoters emerge from polymerase II chromatin immunoprecipitation data
    • Corcoran D.L., Pandit K.V., Gordon B., Bhattacharjee A., Kaminski N., and Benos P.V. Features of mammalian microRNA promoters emerge from polymerase II chromatin immunoprecipitation data. PLoS ONE 4 (2009) e5279
    • (2009) PLoS ONE , vol.4
    • Corcoran, D.L.1    Pandit, K.V.2    Gordon, B.3    Bhattacharjee, A.4    Kaminski, N.5    Benos, P.V.6
  • 42
    • 36849048778 scopus 로고    scopus 로고
    • Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression
    • Diederichs S., and Haber D.A. Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression. Cell 131 (2007) 1097-1108
    • (2007) Cell , vol.131 , pp. 1097-1108
    • Diederichs, S.1    Haber, D.A.2
  • 44
    • 59449097723 scopus 로고    scopus 로고
    • How epigenetics can explain human metastasis: a new role for microRNAs
    • Lujambio A., and Esteller M. How epigenetics can explain human metastasis: a new role for microRNAs. Cell Cycle 8 (2009) 377-382
    • (2009) Cell Cycle , vol.8 , pp. 377-382
    • Lujambio, A.1    Esteller, M.2
  • 46
    • 33847748913 scopus 로고    scopus 로고
    • The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function
    • Brueckner B., Stresemann C., Kuner R., Mund C., Musch T., Meister M., et al. The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function. Cancer Res 67 (2007) 1419-1423
    • (2007) Cancer Res , vol.67 , pp. 1419-1423
    • Brueckner, B.1    Stresemann, C.2    Kuner, R.3    Mund, C.4    Musch, T.5    Meister, M.6
  • 47
    • 57749089758 scopus 로고    scopus 로고
    • Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1
    • Nasser M.W., Datta J., Nuovo G., Kutay H., Motiwala T., Majumder S., et al. Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. J Biol Chem 283 (2008) 33394-33405
    • (2008) J Biol Chem , vol.283 , pp. 33394-33405
    • Nasser, M.W.1    Datta, J.2    Nuovo, G.3    Kutay, H.4    Motiwala, T.5    Majumder, S.6
  • 48
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
    • Saito Y., Liang G., Egger G., Friedman J.M., Chuang J.C., Coetzee G.A., et al. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9 (2006) 435-443
    • (2006) Cancer Cell , vol.9 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3    Friedman, J.M.4    Chuang, J.C.5    Coetzee, G.A.6
  • 49
    • 0034678908 scopus 로고    scopus 로고
    • Transcriptional control by the TGF-beta/Smad signaling system
    • Massague J., and Wotton D. Transcriptional control by the TGF-beta/Smad signaling system. EMBO J 19 (2000) 1745-1754
    • (2000) EMBO J , vol.19 , pp. 1745-1754
    • Massague, J.1    Wotton, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.