메뉴 건너뛰기




Volumn , Issue , 2008, Pages 19-49

Pathophysiology of cholesterol gallstone disease

Author keywords

[No Author keywords available]

Indexed keywords


EID: 70549088415     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-88-470-0763-5_3     Document Type: Chapter
Times cited : (10)

References (165)
  • 2
    • 3042538231 scopus 로고    scopus 로고
    • Genetic analysis of cholesterol gallstone formation: Searching for Lith (gallstone) genes
    • Wang DQH, Afdhal NH (2004) Genetic analysis of cholesterol gallstone formation: searching for Lith (gallstone) genes. Curr Gastroenterol Rep 6:140-150
    • (2004) Curr Gastroenterol Rep , vol.6 , pp. 140-150
    • Wang, D.Q.H.1    Afdhal, N.H.2
  • 3
    • 0032819861 scopus 로고    scopus 로고
    • Prevalence and ethnic differences in gallbladder disease in the United States
    • Everhart JE, Khare M, Hill M et al (1999) Prevalence and ethnic differences in gallbladder disease in the United States. Gastroenterology 117:632-639
    • (1999) Gastroenterology , vol.117 , pp. 632-639
    • Everhart, J.E.1    Khare, M.2    Hill, M.3
  • 4
    • 0036234316 scopus 로고    scopus 로고
    • The burden of selected digestive diseases in the United States
    • Sandler RS, Everhart JE, Donowitz M et al (2002) The burden of selected digestive diseases in the United States. Gastroenterology 122:1500-1511
    • (2002) Gastroenterology , vol.122 , pp. 1500-1511
    • Sandler, R.S.1    Everhart, J.E.2    Donowitz, M.3
  • 5
    • 0027236746 scopus 로고
    • Consensus development conference statement on gallstones and laparoscopic cholecystectomy
    • National Institutes of Health
    • National Institutes of Health (1993) Consensus Development Conference Statement on Gallstones and Laparoscopic Cholecystectomy. Am J Surg 165:390-398
    • (1993) Am J Surg , vol.165 , pp. 390-398
  • 6
    • 0028897291 scopus 로고
    • The natural history of gallstones: The GREPCO experience
    • Attili AF, De Santis A, Capri R et al (1995) The natural history of gallstones: the GREPCO experience. Hepatology 21:656-660
    • (1995) Hepatology , vol.21 , pp. 656-660
    • Attili, A.F.1    De Santis, A.2    Capri, R.3
  • 7
    • 0028814821 scopus 로고
    • Epidemiology of gallstone disease in Italy: Prevalence da ta of the Multicenter Italian Study on Cholelithiasis (M. I. C. O. L.)
    • Attili AF, Carulli N, Roda E et al (1995) Epidemiology of gallstone disease in Italy: prevalence da ta of the Multicenter Italian Study on Cholelithiasis (M. I. C. O. L.). Am J Epidemiol 141:158-165
    • (1995) Am J Epidemiol , vol.141 , pp. 158-165
    • Attili, A.F.1    Carulli, N.2    Roda, E.3
  • 8
    • 12644255694 scopus 로고    scopus 로고
    • Factors associated with gallstone disease in the MICOL experience
    • Attili AF, Capocaccia R, Carulli N et al (1997) Factors associated with gallstone disease in the MICOL experience. Hepatology 26:809-818
    • (1997) Hepatology , vol.26 , pp. 809-818
    • Attili, A.F.1    Capocaccia, R.2    Carulli, N.3
  • 9
    • 0032085706 scopus 로고    scopus 로고
    • Diet and gallstones in Italy: The cross-sectional MICOL results
    • Attili AF, Scafato E, Marchioli R et al (1998) Diet and gallstones in Italy: the cross-sectional MICOL results. Hepatology 27:1492-1498
    • (1998) Hepatology , vol.27 , pp. 1492-1498
    • Attili, A.F.1    Scafato, E.2    Marchioli, R.3
  • 10
    • 0032836924 scopus 로고    scopus 로고
    • Clinical manifestations of gallstone disease: Evidence from the multicenter Italian study on cholelithiasis (MICOL)
    • Festi D, Sottili S, Colecchia A et al (1999) Clinical manifestations of gallstone disease: evidence from the multicenter Italian study on cholelithiasis (MICOL). Hepatology 30:839-846
    • (1999) Hepatology , vol.30 , pp. 839-846
    • Festi, D.1    Sottili, S.2    Colecchia, A.3
  • 11
    • 0025891277 scopus 로고
    • Epidemiology and natural history of gallstone disease
    • Diehl AK (1991) Epidemiology and natural history of gallstone disease. Gastroenterol Clin North Am 20:1-19
    • (1991) Gastroenterol Clin North Am , vol.20 , pp. 1-19
    • Diehl, A.K.1
  • 12
    • 3042702620 scopus 로고    scopus 로고
    • Cholesterol gallstones: A fellow traveler with metabolic syndrome?
    • Grundy SM (2004) Cholesterol gallstones: a fellow traveler with metabolic syndrome? Am J Clin Nutr 80:1-2
    • (2004) Am J Clin Nutr , vol.80 , pp. 1-2
    • Grundy, S.M.1
  • 13
    • 14644429715 scopus 로고    scopus 로고
    • High cholesterol absorption efficiency and rapid biliary secretion of chylomicron remnant cholesterol enhance cholelithogenesis in gallstone-susceptible mice
    • Wang DQH, Zhang L, Wang HH (2005) High cholesterol absorption efficiency and rapid biliary secretion of chylomicron remnant cholesterol enhance cholelithogenesis in gallstone-susceptible mice. Biochim Biophys Acta 1733:90-99
    • (2005) Biochim Biophys Acta , vol.1733 , pp. 90-99
    • Wang, D.Q.H.1    Zhang, L.2    Wang, H.H.3
  • 14
    • 27144518494 scopus 로고    scopus 로고
    • Mechanisms of disease: The genetic epidemiology of gallbladder stones
    • Lammert F, Sauerbruch T (2005) Mechanisms of disease: the genetic epidemiology of gallbladder stones. Nat Clin Pract Gastroenterol Hepatol 2:423-433
    • (2005) Nat Clin Pract Gastroenterol Hepatol , vol.2 , pp. 423-433
    • Lammert, F.1    Sauerbruch, T.2
  • 16
    • 0242690333 scopus 로고    scopus 로고
    • Water handling and aquaporins in bile formation: Recent advances and research trends
    • Portincasa P, Moschetta A, Mazzone A et al (2003) Water handling and aquaporins in bile formation: recent advances and research trends. J Hepatol 39:864-874
    • (2003) J Hepatol , vol.39 , pp. 864-874
    • Portincasa, P.1    Moschetta, A.2    Mazzone, A.3
  • 17
    • 0034823167 scopus 로고    scopus 로고
    • Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL
    • Groen AK, Bloks VW, Bandsma RH et al (2001) Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL. J Clin Invest 108:843-850
    • (2001) J Clin Invest , vol.108 , pp. 843-850
    • Groen, A.K.1    Bloks, V.W.2    Bandsma, R.H.3
  • 18
    • 33751299080 scopus 로고    scopus 로고
    • Gallstone disease. Pathogenesis of gallstones: A genetic perspective
    • Grunhage F, Lammert F (2006) Gallstone disease. Pathogenesis of gallstones: a genetic perspective. Best Pract Res Clin Gastroenterol 20:997-1015
    • (2006) Best Pract Res Clin Gastroenterol , vol.20 , pp. 997-1015
    • Grunhage, F.1    Lammert, F.2
  • 19
    • 17744390348 scopus 로고    scopus 로고
    • Accumulation of dietary cholesterol in cytosterolemia caused by mutations in adjacent ABC transporters
    • Berge KE, Tian H, Graf GA et al (2000) Accumulation of dietary cholesterol in cytosterolemia caused by mutations in adjacent ABC transporters. Science 290:1771-1775
    • (2000) Science , vol.290 , pp. 1771-1775
    • Berge, K.E.1    Tian, H.2    Graf, G.A.3
  • 20
    • 0035158733 scopus 로고    scopus 로고
    • Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption
    • Lee MH, Lu K, Hazard S et al (2001) Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. Nat Genet 27:79-83
    • (2001) Nat Genet , vol.27 , pp. 79-83
    • Lee, M.H.1    Lu, K.2    Hazard, S.3
  • 21
    • 0027363563 scopus 로고
    • Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
    • Smit JJM, Schinkel AH, Oude Elferink RPJ et al (1993) Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease. Cell 75:451-462
    • (1993) Cell , vol.75 , pp. 451-462
    • Smit, J.J.M.1    Schinkel, A.H.2    Oude Elferink, R.P.J.3
  • 22
    • 0032813809 scopus 로고    scopus 로고
    • The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease
    • Bodzioch M, Orso E, Klucken J et al (1999) The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease. Nat Genet 22:347-351
    • (1999) Nat Genet , vol.22 , pp. 347-351
    • Bodzioch, M.1    Orso, E.2    Klucken, J.3
  • 23
    • 0032813660 scopus 로고    scopus 로고
    • Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
    • Rust S, Rosier M, Funke H et al (1999) Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1. Nat Genet 22:352-355
    • (1999) Nat Genet , vol.22 , pp. 352-355
    • Rust, S.1    Rosier, M.2    Funke, H.3
  • 24
    • 0032813808 scopus 로고    scopus 로고
    • Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
    • Brooks-Wilson A, Marcil M, Clee SM et al (1999) Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nat Genet 22:336-345
    • (1999) Nat Genet , vol.22 , pp. 336-345
    • Brooks-Wilson, A.1    Marcil, M.2    Clee, S.M.3
  • 25
    • 0040284751 scopus 로고    scopus 로고
    • Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis
    • de Vree JM, Jacquemin E, Sturm E et al (1998) Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis. Proc Natl Acad Sci USA 95:282-287
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 282-287
    • De Vree, J.M.1    Jacquemin, E.2    Sturm, E.3
  • 26
    • 0029990296 scopus 로고    scopus 로고
    • Defect of multidrug-resistance 3 gene expression in a subtype of progressive familial intrahepatic cholestasis
    • Deleuze JF, Jacquemin E, Dubuisson C et al (1996) Defect of multidrug-resistance 3 gene expression in a subtype of progressive familial intrahepatic cholestasis. Hepatology 23:904-908
    • (1996) Hepatology , vol.23 , pp. 904-908
    • Deleuze, J.F.1    Jacquemin, E.2    Dubuisson, C.3
  • 27
    • 17644443114 scopus 로고    scopus 로고
    • Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: Evidence for a defect in protein trafficking
    • Dixon PH, Weerasekera N, Linton KJ et al (2000) Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking. Hum Mol Genet 9:1209-1217
    • (2000) Hum Mol Genet , vol.9 , pp. 1209-1217
    • Dixon, P.H.1    Weerasekera, N.2    Linton, K.J.3
  • 28
    • 17344366172 scopus 로고    scopus 로고
    • A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis
    • Strautnieks SS, Bull LN, Knisely AS et al (1998) A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis. Nat Genet 20:233-238
    • (1998) Nat Genet , vol.20 , pp. 233-238
    • Strautnieks, S.S.1    Bull, L.N.2    Knisely, A.S.3
  • 29
    • 0035158733 scopus 로고    scopus 로고
    • Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption
    • Lee MH, Lu K, Hazard S et al (2001) Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. Nat Genet 27:79-83
    • (2001) Nat Genet , vol.27 , pp. 79-83
    • Lee, M.H.1    Lu, K.2    Hazard, S.3
  • 30
    • 0348111456 scopus 로고    scopus 로고
    • ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion
    • Graf GA, Yu L, Li WP et al (2003) ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion. J Biol Chem 278:48275-48282
    • (2003) J Biol Chem , vol.278 , pp. 48275-48282
    • Graf, G.A.1    Yu, L.2    Li, W.P.3
  • 31
    • 33748754385 scopus 로고    scopus 로고
    • The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice
    • Kosters A, Kunne C, Looije N et al (2006) The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice. J Lipid Res 47:1959-1966
    • (2006) J Lipid Res , vol.47 , pp. 1959-1966
    • Kosters, A.1    Kunne, C.2    Looije, N.3
  • 32
    • 34247399882 scopus 로고    scopus 로고
    • Quantifying anomalous intestinal sterol uptake, lymphatic transport, and biliary secretion in Abcg8 (-/-) mice
    • Wang HH, Patel SB, Carey MC et al (2007) Quantifying anomalous intestinal sterol uptake, lymphatic transport, and biliary secretion in Abcg8 (-/-) mice. Hepatology 45:998-1006
    • (2007) Hepatology , vol.45 , pp. 998-1006
    • Wang, H.H.1    Patel, S.B.2    Carey, M.C.3
  • 33
    • 0036733630 scopus 로고    scopus 로고
    • Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
    • Yu L, Li-Hawkins J, Hammer RE et al (2002) Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J Clin Invest 110:671-680
    • (2002) J Clin Invest , vol.110 , pp. 671-680
    • Yu, L.1    Li-Hawkins, J.2    Hammer, R.E.3
  • 34
    • 0037058995 scopus 로고    scopus 로고
    • Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion
    • Yu L, Hammer RE, Li-Hawkins J et al (2002) Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion. Proc Natl Acad Sci USA 99:16237-16242
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16237-16242
    • Yu, L.1    Hammer, R.E.2    Li-Hawkins, J.3
  • 35
    • 0032540277 scopus 로고    scopus 로고
    • The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver
    • Gerloff T, Stieger B, Hagenbuch B et al (1998) The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver. J Biol Chem 273:10046-10050
    • (1998) J Biol Chem , vol.273 , pp. 10046-10050
    • Gerloff, T.1    Stieger, B.2    Hagenbuch, B.3
  • 36
    • 0035852720 scopus 로고    scopus 로고
    • Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis
    • Wang R, Salem M, Yousef IM et al (2001) Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis. Proc Natl Acad Sci USA 98:2011-2016
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 2011-2016
    • Wang, R.1    Salem, M.2    Yousef, I.M.3
  • 37
    • 0344586817 scopus 로고    scopus 로고
    • Severe cholestasis induced by cholic acid feeding in knockout mice of sister of P-glycoprotein
    • Wang R, Lam P, Liu L et al (2003) Severe cholestasis induced by cholic acid feeding in knockout mice of sister of P-glycoprotein. Hepatology 38:1489-1499
    • (2003) Hepatology , vol.38 , pp. 1489-1499
    • Wang, R.1    Lam, P.2    Liu, L.3
  • 38
    • 0040284751 scopus 로고    scopus 로고
    • Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis
    • de Vree JM, Jacquemin E, Sturm E et al (1998) Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis. Proc Natl Acad Sci USA 95:282-287
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 282-287
    • De Vree, J.M.1    Jacquemin, E.2    Sturm, E.3
  • 39
    • 0031582195 scopus 로고    scopus 로고
    • Influence of bile salts on molecular interactions between sphingomyelin and cholesterol: Relevance to bile formation and stability
    • van Erpecum KJ, Carey MC (1997) Influence of bile salts on molecular interactions between sphingomyelin and cholesterol: relevance to bile formation and stability. Biochim Biophys Acta 1345:269-282
    • (1997) Biochim Biophys Acta , vol.1345 , pp. 269-282
    • Van Erpecum, K.J.1    Carey, M.C.2
  • 40
    • 0033026760 scopus 로고    scopus 로고
    • Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
    • Wang H, Chen J, Hollister K et al (1999) Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. Mol Cell 3:543-553
    • (1999) Mol Cell , vol.3 , pp. 543-553
    • Wang, H.1    Chen, J.2    Hollister, K.3
  • 41
    • 0033591297 scopus 로고    scopus 로고
    • Identification of a nuclear receptor for bile acids
    • Makishima M, Okamoto AY, Repa JJ et al (1999) Identification of a nuclear receptor for bile acids. Science 284:1362-1365
    • (1999) Science , vol.284 , pp. 1362-1365
    • Makishima, M.1    Okamoto, A.Y.2    Repa, J.J.3
  • 42
    • 0033591387 scopus 로고    scopus 로고
    • Bile acids: Natural ligands for an orphan nuclear receptor
    • Parks DJ, Blanchard SG, Bledsoe RK et al (1999) Bile acids: natural ligands for an orphan nuclear receptor. Science 284:1365-1368
    • (1999) Science , vol.284 , pp. 1365-1368
    • Parks, D.J.1    Blanchard, S.G.2    Bledsoe, R.K.3
  • 43
    • 0029805887 scopus 로고    scopus 로고
    • An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
    • Janowski BA, Willy PJ, Devi TR et al (1996) An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. Nature 383:728-731
    • (1996) Nature , vol.383 , pp. 728-731
    • Janowski, B.A.1    Willy, P.J.2    Devi, T.R.3
  • 44
    • 0035063045 scopus 로고    scopus 로고
    • Key regulatory oxysterols in liver: Analysis as delta4-3-ketone derivatives by HPLC and response to physiological perturbations
    • Zhang Z, Li D, Blanchard DE et al (2001) Key regulatory oxysterols in liver: analysis as delta4-3-ketone derivatives by HPLC and response to physiological perturbations. J Lipid Res 42:649-658
    • (2001) J Lipid Res , vol.42 , pp. 649-658
    • Zhang, Z.1    Li, D.2    Blanchard, D.E.3
  • 45
    • 0035800772 scopus 로고    scopus 로고
    • Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor
    • Ananthanarayanan M, Balasubramanian N, Makishima M et al (2001) Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor. J Biol Chem 276:28857-28865
    • (2001) J Biol Chem , vol.276 , pp. 28857-28865
    • Ananthanarayanan, M.1    Balasubramanian, N.2    Makishima, M.3
  • 46
    • 9144243644 scopus 로고    scopus 로고
    • Farnesoid X-receptor activates transcription of the phospholipid pump MDR3
    • Huang L, Zhao A, Lew JL et al (2003) Farnesoid X-receptor activates transcription of the phospholipid pump MDR3. J Biol Chem 278:51085-51090
    • (2003) J Biol Chem , vol.278 , pp. 51085-51090
    • Huang, L.1    Zhao, A.2    Lew, J.L.3
  • 47
    • 0037166261 scopus 로고    scopus 로고
    • Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta
    • Repa JJ, Berge KE, Pomajzl C et al (2002) Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta. J Biol Chem 277:18793-18800
    • (2002) J Biol Chem , vol.277 , pp. 18793-18800
    • Repa, J.J.1    Berge, K.E.2    Pomajzl, C.3
  • 48
    • 33749344968 scopus 로고    scopus 로고
    • Nuclear bile acid receptor FXR as pharmacological target: Are we there yet?
    • Modica S, Moschetta A (2006) Nuclear bile acid receptor FXR as pharmacological target: are we there yet? FEBS Lett 580:5492-5499
    • (2006) FEBS Lett , vol.580 , pp. 5492-5499
    • Modica, S.1    Moschetta, A.2
  • 49
    • 0031042762 scopus 로고    scopus 로고
    • () Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR
    • Willy PJ, Mangelsdorf DJ () Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR. Genes Dev 11:289-298
    • Genes Dev , vol.11 , pp. 289-298
    • Willy, P.J.1    Mangelsdorf, D.J.2
  • 50
    • 0034666027 scopus 로고    scopus 로고
    • Role of FXR and FTF in bile acid-mediated suppression of cholesterol 7alpha-hydroxylase transcription
    • del Castillo-Olivares A, Gil G (2000) Role of FXR and FTF in bile acid-mediated suppression of cholesterol 7alpha-hydroxylase transcription. Nucl Acids Res 28:3587-3593
    • (2000) Nucl Acids Res , vol.28 , pp. 3587-3593
    • Del Castillo-Olivares, A.1    Gil, G.2
  • 51
    • 0033636789 scopus 로고    scopus 로고
    • Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
    • Lu TT, Makishima M, Repa JJ et al (2000) Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors. Mol Cell 6:507-515
    • (2000) Mol Cell , vol.6 , pp. 507-515
    • Lu, T.T.1    Makishima, M.2    Repa, J.J.3
  • 52
    • 0013199471 scopus 로고    scopus 로고
    • Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
    • Peet DJ, Turley SD, Ma W et al (1998) Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell 93:693-704
    • (1998) Cell , vol.93 , pp. 693-704
    • Peet, D.J.1    Turley, S.D.2    Ma, W.3
  • 53
    • 0017805654 scopus 로고
    • The physical chemistry of cholesterol solubility in bile. Relation to gallstone formation and dissolution in man
    • Carey MC, Small DM (1978) The physical chemistry of cholesterol solubility in bile. Relation to gallstone formation and dissolution in man. J Clin Invest 61:998-1026
    • (1978) J Clin Invest , vol.61 , pp. 998-1026
    • Carey, M.C.1    Small, D.M.2
  • 54
    • 0015631893 scopus 로고
    • Cholesterol solubility in bile. Evidence that supersaturated bile is frequent in healthy man
    • Holzbach RT, Marsh M, Olszewski M et al (1973) Cholesterol solubility in bile. Evidence that supersaturated bile is frequent in healthy man. J Clin Invest 52:1467-1479
    • (1973) J Clin Invest , vol.52 , pp. 1467-1479
    • Holzbach, R.T.1    Marsh, M.2    Olszewski, M.3
  • 55
    • 0018786906 scopus 로고
    • Quasielastic light scattering studies of aqueous biliary lipid systems. Size, shape, and thermodynamics of bile salt micelles
    • Mazer NA, Carey MC, Kwasnick RF et al (1979) Quasielastic light scattering studies of aqueous biliary lipid systems. Size, shape, and thermodynamics of bile salt micelles. Biochemistry 18:3064-3075
    • (1979) Biochemistry , vol.18 , pp. 3064-3075
    • Mazer, N.A.1    Carey, M.C.2    Kwasnick, R.F.3
  • 56
    • 0019328524 scopus 로고
    • Quasielastic light-scattering studies of aqueous biliary lipid systems. Mixed micelle formation in bile salt-lecithin solutions
    • Mazer NA, Benedek GB, Carey MC (1980) Quasielastic light-scattering studies of aqueous biliary lipid systems. Mixed micelle formation in bile salt-lecithin solutions. Biochemistry 19:601-615
    • (1980) Biochemistry , vol.19 , pp. 601-615
    • Mazer, N.A.1    Benedek, G.B.2    Carey, M.C.3
  • 57
    • 0021107167 scopus 로고
    • Quasi-elastic lightscattering studies of aqueous biliary lipid systems. Cholesterol solubilization and precipitation in model bile solutions
    • Mazer NA, Carey MC (1983) Quasi-elastic lightscattering studies of aqueous biliary lipid systems. Cholesterol solubilization and precipitation in model bile solutions. Biochemistry 22:426-442
    • (1983) Biochemistry , vol.22 , pp. 426-442
    • Mazer, N.A.1    Carey, M.C.2
  • 58
    • 0021333225 scopus 로고
    • Quasi-elastic light scattering studies of native hepatic bile from the dog: Comparison with aggregative behavior of model biliary lipid systems
    • Mazer NA, Schurtenberg P, Carey MC et al (1984) Quasi-elastic light scattering studies of native hepatic bile from the dog: comparison with aggregative behavior of model biliary lipid systems. Biochemistry 23:1994-2005
    • (1984) Biochemistry , vol.23 , pp. 1994-2005
    • Mazer, N.A.1    Schurtenberg, P.2    Carey, M.C.3
  • 59
    • 0020954614 scopus 로고
    • A non-micellar mode of cholesterol transport in human bile
    • Somjen GJ, Gilat T (1983) A non-micellar mode of cholesterol transport in human bile. FEBS Lett 156:265-268
    • (1983) FEBS Lett , vol.156 , pp. 265-268
    • Somjen, G.J.1    Gilat, T.2
  • 60
    • 0021851540 scopus 로고
    • Contribution of vesicular and micellar carriers to cholesterol transport in human bile
    • Somjen GJ, Gilat T (1985) Contribution of vesicular and micellar carriers to cholesterol transport in human bile. J Lipid Res 26:699-704
    • (1985) J Lipid Res , vol.26 , pp. 699-704
    • Somjen, G.J.1    Gilat, T.2
  • 61
    • 0022911930 scopus 로고
    • Cholesterol-phospholipid vesicles in human bile: An ultrastructural study
    • Somjen GJ, Marikovsky Y, Lelkes P et al (1986) Cholesterol-phospholipid vesicles in human bile: an ultrastructural study. Biochim Biophys Acta 879:14-21
    • (1986) Biochim Biophys Acta , vol.879 , pp. 14-21
    • Somjen, G.J.1    Marikovsky, Y.2    Lelkes, P.3
  • 62
    • 0022633793 scopus 로고
    • Rapid vesicle formation and aggregation in abnormal human biles: A time-lapse video-enhanced contrast microscopy study
    • Halpern Z, Dudley MA, Kibe A et al (1986) Rapid vesicle formation and aggregation in abnormal human biles: a time-lapse video-enhanced contrast microscopy study. Gastroenterology 90:875-885
    • (1986) Gastroenterology , vol.90 , pp. 875-885
    • Halpern, Z.1    Dudley, M.A.2    Kibe, A.3
  • 63
    • 0022641699 scopus 로고
    • Vesicle aggregation in model systems of supersaturated bile: Relation to crystal nucleation and lipid composition of the vesicular phase
    • Halpern Z, Dudley MA, Lynn MP et al (1986) Vesicle aggregation in model systems of supersaturated bile: relation to crystal nucleation and lipid composition of the vesicular phase. J Lipid Res 27:295-306
    • (1986) J Lipid Res , vol.27 , pp. 295-306
    • Halpern, Z.1    Dudley, M.A.2    Lynn, M.P.3
  • 64
    • 0018699743 scopus 로고
    • Nucleation time: A key factor in the pathogenesis of cholesterol gallstone disease
    • Holan KR, Holzbach RT, Hermann RE et al (1979) Nucleation time: a key factor in the pathogenesis of cholesterol gallstone disease. Gastroenterology 77:611-617
    • (1979) Gastroenterology , vol.77 , pp. 611-617
    • Holan, K.R.1    Holzbach, R.T.2    Hermann, R.E.3
  • 65
    • 0017837440 scopus 로고
    • Liquid crystals and cholesterol nucleation during equilibration in supersaturated bile analogs
    • Holzbach RT, Corbusier C (1978) Liquid crystals and cholesterol nucleation during equilibration in supersaturated bile analogs. Biochim Biophys Acta 528:436-444
    • (1978) Biochim Biophys Acta , vol.528 , pp. 436-444
    • Holzbach, R.T.1    Corbusier, C.2
  • 67
    • 0029958885 scopus 로고    scopus 로고
    • Complete mapping of crystallization pathways during cholesterol precipitation from model bile: Influence of physicalchemical variables of pathophysiologic relevance and identification of a stable liquid crystalline state in cold, dilute and hydrophilic bile salt-containing system
    • Wang DQH, Carey MC (1996) Complete mapping of crystallization pathways during cholesterol precipitation from model bile: influence of physicalchemical variables of pathophysiologic relevance and identification of a stable liquid crystalline state in cold, dilute and hydrophilic bile salt-containing system. J Lipid Res 37:606-630
    • (1996) J Lipid Res , vol.37 , pp. 606-630
    • Wang, D.Q.H.1    Carey, M.C.2
  • 68
    • 0014283788 scopus 로고
    • The physicochemical basis of cholesterol gallstone formation in man
    • Admirand WH, Small DM (1968) The physicochemical basis of cholesterol gallstone formation in man. J Clin Invest 47:1043-1052
    • (1968) J Clin Invest , vol.47 , pp. 1043-1052
    • Admirand, W.H.1    Small, D.M.2
  • 69
    • 0030454457 scopus 로고    scopus 로고
    • Characterization of crystallization pathways during cholesterol precipitation from human gallbladder biles: Identical pathways to corresponding model biles with three predominating sequences
    • Wang DQH, Carey MC (1996) Characterization of crystallization pathways during cholesterol precipitation from human gallbladder biles: identical pathways to corresponding model biles with three predominating sequences. J Lipid Res 37:2539-2549
    • (1996) J Lipid Res , vol.37 , pp. 2539-2549
    • Wang, D.Q.H.1    Carey, M.C.2
  • 70
    • 0014023261 scopus 로고
    • Terna - Ry and quaternary aqueous systems containing bile salt, lecithin, and cholesterol
    • Small DM, Bourges M, Dervichian DG (1966) Terna - ry and quaternary aqueous systems containing bile salt, lecithin, and cholesterol. Nature 211:816-818
    • (1966) Nature , vol.211 , pp. 816-818
    • Small, D.M.1    Bourges, M.2    Dervichian, D.G.3
  • 71
    • 0014008391 scopus 로고
    • The biophysics of lipidic associations. I. The ternary systems: Lecithin-bile salt-water
    • Small DM, Bourges MC, Dervichian DG (1966) The biophysics of lipidic associations. I. The ternary systems: lecithin-bile salt-water. Biochim Biophys Acta 125:563-580
    • (1966) Biochim Biophys Acta , vol.125 , pp. 563-580
    • Small, D.M.1    Bourges, M.C.2    Dervichian, D.G.3
  • 72
    • 0014266665 scopus 로고
    • A classification of biologic lipids based upon their interaction in aqueous systems
    • Small DM (1968) A classification of biologic lipids based upon their interaction in aqueous systems. J Am Oil Chem Soc 45:108-119
    • (1968) J Am Oil Chem Soc , vol.45 , pp. 108-119
    • Small, D.M.1
  • 73
    • 0014682757 scopus 로고
    • Solubility of bile salts
    • Small DM, Admirand W (1969) Solubility of bile salts. Nature 221:265-267
    • (1969) Nature , vol.221 , pp. 265-267
    • Small, D.M.1    Admirand, W.2
  • 75
    • 0027017761 scopus 로고
    • Cholesterol gallstone formation. 2. Pathobiology and pathomechanics
    • La Mont JT, Carey MC (1992) Cholesterol gallstone formation. 2. Pathobiology and pathomechanics. Prog Liver Dis 10:165-191
    • (1992) Prog Liver Dis , vol.10 , pp. 165-191
    • La Mont, J.T.1    Carey, M.C.2
  • 76
    • 0032969399 scopus 로고    scopus 로고
    • No pathophysiologic relationship of soluble biliary proteins to cholesterol crystallization in human bile
    • Wang DQH, Cohen DE, Lammert F et al (1999) No pathophysiologic relationship of soluble biliary proteins to cholesterol crystallization in human bile. J Lipid Res 40:415-425
    • (1999) J Lipid Res , vol.40 , pp. 415-425
    • Wang, D.Q.H.1    Cohen, D.E.2    Lammert, F.3
  • 77
    • 0018092980 scopus 로고
    • Critical tables for calculating the cholesterol saturation of native bile
    • Carey MC (1978) Critical tables for calculating the cholesterol saturation of native bile. J Lipid Res 19:945-955
    • (1978) J Lipid Res , vol.19 , pp. 945-955
    • Carey, M.C.1
  • 78
    • 0020559783 scopus 로고
    • Nucleation of cholesterol monohydrate crystals from hepatic and gallbladder bile of patients with cholesterol gallstones
    • Gollish SH, Burnstein MJ, Ilson RG et al (1983) Nucleation of cholesterol monohydrate crystals from hepatic and gallbladder bile of patients with cholesterol gallstones. Gut 24:836-844
    • (1983) Gut , vol.24 , pp. 836-844
    • Gollish, S.H.1    Burnstein, M.J.2    Ilson, R.G.3
  • 79
    • 0023633064 scopus 로고
    • Nucleation of cholesterol from vesicles isolated from bile of patients with and without cholesterol gallstones
    • Harvey PRC, Sömjen G, Lichtenberg MS et al (1987) Nucleation of cholesterol from vesicles isolated from bile of patients with and without cholesterol gallstones. Biochim Biophys Acta 921:198-204
    • (1987) Biochim Biophys Acta , vol.921 , pp. 198-204
    • Harvey, P.R.C.1    Sömjen, G.2    Lichtenberg, M.S.3
  • 80
    • 0025156059 scopus 로고
    • Current concepts of cholesterol transport and crystal formation in human bile
    • Holzbach RT (1990) Current concepts of cholesterol transport and crystal formation in human bile. Hepatology 12:26S-31S
    • (1990) Hepatology , vol.12
    • Holzbach, R.T.1
  • 81
    • 0025172165 scopus 로고
    • Nucleation of cholesterol crystals in native bile
    • Holzbach RT (1990) Nucleation of cholesterol crystals in native bile. Hepatology 12:155S-161S
    • (1990) Hepatology , vol.12
    • Holzbach, R.T.1
  • 82
    • 0030810683 scopus 로고    scopus 로고
    • Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: Physical-chemistry of gallbladder bile
    • Wang DQH, Paigen B, Carey MC (1997) Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: physical-chemistry of gallbladder bile. J Lipid Res 38:1395-1411
    • (1997) J Lipid Res , vol.38 , pp. 1395-1411
    • Wang, D.Q.H.1    Paigen, B.2    Carey, M.C.3
  • 83
    • 33745877343 scopus 로고    scopus 로고
    • Evidence that gallbladder epithelial mucin enhances cholesterol cholelithogenesis in MUC1 transgenic mice
    • Wang HH, Afdhal NH, Gendler SJ et al (2006) Evidence that gallbladder epithelial mucin enhances cholesterol cholelithogenesis in MUC1 transgenic mice. Gastroenterology 131:210-222
    • (2006) Gastroenterology , vol.131 , pp. 210-222
    • Wang, H.H.1    Afdhal, N.H.2    Gendler, S.J.3
  • 84
    • 0026630605 scopus 로고
    • Filamentous, helical and tubular microstructures during cholesterol crystallization from bile. Evidence that biliary cholesterol does not nucleate classic monohydrate plates
    • Konikoff FM, Chung DS, Donovan JM et al (1992) Filamentous, helical and tubular microstructures during cholesterol crystallization from bile. Evidence that biliary cholesterol does not nucleate classic monohydrate plates. J Clin Invest 90:1156-1161
    • (1992) J Clin Invest , vol.90 , pp. 1156-1161
    • Konikoff, F.M.1    Chung, D.S.2    Donovan, J.M.3
  • 85
    • 0028013594 scopus 로고
    • Phospholipid molecular species influence crystal habits and transition sequences of metastable intermediates during cholesterol crystallization from bile salt-rich model bile
    • Konikoff FM, Cohen DE, Carey MC (1994) Phospholipid molecular species influence crystal habits and transition sequences of metastable intermediates during cholesterol crystallization from bile salt-rich model bile. J Lipid Res 35:60-70
    • (1994) J Lipid Res , vol.35 , pp. 60-70
    • Konikoff, F.M.1    Cohen, D.E.2    Carey, M.C.3
  • 86
    • 0031041563 scopus 로고    scopus 로고
    • Monitoring cholesterol crystallization from lithogenic model bile by time-lapse density gradient ultracentrifugation
    • Konikoff FM, Laufer H, Messer G et al (1997) Monitoring cholesterol crystallization from lithogenic model bile by time-lapse density gradient ultracentrifugation. J Hepatol 26:703-710
    • (1997) J Hepatol , vol.26 , pp. 703-710
    • Konikoff, F.M.1    Laufer, H.2    Messer, G.3
  • 87
    • 1442355466 scopus 로고    scopus 로고
    • Spontaneous cholecysto-and hepatolithiasis in Mdr2-/-mice: A model for low phospholipid-associated cholelithiasis
    • Lammert F, Wang DQH, Hillebrandt S et al (2004) Spontaneous cholecysto-and hepatolithiasis in Mdr2-/-mice: a model for low phospholipid-associated cholelithiasis. Hepatology 39:117-128
    • (2004) Hepatology , vol.39 , pp. 117-128
    • Lammert, F.1    Wang, D.Q.H.2    Hillebrandt, S.3
  • 89
    • 0030943479 scopus 로고    scopus 로고
    • Newer pathogenetic concepts in cholesterol gallstone formation: A unitary hypothesis
    • Holzbach RT (1997) Newer pathogenetic concepts in cholesterol gallstone formation: a unitary hypothesis. Digestion 58 Suppl 1:29-32
    • (1997) Digestion , vol.58 , Issue.SUPPL. 1 , pp. 29-32
    • Holzbach, R.T.1
  • 90
    • 0025906437 scopus 로고
    • Inhibition and promotion of cholesterol crystallization by protein factors from normal human gallbladder bile
    • Busch N, Matiuck N, Sahlin S et al (1991) Inhibition and promotion of cholesterol crystallization by protein factors from normal human gallbladder bile. J Lipid Res 32:695-702
    • (1991) J Lipid Res , vol.32 , pp. 695-702
    • Busch, N.1    Matiuck, N.2    Sahlin, S.3
  • 91
    • 0019419074 scopus 로고
    • Role of gallbladder mucus hypersecretion in the evolution of cholesterol gallstones. Studies in the prairie dog
    • Lee SM, La Mont JT, Carey MC (1981) Role of gallbladder mucus hypersecretion in the evolution of cholesterol gallstones. Studies in the prairie dog. J Clin Invest 67:1712-1723
    • (1981) J Clin Invest , vol.67 , pp. 1712-1723
    • Lee, S.M.1    La Mont, J.T.2    Carey, M.C.3
  • 92
    • 0027479111 scopus 로고
    • Cholesterol cholelithiasis in the prairie dog: Role of mucin and nonmucin glycoproteins
    • Afdhal NH, Gong D, Niu N et al (1993) Cholesterol cholelithiasis in the prairie dog: role of mucin and nonmucin glycoproteins. Hepatology 17:693-700
    • (1993) Hepatology , vol.17 , pp. 693-700
    • Afdhal, N.H.1    Gong, D.2    Niu, N.3
  • 93
    • 0020017547 scopus 로고
    • Gallbladder mucin glycoprotein hypersecretion in experimental cholelithiasis: Role of mucin gel in nucleation of cholesterol gallstones
    • La Mont JT (1982) Gallbladder mucin glycoprotein hypersecretion in experimental cholelithiasis: role of mucin gel in nucleation of cholesterol gallstones. Adv Exp Med Biol 144:231-234
    • (1982) Adv Exp Med Biol , vol.144 , pp. 231-234
    • La Mont, J.T.1
  • 94
    • 0021240377 scopus 로고
    • Human gallbladder mucin accelerates nucleation of cholesterol in artificial bile
    • Levy PF, Smith BF, La Mont JT (1984) Human gallbladder mucin accelerates nucleation of cholesterol in artificial bile. Gastroenterology 87:270-275
    • (1984) Gastroenterology , vol.87 , pp. 270-275
    • Levy, P.F.1    Smith, B.F.2    La Mont, J.T.3
  • 95
    • 0022639045 scopus 로고
    • Nature and composition of biliary sludge
    • Lee SP, Nicholls JF (1986) Nature and composition of biliary sludge. Gastroenterology 90:677-686
    • (1986) Gastroenterology , vol.90 , pp. 677-686
    • Lee, S.P.1    Nicholls, J.F.2
  • 98
    • 1542723749 scopus 로고    scopus 로고
    • Targeted disruption of the murine mucin gene 1 decreases susceptibility to cholesterol gallstone formation
    • Wang HH, Afdhal NH, Gendler SJ et al (2004) Targeted disruption of the murine mucin gene 1 decreases susceptibility to cholesterol gallstone formation. J Lipid Res 45:438-447
    • (2004) J Lipid Res , vol.45 , pp. 438-447
    • Wang, H.H.1    Afdhal, N.H.2    Gendler, S.J.3
  • 99
    • 0346109626 scopus 로고    scopus 로고
    • Interacting QTLs for cholesterol gallstones and gallbladder mucin in AKR and SWR strains of mice
    • Wittenburg H, Lammert F, Wang DQH et al (2002) Interacting QTLs for cholesterol gallstones and gallbladder mucin in AKR and SWR strains of mice. Physiol Genomics 8:67-77
    • (2002) Physiol Genomics , vol.8 , pp. 67-77
    • Wittenburg, H.1    Lammert, F.2    Wang, D.Q.H.3
  • 100
    • 0025343809 scopus 로고
    • Isolation of a potent cholesterol nucleation-promoting activity from human gallbladder bile of patients with solitary or multiple cholesterol gallstones
    • Groen AK, Noordam C, Drapers JAG et al (1990) Isolation of a potent cholesterol nucleation-promoting activity from human gallbladder bile of patients with solitary or multiple cholesterol gallstones. Hepatology 11:525-533
    • (1990) Hepatology , vol.11 , pp. 525-533
    • Groen, A.K.1    Noordam, C.2    Drapers, J.A.G.3
  • 101
    • 0028793304 scopus 로고
    • Deoxycholic acid influences cholesterol solubilization and microcrystal nucleation time in gallbladder bile
    • Hussaini SH, Pereira SP, Murphy GM et al (1995) Deoxycholic acid influences cholesterol solubilization and microcrystal nucleation time in gallbladder bile. Hepatology 22:1735-1744
    • (1995) Hepatology , vol.22 , pp. 1735-1744
    • Hussaini, S.H.1    Pereira, S.P.2    Murphy, G.M.3
  • 102
    • 0031978505 scopus 로고    scopus 로고
    • Cholesterol saturation, not proteins or cholecystitis, is critical for crystal formation in human gallbladder bile
    • Miquel JF, Nunez L, Amigo L et al (1998) Cholesterol saturation, not proteins or cholecystitis, is critical for crystal formation in human gallbladder bile. Gastroenterology 114:1016-1023
    • (1998) Gastroenterology , vol.114 , pp. 1016-1023
    • Miquel, J.F.1    Nunez, L.2    Amigo, L.3
  • 103
    • 0021351853 scopus 로고
    • Biliary proteins: Unique inhibitors of cholesterol crystal nucleation in human gallbladder bile
    • Holzbach RT, Kibe A, Thiel E et al (1984) Biliary proteins: unique inhibitors of cholesterol crystal nucleation in human gallbladder bile. J Clin Invest 73:35-45
    • (1984) J Clin Invest , vol.73 , pp. 35-45
    • Holzbach, R.T.1    Kibe, A.2    Thiel, E.3
  • 104
    • 0021134732 scopus 로고
    • Inhibition of cholesterol crystal formation by apolipoproteins in supersaturated model bile
    • Kibe A, Holzbach RT (1984) Inhibition of cholesterol crystal formation by apolipoproteins in supersaturated model bile. Science 255:514-516
    • (1984) Science , vol.255 , pp. 514-516
    • Kibe, A.1    Holzbach, R.T.2
  • 105
    • 0033028356 scopus 로고    scopus 로고
    • Apolipoprotein A-I in bile inhibits cholesterol crystallization and modifies transcellular lipid transfer through cultured human gall-bladder epithelial cells
    • Secknus R, Darby GH, Chernosky A et al (1999) Apolipoprotein A-I in bile inhibits cholesterol crystallization and modifies transcellular lipid transfer through cultured human gall-bladder epithelial cells. J Gastroenterol Hepatol 14:446-456
    • (1999) J Gastroenterol Hepatol , vol.14 , pp. 446-456
    • Secknus, R.1    Darby, G.H.2    Chernosky, A.3
  • 106
    • 0028305832 scopus 로고
    • The effect of bile acid hydrophobicity on nucleation of several types of cholesterol crystals from model bile vesicles
    • Stolk MFJ, van de Heijning BJM, van Erpecum KJ et al (1994) The effect of bile acid hydrophobicity on nucleation of several types of cholesterol crystals from model bile vesicles. J Hepatol 20:802-810
    • (1994) J Hepatol , vol.20 , pp. 802-810
    • Stolk, M.F.J.1    Van De Heijning, B.J.M.2    Van Erpecum, K.J.3
  • 108
    • 0027943072 scopus 로고
    • Effects of bile salt and phospholipid hydrophobicity on lithogenicity of human gallbladder bile
    • van Erpecum KJ, Portincasa P, Stolk MFJ et al (1994) Effects of bile salt and phospholipid hydrophobicity on lithogenicity of human gallbladder bile. Eur J Clin Invest 24:744-750
    • (1994) Eur J Clin Invest , vol.24 , pp. 744-750
    • Van Erpecum, K.J.1    Portincasa, P.2    Stolk, M.F.J.3
  • 110
    • 0028169872 scopus 로고
    • Gallbladder motor function in gallstone patients: Sonographic and in vitro studies on the role of gallstones, smooth muscle function and gallbladder wall inflammation
    • Portincasa P, Di Ciaula A, Baldassarre G et al (1994) Gallbladder motor function in gallstone patients: sonographic and in vitro studies on the role of gallstones, smooth muscle function and gallbladder wall inflammation. J Hepatol 21:430-440
    • (1994) J Hepatol , vol.21 , pp. 430-440
    • Portincasa, P.1    Di Ciaula, A.2    Baldassarre, G.3
  • 111
    • 0035122649 scopus 로고    scopus 로고
    • Severe impairment of postprandial cholecystokinin release and gall-bladder emptying and high risk of gallstone formation in acromegalic patients during Sandostatin LAR
    • Moschetta A, Stolk MF, Rehfeld JF et al (2001) Severe impairment of postprandial cholecystokinin release and gall-bladder emptying and high risk of gallstone formation in acromegalic patients during Sandostatin LAR. Aliment Pharmacol Ther 15:181-185
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 181-185
    • Moschetta, A.1    Stolk, M.F.2    Rehfeld, J.F.3
  • 112
    • 85047693084 scopus 로고    scopus 로고
    • Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis
    • Wang DQH, Schmitz F, Kopin AS et al (2004) Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis. J Clin Invest 114:521-528
    • (2004) J Clin Invest , vol.114 , pp. 521-528
    • Wang, D.Q.H.1    Schmitz, F.2    Kopin, A.S.3
  • 113
    • 0025157104 scopus 로고
    • Cholecystokinin prevents parenteral nutrition induced biliary sludge in humans
    • Sitzmann JV, Pitt HA, Steinborn PA et al (1990) Cholecystokinin prevents parenteral nutrition induced biliary sludge in humans. Surg Gynecol Obstet 170:25-31
    • (1990) Surg Gynecol Obstet , vol.170 , pp. 25-31
    • Sitzmann, J.V.1    Pitt, H.A.2    Steinborn, P.A.3
  • 114
    • 0029795454 scopus 로고    scopus 로고
    • The role of gallbladder emptying in gallstone formation during diet-induced rapid weight loss
    • Gebhard RL, Prigge WF, Ansel HJ et al (1996) The role of gallbladder emptying in gallstone formation during diet-induced rapid weight loss. Hepatology 24:544-548
    • (1996) Hepatology , vol.24 , pp. 544-548
    • Gebhard, R.L.1    Prigge, W.F.2    Ansel, H.J.3
  • 115
    • 33750515266 scopus 로고    scopus 로고
    • Is it possible to predict the clinical course of gallstone disease? Usefulness of gallbladder motility evaluation in a clinical setting
    • Colecchia A, Sandri L, Bacchi-Reggiani ML et al (2006) Is it possible to predict the clinical course of gallstone disease? Usefulness of gallbladder motility evaluation in a clinical setting. Am J Gastroenterol 101:2576-2581
    • (2006) Am J Gastroenterol , vol.101 , pp. 2576-2581
    • Colecchia, A.1    Sandri, L.2    Bacchi-Reggiani, M.L.3
  • 116
    • 0142244374 scopus 로고    scopus 로고
    • Pan-enteric dysmotility, impaired quality of life and alexithymia in a large group of patients meeting the Rome II criteria for irritable bowel
    • Portincasa P, Moschetta A, Baldassarre G et al (2003) Pan-enteric dysmotility, impaired quality of life and alexithymia in a large group of patients meeting the Rome II criteria for irritable bowel. World J Gastroenterol 9:2293-2299
    • (2003) World J Gastroenterol , vol.9 , pp. 2293-2299
    • Portincasa, P.1    Moschetta, A.2    Baldassarre, G.3
  • 117
    • 4344607728 scopus 로고    scopus 로고
    • Impaired gallbladder motility and delayed orocecal transit contribute to pigment gallstone and biliary sludge formation in beta-thalassemia major adults
    • Portincasa P, Moschetta A, Berardino M et al (2004) Impaired gallbladder motility and delayed orocecal transit contribute to pigment gallstone and biliary sludge formation in beta-thalassemia major adults. World J Gastroenterol 10:2383-2390
    • (2004) World J Gastroenterol , vol.10 , pp. 2383-2390
    • Portincasa, P.1    Moschetta, A.2    Berardino, M.3
  • 120
    • 0028359182 scopus 로고
    • Enhancement of gallbladder emptying in gallstone patients after oral cholestyramine
    • Portincasa P, Di Ciaula A, Palmieri VO et al (1994) Enhancement of gallbladder emptying in gallstone patients after oral cholestyramine. Am J Gastroenterol 89:909-914
    • (1994) Am J Gastroenterol , vol.89 , pp. 909-914
    • Portincasa, P.1    Di Ciaula, A.2    Palmieri, V.O.3
  • 121
    • 0028871884 scopus 로고
    • Effects of cholestyramine on gallbladder and gastric emptying in obese and lean subjects
    • Portincasa P, Di Ciaula A, Palmieri VO et al (1995) Effects of cholestyramine on gallbladder and gastric emptying in obese and lean subjects. Eur J Clin Invest 25:746-753
    • (1995) Eur J Clin Invest , vol.25 , pp. 746-753
    • Portincasa, P.1    Di Ciaula, A.2    Palmieri, V.O.3
  • 122
    • 0029816911 scopus 로고    scopus 로고
    • Apolipoprotein (Apo) E4 genotype and gallbladder motility influence speed of gallstone clearance and risk of recurrence after ex-tracorporeal shock-wave lithotripsy
    • Portincasa P, van Erpecum KJ, van de Meeberg PC et al (1996) Apolipoprotein (Apo) E4 genotype and gallbladder motility influence speed of gallstone clearance and risk of recurrence after ex-tracorporeal shock-wave lithotripsy. Hepatology 24:580-587
    • (1996) Hepatology , vol.24 , pp. 580-587
    • Portincasa, P.1    Van Erpecum, K.J.2    Van De Meeberg, P.C.3
  • 123
    • 0029895567 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid, ursodeoxycholic acid and gallbladder motility in gallstone patients and healthy subjects
    • Portincasa P, Di Ciaula A, Palmieri VO et al (1996) Tauroursodeoxycholic acid, ursodeoxycholic acid and gallbladder motility in gallstone patients and healthy subjects. Ital J Gastroenterol Hepatol 28:111-113
    • (1996) Ital J Gastroenterol Hepatol , vol.28 , pp. 111-113
    • Portincasa, P.1    Di Ciaula, A.2    Palmieri, V.O.3
  • 124
    • 0030820113 scopus 로고    scopus 로고
    • Impaired gallbladder and gastric motility and pathological gastro-esophageal reflux in gallstone patients
    • Portincasa P, Di Ciaula A, Palmieri VO et al (1997) Impaired gallbladder and gastric motility and pathological gastro-esophageal reflux in gallstone patients. Eur J Clin Invest 8:653-661
    • (1997) Eur J Clin Invest , vol.8 , pp. 653-661
    • Portincasa, P.1    Di Ciaula, A.2    Palmieri, V.O.3
  • 125
    • 0033634853 scopus 로고    scopus 로고
    • The effect of acute oral erythromycin on gallbladder motility and on upper gastrointestinal symptoms in gastrectomized patients with and without gallstones: A randomized, placebocontrolled ultrasonographic study
    • Portincasa P, Altomare DF, Moschetta A et al (2000) The effect of acute oral erythromycin on gallbladder motility and on upper gastrointestinal symptoms in gastrectomized patients with and without gallstones: a randomized, placebocontrolled ultrasonographic study. Am J Gastroenterol 95:3444-3451
    • (2000) Am J Gastroenterol , vol.95 , pp. 3444-3451
    • Portincasa, P.1    Altomare, D.F.2    Moschetta, A.3
  • 126
    • 0034050333 scopus 로고    scopus 로고
    • Gallbladder motility and cholesterol crystallization in bile from patients with pigment and cholesterol gallstones
    • Portincasa P, Di Ciaula A, Vendemiale G et al (2000) Gallbladder motility and cholesterol crystallization in bile from patients with pigment and cholesterol gallstones. Eur J Clin Invest 30:317-324
    • (2000) Eur J Clin Invest , vol.30 , pp. 317-324
    • Portincasa, P.1    Di Ciaula, A.2    Vendemiale, G.3
  • 127
    • 0034106865 scopus 로고    scopus 로고
    • Standards for diagnosis of gastrointestinal motility disorders. Section: Ultrasonography. A position statement from the Gruppo Italiano di Studio Motilita Apparato Digerente
    • Portincasa P, Colecchia A, Di Ciaula A et al (2000) Standards for diagnosis of gastrointestinal motility disorders. Section: ultrasonography. A position statement from the Gruppo Italiano di Studio Motilita Apparato Digerente. Dig Liver Dis 32:160-172
    • (2000) Dig Liver Dis , vol.32 , pp. 160-172
    • Portincasa, P.1    Colecchia, A.2    Di Ciaula, A.3
  • 128
    • 0034934895 scopus 로고    scopus 로고
    • Changes of gallbladder and gastric dynamics in patients with acute hepatitis A
    • Portincasa P, Moschetta A, Di Ciaula A et al (2001) Changes of gallbladder and gastric dynamics in patients with acute hepatitis A. Eur J Clin Invest 31:617-622
    • (2001) Eur J Clin Invest , vol.31 , pp. 617-622
    • Portincasa, P.1    Moschetta, A.2    Di Ciaula, A.3
  • 129
    • 0029059211 scopus 로고
    • Gallbladder emptying in vivo, bile composition and nucleation of cholesterol crystals in patients with cholesterol gallstones
    • Stolk MFJ, van Erpecum KJ, Renooij W et al (1995) Gallbladder emptying in vivo, bile composition and nucleation of cholesterol crystals in patients with cholesterol gallstones. Gastroenterology 108:1882-1888
    • (1995) Gastroenterology , vol.108 , pp. 1882-1888
    • Stolk, M.F.J.1    Van Erpecum, K.J.2    Renooij, W.3
  • 130
    • 0026581555 scopus 로고
    • Fasting gallbladder volume, postprandial emptying and cholecystokinin release in gallstone patients and normal subjects
    • van Erpecum KJ, van Berge-Henegouwen GP, Stolk MFJ et al (1992) Fasting gallbladder volume, postprandial emptying and cholecystokinin release in gallstone patients and normal subjects. J Hepatol 14:194-202
    • (1992) J Hepatol , vol.14 , pp. 194-202
    • Van Erpecum, K.J.1    Van Berge-Henegouwen, G.P.2    Stolk, M.F.J.3
  • 131
    • 13844306706 scopus 로고    scopus 로고
    • Impaired cytoprotective function of muscle in human gallbladders with cholesterol stones
    • Xiao ZL, Amaral J, Biancani P et al (2005) Impaired cytoprotective function of muscle in human gallbladders with cholesterol stones. Am. J Physiol Gastrointest Liver Physiol 288:G525-G532
    • (2005) Am. J Physiol Gastrointest Liver Physiol , vol.288
    • Xiao, Z.L.1    Amaral, J.2    Biancani, P.3
  • 132
    • 0018694052 scopus 로고
    • (Relationships among canine fasting pancreatic and biliary secretions, pancreatic duct pressure, and duodenal phase III motor activity - Boldireff revisited
    • Di Magno EP, Hendricks JC, Go VLW et al (1979) (Relationships among canine fasting pancreatic and biliary secretions, pancreatic duct pressure, and duodenal phase III motor activity - Boldireff revisited. Dig Dis Sci 24:689-693
    • (1979) Dig Dis Sci , vol.24 , pp. 689-693
    • Di Magno, E.P.1    Hendricks, J.C.2    Go, V.L.W.3
  • 133
    • 0027152112 scopus 로고
    • Motor cycles with phase III in antrum are associated with high motilin levels and prolonged gallbladder emptying
    • Stolk MFJ, van Erpecum KJ, Smout AJPM et al (1993) Motor cycles with phase III in antrum are associated with high motilin levels and prolonged gallbladder emptying. Am J Physiol 264:G596-G600
    • (1993) Am J Physiol , vol.264
    • Stolk, M.F.J.1    Van Erpecum, K.J.2    Smout, A.J.P.M.3
  • 134
    • 0035014304 scopus 로고    scopus 로고
    • Interdigestive gallbladder emptying, antroduodenal motility, and motilin release patterns are altered in cholesterol gallstone patients
    • Stolk MF, van Erpecum KJ, Peeters TL et al (2001) Interdigestive gallbladder emptying, antroduodenal motility, and motilin release patterns are altered in cholesterol gallstone patients. Dig Dis Sci 46:1328-1334
    • (2001) Dig Dis Sci , vol.46 , pp. 1328-1334
    • Stolk, M.F.1    Van Erpecum, K.J.2    Peeters, T.L.3
  • 135
    • 0034085150 scopus 로고    scopus 로고
    • Agents affecting gall-bladder motility-role in treatment and prevention of gallstones (review)
    • van Erpecum KJ, Venneman NG, Portincasa P et al (2000) Agents affecting gall-bladder motility-role in treatment and prevention of gallstones (review). Aliment Pharmacol Ther 14 Suppl 2:66-70
    • (2000) Aliment Pharmacol Ther , vol.14 , Issue.SUPPL. 2 , pp. 66-70
    • Van Erpecum, K.J.1    Venneman, N.G.2    Portincasa, P.3
  • 136
    • 0029789098 scopus 로고    scopus 로고
    • Gallbladder emptying and gallstone formation: A prospective study on gallstone recurrence
    • Pauletzki JG, Althaus R, Holl J et al (1996) Gallbladder emptying and gallstone formation: a prospective study on gallstone recurrence. Gastroenterology 111:765-771
    • (1996) Gastroenterology , vol.111 , pp. 765-771
    • Pauletzki, J.G.1    Althaus, R.2    Holl, J.3
  • 137
    • 0029738276 scopus 로고    scopus 로고
    • Membrane cholesterol alters gallbladder muscle contractility in prairie dogs
    • Yu P, Chen Q, Biancani P et al (1996) Membrane cholesterol alters gallbladder muscle contractility in prairie dogs. Am J Physiol 271:G56-61
    • (1996) Am J Physiol , vol.271
    • Yu, P.1    Chen, Q.2    Biancani, P.3
  • 138
    • 0032996629 scopus 로고    scopus 로고
    • CCK receptor dysfunction in muscle membranes from human gallbladders with cholesterol stones
    • Xiao ZL, Chen Q, Amaral J et al (1999) CCK receptor dysfunction in muscle membranes from human gallbladders with cholesterol stones. Am J Physiol 276:G1401-G1407
    • (1999) Am J Physiol , vol.276
    • Xiao, Z.L.1    Chen, Q.2    Amaral, J.3
  • 139
    • 0028009396 scopus 로고
    • Cholecystokinincoupled intracellular signaling in human gallbladder muscle
    • Yu P, De Petris G, Biancani P et al (1994) Cholecystokinincoupled intracellular signaling in human gallbladder muscle. Gastroenterology 106:763-770
    • (1994) Gastroenterology , vol.106 , pp. 763-770
    • Yu, P.1    De Petris, G.2    Biancani, P.3
  • 140
    • 0027772534 scopus 로고
    • Interaction between signal transduction pathways contributing to gallbladder tonic contraction
    • Yu P, Harnett KM, Biancani P et al (1994) Interaction between signal transduction pathways contributing to gallbladder tonic contraction. Am J Physiol 265:1082-1089
    • (1994) Am J Physiol , vol.265 , pp. 1082-1089
    • Yu, P.1    Harnett, K.M.2    Biancani, P.3
  • 141
    • 0028784179 scopus 로고
    • Direct G protein activation reverses impaired CCK signaling in human gallbladders with cholesterol stones
    • Yu P, Chen Q, Harnett KM et al (1995) Direct G protein activation reverses impaired CCK signaling in human gallbladders with cholesterol stones. Am J Physiol 269:G659-665
    • (1995) Am J Physiol , vol.269
    • Yu, P.1    Chen, Q.2    Harnett, K.M.3
  • 142
    • 33746790607 scopus 로고    scopus 로고
    • Signal transduction pathways mediating CCK-induced gallbladder muscle contraction
    • Yu P, Chen Q, Xiao Z et al (1998) Signal transduction pathways mediating CCK-induced gallbladder muscle contraction. Am J Physiol 275:G203-211
    • (1998) Am J Physiol , vol.275
    • Yu, P.1    Chen, Q.2    Xiao, Z.3
  • 143
    • 0029447587 scopus 로고
    • Cholesterol gallstone formation in man and potential treatments of the gallbladder motility defect
    • Portincasa P, Stolk MF, van Erpecum KJ et al (1995) Cholesterol gallstone formation in man and potential treatments of the gallbladder motility defect. Scand J Gastroenterol Suppl 212:63-78
    • (1995) Scand J Gastroenterol Suppl , vol.212 , pp. 63-78
    • Portincasa, P.1    Stolk, M.F.2    Van Erpecum, K.J.3
  • 144
    • 0027312185 scopus 로고
    • Bile concentration promotes nucleation of cholesterol monohydrate crystals by increasing the cholesterol concentration in the vesicles
    • van Erpecum KJ, Stolk MFJ, van den Broek AMWC et al (1993) Bile concentration promotes nucleation of cholesterol monohydrate crystals by increasing the cholesterol concentration in the vesicles. Eur J Clin Invest 23:283-288
    • (1993) Eur J Clin Invest , vol.23 , pp. 283-288
    • Van Erpecum, K.J.1    Stolk, M.F.J.2    Van Den Broek, A.M.W.C.3
  • 145
    • 0026774738 scopus 로고
    • Patients with uncomplicated cholelithiasis acidify bile normally
    • Magnuson TH, Lillemoe KD, Zarkin BA et al (1992) Patients with uncomplicated cholelithiasis acidify bile normally. Dig Dis Sci 37:1517-1522
    • (1992) Dig Dis Sci , vol.37 , pp. 1517-1522
    • Magnuson, T.H.1    Lillemoe, K.D.2    Zarkin, B.A.3
  • 146
    • 21044451206 scopus 로고    scopus 로고
    • Expression and subcellular localization of the AQP8 and AQP1 water channels in the mouse gall-bladder epithelium
    • Calamita G, Ferri D, Bazzini C et al (2005) Expression and subcellular localization of the AQP8 and AQP1 water channels in the mouse gall-bladder epithelium. Biol Cell 97:415-423
    • (2005) Biol Cell , vol.97 , pp. 415-423
    • Calamita, G.1    Ferri, D.2    Bazzini, C.3
  • 147
    • 0022611081 scopus 로고
    • Gallbladder absorption increases during early cholesterol gallstone formation
    • Conter RL, Roslyn JJ, Porter-Fink V et al (1986) Gallbladder absorption increases during early cholesterol gallstone formation. Am J Surg 151:184-192
    • (1986) Am J Surg , vol.151 , pp. 184-192
    • Conter, R.L.1    Roslyn, J.J.2    Porter-Fink, V.3
  • 148
    • 0034053960 scopus 로고    scopus 로고
    • Impaired human gallbladder lipid absorption in cholesterol gallstone disease and its effect on cholesterol solubility in bile
    • Ginanni Corradini S, Elisei W, Giovannelli L et al (2000) Impaired human gallbladder lipid absorption in cholesterol gallstone disease and its effect on cholesterol solubility in bile. Gastroenterology 118:912-920
    • (2000) Gastroenterology , vol.118 , pp. 912-920
    • Ginanni Corradini, S.1    Elisei, W.2    Giovannelli, L.3
  • 149
    • 0032703390 scopus 로고    scopus 로고
    • Lipid absorption by the human gallbladder
    • Einarsson C (1999) Lipid absorption by the human gallbladder. Ital J Gastroenterol Hepatol 31:571-573
    • (1999) Ital J Gastroenterol Hepatol , vol.31 , pp. 571-573
    • Einarsson, C.1
  • 150
    • 0024443742 scopus 로고
    • Effect of dietary cholesterol on phosphatidylcholines and phosphatidylethanolamines in bile and gallbladder mucosa in the prairie dog
    • Booker ML, Scott TE, La Morte WW (1989) Effect of dietary cholesterol on phosphatidylcholines and phosphatidylethanolamines in bile and gallbladder mucosa in the prairie dog. Gastroenterology 97:1261-1267
    • (1989) Gastroenterology , vol.97 , pp. 1261-1267
    • Booker, M.L.1    Scott, T.E.2    La Morte, W.W.3
  • 151
    • 0027448262 scopus 로고
    • An explanation for gallstones in normal-weight women: Slow intestinal transit
    • Heaton KW, Emmett PM, Symes CL et al (1993) An explanation for gallstones in normal-weight women: slow intestinal transit. Lancet 341:8-10
    • (1993) Lancet , vol.341 , pp. 8-10
    • Heaton, K.W.1    Emmett, P.M.2    Symes, C.L.3
  • 153
    • 0034799084 scopus 로고    scopus 로고
    • Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: Soluble pronucleating proteins in gallbladder and hepatic biles
    • van Erpecum KJ, Wang DQH, Lammert F et al (2001) Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: soluble pronucleating proteins in gallbladder and hepatic biles. J Hepatol 35:444-451
    • (2001) J Hepatol , vol.35 , pp. 444-451
    • Van Erpecum, K.J.1    Wang, D.Q.H.2    Lammert, F.3
  • 154
    • 0029998921 scopus 로고    scopus 로고
    • Behavior of various cholesterol crystals in bile from gallstone patients
    • Portincasa P, van Erpecum KJ, Jansen A et al (1996) Behavior of various cholesterol crystals in bile from gallstone patients. Hepatology 23:738-748
    • (1996) Hepatology , vol.23 , pp. 738-748
    • Portincasa, P.1    Van Erpecum, K.J.2    Jansen, A.3
  • 155
    • 0029017084 scopus 로고
    • Increase of deoxycholate in supersaturated bile of patients with cholesterol gallstones disease and its correlation with de novo syntheses of cholesterol and bile acids in liver, gallbladder emptying, and small intestinal transit
    • Shoda J, He BF, Tanaka N et al (1995) Increase of deoxycholate in supersaturated bile of patients with cholesterol gallstones disease and its correlation with de novo syntheses of cholesterol and bile acids in liver, gallbladder emptying, and small intestinal transit. Hepatology 21:1291-1302
    • (1995) Hepatology , vol.21 , pp. 1291-1302
    • Shoda, J.1    He, B.F.2    Tanaka, N.3
  • 156
    • 17644406421 scopus 로고    scopus 로고
    • Octreotide induced prolongation of colonic transit increases faecal anaerobic bacteria, bile acid metabolising enzymes, and serum deoxycholic acid in patients with acromegaly
    • Thomas LA, Veysey MJ, Murphy GM et al (2005) Octreotide induced prolongation of colonic transit increases faecal anaerobic bacteria, bile acid metabolising enzymes, and serum deoxycholic acid in patients with acromegaly. Gut 54:630-635
    • (2005) Gut , vol.54 , pp. 630-635
    • Thomas, L.A.1    Veysey, M.J.2    Murphy, G.M.3
  • 157
    • 0033858091 scopus 로고    scopus 로고
    • Mechanism for the transit-induced increase in colonic deoxycholic acid formation in cholesterol cholelithiasis
    • Thomas LA, Veysey MJ, Bathgate T et al (2000) Mechanism for the transit-induced increase in colonic deoxycholic acid formation in cholesterol cholelithiasis. Gastroenterology 119:806-815
    • (2000) Gastroenterology , vol.119 , pp. 806-815
    • Thomas, L.A.1    Veysey, M.J.2    Bathgate, T.3
  • 158
    • 0029804227 scopus 로고    scopus 로고
    • Alpha-dehydroxylating bacteria enhance deoxycholic acid input and cholesterol saturation of bile in patients with gallstones
    • Berr F, Kullak-Ublick GA, Paumgartner G et al (1996) Alpha- dehydroxylating bacteria enhance deoxycholic acid input and cholesterol saturation of bile in patients with gallstones. Gastroenterology 111:1611-1620
    • (1996) Gastroenterology , vol.111 , pp. 1611-1620
    • Berr, F.1    Kullak-Ublick, G.A.2    Paumgartner, G.3
  • 159
    • 0344511817 scopus 로고    scopus 로고
    • Bile composition in inflammatory bowel disease: Ileal disease and colectomy, but not colitis, induce lithogenic bile
    • Pereira SP, Bain IM, Kumar D et al (2003) Bile composition in inflammatory bowel disease: ileal disease and colectomy, but not colitis, induce lithogenic bile. Aliment Pharmacol Ther 17:923-933
    • (2003) Aliment Pharmacol Ther , vol.17 , pp. 923-933
    • Pereira, S.P.1    Bain, I.M.2    Kumar, D.3
  • 160
    • 0033038816 scopus 로고    scopus 로고
    • Enterohepatic cycling of bilirubin: A putative mechanism for pigment gallstone formation in ileal Crohn's disease
    • Brink MA, Slors JF, Keulemans YC et al (1999) Enterohepatic cycling of bilirubin: a putative mechanism for pigment gallstone formation in ileal Crohn's disease. Gastroenterology 116:1420-1427
    • (1999) Gastroenterology , vol.116 , pp. 1420-1427
    • Brink, M.A.1    Slors, J.F.2    Keulemans, Y.C.3
  • 161
    • 33644805375 scopus 로고    scopus 로고
    • Helicobacter pylori and cholesterol gallstone formation in C57L/J mice: A prospective study
    • Maurer KJ, Rogers AB, Ge Z et al (2006) Helicobacter pylori and cholesterol gallstone formation in C57L/J mice: a prospective study. Am J Physiol Gastrointest Liver Physiol 290:G175-G182
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Maurer, K.J.1    Rogers, A.B.2    Ge, Z.3
  • 162
    • 17144405238 scopus 로고    scopus 로고
    • Identification of cholelithogenic enterohepatic helicobacter species and their role in murine cholesterol gallstone formation
    • Maurer KJ, Ihrig MM, Rogers AB et al (2005) Identification of cholelithogenic enterohepatic helicobacter species and their role in murine cholesterol gallstone formation. Gastroenterology 128:1023-1033
    • (2005) Gastroenterology , vol.128 , pp. 1023-1033
    • Maurer, K.J.1    Ihrig, M.M.2    Rogers, A.B.3
  • 163
    • 0031899969 scopus 로고    scopus 로고
    • Hepatic Helicobacter species identified in bile and gallbladder tissue from Chileans with chronic cholecystitis
    • Fox JG, Dewhirst FE, Shen Z et al (1998) Hepatic Helicobacter species identified in bile and gallbladder tissue from Chileans with chronic cholecystitis. Gastroenterology 114:755-763
    • (1998) Gastroenterology , vol.114 , pp. 755-763
    • Fox, J.G.1    Dewhirst, F.E.2    Shen, Z.3
  • 164
    • 11144318237 scopus 로고    scopus 로고
    • Prevention of cholesterol gallstone disease by FXR agonists in a mouse model
    • Moschetta A, Bookout AL, Mangelsdorf DJ (2004) Prevention of cholesterol gallstone disease by FXR agonists in a mouse model. Nat Med 10:1352-1358
    • (2004) Nat Med , vol.10 , pp. 1352-1358
    • Moschetta, A.1    Bookout, A.L.2    Mangelsdorf, D.J.3
  • 165
    • 25444521889 scopus 로고    scopus 로고
    • Overexpression of liver X receptor a (LXRa) enhance cholesterol (Ch) cholelithogenesis in gallstone-resistant AKR mice (abstract)
    • Wang HH, Wang DQH (2004) Overexpression of liver X receptor a (LXRa) enhance cholesterol (Ch) cholelithogenesis in gallstone-resistant AKR mice (abstract). Gastroenterology 126 [4, Suppl. 2]: A15-110
    • (2004) Gastroenterology , vol.126 , Issue.4 SUPPL. 2
    • Wang, H.H.1    Wang, D.Q.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.