Defect of multidrug-resistance 3 gene expression in a subtype of progressive familial intrahepatic cholestasis

Hepatology

Volumn 23, Issue 4, 1996, Pages 904-908

  Deleuze, Jean François ^a   Jacquemin, Emmanuel ^a,b   Dubuisson, Claire ^a,b   Cresteil, Danièle ^a   Dumont, Micheline ^c   Erlinger, Serge ^c   Bernard, Olivier ^a,b   Hadchouel, Michelle ^a,b  

^a INSERM   (France)

^b BICÊTRE HOSPITAL   (France)

^c BEAUJON HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; DNA; GAMMA GLUTAMYLTRANSFERASE; GLYCOPROTEIN P; MESSENGER RNA; PHOSPHOLIPID; PREDNISONE;

ADULT; ARTICLE; BILIARY EXCRETION; CASE REPORT; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENETIC DISORDER; HISTOLOGY; HUMAN; HUMAN TISSUE; INTRAHEPATIC CHOLESTASIS; LIPID BILE LEVEL; LIVER FUNCTION TEST; LIVER TRANSPLANTATION; MULTIDRUG RESISTANCE; NORTHERN BLOTTING; PRIORITY JOURNAL; SCHOOL CHILD;

EID: 0029990296     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.1996.v23.pm0008666348     Document Type: Article

References (9)

1. Roninson IB, Chin JE, Choi K, Gros P, Housman DE, Fojo A, Shen DW, et al. Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells. Proc Natl Acad Sci USA 1986;83:4538-4542.
2. Van der Bliek AM, Baas F, Ten Houge de Lange T, Kooiman PM, van der Velde-Koerts T, Borst P. The human MDR3 gene encodes a novel P-glycoprotein homologue and gave rise to alternatively spliced mRNAs in liver. EMBO J 1987;6:3325-3331.
3. Van der Bliek AM, Kooiman PM, Schneider C, Borst P. Sequence of mdr3 cDNA encoding a human P-glycoprotein. Gene 1988;71:401-411.
4. Van der Bliek AM, Van der Velde-Koerts T, Biedler JL, Meyers MB, Ozols RF, Hamilton TC, Joenje H, et al. Genes amplified and overexpressed in human multidrug-resistant cell lines. Cancer Res 1988;48:5927-5932.
5. Gros P, Raymond M, Bell J, Housman DE. Cloning and characterization of a second member of the mouse mdr gene family. Mol Cell Biol 1988;8:2770-2778.
6. Raymond M, Rose E, Housman DE, Gros P. Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug resistant cells. Mol Cell Biol 1990;10:1642-1651.
7. Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 1993;62:385-427.
8. Schinkel AH, Roelofs MEM, Borst P. Characterization of the human MDR3 P-glycoprotein and its recognition by P-glycoprotein-specific monoclonal antibodies. Cancer Res 1991;51:2628-2635.
9. Buschman E, Gros P. Functional analysis of chimeric genes obtained by exchanging homologous domains of the mouse mdr1 and mdr2 genes. Mol Cell Biol 1991;11:595-603.