CCK receptor dysfunction in muscle membranes from human gallbladders with cholesterol stones

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 276, Issue 6 39-6, 1999, Pages

  Xiao, Zuo Liang ^a   Chen, Qian ^a   Amaral, Joseph ^a   Biancani, Piero ^a   Jensen, Robert T ^b   Behar, Jose ^a,c  

^a BROWN UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c APC   (United States)

Author keywords

Cholecystokinin receptors; Liposomes; Smooth muscle

Indexed keywords

CHOLECYSTOKININ RECEPTOR; CHOLESTEROL; LIPOSOME; PHOSPHOLIPID;

ARTICLE; CHOLESTEROL STONE; DISSOCIATION CONSTANT; GALLBLADDER; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE FIBER MEMBRANE;

EID: 0032996629     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1999.276.6.g1401     Document Type: Article

References (28)

1. Behar, J., and P. Biancani. Pharmacologic characterization of excitatory and inhibitory cholecystokinin receptors of the cat gallbladder and sphincter of Oddi. Gastroenterology 92: 764-770, 1987.
2. Behar, J., K. Y. Lee, W. R. Thompson, and P. Biancani. Gallbladder contraction in patients with pigment and cholesterol stones. Gastroenterology 97: 1479-1484, 1989.
3. Behar, J., B. Y. Rhim, W. Thompson, and P. Biancani. Inositol triphosphate restores impaired human gallbladder motility associated with cholesterol stones. Gastroenterology 104: 563-568, 1993.
4. Blevins, G. T., E. M. van de Westerlo, C. D. Logsdon, P. M. Blevins, and J. A. Williams. Nucleotides regulate the binding affinity of the recombinant type A cholecystokinin receptor in CHO K1 cells. Regul. Pept. 61: 87-93, 1996.
5. Chen, Q., Z. L. Xiao, W. Cao, J. Amaral, P. Biancani, and J. Behar. Excessive membrane cholesterol alters muscle contractility and membrane fluidity in human gallbladders with gallstones. Gastroenterology 112, Suppl.: A711, 1997.
6. Corp, E. S., J. Mcquade, T. H. Moran, and G. P. Smith. Characterization of type A and type B CCK receptor binding sites in rat vagus nerve. Brain Res. 623: 161-166, 1993.
7. Fong, T. M., and M. G. Mcnamee. Stabilization of acetylcholine receptor secondary structure by cholesterol and negatively charged lipids. Biochemistry 26: 3871-3880, 1987.
8. Ghosh, C., R. M. Dick, and S. F. Ali. Iron/ascorbate-induced lipid peroxidation changes membrane fluidity and muscarinic cholinergic receptorbinding in rat frontal cortex. Neurochem. Int. 23: 479-484, 1993.
9. Gleason, M. M., M. S. Medow, and T. N. Tulenko. Excess membrane cholesterol alters calcium movements, cytosolic calcium levels, and membrane fluidity in arterial smooth muscle cells. Circ. Res. 69: 216-227, 1991.
10. Grider, J. R., and G. M. Makhlouf. Distinct receptors for cholecystokinin and gastrin on muscle cells of stomach and gallbladder. Am. J. Physiol. 259 (Gastrointest. Liver Physiol. 22): G184-G190, 1990.
11. Huang, S. C., K. P. Fortune, S. A. Wank, A. S. Kopin, and J. D. Gardner. Multiple affinity states of different cholecystokinin receptors. J. Biol. Chem. 269: 26121-26126, 1994.
12. James, R. U. P. P. J., W. H. Nealon, P. Singh, C. J. Fagan, A. S. Jonas, G. H. Greeley, and J. C. Thompson. Correlation of cholecystokinin receptors with gallbladder contractility in patients with gallstones. Ann. Surg. 205: 641-648, 1987.
13. Kiaii, B., Q. W. Xu, and E. A. Shaffer. Basis of impaired gallbladder contractility by progesterone in the guinea pig in vitro (Abstract). Gastroenterology 112: A1300, 1997.
14. Klein, I., L. Moore, and I. Pastan. Effect of liposomes containing cholesterol on adenylate cyclase activity of cultured mammalian fibroblasts. Biochim. Biophys. Acta 506: 42-53, 1978.
15. Munson, P. J., and D. Rodbard. Ligand, a versatile computerized approach for characterization of ligand-binding systems. Anal. Biochem. 107: 220-239, 1980.
16. Nardone, G., I. A. Ferber, and L. J. Miller. The integrity of the cholecystokinin receptor gene in gallbladder disease and obesity. Hepatology 22: 1751-1753, 1995.
17. Pellegrini, C. A., T. Ryan, W. Broderick, and L. W. Way. Gallbladder filling and emptying during cholesterol gallstone formation in the prairie dog. Gastroenterology 90: 143-149, 1986.
18. Reubi, J. C., B. Waser, U. Laderach, C. Stettler, H. Friess, F. Halter, and A. Schmassmann. Localization of cholecystokinin A and cholecystokinin B-gastrin receptors in the human stomach. Gastroenterology 112: 1197-1205, 1997.
19. Ross, P. E., A. N. Butt, and C. Gallacher. Cholesterol absorption by the gallbladder. J. Clin. Pathol. 43: 572-575, 1990.
20. Schjoldager, B., X. Molero, and L. J. Miller. Functional and biochemical characterization of the human gallbladder muscularis cholecystokinin receptor. Gastroenterology 96: 1119-1125, 1989.
21. Schroeder, F., J. R. Jefferson, A. B. Kier, J. Knittel, T. J. Scallen, W. G. Wood, and I. Hapala. Membrane cholesterol dynamics: cholesterol domains and kinetic pools. Proc. Soc. Exp. Biol. Med. 196: 235-252, 1991.
22. Shaw, M. J., E. M. Hadac, and L. J. Miller. Preparation of enriched plasma membrane from bovine gallbladder muscularis for characterization of cholecystokinin receptors. J. Biol. Chem. 29: 14313-14318, 1987.
23. 3H) cholesterol between lipid vesicles and rat arterial smooth muscle cells in vitro. Biochim. Biophys. Acta 750: 434-439, 1983.
24. Tokunaga, Y., K. L. Cox, R. Coleman, W. Concepcion, P. Nakazato, and C. O. Esquivel. Characterization of cholecystokinin receptors on the human gallbladder. Surgery 113: 155-162, 1993.
25. Wess, J. Molecular basis of muscarinic acetylcholine receptor function. Trends Pharmacol. Sci. 14: 308-313, 1993.
26. Yu, P., Q. Chen, P. Biancani, and J. Behar. Membrane cholesterol alters gallbladder muscle contractility in prairie dogs. Am. J. Physiol. 271 (Gastrointest. Liver Physiol. 34): G56-G61, 1996.
27. Yu, P., Q. Chen, K. M. Harnett, J. Amaral, P. Biancani, and J. Behar. Direct G protein activation reverses impaired CCK-signaling in human gallbladders with cholesterol stones. Am. J. Physiol. 269 (Gastrointest. Liver Physiol. 32): G659-G665, 1995.
28. Zhang, L., B. Horowitz, and I. L. O. Buxton. Muscarinic receptors in canine colonic circular smooth muscle. 1. Coexistence of M2 and M3 subtypes. Mol. Pharmacol. 40: 943-951, 1991.