Isolation and characterization of patient-derived, toxic, high mass Amyloid β-protein (Aβ) assembly from Alzheimer disease brains

Journal of Biological Chemistry

Volumn 284, Issue 47, 2009, Pages 32895-32905

  Noguchi, Akihiko ^a   Matsumura, Satoko ^a   Dezawa, Mari ^b,c   Tada, Mari ^d   Yanazawa, Masako ^a   Ito, Akane ^a   Akioka, Manami ^a   Kikuchi, Satoru ^a   Sato, Michio ^a   Noda, Munehiro ^e   Fukunari, Atsusbi ^e   Muramatsu, Shin Ichi ^f   Itokazu, Yutaka ^b   Sato, Kazuki ^g   Takahashi, Hitoshi ^d   Teplow, David B ^h   Nabeshima, Yo Ichi ^b   Kakita, Akiyoshi ^d   Imahori, Kazutomo ⁱ   Hoshi, Minako ^a,b,j  

^a MITSUBISHI KAGAKU INSTITUTE OF LIFE SCIENCES   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

^d NIIGATA UNIVERSITY   (Japan)

^e MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^f JICHI MEDICAL UNIVERSITY   (Japan)

^g FUKUOKA WOMEN'S UNIVERSITY   (Japan)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ UNIVERSITY OF TOKYO   (Japan)

^j NONE

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; DIFFERENT MECHANISMS; IMMUNO-ISOLATION; IN-VITRO; ISOLATION AND CHARACTERIZATION; LEWY BODIES; MOLECULAR BASIS; NEURODEGENERATION; NEURODEGENERATIVE DISEASE; NEURONAL LOSS; NEUROTOXICITY; PRESYNAPTIC; SYNAPTIC TRANSMISSION; TERTIARY STRUCTURES;

ANTIBODIES; GLYCOPROTEINS; NEURONS; OLIGOMERS; TARGETS; TOXICITY;

SURFACE STRUCTURE;

AMYLOID BETA PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; AMYLOSPHEROID CELL; ANIMAL CELL; ANIMAL TISSUE; ANTIBODY ISOLATION; ANTIBODY SPECIFICITY; ARTICLE; BINDING AFFINITY; CELL MATURATION; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFUSE LEWY BODY DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOISOLATION; IMMUNOSPECIFICITY; IN VITRO STUDY; LIGAND BINDING; MOLECULAR WEIGHT; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN TERTIARY STRUCTURE; SPHEROID CELL; SYNAPTIC TRANSMISSION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; BRAIN; DIMERIZATION; HUMANS; LEWY BODIES; MODELS, BIOLOGICAL; NEURONS; PEPTIDE FRAGMENTS; PEPTIDES; PHENOTYPE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, METABOTROPIC GLUTAMATE; SYNAPTIC TRANSMISSION;

EID: 70450257636     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.000208     Document Type: Article

References (65)

1. Ross, C. A., and Poirier, M. A. (2005) Nat. Rev. Mol. Cell Biol. 6, 891-898
2. Selkoe, D. J. (1991) Neuron 6, 487-498
3. Lansbury, P. T., and Lashuel, H. A. (2006) Nature 443, 774-779
4. Iwatsubo, T. (2007) Neuropathology 27, 474-478
5. Soto, C., and Estrada, L. D. (2008) Arch. Neurol. 65, 184-189
6. Chiti, F., and Dobson, C. M. (2009) Nat. Chem. Biol. 5, 15-22
7. Hardy, J., and Selkoe, D. J. (2002) Science 297, 353-356
8. Tanzi, R. E., and Bertram, L. (2005) Cell 120, 545-555
9. Saido, T. C., and Iwata, N. (2006) Neurosci. Res. 54, 235-253
10. Klein, W. L., Stine, W. B., Jr., and Teplow, D. B. (2004) Neurobiol. Aging 25, 569-580
11. Walsh, D. M., and Selkoe, D. J. (2007) J. Neurochem. 101, 1172-1184
12. Glabe, C. G. (2008) J. Biol. Chem. 283, 29639-29643
13. Roychaudhuri, R., Yang, M., Hoshi, M. M., and Teplow, D. B. (2009) J. Biol. Chem. 284, 4749-4753
14. Walsh, D. M., Lomakin, A., Benedek, G. B., Condron, M. M., and Teplow, D. B. (1997) J. Biol. Chem. 272, 22364-22372
15. Podlisny, M. B., Ostaszewski, B. L., Squazzo, S. L., Koo, E. H., Rydell, R. E., Teplow, D. B., and Selkoe, D. J. (1995) J. Biol. Chem. 270, 9564-9570
16. Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Rozovsky, I., Trommer, B., Viola, K. L., Wals, P., Zhang, C., Finch, C. E., Krafft, G. A., and Klein, W. L. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 6448-6453
17. Barghorn, S., Nimmrich, V., Striebinger, A., Krantz, C., Keller, P., Janson, B., Bahr, M., Schmidt, M., Bitner, R. S., Harlan, J., Barlow, E., Ebert, U., and Hillen, H. (2005) J. Neurochem. 95, 834-847
18. Lesné, S., Koh, M. T., Kotilinek, L., Kayed, R., Glabe, C. G., Yang, A., Gallagher, M., and Ashe, K. H. (2006) Nature 440, 352-357
19. Deshpande, A., Mina, E., Glabe, C., and Busciglio, J. (2006) J. Neurosci. 26, 6011-6018
20. Chimon, S., Shaibat, M. A., Jones, C. R., Calero, D. C., Aizezi, B., and Ishii, Y. (2007) Nat. Struct. Mol. Biol. 14, 1157-1164
21. Lacor, P. N., Buniel, M. C., Chang, L., Fernandez, S. J., Gong, Y., Viola, K. L., Lambert, M. P., Velasco, P. T., Bigio, E. H., Finch, C. E., Krafft, G. A., and Klein, W. L. (2004) J. Neurosci. 24, 10191-10200
22. Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., and Glabe, C. G. (2003) Science 300, 486-489
23. Lacor, P. N., Buniel, M. C., Furlow, P. W., Clemente, A. S., Velasco, P. T., Wood, M., Viola, K. L., and Klein, W. L. (2007) J. Neurosci. 27, 796-807
24. Shankar, G. M., Bloodgood, B. L., Townsend, M., Walsh, D. M., Selkoe, D. J., and Sabatini, B. L. (2007) J. Neurosci. 27, 2866-2875
25. Cleary, J. P., Walsh, D. M., Hofmeister, J. J., Shankar, G. M., Kuskowski, M. A., Selkoe, D. J., and Ashe, K. H. (2005) Nat. Neurosci. 8, 79-84
26. Ashe, K. H. (2001) Learn Mem. 8, 301-308
27. Hock, B. J., Jr., and Lamb, B. T. (2001) Trends Genet. 17, S7-S12
28. Calhoun, M. E., Wiederhold, K. H., Abramowski, D., Phinney, A. L., Probst, A., Sturchler-Pierrat, C., Staufenbiel, M., Sommer, B., and Jucker, M. (1998) Nature 395, 755-756
29. Bondolfi, L., Calhoun, M., Ermini, F., Kuhn, H. G., Wiederhold, K. H., Walker, L., Staufenbiel, M., and Jucker, M. (2002) J. Neurosci. 22, 515-522
30. Shankar, G. M., Li, S., Mehta, T. H., Garcia-Munoz, A., Shepardson, N. E., Smith, I., Brett, F. M., Farrell, M. A., Rowan, M. J., Lemere, C. A., Regan, C. M., Walsh, D. M., Sabatini, B. L., and Selkoe, D. J. (2008) Nat. Med. 14, 837-842
31. Kuo, Y. M., Emmerling, M. R., Vigo-Pelfrey, C., Kasunic, T. C., Kirkpatrick, J. B., Murdoch, G. H., Ball, M. J., and Roher, A. E. (1996) J. Biol. Chem. 271, 4077-4081
32. Lue, L. F., Kuo, Y. M., Roher, A. E., Brachova, L., Shen, Y., Sue, L., Beach, T., Kurth, J. H., Rydel, R. E., and Rogers, J. (1999) Am. J. Pathol. 155, 853-862
33. McLean, C. A., Cherny, R. A., Fraser, F. W., Fuller, S. J., Smith, M. J., Beyreuther, K., Bush, A. I., and Masters, C. L. (1999) Ann. Neurol. 46, 860-866
34. Gómez-Isla, T., Hollister, R., West, H., Mui, S., Growdon, J. H., Petersen, R. C., Parisi, J. E., and Hyman, B. T. (1997) Ann. Neurol. 41, 17-24
35. Morrison, J. H., and Hof, P. R. (1997) Science 278, 412-419
36. Larrieu, S., Letenneur, L., Orgogozo, J. M., Fabrigoule, C., Amieva, H., Le Carret, N., Barberger-Gateau, P., and Dartigues, J. F. (2002) Neurology 59, 1594-1599
37. Bouwman, F. H., Schoonenboom, S. N., van der Flier, W. M., van Elk, E. J., Kok, A., Barkhof, F., Blankenstein, M. A., and Scheltens, P. (2007) Neurobiol. Aging 28, 1070-1074
38. Hoshi, M., Sato, M., Matsumoto, S., Noguchi, A., Yasutake, K., Yoshida, N., and Sato, K. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 6370-6375
39. Lomakin, A., Chung, D. S., Benedek, G. B., Kirschner, D. A., and Teplow, D. B. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 1125-1129
40. Demuro, A., Mina, E., Kayed, R., Milton, S. C., Parker, I., and Glabe, C. G. (2005) J. Biol. Chem. 280, 17294-17300
41. Kuwano, R., Miyashita, A., Arai, H., Asada, T., Imagawa, M., Shoji, M., Higuchi, S., Urakami, K., Kakita, A., Takahashi, H., Tsukie, T., Toyabe, S., Akazawa, K., Kanazawa, I., and Ihara, Y. (2006) Hum. Mol. Genet. 15, 2170-2182
42. Kayed, R., Head, E., Sarsoza, F., Saing, T., Cotman, C. W., Necula, M., Margol, L., Wu, J., Breydo, L., Thompson, J. L., Rasool, S., Gurlo, T., Butler, P., and Glabe, C. G. (2007) Mol. Neurodegener. 2, 18
43. Mirra, S. S., Heyman, A., McKeel, D., Sumi, S. M., Crain, B. J., Brownlee, L. M., Vogel, F. S., Hughes, J. P., van Belle, G., and Berg, L. (1991) Neurology 41, 479-486
44. Li, Y. T., Woodruff-Pak, D. S., and Trojanowski, J. Q. (1994) Neurobiol. Aging 15, 1-9
45. Kepe, V., Huang, S. C., Small, G. W., Satyamurthy, N., and Barrio, J. R. (2006) Methods Enzymol. 412, 144-160
46. Ince, P. G., and McKeith, I. G. (2003) in Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders (Dickson, D., ed) pp. 188-197, ISN Neuropath Press, Basel
47. Giasson, B. I., Lee, V. M.-Y., and Trojanowski, J. Q. (2004) in The Neuropathology of Dementia (Esiri, M., Lee, V. M.-Y., and Trojanowski, J. Q., eds) 2nd Ed., pp. 353-375, Cambridge University Press, Cambridge
48. Kosaka, K. (1990) J. Neurol. 237, 197-204
49. Dezawa, M., Kanno, H., Hoshino, M., Cho, H., Matsumoto, N., Itokazu, Y., Tajima, N., Yamada, H., Sawada, H., Ishikawa, H., Mimura, T., Kitada, M., Suzuki, Y., and Ide, C. (2004) J. Clin. Invest. 113, 1701-1710
50. De Felice, F. G., Velasco, P. T., Lambert, M. P., Viola, K., Fernandez, S. J., Ferreira, S. T., and Klein, W. L. (2007) J. Biol. Chem. 282, 11590-11601
51. Zhao, W. Q., De Felice, F. G., Fernandez, S., Chen, H., Lambert, M. P., Quon, M. J., Krafft, G. A., and Klein, W. L. (2008) FASEB J. 22, 246-260
52. Khosravani, H., Zhang, Y., Tsutsui, S., Hameed, S., Altier, C., Hamid, J., Chen, L., Villemaire, M., Ali, Z., Jirik, F. R., and Zamponi, G. W. (2008) J. Cell Biol. 181, 551-565
53. Laurén, J., Gimbel, D. A., Nygaard, H. B., Gilbert, J. W., and Strittmatter, S. M. (2009) Nature 457, 1128-1132
54. Klein, W. L., Krafft, G. A., and Finch, C. E. (2001) Trends Neurosci. 24, 219-224
55. Bucciantini, M., Giannoni, E., Chiti, F., Baroni, F., Formigli, L., Zurdo, J., Taddei, N., Ramponi, G., Dobson, C. M., and Stefani, M. (2002) Nature 416, 507-511
56. Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., and Selkoe, D. J. (2002) Nature 416, 535-539
57. Dickson, D. W., and Yen, S. H. (1989) Neurobiol. Aging 10, 402-414
58. Terry, R. D., Masliah, E., Salmon, D. P., Butters, N., DeTeresa, R., Hill, R., Hansen, L. A., and Katzman, R. (1991) Ann. Neurol. 30, 572-580
59. Thal, D. R., Rüb, U., Orantes, M., and Braak, H. (2002) Neurology 58, 1791-1800
60. Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F., and Cole, G. (1996) Science 274, 99-102
61. Kawarabayashi, T., Younkin, L. H., Saido, T. C., Shoji, M., Ashe, K. H., and Younkin, S. G. (2001) J. Neurosci. 21, 372-381
62. Casas, C., Sergeant, N., Itier, J. M., Blanchard, V., Wirths, O., van der Kolk, N., Vingtdeux, V., van de Steeg, E., Ret, G., Canton, T., Drobecq, H., Clark, A., Bonici, B., Delacourte, A., Benavides, J., Schmitz, C., Tremp, G., Bayer, T. A., Benoit, P., and Pradier, L. (2004) Am. J. Pathol. 165, 1289-1300
63. Oakley, H., Cole, S. L., Logan, S., Maus, E., Shao, P., Craft, J., Guillozet-Bongaarts, A., Ohno, M., Disterhoft, J., Van Eldik, L., Berry, R., and Vassar, R. (2006) J. Neurosci. 26, 10129-10140
64. Pérez, M., Ribe, E., Rubio, A., Lim, F., Morán, M. A., Ramos, P. G., Ferrer, I., Isla, M. T., and Avila, J. (2005) Neuroscience 130, 339-347
65. Wilcock, D. M., Gharkholonarehe, N., Van Nostrand, W. E., Davis, J., Vitek, M. P., and Colton, C. A. (2009) J. Neurosci. 29, 7957-7965