Antioxidant and vasorelaxant activities of the Turraeanthus africanus methanol extract

Pharmaceutical Biology

Volumn 47, Issue 12, 2009, Pages 1123-1129

  Dongmo, Alain Bertand ^a   Dzikouk, Guillaume Dzissin ^b   Massoma, Dieudonné Lembé ^a   Nguelefak, Télesphore Benot ^c   Vardamides, Catherine Juliette ^a   Kamanyi, Albert ^c   Vierling, Wolfgang ^d  

^a UNIVERSITY OF DOUALA   (Cameroon)

^b UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^c UNIVERSITY OF DSCHANG   (Cameroon)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Antioxidant activity; Turraeanthus africanus; Vasorelaxant activity

Indexed keywords

CARDIOVASCULAR AGENT; METHANOL; NIFEDIPINE; PLANT EXTRACT; TURRAEANTHUS AFRICANUS EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BARK; CARDIOVASCULAR DISEASE; CONCENTRATION RESPONSE; DRUG DETERMINATION; DRUG INHIBITION; DRUG SYNTHESIS; ELECTROSTIMULATION; FEMALE; MALE; MEDICINAL PLANT; NONHUMAN; PLANT STEM; RAT; THIN LAYER CHROMATOGRAPHY; TURRAEANTHUS AFRICANUS; VASCULAR RING; VASODILATATION;

CAVIA; MELIACEAE;

EID: 70450199368     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880200903008674     Document Type: Article

References (33)

1. Ajay M, Gilani AH, Mustafa MR (2003): Effects of flavonoids on vascular smooth muscle of the isolated rat thoracic aorta. Life Sci 74: 603-612.
2. Andre E, Malheiros A, Cechinel-Filho V, Yunes RA, Calixto JB (1999): Mechanisms underlying the relaxation caused by the sesquiterpene polygodial in vessels from rabbit and guinea-pig. Eur J Pharmacol 10: 47-53.
3. Aruoma OI (1998): Free radicals, oxidative stress, and antioxidants in human health and disease. J Am Oil Chem Soc 75: 199-212.
4. Ayafor JF, Kimbu SF, Ngadjui BT, Akam TM, Dongo E, Sondengam BL, Connolly JD, Rycroft DS (1994): Limonoids from Carapa grandiflora (Meliaceae). Tetrahedron 50: 9343-9354.
5. Backhouse N, Rosales L, Apablaza C, Göity L, Erazo S, Negrete R., Theodoluz C, Rodriguez J, Delporte C (2008): Analgesic, antiinflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae. J Ethnopharmacol 116: 263-269.
6. Bülbring E, Tomita T (1987): Catecholamine action on smooth muscle. Pharmacol Rev 39: 49-96.
7. Dongmo AB, Nguelefack T, Lacaille-Dubois MA (2005): Antinociceptive and anti-inflammatory activities of Acacia pennata Willd (Mimosaceae). J Ethnopharmacol 98: 201-206.
8. Dongmo AB, Azebaze AGB, Meyer M, Sontia B, Ouahouo B, Nkengfack AE, Vierling W (2007): Vasodilator effect of the extracts and some coumarins from the stem bark of Mammea africana (Guttiferae). J Ethnopharmacol 111: 329-334.
9. Duarte DF, Sant'Ana AE, Calixto JB (1992): Analysis of the vasorelaxant action of jatrophone in the isolated aorta of the rat: Influence of potassium channel blockers. Eur J Pharmacol 29: 75-81.
10. Gao J, Chen J, Tang X, Pan L, Xu L, Zhao L, Xu Q (2006): Mechanism underlying mitochondrial protection of asiatic acid against hepatotoxicity in mice. J Pharm Pharmacol 58: 227-233.
11. Guerrero MF, Puebla P, Carron R, Martin ML, San Roman L (2004): Vasorelaxant effect of new neo-clerodane diterpenoids isolated from Croton schiedeanus. J Ethnopharmacol 94: 185-189.
12. Karaky H, Weiss GB (1984): Calcium channels in smooth muscle. Gastroenterology 87: 960-970.
13. Kaiser J (1990): Wood of the month - avodire: The light African wood with hidden strength. In: Kaiser J, ed., Wood of the Month, Supplement to Wood and Wood Products. New York, p. 22.
14. Kimbu SF, Ayafor JF, Sondengam BL, Tsamo E, Connolly JD, Rycroft DS (1984): Carapolides D, E, F, novel tetranortriterpenoids from the seeds of Carapa grandiflora (Meliaceae). Tetrahedron Lett 25: 1617-1620.
15. Kizil G, Kizil M, Yavuz M, Emen S, Hakimoglu F (2008): Antioxidant activities of ethanol extracts of Hypericum triquetrifolium and Hypericum scabroides. Pharm Biol 46: 231-242.
16. Kline M (1979): Turraeanthus africanus - Avodire. In: Flynn JH, ed., A Guide to Useful Woods of the World. Portland, ME, King Philip Publishing Co., p. 354.
17. Masuda T, Inaba Y, Maekawa T, Takeda Y, Yamaguchi H, Nakamoto K, Kuninaga H, Nishizato S, Nonaka A (2003): Simple detection method of powerful antiradical compounds in the raw extract of plants and its application for the identification of antiradical plants constituents. J Agr Food Chem 51: 1831-1838.
18. Nakano D, Takaoka M, Kiso Y, Matsumura Y (2004): Antihypertensive effect of sesamin. Vasc Dis Prev 1: 233-241.
19. Nakano D, Kwak CJ, Fujii K, Ikemura K, Satake A, Ohkita M, Takaoka M, Ono Y, Nakai M, Tomimori N, Kiso Y, Matsumura Y (2006): Sesamin metabolites induce an endothelial nitric oxide- dependent vasorelaxation through their antioxidative property-independent mechanisms: Possible involvement of the metabolites in the antihypertensive effect of sesamin. J Pharmacol Exp Ther 318: 328-335.
20. Reiter M (1981): The use of the isolated papillary muscle for the evaluation of positive inotropic effects of cardioactive steroids. In: Greef K, ed., Handbook of Experimental Pharmacology. Berlin, Springer-Verlag, p. 153.
21. Rodriguez-Cruz ME, Pérez-Ordaz L, Serrato-Barajas BE, Juárez- Oropeza MA, Mascher D, Paredes-Carbajal MC (2003): Endothelium-dependent effects of the ethanolic extract of the mistletoe Psittacanthus calyculatus on the vasomotor responses of rat aortic rings. J Ethnopharmacol 83: 213-218.
22. Rubanyi GM (1993): The role of endothelium in cardiovascular homeostasis and diseases. J Cardiovasc Pharmacol 22: S1-S14.
23. Sautour M, Mitaine-Offer AC, Miyamoto T, Dongmo A, Lacaille- Dubois MA (2004): Antifungal steroid saponins from Dioscorea cayenensis. Planta Med 70: 90-92.
24. Shilpi JA, Taufiq-Ur-Rahman M, Uddin SJ, Alam MS, Sadhu SK, Seidel V (2006): Preliminary pharmacological screening of Bixa orellana L. leaves. J Ethnopharmacol 108: 264-271.
25. Steinmetz KA, Potter JD (1996): Vegetables, fruit, and cancer prevention: a review. J Am Diet Assoc 96: 1027-1039.
26. Tane P, Akam MT, Tsopmo A, Ndi CP, Sterner O (2004): Two labdane diterpenoids and a seco-tetranortriterpenoid from Turraeanthus africanus. Phytochemistry 65: 3083-3087.
27. Thaipong K, Boonprakob U, Cisneros-Zevallos L, Byrne DH (2005): Hydrophilic and lipophilic antioxidant activities of guava fruits. Southeast Asian J Trop Med Public Health 36: 254-257.
28. Tongo J, Ekwalla E (2003): Nos plantes qui soignent Centre Spirituel de Rencontre. Basel, Switzerland, Roche, p. 38.
29. Vardamides JC, Dongmo AB, Ndom JC, Azebaze AGB, Zounda MRS, Nkengfack AE, Ngando TM, Fomum ZT, Meyer M (2006): Alkaloids from the stem bark of Turraeanthus africanus (Welw. Ex. C.D.C.) Pellegr. Chem Pharm Bull 54: 1034-1036.
30. Wagner H, Bladt S (1996): Plant Drug Analysis, 2nd ed. Berlin, Springer-Verlag, pp. 360-362.
31. Xiong Q, Kadota S, Tani T, Namba T (1996): Antioxidative effects of phenylethanoids from Cistanche deserticola. Biol Pharm Bull 19: 1580-1585.
32. Yan X, Nagata T, Fa X (1998): Antioxidative activities in some common seaweeds. Plant Foods Hum Nutr 52: 253-262.
33. Yoshikawa M, Shimada H, Matsuda H, Yamahara J, Murakami N (1996): Bioactive constituents of Chinese natural medicines. I. New sesquiterpene ketones with vasorelaxant effect from Chinese moxa, the processed leaves of Artemisia argyi Levl. et Vant.: Moxartenone and moxartenolide. Chem Pharm Bull 44: 1656-1662.