Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae

Journal of Ethnopharmacology

Volumn 116, Issue 2, 2008, Pages 263-269

  Backhouse, N ^a   Rosales, L ^a   Apablaza, C ^a   Goity L ^c   Erazo, S ^a   Negrete, R ^a   Theodoluz, C ^b   Rodriguez J ^b   Delporte, C ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSIDAD DE TALCA   (Chile)

^c NONE

Author keywords

Analgesic; Anti inflammatory; Antioxidant; Buddleja globosa; Buddlejaceae; Flavonoids; Phenylethanoids; Sterols; Triterpenoids

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 12 DEOXYPHORBOL 13 DECANOATE; ACTEOSIDE; ALLOPURINOL; ALPHA AMYRIN; APIGETRIN; ARACHIDONIC ACID; BETA AMYRIN; BETA SITOSTEROL GLYCOSIDE; BUDDLEJA GLOBOSA EXTRACT; CAMPESTEROL; DICHLOROMETHANE; FREE RADICAL; GLYCOSIDE; HEXANE; INDOMETACIN; LIPID; LUTEOLIN 7 GLUCOSIDE; METHANOL; NAPROXEN; NIMESULIDE; PHORBOL DERIVATIVE; PLANT EXTRACT; QUERCETIN; SITOSTANOL; SITOSTEROL; STIGMASTEROL; SUPEROXIDE; UNCLASSIFIED DRUG; XANTHINE OXIDASE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BUDDLEJA; BUDDLEJA GLOBOSA; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; ENZYME INHIBITION; FEMALE; FRACTIONATION; GUINEA PIG; LIPID PEROXIDATION; MALE; NONHUMAN; PAIN; PAW EDEMA; PROTON NUCLEAR MAGNETIC RESONANCE; TRADITIONAL MEDICINE; VALIDATION PROCESS; WRITHING TEST;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; BUDDLEJA; FEMALE; MALE; MICE; PLANT EXTRACTS; SPECTRUM ANALYSIS;

BUDDLEJA GLOBOSA; SCROPHULARIACEAE;

EID: 39149135229     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2007.11.025     Document Type: Article

References (44)

1. Awad A.B., Burr A.T., and Fink C.S. Effect of resveratrol and beta-sitosterol in combination on reactive oxygen species and prostaglandin release by PC-3 cells. Prostaglandins, Leukotrienes, and Essential Fatty Acids 72 (2005) 219-226
2. Backhouse N., Delporte C., Negrete R., Suárez S., Cassels B.K., Breitmaier E., and Schneider C. Anti-inflammatory and antypiretic metabolites of Acaena splendens. International Journal of Pharmacognosy 35 (1997) 1-6
3. Backhouse N., Delporte C., Negrete R., San Feliciano S.A., and López-Pérez J.L. Bioactive phenolic derivatives from Acaena splendens methanol extract. Phytotherapy Research 16 (2002) 562-566
4. Brinker A.M., Ma J., Lipsky P.E., and Raskin I. Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae). Phytochemistry 68 (2007) 732-766
5. Chiou W.F., Lin L.C., and Chen C.F. Acteoside protects endothelial cells against free radical-induced oxidative stress. Journal of Pharmacy and Pharmacology 56 (2004) 743-748
6. Das D.K., and Maulik N. Antioxidant effectiveness in ischemia-reperfusion tissue injury. Methods in Enzymology 233 (1994) 601-610
7. De Azevedo M.B., Alderete J., Rodríguez J.A., Souza A.O., Rettori D., Torsoni M., Faljoni-Alario A., Haun M., and Duran N. Biological activities of new antitumoral of indole derivatives in an inclusion complex with cyclodextrin. Journal of Inclusion Phenomena and Macrocyclic Chemistry 37 (2000) 93-101
8. De la Puerta R., Martìnez-Domínguez E., and Ruíz-Gutiérrez V. Effect of minor components of virgin olive oil on topical anti-inflamatory assays. Zeitschrift für Naturforschung [C] 5 (2002) 147-152
9. Delporte C., Muñoz O., Rojas J., Ferrándiz M., Payá M., Erazo S., Maldonado S., Negrete R., San Feliciano A., and Backhouse N. Pharmaco-toxicological study of Kageneckia oblonga, Rosaceae. Zeitschrift für Naturforschung [C] 57 (2002) 100-108
10. Delporte C., Backhouse N., Erazo S., Negrete R., Vidal P., Silva X., López-Pérez J.L., San Feliciano A., and Muñoz O. Analgesic-anti-inflammatory properties of Proustia pyrifolia. Journal of Ethnopharmacology 99 (2005) 119-124
11. Ende C., and Gerbhardt R. Inhibition of matrix metalloproteinase-2 and -9 activities by selected flavonoids. Planta Medica 70 (2004) 1006-1008
12. Feresin G.E., Tapia A., Gutiérrez R.A., Delporte C., Backhouse N., and Schmeda-Hirschmann G. Free radical scavengers, anti-inflammatory and analgesic activity of Acaena magellanica. Journal of Pharmacy and Pharmacology 54 (2002) 835-844
13. García M.D., Sáenz M.T., Gómez M.A., and Fernández M.A. Topical anti-inflammatory activity of phytosterols isolated from Eryngium foetidum on chronic and acute inflammation models. Phytotherapy Research 13 (1999) 78-80
14. Harborne J.B., and Mabry T.J. The Flavonoids: Advances in Research (1982), Chapman and Hall, London, New York 744 pp.
15. Harris G.K., Qian Y., Leonard S.S., Sbarra D.C., and Shi X. Luteolin and chrysin differentially inhibit cyclooxygenase-2 expression and scavenge reactive oxygene species but similarly inhibit prostaglandin-E2 formation RAW 264.7 cells. Journal of Nutrition 136 (2006) 1517-1521
16. Hollander M., and Wolfe D.A. Nonparametric Statistical Methods. 2nd ed. (1999), John Wiley and Sons, New York pp. 106-140
17. Houghton P.J., Hylands P.J., Mensah A.Y., Hensel A., and Deters A.M. In vitro tests and ethnopharmacological investigations: wound healing as an example. Journal of Ethnopharmacology 100 (2005) 100-107
18. Jalil S., Mikhova B., Taskova R., Mitova M., Duddeck H., Choudhary M.I., and Rahman A.-U. In vitro anti-inflammatory effect of Carthamus lanatus L. Zeitschrift für Naturforschung [C] 58 (2003) 830-832
19. Karliner J., and Djerassi C. Terpenoids LVII. Mass spectral and nuclear magnetic resonance studies of pentacyclic triterpene hydrocarbons. Journal of Organic Chemistry 31 (1966) 1945-1956
20. Kim S.S., Son Y.O., Chun J.C., Kim S.E., Chung G.H., Hwang K.J., and Lee L.C. Antioxidant property of an active component purified from leaves of paraquat-tolerant Rhemannia glutinosa. Redox Report 10 (2005) 11-318
21. Kim H.P., Son K.H., Chang H.W., and Kang S.S. Anti-inflammatory plant flavonoids and cellular mechanisms. Journal of Pharmacological Sciences 96 (2004) 229-245
22. Kobori M., Yohishida M., Ohnishi-Kameyama M., and Shinmoto H. Ergosterol peroxide from an edible mushroom suppresses inflammatory responses in RAW264.7 macrophages and growth of HT29 colon adenocarcinoma cells. British Journal of Pharmacology 150 (2007) 209-219
23. Lee J.Y., Woo E., and Kang K.W. Inhibition of lipopolysaccharide-inducible nitric oxide synthase expression by acteoside through blocking of AP-1 activation. Journal of Ethnopharmacology 97 (2005) 561-566
24. Li L., Tsao R., Liu Z., Liu S., Yang R., Young J.C., Zhu H., Deng Z., Xie M., and Fu Z. Isolation and purification of acteoside and isoacteoside from Plantago psyllium L., by high speed counter-current chromatography. Journal of Chromatography A 1063 (2005) 161-169
25. Liao Y.H., Houghton P.J., and Hoult J.R. Novel and known constituents from Buddleja species and their activity against leukocyte eicosanoid generation. Journal of Natural Products 62 (1999) 1241-1245
26. Lin C.-M., Chen C.-S., Chen C.-T., Liang Y.-C., and Lin J.-K. Molecular modelling of flavonoids that inhibits xanthine oxidase. Biochemical and Biophysical Research Communications 294 (2002) 167-172
27. Liu M.J., Li J.X., Guo H.Z., Lee K.M., Qin L., and Chan K.M. The effects of verbascoside on plasma lipid peroxidation level and erythrocyte membrane fluidity during immobilization in rabbits: a time course study. Life Sciences 73 (2003) 883-892
28. Lloret S., and Moreno J.J. Effects of an anti-inflammatory peptide (antiflammin 2) on cell influx, eicosanoid biosynthesis and oedema formation by arachidonic acid and tetradecanoyl) phorbol dermal application. Biochemical Pharmacology 50 (1995) 347-353
29. Mathiesen L., Malterud FK.E., and Sund R.B. Antioxidant activity of fruit exudate and C-methylated dihydrochalcones from Myrica gale. Planta Medica 61 (1995) 515-518
30. Masaki H., Sakaki S., Atsumi T., and Sakurai H. Active oxygen scavenging activity of plant extracts. Biological & Pharmaceutical Bulletin 18 (1995) 162-166
31. Mensah A.Y., Hougthon P., Bloomfield S., Vlietnick A., and Van den Berghe D. Known and novel terpenes from Buddleja globosa displaying selective antifungal activity against dermatophytes. Journal of Natural Products 63 (2000) 1210-1213
32. Mensah A.Y., Sampson J., Houghton P.J., Hylands P.J., Westbrook J., Dunn M., Hughes M.A., and Cherry G.W. Effects of BuddIeja globosa leaf and its constituents relevant to wound healing. Journal of' Ethnopharmacology 77 (2001) 219-226
33. Middleton E.J.R., Kandaswami C., and Theoharides T.C. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Flavonoids as potential therapeutics agents. Pharmacological and Experimental Therapeutics 52 (2000) 673-751
34. Muñoz, M., Barrera, E., Meza, L., 1981. El Uso Medicinal y Alimenticio de Plantas Nativas y Naturalizadas en Chile, Museo Historia Natural, Public. Ocasional N° 33, p. 32.
35. Odontuya G., Hoult J.R.S., and Houghton P.J. Structure-activity relationship for anti-inflammatory effect of luteolin and its derived glycosides. Phytotherapy Research 19 (2005) 782-786
36. Otuki M.F., Ferreira J., Lima F.V., Meyre-Silva C., Malheiros A., Muller L.A., Cani G.S., Santos A.R.S., Yunes R.A., and Calixto J.B. Antinociceptive properties of mixture of α-amyrin and β-amyrin triterpenes: evidence for participation of protein kinase C and protein kinase A pathways. Journal of Pharmacology and Experimental Therapeutics 313 (2005) 310-318
37. Pereira J.A., Pereira A.P., Ferreira I.C., Valentão P., Andrade P.B., Reabra R., Estevinho L., and Bento A. Table olives from Portugal: phenolic compounds, antioxidant potential, and antimicrobial activity. Journal of Agriculture and Food Chemistry 54 (2006) 8425-8431
38. Recio M.C., Giner R.M., Máñez S., and Ríos J.L. Structural requirements for the anti-inflammatory activity of natural triterpenoids. Planta Medica 61 (1995) 182-185
39. Schapova l.E., Winter de Vargas M., Chaves C., Bridi R., Zuanazzi J., and Henriques A. Anti-inflammatory and antinociceptive activities of extracts and isolated compounds from Stachytarpheta cayennensis. Journal of Ethnopharmacology 60 (1998) 53-59
40. Schmeda-Hirschmann G., Rodríguez J.A., Theoduloz C., Astudillo S., Feresin G., and Tapia A. Free radical scavengers and antioxidants from Peumus boldus Mol. ("Boldo"). Free Radical Research 37 (2003) 447-452
41. Villaseñor I.M., Canias A.P., Faustino K.M., and Plana K.G. Evaluation of the bioactivity of triterpene mixture isolated from Carmona retusa (Vahl.) Masam leaves. Journal of Ethnopharmacology 92 (2004) 53-56
42. Villaseñor I.M., Angelada J., Canias A.P., and Echegoyen D. Bioactivity studies on beta-sitosterol and its glucoside. Phytotherapy Research 16 (2002) 417-421
43. Vogel H., Doll U., Razmilic I., and San Martín J. Domestication studies of matico (Buddleja globosa Hope). Acta Horticulturae 576 (2002) 203-206
44. 13C NMR data for phenylethanoid glycosides. Magnetic Resonance in Chemistry 42 (2004) 659-669