Preliminary pharmacological screening of Bixa orellana L. leaves

Journal of Ethnopharmacology

Volumn 108, Issue 2, 2006, Pages 264-271

  Shilpi, Jamil Ahmad ^a   Taufiq Ur Rahman, Md ^b   Uddin, Shaikh Jamal ^c   Alam, Md Shahanur ^c   Sadhu, Samir Kumar ^d   Seidel, Véronique ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c KHULNA UNIVERSITY   (Bangladesh)

^d CHIBA UNIVERSITY   (Japan)

Author keywords

Analgesic activity; Antibacterial activity; Antidiarrhoeal activity; Antioxidant activity; Bixa orellana; Charcoal motility test; Neuropharmacological activity

Indexed keywords

ACETIC ACID; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIDIARRHEALS; BIXACEAE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FREE RADICAL SCAVENGERS; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL TRANSIT; MALE; METHANOL; MICE; MOTOR ACTIVITY; PAIN; PLANT EXTRACTS; PLANT LEAVES; SEIZURES; STRYCHNINE;

ANIMALIA; BIXA ORELLANA; BIXACEAE; MUS; SHIGELLA DYSENTERIAE; STRYCHNOS TOXIFERA;

EID: 33750348126     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2006.05.008     Document Type: Article

References (46)

1. Abdullahi A.L., Agho M.O., Amos S., Gamaniel K.S., and Wambebe C. Antidiarrhoeal activity of the aqueous extract of Terminalia avicennoides roots. Phytotherapy Research 15 (2001) 431-434
2. Agner A.R., Bazo A.P., Ribeiro L.R., and Salvadori D.M. DNA damage and aberrant crypt foci as putative biomarkers to evaluate the chemopreventive effect of annatto (Bixa orellana L.) in rat colon carcinogenesis. Mutation Research 582 (2005) 146-154
3. Ammon H.V., Thomas P.J., and Phillips S. Effects of oleic and ricinoleic acids on net jejunal water and electrolyte movement. Perfusion studies in man. The Journal of Clinical Investigation 53 (1974) 374-379
4. Antunes L.M., Pascoal L.M., de L. Bianchi M., and Dias F.L. Evaluation of the clastogenicity and anticlastogenicity of the carotenoid bixin in human lymphocyte cultures. Mutation Research 585 (2005) 113-119
5. Barrio A.G., Grueiro M.M.M., Montero D., Nogal J.J., Escario J.A., Muelas S., Fernandez C., Vega C., Rolon M., Fernandez A.R.M., Solis P.N., and Gupta M.P. In vitro antiparasitic activity of plant extracts from Panama. Pharmaceutical Biology 42 (2004) 332-337
6. Bauer A.W., Kirby W.M.M., Sherris J.C., and Truck M. Antibiotic susceptibility testing by a standardised single disk method. The American Journal of Clinical Pathology 45 (1966) 493-496
7. Castello M.C., Phatak A., Chandra N., and Sharon M. Antimicrobial activity of crude extracts from plant parts and corresponding calli of Bixa orellana L. Indian Journal of Experimental Biology 40 (2002) 1378-1381
8. Collier H.O., Dinneen L.C., Johnson C.A., and Schneider C. The abdominal constriction response and its suppression by analgesic drugs in the mouse. British Journal of Pharmacology 32 (1968) 295-310
9. - current. The Journal of Neuroscience 13 (1993) 3211-3221
10. Fleischer T.C., Ameade E.P.K., Mensah M.L.K., and Sawer I.K. Antimicrobial activity of the leaves and seeds of Bixa orellana. Fitoterapia 74 (2003) 136-138
11. Frega N., Mozzon M., and Bocci F. Identification and estimation of tocotrienols in the annatto lipid fraction by gas chromatography mass spectrometry. Journal of the American Oil Chemists Society 75 (1998) 1723-1727
12. Fröhlich L., and Riederer P. Free radical mechanisms in dementia of Alzheimer type and the potential for antioxidant treatment. Arzneimittelforschung 45 (1995) 443-446
13. Galvez J., Zarzuelo A., Crespo M.E., Lorente M.D., Ocete M.A., and Jimenez J. Antidiarrhoeic activity of Euphorbia hirta extract and isolation of an active flavonoid constituent. Planta Medica 59 (1993) 333-336
14. Ghani A. Medicinal Plants of Bangladesh. second ed. (2003), Asiatic Society of Bangladesh, Dhaka p. 127
15. Gupta B.D., Dandiya P.C., and Gupta M.L. A psycho-pharmacological analysis of behaviour in rats. Japanese Journal of Pharmacology 21 (1971) 293-298
16. Gupta M., Mazumder U.K., and Chakrabarti S. CNS activities of methanolic extract of Moringa oleifera root in mice. Fitoterapia 70 (1999) 244-250
17. Harborne J.B. Flavonoid bisulfates and their co-occurrences with ellagic acid in the Bixaceae, Frankeniaceae, and related families. Phytochemistry 14 (1975) 1331-1337
18. Harborne J.B. Phytochemical Methods (A Guide to Modern Techniques to Plant Analysis). second ed. (1984), Chapman and Hall, London
19. l and prostanoids in the acid-induced writhing responses of mice. Life Sciences 69 (2001) 2911-2919
20. Irobi O.N., MooYoung M., and Anderson W.A. Antimicrobial activity of Annatto (Bixa orellana) extract. International Journal of Pharmacognosy 34 (1996) 87-90
21. Jondiko I.J.O., and Pattenden G. Terpenoids and an apocarotenoid from seeds of Bixa orellana. Phytochemistry 28 (1989) 3159-3162
22. Joshi S.G. Medicinal Plants (2000), Oxford and IBH Publishing Co., Pvt. Ltd., India p. 99
23. Junior A.C., Asad L.M., Oliveira E.B., Kovary K., Asad N.R., and Felzenszwalb I. Antigenotoxic and antimutagenic potential of an annatto pigment (norbixin) against oxidative stress. Genetics and Molecular Research 4 (2005) 94-99
24. Kirtikar K.R., and Basu B.D. Indian Medicinal Plants. second ed. (1999), International Book Distributors, India p. 217
25. Koster R., Anderson M., and DeBeer E.J. Acetic acid analgesic screening. Federation Proceedings 18 (1959) 418-420
26. Lawrence B.M., and Hogg J.W. Ishwarane in Bixa orellana leaf oil. Phytochemistry 12 (1973) 2995
27. Lorke D. A new approach to acute toxicity testing. Archives of Toxicology 54 (1983) 275-287
28. Mans D.R.A., Toelsie J.R., Jagernath Z., Ramjiawan K., van Brussel A., Jhanjan N., Orie S., Muringen M., Elliot U., Jurgens S., Macnack R., Rigters F., Mohan S., Chigharoe V., Illes S., and Bipat R. Assessment of eight popularly used plant-derived preparations for their spasmolytic potential using the isolated guinea pig ileum. Pharmaceutical Biology 42 (2004) 422-429
29. Martinez-Tome M., Jimenez A.M., Ruggieri S., Frega N., Strabbioli R., and Murcia M.A. Antioxidant properties of Mediterranean spices compared with common food additives. Journal of Food Protection 64 (2001) 1412-1419
30. McNamara J.O. Drugs effective in the therapy of the epilepsies. In: Hardman J.G., and Limbird L.E. (Eds). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 10th ed. (2001), McGraw Hill, New York, USA 521-547
31. Morrow J.D., Chen Y., Brame C.J., Yang J., Sanchez S.C., Xu J., Zackart W.E., Awad J.A., and Roberts L.J. The isoprostanes: unique prostaglandin-like products of free-radical-initiated lipid peroxidation. Drug Metabolism Reviews 31 (1999) 117-139
32. 2-like compounds are produced in-vivo in humans by a noncyclooxegenase, free radical-catalyzed mechanism. Proceedings of the National Academy of Sciences 87 (1990) 9383-9387
33. Murata T., Ushikubi F., Matsuoka T., Hirata M., Yamasaki A., Sugimoto Y., Ichikawa A., Aze Y., Tanaka T., Yoshida N., Ueno A., Oh-Ishi S., and Narumiya S. Altered pain perception and inflammatory response in mice lacking prostacyclin receptor. Nature 388 (1997) 678-682
34. Murray C.A., and Lynch M.A. Dietary supplementation with vitamin E reverses the age-related deficit in long term potentiation in dentate gyrus. The Journal of Biological Chemistry 273 (1998) 12161-12168
35. Nunez V., Otero R., Barona J., Saldarriaga M., Osorio R.G., Fonnegra R., Jimenez S.L., Diaz A., and Quintana J.C. Neutralization of the edema-forming, defibrinating and coagulant effects of Bothrops asper venom by extracts of plants used by healers in Colombia. Brazilian Journal of Medical and Biological Research 37 (2004) 969-977
36. Perry L.M. Medicinal Plants of East and Southeast Asia (1980), MIT Press, Cambridge, Massachusetts pp. 58-59
37. Perry N.S., Houghton P.J., Sampsom J., Theobald A.E., Hart S., Lis-Balchin M., Hoult J.R., Evans P., Jenner P., Milligan S., and Perry E.K. In vitro activity of S. lavandulaefolia (Spanish sage) relevant to treatment of Alzheimer's disease. Journal of Pharmacy and Pharmacology 53 (2001) 1347-1356
38. Pino J.A., and Correa M.T. Chemical composition of the essential oil from annatto (Bixa orellana L.) seeds. Journal of Essential Oil Research 15 (2003) 66-67
39. Ramirez N.N., Ruiz J.D.Q., Arellano B.R., Madrigal M.T.V., and Michel G.P. Anticonvulsant effects of Magnolia grandifora L. in the rats. Journal of Ethnopharmacology 61 (1998) 143-152
40. Satyanarayana A., Rao P.G.P., and Rao D.G. Chemistry, processing and toxicology of annatto (Bixa orellana L.). Journal of Food Science and Technology-Mysore 40 (2003) 131-141
41. Schneider W.P., Caron E.L., and Hinman J.W. Occurrence of tomentosic acid in extracts of Bixa orellana. Journal of Organic Chemistry 30 (1965) 2856-2857
42. Takagi K., Watanabe M., and Saito H. Studies on the spontaneous movement of animals by the hole cross test: effect of 2-dimethyl-aminoethanol and its acyl esters on the central nervous system. Japanese Journal of Pharmacology 21 (1971) 797-810
43. Villar R., Calleja J.M., Morales C., and Caceres A. Screening of 17 Guatemalan medicinal plants for platelet antiaggregant activity. Phytotherapy Research 11 (1997) 441-445
44. Xiong Q., Kadota S., Tani T., and Namba T. Antioxidative effects of phenylethanoids from Cistanche deserticola. Biological and Pharmaceutical Bulletin 19 (1996) 1580-1585
45. Yan X., Nagata T., and Fa X. Antioxidative activities in some common seaweeds. Plant Foods for Human Nutrition 52 (1998) 253-262
46. Yusuf M., Chowdhury J.U., Yahab M.A., and Begum J. Medicinal Plants of Bangladesh (1994), BCSIR Laboratories, Bangladesh p. 38