Control of electrochemical and ferryloxy formation kinetics of cyt P450s in polyion films by heme iron spin state and secondary structure

Journal of the American Chemical Society

Volumn 131, Issue 44, 2009, Pages 16215-16224

  Krishnan, Sadagopan ^a   Abeykoon, Amila ^a   Schenkman, John B ^b   Rusling, James F ^a,b,c  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^c NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ASYMMETRIC REDUCTION; CONFORMATIONAL EQUILIBRIUM; CYTOCHROME P450; FORMATION KINETICS; HEME IRON; HETEROGENEOUS ELECTRON TRANSFER; HIGH SPINS; MIXED SPINS; OXIDATION AND REDUCTION; POLYION FILMS; POLYIONS; PROTEIN SECONDARY STRUCTURE; REDUCTION RATE; REVERSE ORDER; ROTATING DISK VOLTAMMETRY; SCAN RATES; SECONDARY STRUCTURES; SPIN STATE; T-BUTYL HYDROPEROXIDE;

ELECTRON TRANSITIONS; HEMOGLOBIN; OXIDATION; PORPHYRINS; RATE CONSTANTS; REDUCTION; ROTATING DISKS; ULTRATHIN FILMS; VOLTAMMETRY;

SPIN DYNAMICS;

BUTYL HYDROPEROXIDE; CYTOCHROME P450 1A2; CYTOCHROME P450 2E1; HEME; IRON;

ARTICLE; CONTROLLED STUDY; ELECTRON TRANSPORT; FILM; HUMAN; KINETICS; POTENTIOMETRY; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE;

CYTOCHROME P-450 ENZYME SYSTEM; ELECTROCHEMICAL TECHNIQUES; ELECTRON TRANSPORT; HEME; HUMANS; IRON; KINETICS; MOLECULAR STRUCTURE; PROTEIN STRUCTURE, SECONDARY;

EID: 70450171013     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9065317     Document Type: Article

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