Preliminary electrochemical characterisation of cytochrome P4501A2-clozapine interaction

IEE Proceedings Nanobiotechnology

Volumn 150, Issue 1, 2003, Pages 31-34

  Antonini, M ^a   Ghisellini, P ^a   Pastorino, L ^a   Paternolli, C ^a   Nicolini, C ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSENSORS; BLOOD; DRUG PRODUCTS; ENZYMES; FATTY ACIDS; METABOLISM; METABOLITES; PHARMACOKINETICS; TOXIC MATERIALS;

CHRONOAMPEROMETRY; CLOZAPINE; CYTOCHROME; ORGANIC SUBSTRATES;

ELECTROCHEMISTRY;

EID: 1242311598     PISSN: 14781581     EISSN: None     Source Type: Journal    
DOI: 10.1049/ip-nbt:20030534     Document Type: Conference Paper

References (43)

1. OMURA, T., ISHIMURA, Y. and FUYII-KURIYAMA, Y. (Eds.): 'Molecular properties and reaction mechanisms in cytochrome P450' (Kodansha, Tokyo, Japan, 1993, 2nd edn.)
2. PARKE, D.C., IOANNIDES, C.C., and LEVIS, D.F.: 'The role of the cytochrome P450 in the detoxification and activation of drugs and other chemicals', Can. J. Physiol. Pharm, 1991, 89, pp. 537-547
3. BRØSEN, K.: 'Drug-metabolizing enzymes and therapeutic drug monitoring in psychiatry', Ther. Drug Monit., 1996, 18, pp. 393-396
4. CARILLO, J.A., DAHL, M.L., SVENSSON, J.O., ALM, C., RODRIGUEZ, I., and BERTILSSON, L.: 'Disposition of fluvoxamine in humans is determined by the polymorphic CYP2D6 and also by CYP1A2 activity', Clin. Pharmacol. Ther., 1996, 60, pp. 183-190
5. BUTLER, M.A., IWAZAKI, F.P., and GUENGERICH, F.P.: 'Human cytochrome P-459PA (P4501A2), the phenacetic O-deethylase, is primarily responsible for the hematic 3-demethylation of caffeine and N-oxydation of carcinogenic arylamines', Proc. Natl. Acad Sci. USA, 1989, 86, pp. 7696-7710
6. ROBSON, R.A., MATTHEWS, A.P., and MINERS, J.O.: 'Characterisation of theophylline metabolism in human liver microsomes', Br. J. Clin. Pharmacol., 1987, 24, pp. 293-301
7. VINCENT, P.C.: 'Drug-induced aplastic anaemia and agranulocytosis: incidence and mechanisms', Drugs, 1986, 31, pp. 52-63
8. JUUL, P.U., NORING, U., and FOG, R.: Tolerability and therapeutic effect of clozapine: A retrospective investigation of 216 patients treated with clozapine for up to 12 years', Acta Psychiatr. Scand., 1985, 71, pp. 176-185
9. FREEMAN, D.J., and OYEWUMI, L.K.: 'Will routine therapeutic drug monitoring have a place in clozapine therapy?', Clin. Pharmacokinet., 1997, 32, pp. 93-100
10. DOLLO, G., BUN, H., and BONNEFONT-CORNET, M.: 'Determination of clozapine by HPLC and drug monitoring applications', J. Clin. Pharmacol., 1994, 13, pp. 17-22
11. JANN, N.W., GRIMSLEY, S.R., GRAY; E.C., and CHANG, W.H.: 'Pharmacokinetics and pharmadynamics of clozapine', Clin. Pharmacokinet., 1993, 24, pp. 161-176
12. LIU, H.C., CHANG, W.H., WEI, F.C., LIN, S.K., LIN, S.K., and JANN, M.W.: 'Monitoring of plasma clozapine levels and its metabolites in refractory schizophrenic patients', Ther. Drug Monit., 1996, 18, pp. 200-207
13. LOVDHAL, M.J., PERRY, P.J., and MILLER, D.D.: 'The assay of clozapine and N-desmetylclozapine in human plasma by high performance liquid chromatography", Ther. Drug Monit., 1991, 13, pp. 69-72
14. VOLPICELLI, S.A., CENTORRINO, F., PUOPOLO, P.R., KANDO, Y., FRANKENBURG, F.R., BALDESSARINI, R.J., and FLOOD, J.G.: 'Determination of clozapine, norclozapine and clozapine-N-oxide in serum by liquid chromatography', Clin. Chem., 1993, 39, pp. 1656-1959
15. ZEREN, W., MINGLIAN, L., and PEIPEI, X.: 'Determination of clozapine and its metabolities in serum and urine by reserved phase HPLC', Biomed. Chromatogr., 1987, 1, pp. 53-57
16. OMURA, T., and SATO, R.: 'The carbon monoxide binding pigment of liver microsomes. II. Solubilization, purification and properties', J. Biol. Chem., 1964, 239, pp. 2379-2385
17. ERESHEFSKY, L.: 'Pharmacokinetics and drug interactions: update for new antipsychotics', J. Clin. Psychiatry, 1996, 57, (Suppl. 11), pp. 10-19
18. BYERLY, M.J., and DEVANE, C.L.: 'Pharmacokinetics of clozapine and risperidone: a review of recent literature', J. Clin. Psychopharmacol., 1996, 16, pp. 177-187
19. OZDEMIR, V., KALOW, W., POSNER, P., COLLINS, E.J., KENNEDY, J.L., and TANG, B.K.: 'CYP1A2 activity as measured by a caffeine test predicts clozapine and active metabolite steady-state concentration in patients with schizophrenia', J. Clin. Psychopharmacol., 2001, 21, pp. 398-407
20. LINNET, K., and OLESEN, O.V.: 'Metabolism of clozapine by cDNA-expressed human cytochrome P450 enzymes', Drug Metab. Dispos., 1997, 25, pp. 1379-1382
21. ACKENHEIL, M.: 'Clozapine-pharmacokinetic investigation and biochemical in man', Psychophamacol Bull., 1989, 99S, pp. S32-537
22. PIRMOHAMED, M., WILLIAMS, D., MADDEN, S., TEMPLETON, E., and PARK, B.K.: 'Metabolism and bioactivation of clozapine by human liver in vitro', J. Pharmacol. Exp. Therap., 1995, 272, (3), pp. 984-989
23. BERTILSSON, L., CARRILLO, J.A., DAHL, M.L., LLERENA, A., ALM, C., BONDESSON, U., LINDSTROM, L., RODRIGUEZ DE LA RUBIA, I., RAMOS, S., and BENITEZ, J.: 'Clozapine deposition covaries with CYP1A2 activity determined by a caffeine test', Br. J. Clin. Phamacol., 1994, 38, (5), pp. 471-473
24. THORUP, M., and FOG, R.F.: 'Clozapine treatment of schizophrenic patients: Plasma concentration and coagulation factors', Acta Psychiatr. Scand., 1977, 55, pp. 123-130
25. DAILLY, E., URIEN, S., CHANUT, E., CLAUDEL, B., GUERRA, N., FERNANDEZ, C., JOLLIET, P., and BOURIN, M.: 'Evidence from a population pharmacokinetics analysis for a major effect of CYP1A2 activity on inter- and intraindividual variations of clozapine clearance', Prog. Neuro Psychopharmacol Biol. Psychiatry, 2002, 26, pp. 699-703
26. KULYS, J., and D'COSTA, E.J.: 'Printed amperometric sensor based on TCNQ and cholinesterase', Biosensors Bioelectron., 1991, 6, pp. 109-115
27. BACHMANN, T.T., and SCHMID, R.D.: 'A disposable multi-electrode biosensor for rapid simultaneous detection of the insecticides paraoxon and carbofuran at high resolution', Anal. Chim. Acta, 1999, 401, pp. 95-106
28. O'CONNELL, P.J., O'SULLIVAN, C.K., and GUILBAULT, G.G.: 'Electrochemical metallisation of carbon electrodes', Anal. Chim. Acta, 1998, 373, pp. 261-270
29. KRÖGER, S., and TURNER, A.P.F.: 'Solvent-resistant carbon electrodes screen printed onto plastic for use in biosensors', Anal. Chim. Acta., 1997, 347, pp. 9-18
30. DOLPHIN, D., AVRAMOVIC, O. and POULSON, R. (Eds.): 'Pyridine nucleotide coenzymes (coenzymes and cofactors)' (Wiley, New York, 1987), Vol. 2, (pts A and B)
31. PATEL, A.B., and PHADKE, R.S.: 'Synthesis, characterization and film formation of modified riboflavin', Mater. Sci Eng. C, 1995, 3, pp. 273-276
32. GHISLA, S., and MASSEY, V.: 'Mechanisms of flavoprotein-catalyzed reactions', Eur. J. Biochem., 1991, 181, pp. 1-17
33. MALINAUSKAS, A., RUZGAS, T., and GORTON, L.: 'Tuning the redox potential of riboflavin by zirconium phosphate in carbon paste electrodes', Bioelectrochem. Bioenergetics, 1999, 49, pp. 21-27
34. SHUMYANTSEVA, V.V., BULKO, T.V., USANOV, S.A., SCHMID, R.D., NICOLINI, C., and ARCHAKOV, A.I.: 'Construction and characterization of bioelectrocatalytic sensors based on cytochromes P450", J. Inorg. Biochem., 2001, 87, pp. 185-190
35. ARCHAKOV, A.I., and BACHMANOVA, G.I.: 'Cytochrome P450 and active oxygen" (Taylor and Francis, London, 1990)
36. HARA, M.: 'Application of P450s for biosensing: combination of biotechnology and electrochemistry', Mater, Sci. Eng. C, 2000, 12, pp. 103-109
37. VIRÉ, J.C., KAUFFMAN, J.M., and PATRIARCHE, G.J.: 'Etude electrochimique d'un nouveau neuroleptique: la loxapine', Anal Lett., 1982, 15, (B16), pp. 1331-1343
38. KAUFFMAN, J.M., LAUDET, A., VIRÉ, J.C., PATRIARCHE, G.J., and CHRISTIAN, G.D.: 'Voltammetry oxidation of pharmaceutical organic compounds at a new modified electrode: the aluminium graphite spray-covered electrodes', Microchem. J., 1983, 28, pp. 357-362
39. JARBAWI, T.B., and HEINEMAN, W.R.: 'Preconcentration of tranquilizers by adsorption/extraction at a wax-impregnated graphite electrode', Anal. Chim. Acta., 1986, 186, pp. 11-19
40. HERNÁNDEZ, L., GONZÁLES, E., and HERNÁNDEZ, P.: 'Determination of clozapine by adsorptive anodic voltammetry using glassy carbon and modified carbon paste electrodes', Analyst, 1988, 113, pp. 1715-1718
41. HARING, C., BARNAS, C., SARIA, A., HUMPEL, C., and FLEISCHACKER, W.W.: 'Dose-related plasma levels of clozapine: influence of smoking of behaviour, sex and age', J. Clin. Psychopharmacol., 1989, 9, pp. 71-80
42. RAHDEN-STARON, I., CZECZOT, H., and SZUMILO, M.: 'Induction of rat liver cytochrome P450 isoenzymes CYP 1A and CYP 2B by different fungicides, nitrofurans, and quercetin", Mutation Res., 2001, 1, pp. 1-10
43. BUUR-RASMUSSEN, B., and BRØSEN, K.: 'Cytochrome P450 and therapeutic drug monitoring with respect to clozapine', Eur. Neuropsychopharmacol., 1999, 9, pp. 453-459