Electrochemiluminescent arrays for cytochrome P450-activated genotoxicity screening. DNA damage from benzo[a]pyrene metabolites

Analytical Chemistry

Volumn 79, Issue 5, 2007, Pages 1897-1906

  Hvastkovs, Eli G ^a   So, Minjeong ^a   Krishnan, Sadagopan ^a   Bajrami, Besnik ^a   Tarun, Maricar ^a   Jansson, Ingela ^b   Schenkman, John B ^b   Rusling, James F ^a,b  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMILUMINESCENCE; DNA; ELECTROLUMINESCENCE; ENZYMES; METABOLITES; ORGANIC POLYMERS; THIN FILMS;

DNA DAMAGE; ELECTROCHEMILUMINESCENCE (ECL); GENOTOXICITY SCREENING; METALLOPOLYMERS; MYOGLOBIN;

MICROARRAYS;

BENZO[A]PYRENE; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 2E1; HYDROGEN PEROXIDE; MYOGLOBIN; POLYMER; RUTHENIUM DERIVATIVE;

ARTICLE; CAMERA; CHEMOLUMINESCENCE; DNA DAMAGE; ELECTROCHEMICAL ANALYSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; EXPOSURE; FILM; GENOTOXICITY; HIGH THROUGHPUT SCREENING; METABOLITE;

BENZO(A)PYRENE; CARCINOGENS; CHEMILUMINESCENT MEASUREMENTS; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DNA; DNA DAMAGE; ELECTROCHEMISTRY; EPOXY COMPOUNDS; HUMANS; HYDROGEN PEROXIDE; MASS SPECTROMETRY; MICROARRAY ANALYSIS; ORGANOMETALLIC COMPOUNDS; REPRODUCIBILITY OF RESULTS;

EID: 33847644556     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac061975q     Document Type: Article

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