메뉴 건너뛰기




Volumn 187, Issue 2, 2009, Pages 265-277

Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NBR1 PROTEIN; SPRED2 PROTEIN; SPROUTY PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; NBR1 PROTEIN, HUMAN; NBR1 PROTEIN, MOUSE; PROTEIN; REPRESSOR PROTEIN; SPRED2 PROTEIN, HUMAN; SPRED2 PROTEIN, MOUSE;

EID: 70449728467     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200905118     Document Type: Article
Times cited : (43)

References (47)
  • 1
    • 46249129455 scopus 로고    scopus 로고
    • Extracellular point mutations in FGFR2 elicit unexpected changes in intracellular signalling
    • doi:10.1042/BJ20071594
    • Ahmed, Z., A.C. Schüller, K. Suhling, C. Tregidgo, and J.E. Ladbury. 2008. Extracellular point mutations in FGFR2 elicit unexpected changes in intracellular signalling. Biochem. J. 413:37-49. doi:10.1042/BJ20071594
    • (2008) Biochem. J , vol.413 , pp. 37-49
    • Ahmed, Z.1    Schüller, A.C.2    Suhling, K.3    Tregidgo, C.4    Ladbury, J.E.5
  • 2
    • 0037138362 scopus 로고    scopus 로고
    • EVH1 domains: Structure, function and interactions
    • doi:10.1016/S0014-5793(01)03291-4
    • Ball, L.J., T. Jarchau, H. Oschkinat, and U. Walter. 2002. EVH1 domains: structure, function and interactions. FEBS Lett. 513:45-52. doi:10.1016/S0014-5793(01)03291-4
    • (2002) FEBS Lett , vol.513 , pp. 45-52
    • Ball, L.J.1    Jarchau, T.2    Oschkinat, H.3    Walter, U.4
  • 3
    • 33845764296 scopus 로고    scopus 로고
    • A guided tour into subcellular colocalization analysis in light microscopy
    • doi:10.1111/j.1365-2818.2006.01706.x
    • Bolte, S., and F.P. Cordelières. 2006. A guided tour into subcellular colocalization analysis in light microscopy. J. Microsc. 224:213-232. doi:10.1111/j.1365-2818.2006.01706.x
    • (2006) J. Microsc , vol.224 , pp. 213-232
    • Bolte, S.1    Cordelières, F.P.2
  • 5
    • 32944477229 scopus 로고    scopus 로고
    • Tissue-specific Spred-2 promoter activity characterized by a gene trap approach
    • doi:10.1016/j.modgep.2005. 08.003
    • Bundschu, K., S. Gattenlöhner, K.P. Knobeloch, U. Walter, and K. Schuh. 2006. Tissue-specific Spred-2 promoter activity characterized by a gene trap approach. Gene Expr. Patterns. 6:247-255. doi:10.1016/j.modgep.2005. 08.003
    • (2006) Gene Expr. Patterns , vol.6 , pp. 247-255
    • Bundschu, K.1    Gattenlöhner, S.2    Knobeloch, K.P.3    Walter, U.4    Schuh, K.5
  • 6
    • 0033525895 scopus 로고    scopus 로고
    • Sprouty, an intracellular inhibitor of Ras signaling
    • doi:10.1016/S0092-8674(00)80576-0
    • Casci, T., J. Vinós, and M. Freeman. 1999. Sprouty, an intracellular inhibitor of Ras signaling. Cell. 96:655-665. doi:10.1016/S0092-8674(00)80576-0
    • (1999) Cell , vol.96 , pp. 655-665
    • Casci, T.1    Vinós, J.2    Freeman, M.3
  • 8
    • 26944484011 scopus 로고    scopus 로고
    • Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling
    • doi:10.1016/j.molcel.2005.09.014
    • Geetha, T., J. Jiang, and M.W. Wooten. 2005. Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling. Mol. Cell. 20:301-312. doi:10.1016/j.molcel.2005.09.014
    • (2005) Mol. Cell , vol.20 , pp. 301-312
    • Geetha, T.1    Jiang, J.2    Wooten, M.W.3
  • 9
    • 0032559228 scopus 로고    scopus 로고
    • sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways
    • doi:10.1016/S0092-8674(00)80919-8
    • Hacohen, N., S. Kramer, D. Sutherland, Y. Hiromi, and M.A. Krasnow. 1998. sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. Cell. 92:253-263. doi:10.1016/S0092-8674(00)80919-8
    • (1998) Cell , vol.92 , pp. 253-263
    • Hacohen, N.1    Kramer, S.2    Sutherland, D.3    Hiromi, Y.4    Krasnow, M.A.5
  • 10
    • 0036847930 scopus 로고    scopus 로고
    • Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway
    • doi:10.1038/ncb867
    • Hanafusa, H., S. Torii, T. Yasunaga, and E. Nishida. 2002. Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway. Nat. Cell Biol. 4:850-858. doi:10.1038/ncb867
    • (2002) Nat. Cell Biol , vol.4 , pp. 850-858
    • Hanafusa, H.1    Torii, S.2    Yasunaga, T.3    Nishida, E.4
  • 11
    • 13844261181 scopus 로고    scopus 로고
    • 1.15 A crystal structure of the X. tropicalis Spred1 EVH1 domain suggests a fourth distinct peptide-binding mechanism within the EVH1 family
    • doi:10.1016/j.febslet.2004.11.114
    • Harmer, N.J., J.M. Sivak, E. Amaya, and T.L. Blundell. 2005. 1.15 A crystal structure of the X. tropicalis Spred1 EVH1 domain suggests a fourth distinct peptide-binding mechanism within the EVH1 family. FEBS Lett. 579:1161-1166. doi:10.1016/j.febslet.2004.11.114
    • (2005) FEBS Lett , vol.579 , pp. 1161-1166
    • Harmer, N.J.1    Sivak, J.M.2    Amaya, E.3    Blundell, T.L.4
  • 12
    • 0035809919 scopus 로고    scopus 로고
    • Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells
    • doi:10.1083/jcb.152.5.1087
    • Impagnatiello, M.A., S. Weitzer, G. Gannon, A. Compagni, M. Cotten, and G. Christofori. 2001. Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells. J. Cell Biol. 152:1087-1098. doi:10.1083/jcb.152.5.1087
    • (2001) J. Cell Biol , vol.152 , pp. 1087-1098
    • Impagnatiello, M.A.1    Weitzer, S.2    Gannon, G.3    Compagni, A.4    Cotten, M.5    Christofori, G.6
  • 14
    • 0037459180 scopus 로고    scopus 로고
    • Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation
    • doi:10.1016/S0006-291X(03)00259-6
    • Kato, R., A. Nonami, T. Taketomi, T. Wakioka, A. Kuroiwa, Y. Matsuda, and A. Yoshimura. 2003. Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation. Biochem. Biophys. Res. Commun. 302:767-772. doi:10.1016/S0006-291X(03)00259-6
    • (2003) Biochem. Biophys. Res. Commun , vol.302 , pp. 767-772
    • Kato, R.1    Nonami, A.2    Taketomi, T.3    Wakioka, T.4    Kuroiwa, A.5    Matsuda, Y.6    Yoshimura, A.7
  • 15
    • 33847260172 scopus 로고    scopus 로고
    • Spatial regulation of EGFR signaling by Sprouty2
    • doi:10.1016/j.cub.2007. 01.059
    • Kim, H.J., L.J. Taylor, and D. Bar-Sagi. 2007. Spatial regulation of EGFR signaling by Sprouty2. Curr. Biol. 17:455-461. doi:10.1016/j.cub.2007. 01.059
    • (2007) Curr. Biol , vol.17 , pp. 455-461
    • Kim, H.J.1    Taylor, L.J.2    Bar-Sagi, D.3
  • 17
    • 33847705665 scopus 로고    scopus 로고
    • Role of ubiquitin- and Ubl-binding proteins in cell signaling
    • doi:10.1016/j.ceb.2007.02.002
    • Kirkin, V., and I. Dikic. 2007. Role of ubiquitin- and Ubl-binding proteins in cell signaling. Curr. Opin. Cell Biol. 19:199-205. doi:10.1016/j.ceb.2007.02.002
    • (2007) Curr. Opin. Cell Biol , vol.19 , pp. 199-205
    • Kirkin, V.1    Dikic, I.2
  • 19
    • 0033035109 scopus 로고    scopus 로고
    • Sprouty: A common antagonist of FGF and EGF signaling pathways in Drosophila
    • Kramer, S., M. Okabe, N. Hacohen, M.A. Krasnow, and Y. Hiromi. 1999. Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila. Development. 126:2515-2525.
    • (1999) Development , vol.126 , pp. 2515-2525
    • Kramer, S.1    Okabe, M.2    Hacohen, N.3    Krasnow, M.A.4    Hiromi, Y.5
  • 20
    • 0033544953 scopus 로고    scopus 로고
    • Dynamin is required for the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase
    • doi:10.1074/jbc.274.50.35301
    • Kranenburg, O., I. Verlaan, and W.H. Moolenaar. 1999. Dynamin is required for the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase. J. Biol. Chem. 274:35301-35304. doi:10.1074/jbc.274.50.35301
    • (1999) J. Biol. Chem , vol.274 , pp. 35301-35304
    • Kranenburg, O.1    Verlaan, I.2    Moolenaar, W.H.3
  • 22
    • 0037154885 scopus 로고    scopus 로고
    • Retrograde support of neuronal survival without retrograde transport of nerve growth factor
    • doi:10.1126/science.1064913
    • MacInnis, B.L., and R.B. Campenot. 2002. Retrograde support of neuronal survival without retrograde transport of nerve growth factor. Science. 295:1536-1539. doi:10.1126/science.1064913
    • (2002) Science , vol.295 , pp. 1536-1539
    • MacInnis, B.L.1    Campenot, R.B.2
  • 23
    • 3142592401 scopus 로고    scopus 로고
    • Not just a sink: Endosomes in control of signal transduction
    • doi:10.1016/j.ceb.2004.06.005
    • Miaczynska, M., L. Pelkmans, and M. Zerial. 2004. Not just a sink: endosomes in control of signal transduction. Curr. Opin. Cell Biol. 16:400-406. doi:10.1016/j.ceb.2004.06.005
    • (2004) Curr. Opin. Cell Biol , vol.16 , pp. 400-406
    • Miaczynska, M.1    Pelkmans, L.2    Zerial, M.3
  • 24
  • 25
    • 1542283696 scopus 로고    scopus 로고
    • Spred-2 suppresses aorta-gonad-mesonephros hematopoiesis by inhibiting MAP kinase activation
    • doi:10.1084/jem.20030830
    • Nobuhisa, I., R. Kato, H. Inoue, M. Takizawa, K. Okita, A. Yoshimura, and T. Taga. 2004. Spred-2 suppresses aorta-gonad-mesonephros hematopoiesis by inhibiting MAP kinase activation. J. Exp. Med. 199:737-742. doi:10.1084/jem.20030830
    • (2004) J. Exp. Med , vol.199 , pp. 737-742
    • Nobuhisa, I.1    Kato, R.2    Inoue, H.3    Takizawa, M.4    Okita, K.5    Yoshimura, A.6    Taga, T.7
  • 26
    • 10644259435 scopus 로고    scopus 로고
    • Spred-1 negatively regulates interleukin-3-mediated ERK/mitogen-activated protein (MAP) kinase activation in hematopoietic cells
    • doi:10.1074/jbc. M405189200
    • Nonami, A., R. Kato, K. Taniguchi, D. Yoshiga, T. Taketomi, S. Fukuyama, M. Harada, A. Sasaki, and A. Yoshimura. 2004. Spred-1 negatively regulates interleukin-3-mediated ERK/mitogen-activated protein (MAP) kinase activation in hematopoietic cells. J. Biol. Chem. 279:52543-52551. doi:10.1074/jbc. M405189200
    • (2004) J. Biol. Chem , vol.279 , pp. 52543-52551
    • Nonami, A.1    Kato, R.2    Taniguchi, K.3    Yoshiga, D.4    Taketomi, T.5    Fukuyama, S.6    Harada, M.7    Sasaki, A.8    Yoshimura, A.9
  • 27
    • 0037450766 scopus 로고    scopus 로고
    • Mechanism of the spatiotemporal regulation of Ras and Rap1
    • doi:10.1093/emboj/cdg087
    • Ohba, Y., K. Kurokawa, and M. Matsuda. 2003. Mechanism of the spatiotemporal regulation of Ras and Rap1. EMBO J. 22:859-869. doi:10.1093/emboj/cdg087
    • (2003) EMBO J , vol.22 , pp. 859-869
    • Ohba, Y.1    Kurokawa, K.2    Matsuda, M.3
  • 28
    • 0033974109 scopus 로고    scopus 로고
    • FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors
    • doi:10.1128/MCB.20.3.979-989.2000
    • Ong, S.H., G.R. Guy, Y.R. Hadari, S. Laks, N. Gotoh, J. Schlessinger, and I. Lax. 2000. FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors. Mol. Cell. Biol. 20:979-989. doi:10.1128/MCB.20.3.979-989.2000
    • (2000) Mol. Cell. Biol , vol.20 , pp. 979-989
    • Ong, S.H.1    Guy, G.R.2    Hadari, Y.R.3    Laks, S.4    Gotoh, N.5    Schlessinger, J.6    Lax, I.7
  • 29
    • 34548259958 scopus 로고    scopus 로고
    • p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    • doi:10.1074/jbc.M702824200
    • Pankiv, S., T.H. Clausen, T. Lamark, A. Brech, J.A. Bruun, H. Outzen, A. ∅vervatn, G. Bjørkøy, and T. Johansen. 2007. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J. Biol. Chem. 282:24131-24145. doi:10.1074/jbc.M702824200
    • (2007) J. Biol. Chem , vol.282 , pp. 24131-24145
    • Pankiv, S.1    Clausen, T.H.2    Lamark, T.3    Brech, A.4    Bruun, J.A.5    Outzen, H.6    ∅vervatn, A.7    Bjørkøy, G.8    Johansen, T.9
  • 30
    • 33644769212 scopus 로고    scopus 로고
    • Endocytosis conducts the cell signaling orchestra
    • doi:10.1016/j.cell.2006.02.025
    • Polo, S., and P.P. Di Fiore. 2006. Endocytosis conducts the cell signaling orchestra. Cell. 124:897-900. doi:10.1016/j.cell.2006.02.025
    • (2006) Cell , vol.124 , pp. 897-900
    • Polo, S.1    Di Fiore, P.P.2
  • 31
    • 0032841608 scopus 로고    scopus 로고
    • Sprouty is a general inhibitor of receptor tyrosine kinase signaling
    • Reich, A., A. Sapir, and B. Shilo. 1999. Sprouty is a general inhibitor of receptor tyrosine kinase signaling. Development. 126:4139-4147.
    • (1999) Development , vol.126 , pp. 4139-4147
    • Reich, A.1    Sapir, A.2    Shilo, B.3
  • 32
    • 0242684548 scopus 로고    scopus 로고
    • Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops
    • doi:10.1016/S0960-9822(03)00053- 8
    • Rubin, C., V. Litvak, H. Medvedovsky, Y. Zwang, S. Lev, and Y. Yarden. 2003. Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops. Curr. Biol. 13:297-307. doi:10.1016/S0960-9822(03)00053- 8
    • (2003) Curr. Biol , vol.13 , pp. 297-307
    • Rubin, C.1    Litvak, V.2    Medvedovsky, H.3    Zwang, Y.4    Lev, S.5    Yarden, Y.6
  • 33
    • 0031946369 scopus 로고    scopus 로고
    • Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62
    • Sanchez, P., G. De Carcer, I.V. Sandoval, J. Moscat, and M.T. Diaz-Meco. 1998. Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62. Mol. Cell. Biol. 18:3069-3080.
    • (1998) Mol. Cell. Biol , vol.18 , pp. 3069-3080
    • Sanchez, P.1    De Carcer, G.2    Sandoval, I.V.3    Moscat, J.4    Diaz-Meco, M.T.5
  • 34
    • 36748999354 scopus 로고    scopus 로고
    • Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors
    • 8:1162-1169. doi:10.1038/sj.embor.7401097
    • Sandilands, E., S. Akbarzadeh, A. Vecchione, D.G. McEwan, M.C. Frame, and J.K. Heath. 2007. Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors. EMBO Rep. 8:1162-1169. doi:10.1038/sj.embor.7401097
    • (2007) EMBO Rep
    • Sandilands, E.1    Akbarzadeh, S.2    Vecchione, A.3    McEwan, D.G.4    Frame, M.C.5    Heath, J.K.6
  • 35
    • 48549088895 scopus 로고    scopus 로고
    • Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation
    • doi:10.1016/j.devcel.2008.06.012
    • Sigismund, S., E. Argenzio, D. Tosoni, E. Cavallaro, S. Polo, and P.P. Di Fiore. 2008. Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation. Dev. Cell. 15:209-219. doi:10.1016/j.devcel.2008.06.012
    • (2008) Dev. Cell , vol.15 , pp. 209-219
    • Sigismund, S.1    Argenzio, E.2    Tosoni, D.3    Cavallaro, E.4    Polo, S.5    Di Fiore, P.P.6
  • 36
    • 17844381597 scopus 로고    scopus 로고
    • FGF signal interpretation is directed by Sprouty and Spred proteins during mesoderm formation
    • doi:10.1016/j.devcel.2005.02.011
    • Sivak, J.M., L.F. Petersen, and E. Amaya. 2005. FGF signal interpretation is directed by Sprouty and Spred proteins during mesoderm formation. Dev. Cell. 8:689-701. doi:10.1016/j.devcel.2005.02.011
    • (2005) Dev. Cell , vol.8 , pp. 689-701
    • Sivak, J.M.1    Petersen, L.F.2    Amaya, E.3
  • 37
    • 51549119338 scopus 로고    scopus 로고
    • Targeted online liquid chromatography electron capture dissociation mass spectrometry for the localization of sites of in vivo phosphorylation in human Sprouty2
    • doi:10.1021/ac800963a
    • Sweet, S.M., F.K. Mardakheh, K.J. Ryan, A.J. Langton, J.K. Heath, and H.J. Cooper. 2008. Targeted online liquid chromatography electron capture dissociation mass spectrometry for the localization of sites of in vivo phosphorylation in human Sprouty2. Anal. Chem. 80:6650-6657. doi:10.1021/ac800963a
    • (2008) Anal. Chem , vol.80 , pp. 6650-6657
    • Sweet, S.M.1    Mardakheh, F.K.2    Ryan, K.J.3    Langton, A.J.4    Heath, J.K.5    Cooper, H.J.6
  • 38
    • 0036899420 scopus 로고    scopus 로고
    • Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction
    • doi:10.1016/S1534-5807(02) 00364-7
    • Teis, D., W. Wunderlich, and L.A. Huber. 2002. Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction. Dev. Cell. 3:803-814. doi:10.1016/S1534-5807(02) 00364-7
    • (2002) Dev. Cell , vol.3 , pp. 803-814
    • Teis, D.1    Wunderlich, W.2    Huber, L.A.3
  • 40
    • 0030461226 scopus 로고    scopus 로고
    • Control of EGF receptor signaling by clathrin-mediated endocytosis
    • doi:10.1126/science.274.5295.2086
    • Vieira, A.V., C. Lamaze, and S.L. Schmid. 1996. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science. 274:2086-2089. doi:10.1126/science.274.5295.2086
    • (1996) Science , vol.274 , pp. 2086-2089
    • Vieira, A.V.1    Lamaze, C.2    Schmid, S.L.3
  • 41
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • doi:10.1038/nm1087
    • Vogelstein, B., and K.W. Kinzler. 2004. Cancer genes and the pathways they control. Nat. Med. 10:789-799. doi:10.1038/nm1087
    • (2004) Nat. Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 43
    • 67349216078 scopus 로고    scopus 로고
    • Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover
    • doi:10.1016/j.febslet.2009.04.049
    • Waters, S., K. Marchbank, E. Solomon, C. Whitehouse, and M. Gautel. 2009. Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover. FEBS Lett. 583:1846-1852. doi:10.1016/j.febslet.2009.04.049
    • (2009) FEBS Lett , vol.583 , pp. 1846-1852
    • Waters, S.1    Marchbank, K.2    Solomon, E.3    Whitehouse, C.4    Gautel, M.5
  • 44
    • 0037119950 scopus 로고    scopus 로고
    • Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling
    • doi:10.1093/emboj/cdf493
    • Wong, E.S., C.W. Fong, J. Lim, P. Yusoff, B.C. Low, W.Y. Langdon, and G.R. Guy. 2002. Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling. EMBO J. 21:4796-4808. doi:10.1093/emboj/cdf493
    • (2002) EMBO J , vol.21 , pp. 4796-4808
    • Wong, E.S.1    Fong, C.W.2    Lim, J.3    Yusoff, P.4    Low, B.C.5    Langdon, W.Y.6    Guy, G.R.7
  • 45
    • 0035911147 scopus 로고    scopus 로고
    • A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment
    • doi:10.1083/jcb.152.4.765
    • Wunderlich, W., I. Fialka, D. Teis, A. Alpi, A. Pfeifer, R.G. Parton, F. Lottspeich, and L.A. Huber. 2001. A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment. J. Cell Biol. 152:765-776. doi:10.1083/jcb.152.4.765
    • (2001) J. Cell Biol , vol.152 , pp. 765-776
    • Wunderlich, W.1    Fialka, I.2    Teis, D.3    Alpi, A.4    Pfeifer, A.5    Parton, R.G.6    Lottspeich, F.7    Huber, L.A.8
  • 46
    • 0035933734 scopus 로고    scopus 로고
    • The C terminus of sprouty is important for modulation of cellular migration and proliferation
    • doi:10.1074/jbc.M100123200
    • Yigzaw, Y., L. Cartin, S. Pierre, K. Scholich, and T.B. Patel. 2001. The C terminus of sprouty is important for modulation of cellular migration and proliferation. J. Biol. Chem. 276:22742-22747. doi:10.1074/jbc.M100123200
    • (2001) J. Biol. Chem , vol.276 , pp. 22742-22747
    • Yigzaw, Y.1    Cartin, L.2    Pierre, S.3    Scholich, K.4    Patel, T.B.5
  • 47
    • 33749836283 scopus 로고    scopus 로고
    • Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors
    • doi:10.1038/sj.onc.1209635
    • Yoshida, T., T. Hisamoto, J. Akiba, H. Koga, K. Nakamura, Y. Tokunaga, S. Hanada, H. Kumemura, M. Maeyama, M. Harada, et al. 2006. Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors. Oncogene. 25:6056-6066. doi:10.1038/sj.onc.1209635
    • (2006) Oncogene , vol.25 , pp. 6056-6066
    • Yoshida, T.1    Hisamoto, T.2    Akiba, J.3    Koga, H.4    Nakamura, K.5    Tokunaga, Y.6    Hanada, S.7    Kumemura, H.8    Maeyama, M.9    Harada, M.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.