Gene disruption of Spred-2 causes dwarfism

Journal of Biological Chemistry

Volumn 280, Issue 31, 2005, Pages 28572-28580

  Bundschu, Karin ^a   Knobeloch, Klaus Peter ^b   Ullrich, Melanie ^a   Schinke, Thorsten ^c   Amling, Michael ^c   Engelhardt, Catherine M ^a   Renné, Thomas ^a   Walter, Ulrich ^a   Schuh, Kai ^a  

^a UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^b LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^c Experimentelle Unfallchirurgie   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELLS; CYTOLOGY; GENES; GENETIC ENGINEERING; GROWTH KINETICS;

BONE GROWTH; FIBROBLAST; FIBROBLAST GROWTH FACTORS (FGF); MUTATIONS;

BONE;

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1;

ACHONDROPLASIA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE GROWTH; CARTILAGE CELL; CELL STIMULATION; CONTROLLED STUDY; DWARFISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE; GENE DISRUPTION; GENE LOSS; GENE MUTATION; GENE OVEREXPRESSION; GROWTH PLATE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPRED 2 GENE; WILD TYPE;

EID: 23344432617     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M503640200     Document Type: Article

References (60)

1. Kronenberg, H. M. (2003) Nature. 423, 332-336
2. Goldfarb, M. (1996) Cytokine Growth Factor Rev. 7, 311-325
3. Basilico, C., and Moscatelli, D. (1992) Adv. Cancer Res. 59, 115-165
4. Peters, K., Ornitz, D., Werner, S., and Williams, L. (1993) Dev. Biol. 155, 423-430
5. Naski, M. C., and Ornitz, D. M. (1998) Front. Biosci. 3, D781-794
6. Ohbayashi, N., Shibayama, M., Kurotaki, Y., Imanishi, M., Fujimori, T., Itoh, N., and Takada, S. (2002) Genes Dev. 16, 870-879
7. Rousseau, F., Bonaventure, J., Legeai-Mallet, L., Pelet, A., Rozet, J. M., Maroteaux, P., Le Merrer, M., and Munnich, A. (1994) Nature 371, 252-254
8. Shiang, R., Thompson, L. M., Zhu, Y. Z., Church, D. M., Fielder, T. J., Bocian, M., Winokur, S. T., and Wasmuth, J. J. (1994) Cell 78, 335-342
9. Bellus, G. A., McIntosh, I., Smith, E. A., Aylsworth, A. S., Kaitila, I., Horton, W. A., Greenhaw, G. A., Hecht, J. T., and Francomano, C. A. (1995) Nat. Genet. 10, 357-359
10. Tavormina, P. L., Shiang, R., Thompson, L. M., Zhu, Y. Z., Wilkin, D. J., Lachman, R. S., Wilcox, W. R., Rimoin, D. L., Cohn, D. H., and Wasmuth, J. J. (1995) Nat. Genet. 9, 321-328
11. Oberklaid, F., Danks, D. M., Jensen, F., Stace, L., and Rosshandler, S. (1979) J. Med. Genet. 16, 140-146
12. Li, C., Chen, L., Iwata, T., Kitagawa, M., Fu, X. Y., and Deng, C. X. (1999) Hum. Mol. Genet. 8, 35-44
13. Wang, Y., Spatz, M. K., Kannan, K., Hayk, H., Avivi, A., Gorivodsky, M., Pines, M., Yayon, A., Lonai, P., and Givol, D. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 4455-4460
14. Iwata, T., Chen, L., Li, C., Ovchinnikov, D. A., Behringer, R. R., Francomano, C. A., and Deng, C. X. (2000) Hum. Mol. Genet. 9, 1603-1613
15. Iwata, T., Li, C. L., Deng, C. X., and Francomano, C. A. (2001) Hum. Mol. Genet. 10, 1255-1264
16. Segev, O., Chumakov, I., Nevo, Z., Givol, D., Madar-Shapiro, L., Sheinin, Y., Weinreb, M., and Yayon, A. (2000) Hum. Mol. Genet. 9, 249-258
17. Chen, L., Li, C., Qiao, W., Xu, X., and Deng, C. (2001) Hum. Mol. Genet. 10, 457-465
18. Colvin, J. S., Bohne, B. A., Harding, G. W., McEwen, D. G., and Ornitz, D. M. (1996) Nat. Genet. 12, 390-397
19. Deng, C., Wynshaw-Boris, A., Zhou, F., Kuo, A., and Leder, P. (1996) Cell 84, 911-921
20. Coffin, J. D., Florkiewicz, R. Z., Neumann, J., Mort-Hopkins, T., Dorn, G. W., 2nd, Lightfoot, P., German, R., Howles, P. N., Kier, A., and O'Toole, B. A. (1995) Mol. Biol. Cell 6, 1861-1873
21. Garofalo, S., Kliger-Spatz, M., Cooke, J. L., Wolstin, O., Lunstrum, G. P., Moshkovitz, S. M., Horton, W. A., and Yayon, A. (1999) J. Bone Miner. Res. 14, 1909-1915
22. Liu, Z., Xu, J., Colvin, J. S., and Ornitz, D. M. (2002) Genes Dev. 16, 859-869
23. Sahni, M., Ambrosetti, D. C., Mansukhani, A., Gertner, R., Levy, D., and Basilico, C. (1999) Genes Dev. 13, 1361-1366
24. Weksler, N. B., Lunstrum, G. P., Reid, E. S., and Horton, W. A. (1999) Biochem. J. 342, 677-682
25. Kanai, M., Goke, M., Tsunekawa, S., and Podolsky, D. K. (1997) J. Biol. Chem. 272, 6621-6628
26. Su, W. C., Kitagawa, M., Xue, N., Xie, B., Garofalo, S., Cho, J., Deng, C., Horton, W. A., and Fu, X. Y. (1997) Nature 386, 288-292
27. Legeai-Mallet, L., Benoist-Lasselin, C., Delezoide, A. L., Munnich, A., and Bonaventure, J. (1998) J. Biol. Chem. 273, 13007-13014
28. Hart, K. C., Robertson, S. C., Kanemitsu, M. Y., Meyer, A. N., Tynan, J. A., and Donoghue, D. J. (2000) Oncogene 19, 3309-3320
29. Choi, D. Y., Toledo-Aral, J. J., Lin, H. Y., Ischenko, I., Medina, L., Safo, P., Mandel, G., Levinson, S. R., Halegoua, S., and Hayman, M. J. (2001) J. Biol. Chem. 276, 5116-5122
30. Murakami, S., Kan, M., McKeehan, W. L., and de Crombrugghe, B. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 1113-1118
31. Kong, M., Wang, C. S., and Donoghue, D. J. (2002) J. Biol. Chem. 277, 15962-15970
32. Murakami, S., Balmes, G., McKinney, S., Zhang, Z., Givol, D., and de Crombrugghe, B. (2004) Genes Dev. 18, 290-305
33. Yasoda, A., Komatsu, Y., Chusho, H., Miyazawa, T., Ozasa, A., Miura, M., Kurihara, T., Rogi, T., Tanaka, S., Suda, M., Tamura, N., Ogawa, Y., and Nakao, K. (2004) Nat. Med. 10, 80-86
34. Koike, M., Yamanaka, Y., Inoue, M., Tanaka, H., Nishimura, R., and Seino, Y. (2003) J. Bone Miner. Res. 18, 2043-2051
35. Wakioka, T., Sasaki, A., Kato, R., Shouda, T., Matsumoto, A., Miyoshi, K., Tsuneoka, M., Komiya, S., Baron, R., and Yoshimura, A. (2001) Nature 412, 647-651
36. Minowada, G., Jarvis, L. A., Chi, C. L., Neubuser, A., Sun, X., Hacohen, N., Krasnow, M. A., and Martin, G. E. (1999) Development 126, 4465-4475
37. Hacohen, N., Kramer, S., Sutherland, D., Hiromi, Y., and Krasnow, M. A. (1998) Cell 92, 253-263
38. Lee, S. H., Schloss, D. J., Jarvis, L., Krasnow, M. A., and Swain, J. L. (2001) J. Biol. Chem. 276, 4128-4133
39. Sasaki, A., Taketomi, T., Wakioka, T., Kato, E., and Yoshimura, A. (2001) J. Biol. Chem. 276, 36804-36808
40. Miyoshi, K., Wakioka, T., Nishinakamura, H., Kamio, M., Yang, L., Inoue, M., Hasegawa, M., Yonemitsu, Y., Komiya, S., and Yoshimura, A. (2004) Oncogene 23, 5567-5576
41. Kato, R., Nonami, A., Taketomi, T., Wakioka, T., Kuroiwa, A., Matsuda, Y., and Yoshimura, A. (2003) Biochem. Biophys. Res. Commun. 302, 767-772
42. Engelhardt, C. M., Bundschu, K., Messerschmitt, M., Renne, T., Walter, U., Reinhard, M., and Schuh, K. (2004) Histochem. Cell Biol. 122, 527-538
43. Hashimoto, S., Nakano, H., Singh, G., and Katyal, S. (2002) Mech. Dev. 119, Suppl. 1, S303-S309
44. Nobuhisa, I., Kato, R., Inoue, H., Takizawa, M., Okita, K., Yoshimura, A., and Taga, T. (2004) J. Exp. Med. 199, 737-742
45. Nonami, A., Kato, R., Taniguchi, K., Yoshiga, D., Taketomi, T., Fukuyama, S., Harada, M., Sasaki, A., and Yoshimura, A. (2004) J. Biol. Chem. 279, 52543-52551
46. Inoue, H., Kato, R., Fukuyama, S., Nonami, A., Taniguchi, K., Matsumoto, K., Nakano, T., Tsuda, M., Matsumura, M., Kubo, M., Ishikawa, F., Moon, B. G., Takatsu, K., Nakanishi, Y., and Yoshimura, A. (2005) J. Exp. Med. 201, 73-82
47. Amling, M., Priemel, M., Holzmann, T., Chapin, K., Rueger, J. M., Baron, R., and Demay, M. B. (1999) Endocrinology 140, 4982-4987
48. DeMille, M. M., Kimmel, B. E., and Rubin, G. M. (1996) Gene (Amst.) 183, 103-108
49. Ball, L. J., Jarchau, T., Oschkinat, H., and Walter, U. (2002) FEBS Lett. 513, 45-52
50. Reinhard, M., Jarchau, T., and Walter, U. (2001) Trends Biochem. Sci. 26, 243-249
51. Christofori, G. (2003) Nat. Cell Biol. 5, 377-379
52. Kim, H. J., and Bar-Sagi, D. (2004) Nat. Rev. Mol. Cell. Biol. 5, 441-450
53. Callebaut, I., Cossart, P., and Dehoux, P. (1998) FEBS Lett. 441, 181-185
54. Zimmermann, J., Jarchau, T., Walter, U., Oschkinat, H., and Ball, L. J. (2004) J. Biomol. NMR 29, 435-436
55. Eigenthaler, M., Engelhardt, S., Schinke, B., Kobsar, A., Schmitteckert, E., Gambaryan, S., Engelhardt, C. M., Krenn, V., Eliava, M., Jarchau, T., Lohse, M. J., Walter, U., and Hein, L. (2003) Am. J. Physiol. 285, H2471-H2481
56. Aszodi, A., Pfeifer, A., Ahmad, M., Glauner, M., Zhou, X. H., Ny, L., Andersson, K. E., Kehrel, B., Offermanns, S., and Fassler, R. (1999) EMBO J. 18, 37-48
57. Hauser, W., Knobeloch, K. P., Eigenthaler, M., Gambaryan, S., Krenn, V., Geiger, J., Glazova, M., Rohde, E., Horak, I., Walter, U., and Zimmer, M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 8120-8125
58. Lanier, L. M., Gates, M. A., Witke, W., Menzies, A. S., Wehman, A. M., Macklis, J. D., Kwiatkowski, D., Soriano, P., and Gertler, F. B. (1999) Neuron 22, 313-325
59. Menzies, A. S., Aszodi, A., Williams, S. E., Pfeifer, A., Wehman, A. M., Goh, K. L., Mason, C. A., Fassler, R., and Gertler, F. B. (2004) J. Neurosci. 24, 8029-8038
60. Vasioukhin, V., Bauer, C., Yin, M., and Fuchs, E. (2000) Cell 100, 209-219