메뉴 건너뛰기




Volumn 183, Issue 7, 2009, Pages 4346-4359

Induction of alloantigen-specific human T regulatory cells by vasoactive intestinal peptide

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN D3; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN E; CYTOKINE; PROTEIN P27; TRANSCRIPTION FACTOR FOXP3; VASOACTIVE INTESTINAL POLYPEPTIDE; EPITOPE; GROWTH INHIBITOR;

EID: 70449707793     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0900400     Document Type: Article
Times cited : (42)

References (62)
  • 2
    • 8544242704 scopus 로고    scopus 로고
    • Regulatory T cells: Friend or foe in immunity to infection?
    • Mills, K. H. 2004. Regulatory T cells: friend or foe in immunity to infection? Nat. Rev. Immunol. 4: 841-855.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 841-855
    • Mills, K.H.1
  • 3
    • 17144374934 scopus 로고    scopus 로고
    • Regulatory T-cell therapy: Is it ready for the clinic?
    • Bluestone, J. A. 2005. Regulatory T-cell therapy: is it ready for the clinic? Nat. Rev. Immunol. 5: 343-349.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 343-349
    • Bluestone, J.A.1
  • 4
    • 44849089444 scopus 로고    scopus 로고
    • Regulatory T cells and immune computation
    • Quintana, F. J., and I. R. Cohen. 2008. Regulatory T cells and immune computation. Eur. J. Immunol. 38: 903-907.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 903-907
    • Quintana, F.J.1    Cohen, I.R.2
  • 5
    • 33747143361 scopus 로고    scopus 로고
    • From vanilla to 28 flavors: Multiple varieties of T regulatory cells
    • Shevach, E. M. 2006. From vanilla to 28 flavors: multiple varieties of T regulatory cells. Immunity 25: 195-201.
    • (2006) Immunity , vol.25 , pp. 195-201
    • Shevach, E.M.1
  • 7
    • 0029954330 scopus 로고    scopus 로고
    • Treatment of donor mice with an αβ T-cell receptor monoclonal antibody induces prolonged T-cell nonresponsiveness and effectively prevents lethal graft-versus-host disease in murine recipients of major histocompatibility complex (MHC)-matched and MHC-mismatched donor marrow grafts
    • Drobyski, W. R., and D. Majewski. 1996. Treatment of donor mice with an αβ T-cell receptor monoclonal antibody induces prolonged T-cell nonresponsiveness and effectively prevents lethal graft-versus-host disease in murine recipients of major histocompatibility complex (MHC)-matched and MHC-mismatched donor marrow grafts. Blood 87: 5355-5369.
    • (1996) Blood , vol.87 , pp. 5355-5369
    • Drobyski, W.R.1    Majewski, D.2
  • 9
    • 3242677783 scopus 로고    scopus 로고
    • Regulatory T cells and tolerogenic dendritic cells: From basic biology to clinical applications
    • DOI 10.1016/j.imlet.2004.04.015, PII S0165247804001166
    • Rutella, S., and R. M. Lemoli. 2004. Regulatory T cells and tolerogenic dendritic cells: from basic biology to clinical applications. Immunol. Lett. 94: 11-26. (Pubitemid 38953707)
    • (2004) Immunology Letters , vol.94 , Issue.1-2 , pp. 11-26
    • Rutella, S.1    Lemoli, R.M.2
  • 10
    • 2642566879 scopus 로고    scopus 로고
    • The significance of vasoactive intestinal peptide in immunomodulation
    • DOI 10.1124/pr.56.2.7
    • Delgado, M., D. Pozo, and D. Ganea. 2004. The significance of vasoactive intestinal peptide in immunomodulation. Pharmacol. Rev. 56: 249-290. (Pubitemid 38720831)
    • (2004) Pharmacological Reviews , vol.56 , Issue.2 , pp. 249-290
    • Delgado, M.1    Pozo, D.2    Ganea, D.3
  • 11
    • 4344693080 scopus 로고    scopus 로고
    • The many faces of VIP in neuroimmunology: A cytokine rather a neuropeptide?
    • DOI 10.1096/fj.03-1440hyp
    • Pozo, D., and M. Delgado, M. 2004. The many faces of VIP in neuroimmunology: a cytokine rather a neuropeptide? FASEB J. 18: 1325-1334. (Pubitemid 39150347)
    • (2004) FASEB Journal , vol.18 , Issue.12 , pp. 1325-1334
    • Pozo, D.1    Delgado, M.2
  • 12
    • 33845900208 scopus 로고    scopus 로고
    • Regulation of immune tolerance by anti-inflammatory neuropeptides
    • DOI 10.1038/nri1984, PII NRI1984
    • Gonzalez-Rey, E., A. Chorny, and M. Delgado. 2007. Regulation of immune tolerance by anti-inflammatory neuropeptides. Nat. Rev. Immunol. 7: 52-63. (Pubitemid 46020827)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.1 , pp. 52-63
    • Gonzalez-Rey, E.1    Chorny, A.2    Delgado, M.3
  • 13
    • 34548448446 scopus 로고    scopus 로고
    • Tuning immune tolerance with vasoactive intestinal peptide: A new therapeutic approach for immune disorders
    • DOI 10.1016/j.peptides.2007.04.008, PII S0196978107001271
    • Pozo, D., E. Gonzalez-Rey, A. Chorny, P. Anderson, N. Varela, and M. Delgado. 2007. Tuning immune tolerance with vasoactive intestinal peptide: a new therapeutic approach for immune disorders. Peptides 28: 1833-1846. (Pubitemid 47361418)
    • (2007) Peptides , vol.28 , Issue.9 , pp. 1833-1846
    • Pozo, D.1    Gonzalez-Rey, E.2    Chorny, A.3    Anderson, P.4    Varela, N.5    Delgado, M.6
  • 14
    • 34249682608 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and regulatory T-cell induction: A new mechanism and therapeutic potential for immune homeostasis
    • DOI 10.1016/j.molmed.2007.04.003, PII S1471491407000676
    • Gonzalez-Rey, E., and M. Delgado. 2007. Vasoactive intestinal peptide and regulatory T-cell induction: a new mechanism and therapeutic potential for immune homeostasis. Trends Mol. Med. 13: 241-251. (Pubitemid 46836872)
    • (2007) Trends in Molecular Medicine , vol.13 , Issue.6 , pp. 241-251
    • Gonzalez-Rey, E.1    Delgado, M.2
  • 16
    • 32944458828 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide induces regulatory T cells during experimental autoimmune encephalomyelitis
    • DOI 10.1002/eji.200535430
    • Fernandez-Martin, A., E. Gonzalez-Rey, A. Chorny, D. Ganea, and M. Delgado. 2006. Vasoactive intestinal peptide induces regulatory T cells during experimental autoimmune encephalomyelitis. Eur. J. Immunol. 36: 318-326. (Pubitemid 43257454)
    • (2006) European Journal of Immunology , vol.36 , Issue.2 , pp. 318-326
    • Fernadez-Martin, A.1    Gonzalez-Rey, E.2    Chorny, A.3    Ganea, D.4    Delgado, M.5
  • 18
    • 0035808447 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit nuclear factor-κB-dependent gene activation at multiple levels in the human monocytic cell line THP-1
    • Delgado, M., and D. Ganea. 2001. Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit nuclear factor-κB-dependent gene activation at multiple levels in the human monocytic cell line THP-1. J. Biol. Chem. 276: 369-380.
    • (2001) J. Biol. Chem. , vol.276 , pp. 369-380
    • Delgado, M.1    Ganea, D.2
  • 19
    • 35448930435 scopus 로고    scopus 로고
    • +FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-β dependent but does not confer a regulatory phenotype
    • +FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-β dependent but does not confer a regulatory phenotype. Blood 110: 2983-2990.
    • (2007) Blood , vol.110 , pp. 2983-2990
    • Tran, D.Q.1    Ramsey, H.2    Shevach, E.M.3
  • 22
    • 33645916180 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide induces regulatory dendritic cells that prevent acute graft-versus-host disease while maintaining the graft-versus-tumor response
    • Chorny, A., E. Gonzalez-Rey, A. Fernandez-Martin, D. Ganea, and M. Delgado. 2006. Vasoactive intestinal peptide induces regulatory dendritic cells that prevent acute graft-versus-host disease while maintaining the graft-versus-tumor response. Blood 107: 3787-3794.
    • (2006) Blood , vol.107 , pp. 3787-3794
    • Chorny, A.1    Gonzalez-Rey, E.2    Fernandez-Martin, A.3    Ganea, D.4    Delgado, M.5
  • 23
  • 24
    • 0035863749 scopus 로고    scopus 로고
    • Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-β-treated alloreactive T cells that do not induce graft-versus-host disease
    • Boussiotis, V. A., Z. M. Chen, J. C. Zeller, W. J. Murphy, A. Berezovskaya, S. Narula, M. G. Roncarolo, and B. R. Blazar. 2001. Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-β-treated alloreactive T cells that do not induce graft-versus-host disease. Blood 97: 565-571.
    • (2001) Blood , vol.97 , pp. 565-571
    • Boussiotis, V.A.1    Chen, Z.M.2    Zeller, J.C.3    Murphy, W.J.4    Berezovskaya, A.5    Narula, S.6    Roncarolo, M.G.7    Blazar, B.R.8
  • 25
    • 0033621780 scopus 로고    scopus 로고
    • p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes
    • Boussiotis, V. A., G. J. Freeman, P. A. Taylor, A. Berezovskaya, I. Grass, B. R. Blazar, and L. M. Nadler. 2000. p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes. Nat. Med. 6: 290-297.
    • (2000) Nat. Med. , vol.6 , pp. 290-297
    • Boussiotis, V.A.1    Freeman, G.J.2    Taylor, P.A.3    Berezovskaya, A.4    Grass, I.5    Blazar, B.R.6    Nadler, L.M.7
  • 28
    • 43549112146 scopus 로고    scopus 로고
    • FoxP3 maintains Treg unresponsiveness by selectively inhibiting the promoter DNA-binding activity of AP-1
    • Lee, S. M., B. Gao, and D. Fang. 2008. FoxP3 maintains Treg unresponsiveness by selectively inhibiting the promoter DNA-binding activity of AP-1. Blood 111: 3599-3606.
    • (2008) Blood , vol.111 , pp. 3599-3606
    • Lee, S.M.1    Gao, B.2    Fang, D.3
  • 36
    • 0032146529 scopus 로고    scopus 로고
    • + T cells tolerized ex vivo to host alloantigen by anti-CD40 ligand (CD40L:CD154) antibody lose their graft-versus-host disease lethality capacity but retain nominal antigen responses
    • + T cells tolerized ex vivo to host alloantigen by anti-CD40 ligand (CD40L:CD154) antibody lose their graft-versus-host disease lethality capacity but retain nominal antigen responses. J. Clin. Invest. 102: 473-482.
    • (1998) J. Clin. Invest. , vol.102 , pp. 473-482
    • Blazar, B.R.1    Taylor, P.A.2    Noelle, R.J.3    Vallera, D.A.4
  • 37
    • 0033976064 scopus 로고    scopus 로고
    • CD28 costimulation mediates T cell expansion via IL-2-independent and IL-2-dependent regulation of cell cycle progression
    • Appleman, L. J., A. Berezovskaya, I. Grass, and V. A. Boussiotis. 2000. CD28 costimulation mediates T cell expansion via IL-2-independent and IL-2-dependent regulation of cell cycle progression. J. Immunol. 164: 144-151.
    • (2000) J. Immunol. , vol.164 , pp. 144-151
    • Appleman, L.J.1    Berezovskaya, A.2    Grass, I.3    Boussiotis, V.A.4
  • 38
    • 0034816198 scopus 로고    scopus 로고
    • Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1
    • Nakayama, K. I., S. Hatakeyama, and K. Nakayama. 2001. Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1. Biochem. Biophys. Res. Commun. 282: 853-860.
    • (2001) Biochem. Biophys. Res. Commun. , vol.282 , pp. 853-860
    • Nakayama, K.I.1    Hatakeyama, S.2    Nakayama, K.3
  • 39
    • 1842479209 scopus 로고    scopus 로고
    • Stopping and going with p27kip1
    • Assoian, R. K. 2004. Stopping and going with p27kip1. Dev. Cell 6: 458-459.
    • (2004) Dev. Cell , vol.6 , pp. 458-459
    • Assoian, R.K.1
  • 40
    • 0037304898 scopus 로고    scopus 로고
    • New roles for p21 and p27 cell-cycle inhibitors: A function for each cell compartment?
    • Coqueret, O. 2003. New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? Trends Cell Biol. 13: 65-70.
    • (2003) Trends Cell Biol. , vol.13 , pp. 65-70
    • Coqueret, O.1
  • 41
    • 37549000146 scopus 로고    scopus 로고
    • Interweaving the cell cycle machinery with cell differentiation
    • Miller, J. P., N. Yeh, A. Vidal, and A. Koff. 2007. Interweaving the cell cycle machinery with cell differentiation. Cell Cycle 6: 2932-2938.
    • (2007) Cell Cycle , vol.6 , pp. 2932-2938
    • Miller, J.P.1    Yeh, N.2    Vidal, A.3    Koff, A.4
  • 42
    • 0034682037 scopus 로고    scopus 로고
    • Cell-cycle inhibitors: Three families united by a common cause
    • Vidal, A., and A. Koff. 2000. Cell-cycle inhibitors: three families united by a common cause. Gene 247: 1-15.
    • (2000) Gene , vol.247 , pp. 1-15
    • Vidal, A.1    Koff, A.2
  • 43
    • 34548429606 scopus 로고    scopus 로고
    • Anti-inflammatory neuropeptide receptors: New therapeutic targets for immune disorders?
    • DOI 10.1016/j.tips.2007.07.001, PII S0165614707001800
    • Gonzalez-Rey, E., and M. Delgado. 2007. Anti-inflammatory neuropeptide receptors: new therapeutic targets for immune disorders? Trends Pharmacol. Sci. 28: 482-491. (Pubitemid 47368698)
    • (2007) Trends in Pharmacological Sciences , vol.28 , Issue.9 , pp. 482-491
    • Gonzalez-Rey, E.1    Delgado, M.2
  • 44
    • 34547214205 scopus 로고    scopus 로고
    • Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans
    • Roncarolo, M. G., and M. Battaglia. 2007. Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. Nat. Rev. Immunol. 7: 585-598.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 585-598
    • Roncarolo, M.G.1    Battaglia, M.2
  • 45
    • 44849129837 scopus 로고    scopus 로고
    • Regulatory T cells in the past and for the future
    • Sakaguchi, S. 2008. Regulatory T cells in the past and for the future. Eur. J. Immunol. 38: 901-937.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 901-937
    • Sakaguchi, S.1
  • 46
    • 34547749066 scopus 로고    scopus 로고
    • Emerging challenges in regulatory T cell function and biology
    • Sakaguchi, S., and F. Powrie. 2007. Emerging challenges in regulatory T cell function and biology. Science 317: 627-629.
    • (2007) Science , vol.317 , pp. 627-629
    • Sakaguchi, S.1    Powrie, F.2
  • 52
    • 44849133287 scopus 로고    scopus 로고
    • The critical contribution of TGF-β to the induction of Foxp3 expression and regulatory T cell function
    • Shevach, E. M., D. Q. Tran, T. S. Davidson, and J. Anderson. 2008. The critical contribution of TGF-β to the induction of Foxp3 expression and regulatory T cell function. Eur. J. Immunol. 38: 915-917.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 915-917
    • Shevach, E.M.1    Tran, D.Q.2    Davidson, T.S.3    Anderson, J.4
  • 54
    • 0030863161 scopus 로고    scopus 로고
    • Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway
    • Kawada, M., S. Yamagoe, Y. Murakami, K. Suzuki, S. Mizuno, and Y. Uehara. 1997. Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway. Oncogene 15: 629-637.
    • (1997) Oncogene , vol.15 , pp. 629-637
    • Kawada, M.1    Yamagoe, S.2    Murakami, Y.3    Suzuki, K.4    Mizuno, S.5    Uehara, Y.6
  • 55
    • 2342618936 scopus 로고    scopus 로고
    • Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression
    • Liang, J., and J. M. Slingerland. 2003. Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression. Cell Cycle 2: 339-345.
    • (2003) Cell Cycle , vol.2 , pp. 339-345
    • Liang, J.1    Slingerland, J.M.2
  • 56
    • 0037306635 scopus 로고    scopus 로고
    • CAMP inhibits both Ras and Rap1 activation in primary human T lymphocytes, but only Ras inhibition correlates with blockade of cell cycle progression
    • Grader-Beck, T., A. A. van Puijenbroek, L. M. Nadler, and V. A. Boussiotis. 2003. cAMP inhibits both Ras and Rap1 activation in primary human T lymphocytes, but only Ras inhibition correlates with blockade of cell cycle progression. Blood 101: 998-1006.
    • (2003) Blood , vol.101 , pp. 998-1006
    • Grader-Beck, T.1    Van Puijenbroek, A.A.2    Nadler, L.M.3    Boussiotis, V.A.4
  • 57
    • 0042476435 scopus 로고    scopus 로고
    • Sensitivity of IL-5 production to the cAMP-dependent pathway in human T cells is reduced by exogenous IL-2 in a phosphoinositide 3-kinase-dependent way
    • Heijink, I. H., H. F. Kauffman, D. S. Postma, J. G. de Monchy, and E. Vellenga. 2003. Sensitivity of IL-5 production to the cAMP-dependent pathway in human T cells is reduced by exogenous IL-2 in a phosphoinositide 3-kinase-dependent way. Eur. J. Immunol. 33: 2206-2215.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 2206-2215
    • Heijink, I.H.1    Kauffman, H.F.2    Postma, D.S.3    De Monchy, J.G.4    Vellenga, E.5
  • 58
    • 0034253267 scopus 로고    scopus 로고
    • cAMP-dependent protein kinase (PKA) inhibits T cell activation by phosphorylating Ser-43 of raf-1 in the MAPK/ERK pathway
    • Ramstad, C., V. Sundvold, H. K. Johansen, and T. Lea. 2000. cAMP-dependent protein kinase (PKA) inhibits T cell activation by phosphorylating Ser-43 of raf-1 in the MAPK/ERK pathway. Cell. Signal. 12: 557-563.
    • (2000) Cell. Signal. , vol.12 , pp. 557-563
    • Ramstad, C.1    Sundvold, V.2    Johansen, H.K.3    Lea, T.4
  • 62
    • 0035806323 scopus 로고    scopus 로고
    • + T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
    • + T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J. Exp. Med. 193: 1295-1302.
    • (2001) J. Exp. Med. , vol.193 , pp. 1295-1302
    • Levings, M.K.1    Sangregorio, R.2    Roncarolo, M.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.