메뉴 건너뛰기




Volumn 23, Issue 5, 1999, Pages 443-450

Prevention of graft-versus-host disease in high risk patients by depletion of CD4+ and reduction of CD8+ lymphocytes in the marrow graft

Author keywords

GVHD; Immunosuppression; Post transplant; Selective T cell depletion

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYCLOSPORIN A; IMMUNOSUPPRESSIVE AGENT; METHOTREXATE;

EID: 0033011056     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1701493     Document Type: Article
Times cited : (28)

References (42)
  • 1
    • 0026049124 scopus 로고
    • T-cell depletion of HLA-identical transplants in leukemia
    • Marmont A, Horowitz M, Gale RP et al. T-cell depletion of HLA-identical transplants in leukemia. Blood 1991; 78: 2120-2130.
    • (1991) Blood , vol.78 , pp. 2120-2130
    • Marmont, A.1    Horowitz, M.2    Gale, R.P.3
  • 2
    • 0022620989 scopus 로고
    • Treatment of donor bone marrow with monoclonal anti-T-cell antibody and complement for the prevention of graft-versus-host disease: A prospective, randomized, double-blind trial
    • Mitsuyasu RT, Champlin RE, Gale RP et al. Treatment of donor bone marrow with monoclonal anti-T-cell antibody and complement for the prevention of graft-versus-host disease: a prospective, randomized, double-blind trial. Ann Intern Med 1986; 105: 20-26.
    • (1986) Ann Intern Med , vol.105 , pp. 20-26
    • Mitsuyasu, R.T.1    Champlin, R.E.2    Gale, R.P.3
  • 3
    • 0023924847 scopus 로고
    • T-cell depletion with Campath-1 in allogeneic bone marrow transplantation
    • Hale G, Cobbold S, Waldmann H. T-cell depletion with Campath-1 in allogeneic bone marrow transplantation. Transplantation 1988; 45: 753-759.
    • (1988) Transplantation , vol.45 , pp. 753-759
    • Hale, G.1    Cobbold, S.2    Waldmann, H.3
  • 4
    • 0024427624 scopus 로고
    • Graft failure following T-cell depleted HLA-identical marrow transplants for leukemia: Analysis of risk factors and results of secondary transplants
    • Kernan N, Bordignon C, Heller G et al. Graft failure following T-cell depleted HLA-identical marrow transplants for leukemia: analysis of risk factors and results of secondary transplants. Blood 1989; 74: 2227-2236.
    • (1989) Blood , vol.74 , pp. 2227-2236
    • Kernan, N.1    Bordignon, C.2    Heller, G.3
  • 5
    • 0025324988 scopus 로고
    • + T lymphocytes for prevention of graft-versus-host disease after allogeneic bone marrow transplantation
    • + T lymphocytes for prevention of graft-versus-host disease after allogeneic bone marrow transplantation. Blood 1990; 76: 418-423.
    • (1990) Blood , vol.76 , pp. 418-423
    • Champlin, R.1    Ho, W.2    Gajewsky, J.3
  • 6
    • 0026021880 scopus 로고
    • Retention of graft-versus-leukemia using selective depletion of CD8-positive T lymphocytes for prevention of graft-versus-host disease following bone marrow transplantation for chronic myclogenous leukemia
    • Champlin R, Jansen J, Ho W et al. Retention of graft-versus-leukemia using selective depletion of CD8-positive T lymphocytes for prevention of graft-versus-host disease following bone marrow transplantation for chronic myclogenous leukemia. Transplant Proc 1991; 23: 1695-1696.
    • (1991) Transplant Proc , vol.23 , pp. 1695-1696
    • Champlin, R.1    Jansen, J.2    Ho, W.3
  • 7
    • 0028054895 scopus 로고
    • + cells for prevention of graft-versus-host disease after bone marrow transplantation
    • + cells for prevention of graft-versus-host disease after bone marrow transplantation. Transplantation 1994; 57: 82-87.
    • (1994) Transplantation , vol.57 , pp. 82-87
    • Nimer, S.1    Giorgi, J.2    Gajewsky, J.3
  • 8
    • 0009486129 scopus 로고
    • Selective T-cell depletion with CD8-conjugated magnetic beads in the prevention of graft-versus-host disease after allogeneic bone marrow transplantation
    • Jansen J, Hanks S, Akard L et al. Selective T-cell depletion with CD8-conjugated magnetic beads in the prevention of graft-versus-host disease after allogeneic bone marrow transplantation. Leukemia 1995; 9: 271-278.
    • (1995) Leukemia , vol.9 , pp. 271-278
    • Jansen, J.1    Hanks, S.2    Akard, L.3
  • 9
    • 0026045680 scopus 로고
    • Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: Effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies
    • Antin JH, Bierer BE, Smith BR et al. Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies. Blood 1991; 78: 2139-2149.
    • (1991) Blood , vol.78 , pp. 2139-2149
    • Antin, J.H.1    Bierer, B.E.2    Smith, B.R.3
  • 10
    • 0026773113 scopus 로고
    • Prevention of graft-versus-host disease by selective depletion of CD6-positive T lymphocytes from donor bone marrow
    • Soiffer RJ, Murray C, Mauch P et al. Prevention of graft-versus-host disease by selective depletion of CD6-positive T lymphocytes from donor bone marrow. J Clin Oncol 1992; 10: 1191-1200.
    • (1992) J Clin Oncol , vol.10 , pp. 1191-1200
    • Soiffer, R.J.1    Murray, C.2    Mauch, P.3
  • 11
    • 0028345004 scopus 로고
    • Allogeneic bone marrow transplantation with a fixed low number of T cells in the marrow graft
    • Verdonck L, Dekker A, de Gast G et al. Allogeneic bone marrow transplantation with a fixed low number of T cells in the marrow graft. Blood 1994; 83: 3090-3096.
    • (1994) Blood , vol.83 , pp. 3090-3096
    • Verdonck, L.1    Dekker, A.2    De Gast, G.3
  • 12
    • 0028179358 scopus 로고
    • Effect of T-cell depletion as graft-versus-host disease prophylaxis on engraftment, relapse, and disease-free survival in unrelated marrow transplantation for chronic myelogenous leukemia
    • Drobyski WR, Ash RC, Casper JT et al. Effect of T-cell depletion as graft-versus-host disease prophylaxis on engraftment, relapse, and disease-free survival in unrelated marrow transplantation for chronic myelogenous leukemia. Blood 1994; 83: 1980-1987.
    • (1994) Blood , vol.83 , pp. 1980-1987
    • Drobyski, W.R.1    Ash, R.C.2    Casper, J.T.3
  • 13
    • 0027294049 scopus 로고
    • Donor CD8 cells prevent allogeneic marrow graft rejection in mice. Potential implications for marrow transplantation in humans
    • Martin PJ, Donor CD8 cells prevent allogeneic marrow graft rejection in mice. Potential implications for marrow transplantation in humans. J Exp Med 1993; 178: 703-712.
    • (1993) J Exp Med , vol.178 , pp. 703-712
    • Martin, P.J.1
  • 14
    • 0028606385 scopus 로고
    • GVHD prophylaxis in CML: Complete depletion of CD4 cells and controlled numbers of CD8 lymphocytes in the donor marrow
    • Abstr.
    • Grañena A, Canals C, Picón M et al. GVHD prophylaxis in CML: complete depletion of CD4 cells and controlled numbers of CD8 lymphocytes in the donor marrow. Bone Marrow Transplant 1994; 14 (Suppl. 3): 85 (Abstr.).
    • (1994) Bone Marrow Transplant , vol.14 , Issue.SUPPL. 3 , pp. 85
    • Grañena, A.1    Canals, C.2    Picón, M.3
  • 15
    • 0344075161 scopus 로고    scopus 로고
    • + cells as a GVHD prophylaxis prevents graft failure in CML patients undergoing allogeneic BMT
    • Abstr.
    • + cells as a GVHD prophylaxis prevents graft failure in CML patients undergoing allogeneic BMT. Bone Marrow Transplant 1997; 19 (Suppl. 1): 27 (Abstr.).
    • (1997) Bone Marrow Transplant , vol.19 , Issue.SUPPL. 1 , pp. 27
    • Gallardo, D.1    García-López, J.2    Sureda, A.3
  • 17
    • 1842292199 scopus 로고    scopus 로고
    • + cells in the CD4-depleted graft prevent allogeneic marrow graft rejection and severe graft-versus-host disease for chronic myeloid leukemia patients in first chronic phase
    • + cells in the CD4-depleted graft prevent allogeneic marrow graft rejection and severe graft-versus-host disease for chronic myeloid leukemia patients in first chronic phase. Bone Marrow Transplant 1997; 20: 945-952.
    • (1997) Bone Marrow Transplant , vol.20 , pp. 945-952
    • Gallardo, D.1    García-Lopez, J.2    Sureda, A.3
  • 18
    • 0025726925 scopus 로고
    • Risk factors for acute graft-versus-host disease in histocompatible donor bone marrow transplantation
    • Weisdorf D, Hakke R, Blazar B et al. Risk factors for acute graft-versus-host disease in histocompatible donor bone marrow transplantation. Transplantation 1991; 51: 1197-1203.
    • (1991) Transplantation , vol.51 , pp. 1197-1203
    • Weisdorf, D.1    Hakke, R.2    Blazar, B.3
  • 19
    • 0021268573 scopus 로고
    • Predictive factors for acute graft-versus-host disease in patients transplanted with HLA-identical bone marrow
    • Bross DS, Tutschka PJ, Farmer ER et al. Predictive factors for acute graft-versus-host disease in patients transplanted with HLA-identical bone marrow. Blood 1984; 63: 1265-1270.
    • (1984) Blood , vol.63 , pp. 1265-1270
    • Bross, D.S.1    Tutschka, P.J.2    Farmer, E.R.3
  • 20
    • 0023636166 scopus 로고
    • Risk factors for acute graft-versus-host disease
    • Gale RP, Bortin MM, van Bekkum DW et al. Risk factors for acute graft-versus-host disease. Br J Haematol 1987; 67: 397-406.
    • (1987) Br J Haematol , vol.67 , pp. 397-406
    • Gale, R.P.1    Bortin, M.M.2    Van Bekkum, D.W.3
  • 21
    • 0025348066 scopus 로고
    • Previous donor pregnancy as a risk factor for acute graft-versus-host disease in patients with aplastic anemia treated by allogeneic marrow transplantation
    • Flowers MED, Pepe MS, Longton G et al. Previous donor pregnancy as a risk factor for acute graft-versus-host disease in patients with aplastic anemia treated by allogeneic marrow transplantation. Br J Haematol 1990; 74: 492-496.
    • (1990) Br J Haematol , vol.74 , pp. 492-496
    • Flowers, M.E.D.1    Pepe, M.S.2    Longton, G.3
  • 22
    • 0025978290 scopus 로고
    • Marrow transplantation from HLA-matched unrelated donors for treatment of hematologic malignancies
    • Beatty PG, Hansen JA, Longton GM et al. Marrow transplantation from HLA-matched unrelated donors for treatment of hematologic malignancies. Transplantation 1991; 51: 443-447.
    • (1991) Transplantation , vol.51 , pp. 443-447
    • Beatty, P.G.1    Hansen, J.A.2    Longton, G.M.3
  • 24
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988; 16: 1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 25
    • 3042871056 scopus 로고
    • Rapid typing of tandemly repeated hypervariable loci by the polymerase chain reaction: Application to the apolipoprotein B 3′ hypervariable region
    • Boerwinkle E, Xiong W, Fourest E, Chan L. Rapid typing of tandemly repeated hypervariable loci by the polymerase chain reaction: application to the apolipoprotein B 3′ hypervariable region. Proc Natl Acad Sci USA 1989; 86: 212-216.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 212-216
    • Boerwinkle, E.1    Xiong, W.2    Fourest, E.3    Chan, L.4
  • 26
    • 0025968683 scopus 로고
    • Analysis of the VNTR locus DIS80 by PCR followed by high-resolution PAGE
    • Budowle B, Chakraborty R, Giusti AM et al. Analysis of the VNTR locus DIS80 by PCR followed by high-resolution PAGE. Am J Hum Genet 1991; 48: 137-144.
    • (1991) Am J Hum Genet , vol.48 , pp. 137-144
    • Budowle, B.1    Chakraborty, R.2    Giusti, A.M.3
  • 27
    • 0027092058 scopus 로고
    • Myeloid and lymphoid chimerism after T-cell-depleted bone marrow transplantation: Evaluation of conditioning regimens using polymerase chain reaction to amplify human minisatellite regions of genomic DNA
    • Mackinnon S, Barnett L, Bourhis JH et al. Myeloid and lymphoid chimerism after T-cell-depleted bone marrow transplantation: evaluation of conditioning regimens using polymerase chain reaction to amplify human minisatellite regions of genomic DNA. Blood 1992; 80: 3235-3241.
    • (1992) Blood , vol.80 , pp. 3235-3241
    • Mackinnon, S.1    Barnett, L.2    Bourhis, J.H.3
  • 28
    • 0025796586 scopus 로고
    • Rapid PCR analysis of the St14 (DXs52) VNTR
    • Richards B, Heilig R, Oberle I et al. Rapid PCR analysis of the St14 (DXS52) VNTR. Nucleic Acids Res 1991; 19: 1994.
    • (1991) Nucleic Acids Res , vol.19 , pp. 1994
    • Richards, B.1    Heilig, R.2    Oberle, I.3
  • 29
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958: 53: 457-481.
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 30
    • 0000336139 scopus 로고
    • Regression models and life-tables
    • Cox DR. Regression models and life-tables. JR Stat Soc 1972; 34: 187-220.
    • (1972) JR Stat Soc , vol.34 , pp. 187-220
    • Cox, D.R.1
  • 31
    • 0021345180 scopus 로고
    • Depletion of T lymphocytes in donor marrow prevents significant graft-versus-host disease in matched allogeneic leukemic marrow transplant recipients
    • Prentice HG, Janossy G, Price-Jones L et al. Depletion of T lymphocytes in donor marrow prevents significant graft-versus-host disease in matched allogeneic leukemic marrow transplant recipients. Lancet 1984; 1: 472-475.
    • (1984) Lancet , vol.1 , pp. 472-475
    • Prentice, H.G.1    Janossy, G.2    Price-Jones, L.3
  • 32
    • 0021227678 scopus 로고
    • Elimination of graft-versus-host disease by in vitro depletion of alloreactive lymphocytes with a monoclonal rat anti-human lymphocyte antibody (Campath-1)
    • Waldmann HG, Hale G, Cividalli G et al. Elimination of graft-versus-host disease by in vitro depletion of alloreactive lymphocytes with a monoclonal rat anti-human lymphocyte antibody (Campath-1). Lancet 1984; 2: 483-486.
    • (1984) Lancet , vol.2 , pp. 483-486
    • Waldmann, H.G.1    Hale, G.2    Cividalli, G.3
  • 33
    • 0023196214 scopus 로고
    • + T cells to cause lethal graft-versus-host disease across minor histocompatibility barriers in mice
    • + T cells to cause lethal graft-versus-host disease across minor histocompatibility barriers in mice. J Exp Med 1987; 165: 1552-1564.
    • (1987) J Exp Med , vol.165 , pp. 1552-1564
    • Korngold, R.1    Sprent, J.2
  • 34
    • 0025330598 scopus 로고
    • Comparative effects of various T cell subtypes on GVHD in a murine model for MHC-matched unrelated donor transplant
    • OKunewick JP, Kochiban DL, Buffo MJ. Comparative effects of various T cell subtypes on GVHD in a murine model for MHC-matched unrelated donor transplant. Bone Marrow Transplant 1990; 5: 145-152.
    • (1990) Bone Marrow Transplant , vol.5 , pp. 145-152
    • Okunewick, J.P.1    Kochiban, D.L.2    Buffo, M.J.3
  • 35
    • 0023242018 scopus 로고
    • L3T4-positive T-cells participate in the induction of graft-vs-host disease in response to minor histocompatibility antigens
    • Hamilton BL. L3T4-positive T-cells participate in the induction of graft-vs-host disease in response to minor histocompatibility antigens. J Immunol 1987; 139: 2511-2515.
    • (1987) J Immunol , vol.139 , pp. 2511-2515
    • Hamilton, B.L.1
  • 36
    • 0023029402 scopus 로고
    • Leukaemic relapse following Campath-1 treated bone marrow transplantation for leukaemia
    • Pollard CM, Powles RL. Millar JL et al. Leukaemic relapse following Campath-1 treated bone marrow transplantation for leukaemia. Lancet 1986; 2: 1343-1344.
    • (1986) Lancet , vol.2 , pp. 1343-1344
    • Pollard, C.M.1    Powles, R.L.2    Millar, J.L.3
  • 37
    • 85004843106 scopus 로고
    • Donor marrow T cell depletion for prevention of GvHD without loss of the GvL effect. Current results in acute myeloblastic leukemia and future directions
    • Gale RP, Champlin RE (eds). Alan R Liss: New York
    • Prentice HG, Brenner MK. Donor marrow T cell depletion for prevention of GvHD without loss of the GvL effect. Current results in acute myeloblastic leukemia and future directions. In: Gale RP, Champlin RE (eds). Bone Marrow Transplantation: Current Controversies. Alan R Liss: New York, 1989, pp 117-125.
    • (1989) Bone Marrow Transplantation: Current Controversies , pp. 117-125
    • Prentice, H.G.1    Brenner, M.K.2
  • 38
    • 0026683644 scopus 로고
    • T-cell-depleted allogeneic bone marrow transplantation in adults with acute nonlymphocytic leukemia in first remission
    • Young JW, Papadopoulos EB, Cunningham I et al. T-cell-depleted allogeneic bone marrow transplantation in adults with acute nonlymphocytic leukemia in first remission. Blood 1992; 79: 3380-3387.
    • (1992) Blood , vol.79 , pp. 3380-3387
    • Young, J.W.1    Papadopoulos, E.B.2    Cunningham, I.3
  • 39
    • 0022965430 scopus 로고
    • Bone marrow transplantation for patient with chronic myeloid leukemia: T-cell depletion with Campath-1 reduces the incidence of graft-versus-host disease but may increase the risk of leukaemic relapse
    • Apperley JF, Jones L, Hale G et al. Bone marrow transplantation for patient with chronic myeloid leukemia: T-cell depletion with Campath-1 reduces the incidence of graft-versus-host disease but may increase the risk of leukaemic relapse. Bone Marrow Transplant 1986; 1: 53-66.
    • (1986) Bone Marrow Transplant , vol.1 , pp. 53-66
    • Apperley, J.F.1    Jones, L.2    Hale, G.3
  • 40
    • 0023690307 scopus 로고
    • Bone marrow transplantation for chronic myelogenous leukemia in chronic phase: Increased risk for relapse associated with T-cell depletion
    • Goldman JM, Gale RP, Horowitz MM et al. Bone marrow transplantation for chronic myelogenous leukemia in chronic phase: increased risk for relapse associated with T-cell depletion. Ann Intern Med 1988; 108: 806-814.
    • (1988) Ann Intern Med , vol.108 , pp. 806-814
    • Goldman, J.M.1    Gale, R.P.2    Horowitz, M.M.3
  • 41
    • 0029888468 scopus 로고    scopus 로고
    • + T lymphocytes can exert cytotoxicity to chronic myeloid leukemia cells processing and presenting exogenous antigen
    • + T lymphocytes can exert cytotoxicity to chronic myeloid leukemia cells processing and presenting exogenous antigen. Br J Haematol 1996; 93: 606-612.
    • (1996) Br J Haematol , vol.93 , pp. 606-612
    • Jiang, Y.Z.1    Mavroudis, D.2    Dermime, S.3
  • 42
    • 0028877241 scopus 로고
    • + lymphocyte lines generated in vitro against chronic myelogenous leukemia
    • + lymphocyte lines generated in vitro against chronic myelogenous leukemia. Exp Hematol 1995; 23: 1167-1172.
    • (1995) Exp Hematol , vol.23 , pp. 1167-1172
    • Jiang, Y.Z.1    Barret, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.