Dual regulation of dendritic morphogenesis in Drosophila by the COP9 signalosome

PLoS ONE

Volumn 4, Issue 10, 2009, Pages

  Djagaeva, Inna ^a   Doronkin, Sergey ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COP9 SIGNALOSOME; CULLIN; F BOX PROTEIN; NEDD8 PROTEIN; CSN5 PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; MULTIPROTEIN COMPLEX; NEDD8 PROTEIN, DROSOPHILA; PEPTIDE HYDROLASE; SIGNAL PEPTIDE; UBIQUITIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITE; DENDRITIC SPINE; DROSOPHILA; HETEROZYGOTE; LARVA; MORPHOGENESIS; NERVE CELL DIFFERENTIATION; NONHUMAN; PHENOTYPE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; ANIMAL; BIOLOGICAL MODEL; CROSS BREEDING; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; MUTATION; NERVE CELL; PHYSIOLOGY;

CUBITUS INTERRUPTUS;

ANIMALS; CROSSES, GENETIC; DENDRITES; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; MORPHOGENESIS; MULTIPROTEIN COMPLEXES; MUTATION; NEURONS; PEPTIDE HYDROLASES; PHENOTYPE; UBIQUITINS;

EID: 70449558124     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007577     Document Type: Article

References (59)

1. Knobloch M, Mansuy IM (2008) Dendritic spine loss and synaptic alterations in Alzheimer's disease. Mol Neurobiol 37: 73-82.
2. Walsh DM, Selkoe DJ (2004) Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron 44: 181-193.
3. Spires TL, Grote HE, Garry S, Cordery PM, Van Dellen A, et al. (2004) Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice. Eur J Neurosci 19: 2799-2807.
4. Ferrante RJ, Kowall NW, Richardson EP, Jr. (1991) Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: a combined study using the section-Golgi method and calbindin D28k immunocytochemistry. J Neurosci 11: 3877-3887.
5. Penzes P, Jones KA (2008) Dendritic spine dynamics-a key role for kalirin-7. Trends Neurosci 31: 419-427.
6. Dierssen M, Ramakers GJ (2006) Dendritic pathology in mental retardation: from molecular genetics to neurobiology. Genes Brain Behav 5 Suppl 2: 48-60.
7. Kaufmann WE, Moser HW (2000) Dendritic anomalies in disorders associated with mental retardation. Cereb Cortex 10: 981-991.
8. Kelleher RJ, 3rd, Bear MF (2008) The autistic neuron: troubled translation? Cell 135: 401-406.
9. Kennedy MB, Beale HC, Carlisle HJ, Washburn LR (2005) Integration of biochemical signalling in spines. Nat Rev Neurosci 6: 423-434.
10. Schubert V, Dotti CG (2007) Transmitting on actin: synaptic control of dendritic architecture. J Cell Sci 120: 205-212.
11. Hershko A, Ciechanover A (1998) The ubiquitin system. Annu Rev Biochem 67: 425-479.
12. Deshaies RJ (1999) SCF and Cullin/Ring H2-based ubiquitin ligases. Annu Rev Cell Dev Biol 15: 435-467.
13. Petroski MD, Deshaies RJ (2005) Function and regulation of cullin-RING ubiquitin ligases. Nat Rev Mol Cell Biol 6: 9-20.
14. Glickman MH, Ciechanover A (2002) The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82: 373-428.
15. Cope GA, Deshaies RJ (2003) COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases. Cell 114: 663-671.
16. Schwechheimer C (2004) The COP9 signalosome (CSN): an evolutionary conserved proteolysis regulator in eukaryotic development. Biochim Biophys Acta 1695: 45-54.
17. Wolf DA, Zhou C, Wee S (2003) The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases? Nat Cell Biol 5: 1029-1033.
18. Doronkin S, Djagaeva I, Beckendorf SK (2003) The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis. Dev Cell 4: 699-710.
19. Mikus P, Zundel W (2005) COPing with hypoxia. Semin Cell Dev Biol 16: 462-473.
20. Doronkin S, Djagaeva I, Beckendorf SK (2002) CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint. Development 129: 5053-5064.
21. Lyapina S, Cope G, Shevchenko A, Serino G, Tsuge T, et al. (2001) Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science 292: 1382-1385.
22. Cope GA, Suh GS, Aravind L, Schwarz SE, Zipursky SL, et al. (2002) Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science 298: 608-611.
23. Zhou C, Seibert V, Geyer R, Rhee E, Lyapina S, et al. (2001) The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p. BMC Biochem 2: 7.
24. Schwechheimer C, Serino G, Callis J, Crosby WL, Lyapina S, et al. (2001) Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response. Science 292: 1379-1382.
25. Richardson KS, Zundel W (2005) The emerging role of the COP9 signalosome in cancer. Mol Cancer Res 3: 645-653.
26. Suh GS, Poeck B, Chouard T, Oron E, Segal D, et al. (2002) Drosophila JAB1/CSN5 acts in photoreceptor cells to induce glial cells. Neuron 33: 35-46.
27. Knowles A, Koh K, Wu JT, Chien CT, Chamovitz DA, et al. (2009) The COP9 signalosome is required for light-dependent timeless degradation and Drosophila clock resetting. J Neurosci 29: 1152-1162.
28. Harari-Steinberg O, Cantera R, Denti S, Bianchi E, Oron E, et al. (2007) COP9 signalosome subunit 5 (CSN5/Jab1) regulates the development of the Drosophila immune system: effects on Cactus, Dorsal and hematopoiesis. Genes Cells 12: 183-195.
29. Potocki L, Chen KS, Lupski JR (1999) Subunit 3 of the COP9 signal transduction complex is conserved from plants to humans and maps within the smith-magenis syndrome critical region in 17p11.2. Genomics 57: 180-182.
30. Potocki L, Glaze D, Tan DX, Park SS, Kashork CD, et al. (2000) Circadian rhythm abnormalities of melatonin in Smith-Magenis syndrome. J Med Genet 37: 428-433.
31. Elsea SH, Mykytyn K, Ferrell K, Coulter KL, Das P, et al. (1999) Hemizygosity for the COP9 signalosome subunit gene, SGN3, in the Smith-Magenis syndrome. Am J Med Genet 87: 342-348.
32. Yan J, Walz K, Nakamura H, Carattini-Rivera S, Zhao Q, et al. (2003) COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast. Mol Cell Biol 23: 6798-6808.
33. Peyrl A, Weitzdoerfer R, Gulesserian T, Fountoulakis M, Lubec G (2002) Aberrant expression of signaling-related proteins 14-3-3 gamma and RACK1 in fetal Down syndrome brain (trisomy 21). Electrophoresis 23: 152-157.
34. Oono K, Yoneda T, Manabe T, Yamagishi S, Matsuda S, et al. (2004) JAB1 participates in unfolded protein responses by association and dissociation with IRE1. Neurochem Int 45: 765-772.
35. Akiyama H, Sugiyama A, Uzawa K, Fujisawa N, Tashiro Y, et al. (2003) Implication of Trip15/CSN2 in early stage of neuronal differentiation of P19 embryonal carcinoma cells. Brain Res Dev Brain Res 140: 45-56.
36. Dil Kuazi A, Kito K, Abe Y, Shin RW, Kamitani T, et al. (2003) NEDD8 protein is involved in ubiquitinated inclusion bodies. J Pathol 199: 259-266.
37. Mori F, Nishie M, Piao YS, Kito K, Kamitani T, et al. (2005) Accumulation of NEDD8 in neuronal and glial inclusions of neurodegenerative disorders. Neuropathol Appl Neurobiol 31: 53-61.
38. Tarpey PS, Raymond FL, O'Meara S, Edkins S, Teague J, et al. (2007) Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor. Am J Hum Genet 80: 345-352.
39. Zou Y, Liu Q, Chen B, Zhang X, Guo C, et al. (2007) Mutation in CUL4B, which encodes a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardation. Am J Hum Genet 80: 561-566.
40. Doronkin S, Reiter LT (2008) Drosophila orthologues to human disease genes: an update on progress. Prog Nucleic Acid Res Mol Biol 82: 1-32.
41. Bilen J, Bonini NM (2005) Drosophila as a model for human neurodegenerative disease. Annu Rev Genet 39: 153-171.
42. Parrish JZ, Emoto K, Kim MD, Jan YN (2007) Mechanisms that regulate establishment, maintenance, and remodeling of dendritic fields. Annu Rev Neurosci 30: 399-423.
43. Lee T, Luo L (1999) Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron 22: 451-461.
44. Sholl DA (1953) Dendritic organization in the neurons of the visual and motor cortices of the cat. J Anat 87: 387-406.
45. Grueber WB, Jan LY, Jan YN (2002) Tiling of the Drosophila epidermis by multidendritic sensory neurons. Development 129: 2867-2878.
46. Fuchs SY, Chen A, Xiong Y, Pan ZQ, Ronai Z (1999) HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin. Oncogene 18: 2039-2046.
47. Jiang J, Struhl G (1998) Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb. Nature 391: 493-496.
48. Smelkinson MG, Kalderon D (2006) Processing of the Drosophila hedgehog signaling effector Ci-155 to the repressor Ci-75 is mediated by direct binding to the SCF component Slimb. Curr Biol 16: 110-116.
49. Yu X, Malenka RC (2003) Beta-catenin is critical for dendritic morphogenesis. Nat Neurosci 6: 1169-1177.
50. Lum L, Beachy PA (2004) The Hedgehog response network: sensors, switches, and routers. Science 304: 1755-1759.
51. Kalderon D (2005) The mechanism of hedgehog signal transduction. Biochem Soc Trans 33: 1509-1512.
52. Parrish JZ, Kim MD, Jan LY, Jan YN (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-835.
53. Forbes AJ, Nakano Y, Taylor AM, Ingham PW (1993) Genetic analysis of hedgehog signalling in the Drosophila embryo. Dev Suppl. pp 115-124.
54. Alexandre C, Jacinto A, Ingham PW (1996) Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins. Genes Dev 10: 2003-2013.
55. Dominguez M, Brunner M, Hafen E, Basler K (1996) Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus. Science 272: 1621-1625.
56. Hepker J, Wang QT, Motzny CK, Holmgren R, Orenic TV (1997) Drosophila cubitus interruptus forms a negative feedback loop with patched and regulates expression of Hedgehog target genes. Development 124: 549-558.
57. Shin SH, Kogerman P, Lindstrom E, Toftgard R, Biesecker LG (1999) GLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localization. Proc Natl Acad Sci U S A 96: 2880-2884.
58. Wearne SL, Rodriguez A, Ehlenberger DB, Rocher AB, Henderson SC, et al. (2005) New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales. Neuroscience 136: 661-680.
59. Djagaeva I, Doronkin S (2009) COP9 limits dendritic branching via Cullin3-dependent degradation of the actin-crosslinking BTB-domain protein Kelch. PLoS ONE, In press.