Platelet MAO activity and the 5-HTT gene promoter polymorphism are associated with impulsivity and cognitive style in visual information processing

Psychopharmacology

Volumn 194, Issue 4, 2007, Pages 545-554

  Paaver, Marika ^a   Nordquist, Niklas ^b   Parik, Jüri ^a   Harro, Maarike ^c   Oreland, Lars ^b   Harro, Jaanus ^a  

^a UNIVERSITY OF TARTU   (Estonia)

^b UPPSALA UNIVERSITY   (Sweden)

^c NATIONAL INSTITUTE FOR HEALTH DEVELOPMENT   (Estonia)

Author keywords

5 HT transporter gene; Cognitive abilities; Impulsiveness; Platelet monoamine oxidase; Serotonin; Speed and accuracy of information processing

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); BIOLOGICAL MARKER; SEROTONIN TRANSPORTER;

ADOLESCENT; ALLELE; ANALYTICAL ERROR; ARTICLE; COGNITION; ENZYME ACTIVATION; FEMALE; GENETIC POLYMORPHISM; HUMAN; HUMAN EXPERIMENT; IMPULSIVENESS; MALE; MOLECULAR INTERACTION; NORMAL HUMAN; PRIORITY JOURNAL; PROMOTER REGION; RATING SCALE; SELF REPORT; TASK PERFORMANCE; THROMBOCYTE; VISUAL INFORMATION;

ADOLESCENT; ALLELES; BLOOD PLATELETS; COGNITION; FEMALE; GENOTYPE; HUMANS; IMPULSIVE BEHAVIOR; MALE; MENTAL PROCESSES; MONOAMINE OXIDASE; PATTERN RECOGNITION, VISUAL; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); PSYCHOLOGICAL TESTS; REACTION TIME; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; VISUAL PATHWAYS; VISUAL PERCEPTION;

EID: 34848919517     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-007-0867-z     Document Type: Article

References (65)

1. af Klinteberg B, Levander SE, Oreland L, Asberg M, Schalling D (1987) Neuropsychological correlates of platelet monoamine oxidase (MAO) activity in female and male subjects. Biol Psychol 24:237-252
2. af Klinteberg B, Oreland L, Hallman J, Wirsen A, Levander SE, Schalling D (1990) Exploring the connections between platelet monoamine oxidase activity and behaviour: relationships with performance in neuropsychological tasks. Neuropsychobiology 23:188-196
3. Amador-Campus J, Kirchner-Nebot T (2001) Childrens embedded figures test and matching familiar figures test-20: factorial structure for boys and girls from 6 to 11 years old. Percept Mot Skills 93:709-712
4. Baca-Garcia E, Salgadoa BR, Segala HD, Lorenzo CV, Acosta MN, Romeroa MA, Hernandez MD, Ruiza JS, Piqueras JF, de Leonc J (2005) A pilot genetic study of the continuum between compulsivity and impulsivity in females: The serotonin transporter promoter polymorphism. Prog Neuropsychopharmacol Biol Psychiatry 29:713-717
5. Barratt ES (1993) Impulsivity: integrating cognitive, behavioral, biological and environmental data. In: McCown WB, Johnson JL, Shure MB (eds) The impulsive client: theory, research and treatment. American Psychological Association, Washington, DC, pp 39-56
6. Bernfeld GA, Peters RV (1986) Social reasoning and social behaviour reflective and impulsive children. J Clin Child Psychol 15:221-227
7. Botvinick M, Nystrom LE, Fissell K, Carter CS, Cohen JD (1999) Conflict monitoring versus selection-for-action in anterior cingulate cortex. Nature 402:179-181
8. Brannigan GG, Ass T, Margolis H (1980) Impulsivity-relfectivity and children's intellectual performances. J Pers Assess 44:41-43
9. Brázdil M, Roman R, Daniel P, Rektor I (2005) Intracerebral error-related negativity in a simple Go/No-go task. J Psychophysiol 19:244-255
10. Brotman MA, Schmajuk M, Rich BA, Dickstein DP, Guyer AE, Costello EJ, Egger HL, Angold A, Pine DS, Leibenluft E (2006) Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in children. Biol Psychiatry 60:991-997
11. Brown GI, Ebert M, Goyer PF, Jimerson DC, Klwin WJ, Bunney WE, Goodwin FK (1982) Aggression, suicide, and serotonin: relationships to CSF amine metabolites. Am J Psychiatryyiatry 139:741-746
12. Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H, McClay J, Mill J, Martin J, Braithwaite A, Poulton R (2003) Influence of life stress on depression: moderation by a polymorphism in the 5-HTT. Science 301:386-389
13. Cherek DR, Lane SD (1999) Effects of d,l-fenfluramine on aggressive and impulsive responding in adult males with a history of conduct disorder. Psychopharmacology (Berl) 146:473-481
14. Clark L, Roiser JP, Cools R, Rubinsztein DC, Sahakian BJ, Robbins TW (2005) Stop signal response inhibition is not modulated by tryptophan depletion or the serotonin transporter polymorphism in healthy volunteers: implications for the 5-HT theory of impulsivity. Psychopharmacology (Berl) 182:570-578
15. Costa PT, McCrae RR (1989) The NEO-PI/NEO-FFI manual supplement. Psychological Assessment Resources, Odessa, FL
16. Dickman SJ (1990) Functional and dysfunctional impulsivity: personality and cognitive correlates. J Pers Soc Psychol 58:95-102
17. Dickman J (1993) Impulsivity and information processing. In: McCown WB, Johnson JL, Shure MB (eds) The impulsive client: theory, research and treatment. American Psychological Association, Washington, DC, pp 39-56
18. Dickman S, Meyer DE (1988) Impulsivity and speed-accuracy tradeoffs in information processing. J Pers Soc Psychol 54:274-290
19. Ebstein RP (2006) The molecular genetic architecture of human personality: beyond self-report questionnaires. Mol Psychiatry 11:427-445
20. Evenden JL (1999) Varieties of impulsivity. Psychopharmacology (Berl) 146:348-361
21. Fairbanks LA, Melega WP, Jorgensen MJ, Kaplan KR, McGuire MT (2001) Social impulsivity inversely associated with CSF 5-HIAA and fluoxetine exposure in vervet monkeys. Neuropsychopharmacology 24:370-378
22. Fallgatter AJ, Jatzke S, Bartsch AJ, Hamelbeck B, Lesch KP (1999) Serotonin transporter promoter polymorphism influences topography of inhibitory motor control. Int J Neuropsychopharmacology 2:115-120
23. 11c]mcn 5652. Am J Psychiatryyiatry 5:915-923
24. Galvan A, Hare TA, Parra CE, Penn J, Voss H, Glover G, Casey BJ (2006) Earlier development of the accumbens relative to orbitofrontal cortex might underlie risk-taking behavior in adolescents. J Neurosci 26:6885-6892
25. Gerra G, Garofano L, Santoro G, Bosari S, Pellegrini C, Zaimovic A, Moi G, Bussandri M, Moi A, Brambilla F, Donnini C (2004) Association between low-activity serotonin transporter genotype and heroin dependence: behavioral and personality correlates. Am J Med Genet 126B:37-42
26. Hallikainen T, Saito T, Lachman HM, Volavka J, Pojhanen T, Ryynänen OP, Kauhanen J, Syvälahti E, Hietala J, Tiihonen J (1999) Association between low activity serotonin transporter promoter genotype and early onset alcoholism with habitual impulsive violent behavior. Mol Psychiatry 4:385-388
27. Hallman J, Oreland L, Edman G, Schalling D (1987) Thrombocyte monoamine oxidase activity and personality traits in women with severe premenstrual syndrome. Acta Psychiatr Scand 76:225-234
28. Harrison BJ, Olver JS, Norman TR, Nathan PJ (2002) Brain monoamines and early visual information-processing speed. Int J Neuropsychopharmacol 5:295-300
29. Harro M, Eensoo D, Kiive E, Merenäkk L, Alep J, Oreland L, Harro J (2001) Platelet monoamine oxidase in healthy 9- and 15-years old children: the effect of gender, smoking and puberty. Prog Neuro-Psychopharmacol Biol Psychiatry 25:1497-1511
30. Harro J, Fischer K, Vansteelandt S, Harro M (2004) Both low and high activity of platelet monoamine oxidase increase the probability of becoming a smoker. Eur Neuropsychopharmacol 14:65-69
31. Hu XZ, Lipsky RH, Zhu G, Akhtar LA, Taubman J, Greenberg BD, Xu K, Arnold PD, Richter MA, Kennedy JL, Murphy DL, Goldman D (2006) Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Hum Genet 78:815-826
32. Jensen AR (1998) The g factor. Praeger, Westport, CT
33. Kagan J, Rosman B, Day D, Albert J, Phillips W (1964) Information processing in the child: Significance of analytic and reflective attitudes. Psychol Monogr, 78 (1, Whole no. 578)
34. Kiive E, Merenäkk L, Harro M, Harro J (2005) Changes in platelet monoamine oxidase activity, cholesterol levels and hyperactive behaviour in adolescents over a period of three years. Neurosci Lett 384:310-315
35. Lesch KP (2005) Alcohol dependence and gene x environment interaction in emotion regulation: Is serotonin the link? Eur J Pharmacol 526:113-124
36. Lesch KP, Gutknecht L (2005) Pharmacogenetics of the serotonin transporter. Prog Neuropsychopharmacol Biol Psychiatry 29:1062-1073
37. Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S, Benjamin J, Müller CR, Hamer DH, Murphy DL (1996) Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274:1527-1531
38. Lynn J, Allik J, Pullmann H, Laidra K (2002) A study of intelligence in Estonia. Psychol Rep 91:1022-1026
39. Messer SB, Brodzinsky DM (1981) Three-year stability of reflection-impulsivity in young adolescents. Dev Psychol 17:848-850
40. Milich R, Kramer J (1984) Reflections on impulsivity: An empirical investigation of impulsivity as a construct. Adv Learn Beh Disabil 3:57-94
41. Morgan MJ (1998) Recreational use of ecstasy (MDMA) is associated with elevated impulsivity. Neuropsychopharmacology 19:252-264
42. Murphy FC, Smith KA, Cowen PJ, Robbins TW, Sahakian BJ (2002) The effects of tryptophan depletion on cognitive and affective processing in healthy volunteers. Psychopharmacology (Berl) 163:42-53
43. Nelson RJ (2005) Biology of aggression. Oxford University Press, Cary, NC, USA, pp 79-84
44. Oreland L (2004) Platelet monoamine oxidase, personality and alcoholism: the rise, fall and resurrection. Neurotoxicology 25:79-89
45. Paaver M, Eensoo D, Pulver A, Harro J (2006a) Adaptive and maladaptive impulsivity, platelet monoamine oxidase (MAO) activity and risk-admitting in different types of risky drivers. Psychopharmacology (Berl) 186:32-40
46. Paaver M, Kreegipuu K, Tamm M, Harro M, Harro J (2006b) Platelet MAO activity is associated with vulnerability to fatigue and accuracy and speed of information processing in the tasks of visual cognition. Int J Neuropsychopharmacol 9:S200
47. Patton JH, Stanford MS, Barratt ES (1995) Factor structure of the Barratt Impulsiveness Scale. J Clin Psychol 51:768-774
48. Pezawas L, Meyer-Lindenberg A, Drabant EM, Verchinski BA, Munoz KE, Kolachana BS, Egan MF, Mattay VS, Hariri, AR, Weinberger DR (2005) 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. Nat Neurosci 8:828-834
49. 3H] paroxetine binding in healthy control subjects and alcohol-dependent patients and their relationships to impulsivity. Psychiatry Res 96:51-61
50. Raven J (1981) Manual for Raven's Progressive Matrices and Mill Hill vocabulary scales. Oxford Psychologists Press, Oxford
51. Reynolds B, Ortengren A, Richards JB, de Wit H (2006) Dimensions of impulsive behavior in personality and behavioral measures. Person Indiv Diff 40:305-315
52. Ruchkin VV, Koposov RA, af Klinteberg B, Oreland L, Grigorenko EL (2005) Platelet MAO-B, personality, and psychopathology. J Abnorm Psychol 114:477-482
53. Schalling D, Asberg M, Edman G, Oreland L (1987) Markers for vulnerability to psychopathology: temperament traits associated with platelet MAO activity. Acta Psychiatr Scand 176:172-182
54. Schalling D, Edman G, Asberg M, Oreland L (1988) Platelet MAO activity associated with impulsivity and aggressivity. Person Indiv Diff 9:597-605
55. Schmitt J, Jorissen B, Sobczak S, van Boxtel MPJ, Hogervorst E, Deutz NEP, Riedel W (2000) Tryptophan depletion impairs memory consolidation but improves focussed attention in healthy young volunteers. J Psychopharmacol 14:21-30
56. Shekim WO, Hodges K, Horwitz E, Glaser RD, Davis L, Bylund DB (1984) Psychoeducational and impulsivity correlates of platelet MAO in normal children. Psychiatry Res 11:99-106
57. Smeraldi E, Zanardi R, Benedetti F, DiBella D, Perez J, Catalano M (1998) Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine. Mol Psychiatry 3:508-511
58. Swann AC, Bjork JM Moeller FG, Dougherty DM (2002) Two models of impulsivity: relationship to personality traits and psychopathology. Biol Psychiatry 51:988-994
59. Talpos JC, Wilkinson LS, Robbins TW (2006) A comparison of multiple 5-HT receptors in two tasks measuring impulsivity. J Psychopharmacol 20:47-58
60. Taylor SE, Way BM, Welch WT, Hilmert CJ, Lehman BJ, Eisenberger NI (2006) Early family environment, current adversity, the serotonin transporter promoter polymorphism, and depressive symptomatology. Biol Psychiatry 60:671-676
61. Vigil-Colet A, Morales-Vives F (2005) How impulsivity is related to intelligence and academic achievement. Spanish J Psychol 8:199-204
62. von Knorring L, Oreland L, Winblad B (1984) Personality traits related to monoamine oxidase activity in platelets. Psychiatry Res 12:11-26
63. Walderhaug E, Lunde H, Nordvik JE, Landro NI, Refsum H, Magnusson A (2002) Lowering of serotonin by rapid tryptophan depletion increases impulsiveness in normal individuals. Psychopharmacology (Berl) 164:385-391
64. Wengland JR, Martin BJ, Kruse MR, Lesch KP, Murphy DL (2006) Simultaneous genotyping of four functional loci of human SLC6A4, with a reappraisal of 5-HTTLPR and rs25531. Mol Psychiatry 11:224-226
65. Yamamoto S, Ouchi Y, Onoe H, Yoshikawa E, Tsukada H, Takahashi H, Iwase M, Yamaguti K, Kuratsune H, Watanabe Y (2004) Reduction of serotonin transporters of patients with chronic fatigue syndrome. Neuroreport 15:2571-2574