The role of plasma proteins in brain targeting: Species dependent protein adsorption patterns on brain-specific lipid drug conjugate (LDC) nanoparticles

International Journal of Pharmaceutics

Volumn 214, Issue 1-2, 2001, Pages 87-91

  Gessner, A ^a   Olbrich, C ^a   Schroder W ^a   Kayser, O ^a   Muller R H ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Drug targeting; Nanoparticles; Protein adsorption; Trypanosomiasis; Two dimensional electrophoresis

Indexed keywords

ACRYLIC ACID DERIVATIVE; ALBUMIN; APOLIPOPROTEIN A1; APOLIPOPROTEIN A4; APOLIPOPROTEIN E; DRUG CARRIER; LEUCINE ENKEPHALIN[2 DEXTRO ALANINE 6 ARGININE]; MARKER; NALOXONE; NANOPARTICLE; PLASMA PROTEIN; POLY(BUTYL 2 CYANOACRYLATE); POLYSORBATE 80; SURAMIN; UNCLASSIFIED DRUG;

ADSORPTION; ANALYTIC METHOD; ANIMAL EXPERIMENT; BLOOD BRAIN BARRIER; CONFERENCE PAPER; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG DISTRIBUTION; DRUG TARGETING; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SERUM; SPECIES DIFFERENCE; TRYPANOSOMIASIS;

ADSORPTION; ANIMALS; APOLIPOPROTEIN A-I; APOLIPOPROTEINS A; APOLIPOPROTEINS E; BLOOD PROTEINS; BLOOD-BRAIN BARRIER; BRAIN; DRUG DELIVERY SYSTEMS; HUMANS; MICE; SPECIES SPECIFICITY;

EID: 0035910874     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00639-6     Document Type: Conference Paper

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